نتائج البحث - "genetics [Interleukin-1beta]"

1

STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression

المؤلفون: W. Samantha N. Jayasekara, Cynthia Louis, Hassan Albargy, Kevin Luu, Katherine A. Fitzgerald, Francis J. Kirby, Finbar Mansell, Jesse J. Balic, Daniel J. Garama, Eicke Latz, Fiachra Humphries, Ashley Mansell, Nikola Baschuk, Daniel J. Gough, Dominic De Nardo

المصدر: Nature Communications 11(1), 3816 (2020). doi:10.1038/s41467-020-17669-5
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)

مصطلحات موضوعية: 0301 basic medicine, Lipopolysaccharides, medicine.medical_treatment, Interleukin-1beta, metabolism [Toll-Like Receptor 4], genetics [Interleukin-1beta], General Physics and Astronomy, Gene Expression, 0302 clinical medicine, metabolism [Protein Serine-Threonine Kinases], metabolism [STAT3 Transcription Factor], Serine, Glycolysis, Phosphorylation, lcsh:Science, Cells, Cultured, Mice, Knockout, metabolism [Inflammation], drug effects [Macrophages], Multidisciplinary, Chemistry, metabolism [Serine], genetics [Serine], Warburg effect, Cell biology, pharmacology [Lipopolysaccharides], Cytokine, metabolism [TNF Receptor-Associated Factor 6], lipids (amino acids, peptides, and proteins), ddc:500, medicine.symptom, drug effects [Glycolysis], Reprogramming, genetics [TNF Receptor-Associated Factor 6], Signal Transduction, STAT3 Transcription Factor, drug effects [Signal Transduction], Science, Inflammation, Mice, Transgenic, genetics [Protein Serine-Threonine Kinases], Protein Serine-Threonine Kinases, genetics [Signal Transduction], General Biochemistry, Genetics and Molecular Biology, Cell Line, 03 medical and health sciences, genetics [Inflammation], metabolism [Interleukin-1beta], medicine, Animals, TNF Receptor-Associated Factor 6, Macrophages, General Chemistry, genetics [STAT3 Transcription Factor], genetics [Toll-Like Receptor 4], Toll-Like Receptor 4, Mice, Inbred C57BL, 030104 developmental biology, Anaerobic glycolysis, TLR4, metabolism [Macrophages], lcsh:Q, Ex vivo, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d96f36776d72d1c4575633c91b3361

2

Traumatic brain injury causes long-term behavioral changes related to region-specific increases of cerebral blood flow

المؤلفون: Bruno Pöttker, Franziska Stöber, Michael K. E. Schäfer, Konstantin Radyushkin, Frank Angenstein, Jürgen Goldschmidt, Regina Hummel

المصدر: Brain structure & function 222(9), 4005-4021 (2017). doi:10.1007/s00429-017-1452-9

مصطلحات موضوعية: 0301 basic medicine, Neurology, metabolism [Interleukin-6], Interleukin-1beta, genetics [Interleukin-1beta], Morris water navigation task, Hippocampus, Mice, Epilepsy, 0302 clinical medicine, chemically induced [Seizures], Brain Injuries, Traumatic, Conditioning, Psychological, Trauma Severity Indices, Mental Disorders, General Neuroscience, Fear, Magnetic Resonance Imaging, Cerebral blood flow, Lcn2 protein, mouse, Cerebrovascular Circulation, diagnostic imaging [Seizures], Anatomy, medicine.symptom, physiology [Conditioning, Psychological], Psychology, etiology [Mental Disorders], medicine.medical_specialty, diagnostic imaging [Brain Injuries, Traumatic], Histology, Traumatic brain injury, metabolism [Lipocalin-2], genetics [Interleukin-6], Brain damage, physiology [Cerebrovascular Circulation], 03 medical and health sciences, metabolism [Interleukin-1beta], physiology [Maze Learning], Lipocalin-2, Seizures, Spect imaging, Glial Fibrillary Acidic Protein, medicine, Animals, ddc:610, Maze Learning, Tomography, Emission-Computed, Single-Photon, complications [Brain Injuries, Traumatic], toxicity [Pentylenetetrazole], Interleukin-6, metabolism [Glial Fibrillary Acidic Protein], medicine.disease, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, IL1B protein, mouse, Pentylenetetrazole, Neuroscience, physiology [Fear], Psychomotor Performance, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2cfa1f3ed15c57f480d6fd3bd88e017
https://doi.org/10.1007/s00429-017-1452-9

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3

New role of P2X7 receptor in an Alzheimer's disease mouse model

المؤلفون: Cécile Delarasse, Carine Dalle, Benoît Delatour, Annett Halle, Elodie Martin, Majid Amar, Jean Kanellopoulos, Véronique Sazdovitch, Bertrand Fontaine, Matthias Brückner, Ihsen Youssef, Annick Prigent, Céline Boucher, Caroline Le Duigou

المساهمون: Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute (ICM), Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Max Planck Research Group Neuroanatomy and Connectivity, Max Planck Institute for Human Cognitive and Brain Sciences [Leipzig] (IMPNSC), Max-Planck-Gesellschaft-Max-Planck-Gesellschaft, CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Centre de recherche en Myologie – U974 SU-INSERM, Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Institut du Cerveau = Paris Brain Institute (ICM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Centre de Recherche en Myologie

المصدر: Molecular Psychiatry
Molecular Psychiatry, Nature Publishing Group, In press, ⟨10.1038/s41380-018-0108-3⟩
Molecular psychiatry 24(1), 108-125 (2018). doi:10.1038/s41380-018-0108-3
Molecular Psychiatry, In press, ⟨10.1038/s41380-018-0108-3⟩

مصطلحات موضوعية: 0301 basic medicine, Inflammasomes, Physiology, metabolism [NLR Family, Pyrin Domain-Containing 3 Protein], [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, Interleukin-1beta, genetics [Interleukin-1beta], genetics [Alzheimer Disease], Diseases, metabolism [Receptors, Purinergic P2X7], APP protein, human, P2rx7 protein, mouse, Chemokine receptor, Amyloid beta-Protein Precursor, Mice, 0302 clinical medicine, metabolism [Amyloid beta-Protein Precursor], Amyloid precursor protein, Receptor, biology, Chemistry, Purinergic receptor, Inflammasome, Cell biology, Psychiatry and Mental health, genetics [Receptors, Purinergic P2X7], genetics [Amyloid beta-Protein Precursor], Cytokines, Cell activation, metabolism [Alzheimer Disease], medicine.drug, Mice, Transgenic, Neuroprotection, Article, 03 medical and health sciences, Cellular and Molecular Neuroscience, metabolism [Interleukin-1beta], Alzheimer Disease, NLR Family, Pyrin Domain-Containing 3 Protein, medicine, Animals, Humans, ddc:610, P2RX7 protein, human, Molecular Biology, metabolism [Cytokines], Disease Models, Animal, 030104 developmental biology, Synaptic plasticity, biology.protein, Receptors, Purinergic P2X7, metabolism [Inflammasomes], 030217 neurology & neurosurgery, Neuroscience

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d470686cb1fd57d884fafdbcb97cb35b
https://pubmed.ncbi.nlm.nih.gov/29934546

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4

Infiltrating monocytes promote brain inflammation and exacerbate neuronal damage after status epilepticus

المؤلفون: Richard M. Ransohoff, Andrea Bosch, Richard J. Miller, Nicholas H. Varvel, Raymond Dingledine, Jonas J. Neher, Wenyi Wang

المصدر: Proceedings of the National Academy of Sciences of the United States of America 113(38), E5665-E5674 (2016). doi:10.1073/pnas.1604263113

مصطلحات موضوعية: metabolism [Receptors, CCR2], 0301 basic medicine, CCR2, Chemokine, Interleukin-1beta, metabolism [Gliosis], genetics [Interleukin-1beta], immunology [Blood-Brain Barrier], Monocytes, Chemokine receptor, Mice, 0302 clinical medicine, Status Epilepticus, Ccl2 protein, mouse, pathology [Neurons], Gliosis, pathology [Encephalitis], Chemokine CCL2, Mice, Knockout, Neurons, Multidisciplinary, Microglia, metabolism [Chemokine CCL2], pathology [Gliosis], genetics [Chemokine CCL2], Ccr2 protein, mouse, metabolism [Status Epilepticus], medicine.anatomical_structure, PNAS Plus, Blood-Brain Barrier, pathology [Status Epilepticus], Encephalitis, ddc:500, Receptors, CCR2, metabolism [Seizures], Biology, CCL2, immunology [Seizures], Proinflammatory cytokine, genetics [Receptors, CCR2], 03 medical and health sciences, metabolism [Interleukin-1beta], Seizures, medicine, Animals, immunology [Encephalitis], Neuroinflammation, pathology [Monocytes], pathology [Seizures], Monocyte, pathology [Blood-Brain Barrier], genetics [Seizures], Immunity, Innate, genetics [Immunity, Innate], immunology [Gliosis], 030104 developmental biology, Immunology, biology.protein, metabolism [Encephalitis], immunology [Status Epilepticus], immunology [Neurons], 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03449b346856e0ff314d386d0367a59b
https://pubmed.ncbi.nlm.nih.gov/27601660

5

Polymorphisms in Inflammasome' Genes and Susceptibility to HIV-1 Infection

المؤلفون: Anselmo Jiro Kamada, Telma Miyuki Oshiro, Alberto José da Silva Duarte, Sergio Crovella, Alessandra Pontillo, Martina Girardelli

المساهمون: Pontillo, Alessandra, T. M., Oshiro, Girardelli, Martina, A. J., Kamada, Crovella, Sergio, A. J., S.

المصدر: JAIDS Journal of Acquired Immune Deficiency Syndromes. 59:121-125

مصطلحات موضوعية: Male, genetics, Caspase 1, Inflammasomes, Interleukin-1beta, genetics, Adult, Apoptosis Regulatory Protein, HIV Infections, Pathogenesis, Gene Frequency, NLRC4, genetics, Interleukin-1beta, genetics, Pharmacology (medical), Genetics, NLRP1, Caspase 1, Intracellular Signaling Peptides and Proteins, genetics, Female, Gene Frequency, Genetic Predisposition to Disease, Genotype, HIV Infection, Adaptor Proteins, virus diseases, Inflammasome, Single Nucleotide, Middle Aged, genetics, Brazil, CARD Signaling Adaptor Protein, Neoplasm Proteins, Infectious Diseases, Female, medicine.symptom, Brazil, medicine.drug, Adult, Genotype, NLR Proteins, genetics, Polymorphism, Single-nucleotide polymorphism, Inflammation, Biology, Polymorphism, Single Nucleotide, genetics, Carrier Protein, genetics, Male, Middle Aged, Neoplasm Protein, genetics, Intracellular Signaling Peptides and Protein, NLR Family, Pyrin Domain-Containing 3 Protein, medicine, Humans, Genetic Predisposition to Disease, Polymorphism, genetics, Calcium-Binding Protein, Gene, Adaptor Proteins, Signal Transducing, Innate immune system, Calcium-Binding Proteins, Signal Transducing, genetics, HIV-1, Humans, Inflammasome, CARD Signaling Adaptor Proteins, genetics, Adult, Apoptosis Regulatory Proteins, genetics, Brazil, CARD Signaling Adaptor Proteins, genetics, Calcium-Binding Proteins, genetics, Carrier Proteins, genetics, Female, Gene Frequency, Genetic Predisposition to Disease, Genotype, HIV Infections, genetics, HIV-1, Humans, Inflammasomes, genetics, Intracellular Signaling Peptides and Proteins, genetics, Male, Middle Aged, Neoplasm Proteins, Adaptor Protein, Immunology, HIV-1, Apoptosis Regulatory Proteins, Carrier Proteins

وصف الملف: STAMPA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c11610794e55a268a9283a3cc19e3a0
https://doi.org/10.1097/qai.0b013e3182392ebe

6

X-ray laser-induced ablation of lead compounds

المصدر: Proceedings of SPIE 8077, 807718-1 (2011). doi:10.1117/12.890134

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f074fb472d31d71062e6b31ebaedcd
https://bib-pubdb1.desy.de/record/140762

7

Phosphor materials under high-density XUV FEL excitation: mechanisms of luminescence quenching

المؤلفون: Vielhauer, S., Babin, V., de Grazia, M., Feldbach, E., Kirm, M., Nagirnyi, V., Vasilev, A., Juha, L., Bajt, S., Sobierajski, R.

المصدر: Proceedings of SPIE 7361, 73610R-1-73610R-9 (2009). doi:10.1117/12.822292
Damage to VUV, EUV, and X-Ray Optics II (Proceedings Volume )
Damage to VUV, EUV, and X-Ray Optics II (Proceedings Volume )SPIE Europe Optics and Optoelectronics, Prague, Czech Republic, 2009-04-20-2009-04-23

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894687649b91fdaab543146d307590c5
https://doi.org/10.1117/12.822292

8

Short-wavelength ablation of molecular solids: pulse duration and wavelength effects

المصدر: Journal of micro/nanolithography, MEMS and MOEMS 4, 033007 (2005). doi:10.1117/1.2037467

مصطلحات موضوعية: Adult, Male, Materials science, medicine.medical_treatment, Interleukin-1beta, genetics [Interleukin-1beta], complications [Hepatitis B, Chronic], law.invention, Optics, law, medicine, Humans, Electrical and Electronic Engineering, genetics [Tumor Necrosis Factor-alpha], Polymorphism, Genetic, Laser ablation, complications [Liver Cirrhosis], Tumor Necrosis Factor-alpha, business.industry, Mechanical Engineering, Pulse duration, genetics [Interleukin 1 Receptor Antagonist Protein], IL1RN protein, human, Nanosecond, Condensed Matter Physics, Laser, Ablation, genetics [Interleukin-10], Atomic and Molecular Physics, and Optics, Interleukin-10, Electronic, Optical and Magnetic Materials, Interleukin 1 Receptor Antagonist Protein, Wavelength, Femtosecond, genetics [Liver Cirrhosis], Optoelectronics, Female, ddc:620, business, Bandwidth-limited pulse

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::285d0ab5829077b5d0fc02f876ce4015
https://doi.org/10.1117/1.2037467

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