المؤلفون: Peng SY; Department of Medical Research, Taipei Veterans General Hospital, Taipei 11217, Taiwan, ROC., Chen CY; Department of Medical Research, Taipei Veterans General Hospital, Taipei 11217, Taiwan, ROC., Chen H; Department of Medical Research, Taipei Veterans General Hospital, Taipei 11217, Taiwan, ROC; Institute of Molecular Medicine, National Tsing Hua University, Hsinchu 300044, Taiwan, ROC., Yang YP; Department of Medical Research, Taipei Veterans General Hospital, Taipei 11217, Taiwan, ROC; Institute of Food Safety and Health Risk Assessment, School of Pharmaceutical Sciences, National Yang-Ming Chiao Tung University, Taipei 11221, Taiwan, ROC., Wang ML; Department of Medical Research, Taipei Veterans General Hospital, Taipei 11217, Taiwan, ROC; Institute of Food Safety and Health Risk Assessment, School of Pharmaceutical Sciences, National Yang-Ming Chiao Tung University, Taipei 11221, Taiwan, ROC., Tsai FT; Department of Medical Research, Taipei Veterans General Hospital, Taipei 11217, Taiwan, ROC., Chien CS; Institute of Physiology, National Yang Ming Chiao Tung University, Taiwan, ROC., Weng PY; Department of Medical Research, Taipei Veterans General Hospital, Taipei 11217, Taiwan, ROC., Tsai ET; Department of Medical Research, Taipei Veterans General Hospital, Taipei 11217, Taiwan, ROC., Wang IC; Department of Medical Research, Taipei Veterans General Hospital, Taipei 11217, Taiwan, ROC., Hsu CC; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei 112201, Taiwan, ROC., Lin TC; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei 112201, Taiwan, ROC., Hwang DK; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei 112201, Taiwan, ROC., Chen SJ; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei 112201, Taiwan, ROC., Chiou SH; Department of Medical Research, Taipei Veterans General Hospital, Taipei 11217, Taiwan, ROC; Institute of Pharmacology, School of Medicine, National Yang Ming Chiao Tung University, Taipei 11221, Taiwan, ROC; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei 112201, Taiwan, ROC; Genomics Research Center, Academia Sinica, Taipei 11529, Taiwan, ROC. Electronic address: shchiou@vghtpe.gov.tw., Chiao CC; Institute of Molecular Medicine, National Tsing Hua University, Hsinchu 300044, Taiwan, ROC. Electronic address: ccchiao@life.nthu.edu.tw., Chien Y; Department of Medical Research, Taipei Veterans General Hospital, Taipei 11217, Taiwan, ROC. Electronic address: g39005005@gmail.com.

المصدر: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Sep; Vol. 178, pp. 117270. Date of Electronic Publication: 2024 Aug 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE

مواضيع طبية MeSH: Optic Atrophy, Hereditary, Leber*/metabolism , Optic Atrophy, Hereditary, Leber*/pathology , Optic Atrophy, Hereditary, Leber*/genetics , Induced Pluripotent Stem Cells*/drug effects , Induced Pluripotent Stem Cells*/metabolism , Human Umbilical Vein Endothelial Cells*/metabolism , Human Umbilical Vein Endothelial Cells*/drug effects , Retinal Ganglion Cells*/metabolism , Retinal Ganglion Cells*/drug effects , Retinal Ganglion Cells*/pathology, Humans ; Mitochondria/drug effects ; Mitochondria/metabolism ; Phenotype ; Reactive Oxygen Species/metabolism ; Rotenone/pharmacology ; Culture Media, Conditioned/pharmacology ; Apoptosis/drug effects ; Electron Transport Complex I/metabolism ; Membrane Potential, Mitochondrial/drug effects ; Neovascularization, Pathologic/metabolism ; Angiogenesis

المؤلفون: Hu Q; Department of Epidemiology, Institute of Military Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing, 400038, P. R. China., Li C; Department of Epidemiology, Institute of Military Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing, 400038, P. R. China., Zhang T; Research Center for Nutrition and Food Safety, Institute of Military Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing, 400038, P. R. China., Yi L; Research Center for Nutrition and Food Safety, Institute of Military Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing, 400038, P. R. China., Shan Y; Department of Epidemiology, Institute of Military Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing, 400038, P. R. China., Ma X; Department of Epidemiology, Institute of Military Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing, 400038, P. R. China., Cai T; Department of Epidemiology, Institute of Military Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing, 400038, P. R. China., Ran L; Research Center for Nutrition and Food Safety, Institute of Military Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing, 400038, P. R. China., Shen H; Research Center for Nutrition and Food Safety, Institute of Military Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing, 400038, P. R. China., Li Y; Department of Epidemiology, Institute of Military Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing, 400038, P. R. China. liyafei2008@hotmail.com.

المصدر: Lipids in health and disease [Lipids Health Dis] 2024 Sep 03; Vol. 23 (1), pp. 279. Date of Electronic Publication: 2024 Sep 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101147696 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-511X (Electronic) Linking ISSN: 1476511X NLM ISO Abbreviation: Lipids Health Dis Subsets: MEDLINE

مواضيع طبية MeSH: NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism , Mitophagy*/drug effects , Flavonols*/pharmacology , Atherosclerosis*/drug therapy , Atherosclerosis*/prevention & control , Atherosclerosis*/pathology , Atherosclerosis*/metabolism , Inflammasomes*/metabolism , Inflammasomes*/drug effects , Human Umbilical Vein Endothelial Cells*/drug effects , Human Umbilical Vein Endothelial Cells*/metabolism , Diet, High-Fat*/adverse effects, Animals ; Mice ; Humans ; Male ; Mice, Inbred C57BL ; Interleukin-1beta/metabolism ; Interleukin-1beta/genetics ; Mitochondria/drug effects ; Mitochondria/metabolism

المؤلفون: Evanoff NG; School of Kinesiology, University of Minnesota, Minneapolis, Minnesota, USA.; Center for Pediatric Obesity Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, USA., Dengel DR; School of Kinesiology, University of Minnesota, Minneapolis, Minnesota, USA.; Center for Pediatric Obesity Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, USA., Stockelman KA; Department of Integrative Physiology, University of Colorado, Boulder, Colorado, USA., Fandl H; Department of Integrative Physiology, University of Colorado, Boulder, Colorado, USA., DeSouza NM; Department of Integrative Physiology, University of Colorado, Boulder, Colorado, USA., Greiner JJ; Department of Integrative Physiology, University of Colorado, Boulder, Colorado, USA., Dufresne SR; Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota, USA., Kotlyar M; Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota, USA., Garcia VP; Department of Integrative Physiology, University of Colorado, Boulder, Colorado, USA.

المصدر: Experimental physiology [Exp Physiol] 2024 Sep; Vol. 109 (9), pp. 1593-1603. Date of Electronic Publication: 2024 Aug 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 9002940 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-445X (Electronic) Linking ISSN: 09580670 NLM ISO Abbreviation: Exp Physiol Subsets: MEDLINE

مواضيع طبية MeSH: Nitric Oxide*/metabolism , Human Umbilical Vein Endothelial Cells*/metabolism , Human Umbilical Vein Endothelial Cells*/drug effects , Cell-Derived Microparticles*/metabolism , Nitric Oxide Synthase Type III*/metabolism , Electronic Nicotine Delivery Systems* , Inflammation*/metabolism , NF-kappa B*/metabolism, Humans ; Male ; Female ; Young Adult ; Vaping/adverse effects ; Vaping/metabolism ; Adult ; Interleukin-6/metabolism ; Cytokines/metabolism ; Interleukin-8/metabolism ; Cells, Cultured ; Phosphorylation

المؤلفون: Chen D; Dalian University of Technology, China; Dalian University of Technology Affiliated Central Hospital, China., Wang L; Dalian University of Technology, China., Jiang T; Dalian University of Technology Affiliated Central Hospital, China., Huang J; Dalian University of Technology Affiliated Central Hospital, China., Li M; Dalian University of Technology Affiliated Central Hospital, China., Zhang H; Dalian University of Technology Affiliated Central Hospital, China; Dalian Medical University, China. Electronic address: zhrr8080@163.com., Wang X; Dalian University of Technology Affiliated Central Hospital, China. Electronic address: dr.wangxianwei@163.com.

المصدر: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2024 Sep; Vol. 33 (9), pp. 107851. Date of Electronic Publication: 2024 Jul 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Saunders Country of Publication: United States NLM ID: 9111633 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8511 (Electronic) Linking ISSN: 10523057 NLM ISO Abbreviation: J Stroke Cerebrovasc Dis Subsets: MEDLINE

مواضيع طبية MeSH: Endoplasmic Reticulum Chaperone BiP* , Transcription Factor CHOP*/metabolism , Transcription Factor CHOP*/genetics , Heat-Shock Proteins*/metabolism , Heat-Shock Proteins*/genetics , Human Umbilical Vein Endothelial Cells*/metabolism , Plaque, Atherosclerotic*, Humans ; Male ; Aged ; Stress, Mechanical ; Female ; Middle Aged ; Cells, Cultured ; Carotid Artery Diseases/metabolism ; Carotid Artery Diseases/surgery ; Carotid Artery Diseases/physiopathology ; Carotid Artery Diseases/genetics ; Carotid Artery Diseases/pathology ; Carotid Stenosis/physiopathology ; Carotid Stenosis/metabolism ; RNA, Messenger/metabolism

المؤلفون: Zieliński A; Section of Surgery, Vascular Surgery and Phlebology, doktorA Medical Center, Warsaw, Poland., Jasińska-Sumińska K; Department of Pathophysiology, Poznan University of Medical Sciences, Poznań, Poland., Bręborowicz A; Department of Pathophysiology, Poznan University of Medical Sciences, Poznań, Poland; Department of Anatomy and Histology, University of Zielona Góra, Zielona Góra, Poland., Kowalska K; Department of Histology and Embryology, Poznan University of Medical Sciences, Poznań, Poland., Zabel M; Department of Anatomy and Histology, University of Zielona Góra, Zielona Góra, Poland., Wysocka T; Department of Anatomy and Histology, University of Zielona Góra, Zielona Góra, Poland., Khalil RA; Vascular Surgery Research Laboratories, Division of Vascular and Endovascular Surgery, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA., Raffetto JD; VA Boston Healthcare System, Harvard Medical School, Brigham and Women's Hospital, Boston, MA., Urbanek T; Department of General Surgery, Vascular Surgery, Angiology and Phlebology, Medical University of Silesia, Katowice, Poland. Electronic address: urbanek.tom@interia.pl.

المصدر: Journal of vascular surgery. Venous and lymphatic disorders [J Vasc Surg Venous Lymphat Disord] 2024 Sep; Vol. 12 (5), pp. 101941. Date of Electronic Publication: 2024 Jun 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101607771 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-3348 (Electronic) NLM ISO Abbreviation: J Vasc Surg Venous Lymphat Disord Subsets: MEDLINE

مواضيع طبية MeSH: Glycosaminoglycans*/blood , Glycosaminoglycans*/therapeutic use , Venous Insufficiency*/drug therapy , Venous Insufficiency*/blood , Vascular Cell Adhesion Molecule-1*/blood , Human Umbilical Vein Endothelial Cells*/drug effects , Human Umbilical Vein Endothelial Cells*/metabolism , Matrix Metalloproteinase 9*/blood, Humans ; Male ; Female ; Chronic Disease ; Middle Aged ; Biomarkers/blood ; Treatment Outcome ; Cells, Cultured ; Saphenous Vein/drug effects ; Aged ; von Willebrand Factor/metabolism ; Inflammation Mediators/blood ; Adult ; Interleukin-6/blood

المؤلفون: Hollis WC; Center for Biologics Evaluation and Research, FDA, Silver Spring, MD, USA., Farooq S; Center for Biologics Evaluation and Research, FDA, Silver Spring, MD, USA., Khoshi MR; Center for Biologics Evaluation and Research, FDA, Silver Spring, MD, USA., Patel M; Center for Biologics Evaluation and Research, FDA, Silver Spring, MD, USA.; Center for Devices and Radiological Health, FDA, Silver Spring, MD, USA., Karnaukhova E; Center for Biologics Evaluation and Research, FDA, Silver Spring, MD, USA., Eller N; Center for Biologics Evaluation and Research, FDA, Silver Spring, MD, USA., Holada K; Institute of Immunology and Microbiology, First Faculty of Medicine, Charles University, Prague, Czech Republic., Scott DE; Center for Biologics Evaluation and Research, FDA, Silver Spring, MD, USA., Simak J; Center for Biologics Evaluation and Research, FDA, Silver Spring, MD, USA. jan.simak@fda.hhs.gov.; Laboratory of Cellular Hematology, Division of Blood Components and Devices, Center for Biologics Evaluation and Research, Food and Drug Administration, OBRR, 10903 New Hampshire Avenue, WO Bldg. 52/72, Rm. 4210, Silver Spring, MD, USA. jan.simak@fda.hhs.gov.

المصدر: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2024 Aug 30; Vol. 81 (1), pp. 376. Date of Electronic Publication: 2024 Aug 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE

مواضيع طبية MeSH: Tumor Necrosis Factor-alpha*/metabolism , Human Umbilical Vein Endothelial Cells*/drug effects , Human Umbilical Vein Endothelial Cells*/metabolism , Autophagy*/drug effects , Receptors, IgG*/metabolism , Immunoglobulins, Intravenous*, Humans ; Particle Size ; Silicon Dioxide/chemistry ; Silicon Dioxide/toxicity ; Apoptosis/drug effects ; Intercellular Adhesion Molecule-1/metabolism ; Cell Survival/drug effects ; Protein Corona/metabolism ; TOR Serine-Threonine Kinases/metabolism

المؤلفون: Lee MY; Department and Research Institute of Dental Biomaterials and Bioengineering, Yonsei University College of Dentistry, Seoul, Republic of Korea., Yoon HW; Department of Conservative Dentistry and Oral Science Research Center, Gangnam Severance Hospital, Yonsei University College of Dentistry, Seoul, Republic of Korea., Kim SI; Department of Conservative Dentistry and Oral Science Research Center, College of Dentistry, Yonsei University, Seoul, Republic of Korea., Kwon JS; Department and Research Institute of Dental Biomaterials and Bioengineering, Yonsei University College of Dentistry, Seoul, Republic of Korea.; BK21 FOUR Project, Yonsei University College of Dentistry, Seoul, Republic of Korea., Shin SJ; Department of Conservative Dentistry and Oral Science Research Center, Gangnam Severance Hospital, Yonsei University College of Dentistry, Seoul, Republic of Korea.

المصدر: Biofabrication [Biofabrication] 2024 Aug 21; Vol. 16 (4). Date of Electronic Publication: 2024 Aug 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: IOP Pub Country of Publication: England NLM ID: 101521964 Publication Model: Electronic Cited Medium: Internet ISSN: 1758-5090 (Electronic) Linking ISSN: 17585082 NLM ISO Abbreviation: Biofabrication Subsets: MEDLINE

مواضيع طبية MeSH: Dental Pulp*/cytology , Human Umbilical Vein Endothelial Cells*, Humans ; Dental Pulp Capping ; Lab-On-A-Chip Devices ; Stem Cells/cytology ; Stem Cells/metabolism ; Pulp Capping and Pulpectomy Agents/chemistry ; Pulp Capping and Pulpectomy Agents/pharmacology ; Dura Mater

المؤلفون: Gao Y; Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, 430060, China., Mao J; Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, 430060, China., Zhang R; Center of Regenerative Medicine & Department of Stomatology, Renmin Hospital of Wuhan University, Wuhan, 430060, China., Deng Q; Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, 430060, China., Wang Y; Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, 430060, China., Pan Y; Aier Eye Hospital of Wuhan University, Wuhan, Hubei, 430063, China., Liudi S; Department of Cardiology, Renmin Hospital of Wuhan University, Cardiovascular Research Institute of Wuhan University, Hubei Key Laboratory of Cardiology, Wuhan, Hubei, 430063, China., Wang Y; Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, 430060, China., Fan X; Cancer Center, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430063, China., Yang Y; Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, 430060, China. Electronic address: ophyangyanning@gmail.com., Wan S; Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, 430060, China. Electronic address: ophwss@whu.edu.cn.

المصدر: European journal of pharmacology [Eur J Pharmacol] 2024 Aug 15; Vol. 977, pp. 176673. Date of Electronic Publication: 2024 May 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Protein-Arginine N-Methyltransferases*/metabolism , Protein-Arginine N-Methyltransferases*/antagonists & inhibitors , Protein-Arginine N-Methyltransferases*/genetics , Fibroblast Growth Factor 2*/metabolism , Macrophages*/drug effects , Macrophages*/metabolism , Proto-Oncogene Proteins c-akt*/metabolism , Signal Transduction*/drug effects , Phosphatidylinositol 3-Kinases*/metabolism , Corneal Neovascularization*/pathology , Corneal Neovascularization*/metabolism , Corneal Neovascularization*/prevention & control , Human Umbilical Vein Endothelial Cells*/drug effects , Human Umbilical Vein Endothelial Cells*/metabolism, Animals ; Mice ; Humans ; RAW 264.7 Cells ; Male ; Mice, Inbred C57BL ; Disease Models, Animal ; Repressor Proteins

المؤلفون: Kooshari A; Department of Hematology and Blood Banking, Faculty of Allied Medicine, Iran University of Medical Sciences, Hemmat Highway, Tehran, 14155-5983, Iran., Shahriyary F; Department of Hematology and Blood Banking, Faculty of Allied Medicine, Iran University of Medical Sciences, Hemmat Highway, Tehran, 14155-5983, Iran., Shahidi M; Department of Hematology and Blood Banking, Faculty of Allied Medicine, Iran University of Medical Sciences, Hemmat Highway, Tehran, 14155-5983, Iran. Shahidi.m@iums.ac.ir., Vafajoo M; Department of Hematology and Blood Banking, Faculty of Allied Medicine, Iran University of Medical Sciences, Hemmat Highway, Tehran, 14155-5983, Iran., Amirzargar MR; Department of Hematology and Blood Banking, Faculty of Allied Medicine, Iran University of Medical Sciences, Hemmat Highway, Tehran, 14155-5983, Iran.

المصدر: Medical oncology (Northwood, London, England) [Med Oncol] 2024 Aug 05; Vol. 41 (9), pp. 217. Date of Electronic Publication: 2024 Aug 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 9435512 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-131X (Electronic) Linking ISSN: 13570560 NLM ISO Abbreviation: Med Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Human Umbilical Vein Endothelial Cells*/drug effects , Human Umbilical Vein Endothelial Cells*/metabolism , Multiple Myeloma*/pathology , Multiple Myeloma*/drug therapy , Multiple Myeloma*/metabolism , Extracellular Vesicles*/metabolism , Extracellular Vesicles*/drug effects , Neovascularization, Pathologic*/drug therapy , Neovascularization, Pathologic*/pathology , Neovascularization, Pathologic*/metabolism , Tetrahydroisoquinolines*/pharmacology , Cell Movement*/drug effects, Humans ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Coculture Techniques ; Angiogenesis Inhibitors/pharmacology ; Angiogenesis

المؤلفون: Ni JR; Department of Orthopedics, Jiangsu Province (Suqian) Hospital, Suqian, China., Zhang QH; Department of Orthopedics, Jiangsu Province (Suqian) Hospital, Suqian, China., Deng JL; Department of Orthopedics, Jiangsu Province (Suqian) Hospital, Suqian, China., Wang HH; Department of Orthopedics, Jiangsu Province (Suqian) Hospital, Suqian, China., Duan YC; Department of Orthopedics, Jiangsu Province (Suqian) Hospital, Suqian, China., Zhang CJ; Department of Orthopedics, Jiangsu Province (Suqian) Hospital, Suqian, China., Jiang LT; Department of Orthopedics, Jiangsu Province (Suqian) Hospital, Suqian, China.

المصدر: Chemical biology & drug design [Chem Biol Drug Des] 2024 Aug; Vol. 104 (2), pp. e14602.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print Cited Medium: Internet ISSN: 1747-0285 (Electronic) Linking ISSN: 17470277 NLM ISO Abbreviation: Chem Biol Drug Des Subsets: MEDLINE

مواضيع طبية MeSH: Iridoid Glucosides*/pharmacology , Human Umbilical Vein Endothelial Cells*/drug effects , Human Umbilical Vein Endothelial Cells*/metabolism , Network Pharmacology*, Humans ; Cell Survival/drug effects ; Protein Interaction Maps/drug effects ; ErbB Receptors/metabolism ; ErbB Receptors/genetics ; Signal Transduction/drug effects ; Neovascularization, Physiologic/drug effects ; Cell Movement/drug effects ; Angiogenesis