المؤلفون: Kumari, Anni, Grønnemose, Anne, Kristensen, Kristian, Winther, Anne-Marie, Jørgensen, Thomas, Ploug, Michael, Young, Stephen

المصدر: Proceedings of the National Academy of Sciences of USA. 120(18)

مصطلحات موضوعية: ANGPTL4, APOC2, GPIHBP1, HDX-MS, intravascular lipolysis, Lipoprotein Lipase, Angiopoietin-Like Protein 4, Apolipoprotein C-II, Protein Domains, Catalytic Domain, Triglycerides

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4j59132m

المؤلفون: Song, Wenxin, Yang, Ye, Heizer, Patrick, Tu, Yiping, Weston, Thomas, Kim, Joonyoung, Munguia, Priscilla, Jung, Hyesoo, Fong, Jared, Tran, Caitlyn, Ploug, Michael, Beigneux, Anne, Fong, Loren, Young, Stephen

المصدر: Proceedings of the National Academy of Sciences of USA. 120(8)

مصطلحات موضوعية: ANGPTL4, brown adipose tissue, intravascular lipolysis, thermoneutral, triglyceride hydrolysis, Animals, Mice, Adipose Tissue, Adipose Tissue, Brown, Antibodies, Lipoprotein Lipase, Receptors, Lipoprotein, Temperature, Triglycerides

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9kw4v0cj

المؤلفون: Leth-Espensen, Katrine Z, Kristensen, Kristian K, Kumari, Anni, Winther, Anne-Marie L, Young, Stephen G, Jørgensen, Thomas JD, Ploug, Michael

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 118(12)

مصطلحات موضوعية: Analytical Chemistry, Biochemistry and Cell Biology, Chemical Sciences, Biological Sciences, Amino Acid Sequence, Angiopoietin-Like Protein 4, Binding Sites, Catalysis, Catalytic Domain, Disease Susceptibility, Humans, Hydrolases, Kinetics, Lipolysis, Lipoprotein Lipase, Mass Spectrometry, Protein Binding, Protein Domains, Protein Stability, Protein Unfolding, Temperature, intrinsic disorder, HDX-MS, intravascular lipolysis, GPIHBP1, hypertriglyceridemia

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4mf3p7tf

المؤلفون: Kristensen, Kristian K, Leth-Espensen, Katrine Zinck, Mertens, Haydyn DT, Birrane, Gabriel, Meiyappan, Muthuraman, Olivecrona, Gunilla, Jørgensen, Thomas JD, Young, Stephen G, Ploug, Michael

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 117(8)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Amino Acid Motifs, Angiopoietin-Like Protein 4, Animals, Antibodies, Monoclonal, Dimerization, Humans, Hypertriglyceridemia, Lipoprotein Lipase, Protein Unfolding, Receptors, Lipoprotein, Triglycerides, HDX-MS, intravascular lipolysis, lipoprotein lipase, GPIHBP1, surface plasmon resonance

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/22x1k0xt

المؤلفون: Kristensen, Kristian K, Midtgaard, Søren Roi, Mysling, Simon, Kovrov, Oleg, Hansen, Lars Bo, Skar-Gislinge, Nicholas, Beigneux, Anne P, Kragelund, Birthe B, Olivecrona, Gunilla, Young, Stephen G, Jørgensen, Thomas JD, Fong, Loren G, Ploug, Michael

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 115(26)

مصطلحات موضوعية: Aetiology, 2.1 Biological and endogenous factors, Angiopoietin-Like Protein 4, Animals, Endothelial Cells, Humans, Hyperlipoproteinemia Type I, Lipoprotein Lipase, Mice, Protein Binding, Protein Domains, Receptors, Lipoprotein, Tyrosine, hypertriglyceridemia, electrostatic steering, intrinsically disordered region, intravascular lipolysis, autoimmune disease

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4sx8r12w

المؤلفون: Hu, Xuchen, Dallinga-Thie, Geesje M, Hovingh, G Kees, Chang, Sandy Y, Sandoval, Norma P, Dang, Tiffany Ly P, Fukamachi, Isamu, Miyashita, Kazuya, Nakajima, Katsuyuki, Murakami, Masami, Fong, Loren G, Ploug, Michael, Young, Stephen G, Beigneux, Anne P

المصدر: Journal of Clinical Lipidology. 11(4)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Autoimmune Disease, 2.1 Biological and endogenous factors, Aetiology, Adult, Animals, Autoantibodies, Cell Line, Humans, Hyperlipoproteinemia Type I, Hypertriglyceridemia, Male, Mutation, Receptors, Lipoprotein, Chylomicrons, Endothelial cells, Intravascular lipolysis, Lipids, Triglycerides, Medical Biochemistry and Metabolomics, Cardiorespiratory Medicine and Haematology, Cardiovascular System & Hematology, Cardiovascular medicine and haematology, Medical biochemistry and metabolomics

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2fx2w4ws

المؤلفون: Kristian Kølby Kristensen, Katrine Zinck Leth-Espensen, Anni Kumari, Anne Louise Grønnemose, Anne-Marie Lund-Winther, Stephen G. Young, Michael Ploug

المصدر: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

مصطلحات موضوعية: GPIHBP1, lipoprotein lipase, intravascular lipolysis, intrinsic disorder, ANGPTL4, LU domain, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2021.702508/full; https://doaj.org/toc/2296-634X

URL الوصول: https://doaj.org/article/90d2661935c3460c90812ea384db77fa

المؤلفون: Wenxin Song, Ye Yang, Patrick Heizer, Yiping Tu, Thomas A. Weston, Joonyoung R. Kim, Priscilla Munguia, Hyesoo Jung, Jared L.-C. Fong, Caitlyn Tran, Michael Ploug, Anne P. Beigneux, Stephen G. Young, Loren G. Fong

المصدر: Song, W, Yang, Y, Heizer, P, Tu, Y, Weston, T A, Kim, J R, Munguia, P, Jung, H, Fong, J L C, Tran, C, Ploug, M, Beigneux, A P, Young, S G & Fong, L G 2023, ' Intracapillary LPL levels in brown adipose tissue, visualized with an antibody-based approach, are regulated by ANGPTL4 at thermoneutral temperatures ', Proceedings of the National Academy of Sciences of the United States of America, vol. 120, no. 8, e2219833120 . https://doi.org/10.1073/pnas.2219833120

مصطلحات موضوعية: thermoneutral, ANGPTL4, Multidisciplinary, brown adipose tissue, triglyceride hydrolysis, intravascular lipolysis

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ee0bd61ac352612dab52cbff6fb337f
https://doi.org/10.1073/pnas.2219833120

المؤلفون: Anni Kumari, Anne-Marie Lund Winther, Thomas J. D. Jørgensen, Katrine Zinck Leth-Espensen, Michael Ploug, Kristian Kølby Kristensen, Stephen G. Young

المصدر: Leth-Espensen, K Z, Kristensen, K K, Kumari, A, Winther, A M L, Young, S G, Jørgensen, T J D & Ploug, M 2021, ' The intrinsic instability of the hydrolase domain of lipoprotein lipase facilitates its inactivation by ANGPTL4-catalyzed unfolding ', Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 12, e2026650118 . https://doi.org/10.1073/pnas.2026650118
The Proceedings of the National Academy of Sciences
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 12

مصطلحات موضوعية: 0301 basic medicine, Intrinsic disorder | HDX-MS | intravascular lipolysis | GPIHBP1 | hypertriglyceridemia, Hydrolases, hypertriglyceridemia, Lipolysis, Allosteric regulation, Context (language use), 030204 cardiovascular system & hematology, Catalysis, Mass Spectrometry, 03 medical and health sciences, 0302 clinical medicine, Protein Domains, ANGPTL4, Catalytic Domain, Hydrolase, Angiopoietin-Like Protein 4, Humans, Amino Acid Sequence, HDX-MS, Receptor, Protein Unfolding, Lipoprotein lipase, Multidisciplinary, Binding Sites, GPIHBP1, Chemistry, Protein Stability, intrinsic disorder, digestive, oral, and skin physiology, Temperature, nutritional and metabolic diseases, Lipid metabolism, Biological Sciences, intravascular lipolysis, Kinetics, Lipoprotein Lipase, 030104 developmental biology, Biophysics, lipids (amino acids, peptides, and proteins), Disease Susceptibility, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f92aa963c884763285605942810561
https://portal.findresearcher.sdu.dk/da/publications/b1376d32-830d-49cd-9350-20e20ce2d46e

المؤلفون: Ménard, Sébastien L., Ci, Xiuli, Frisch, Frédérique, Normand-Lauzière, François, Cadorette, Jules, Ouellet, René, Van Lier, Johannes E., Bénard, François, Bentourkia, M’hamed, Lecomte, Roger, Carpentier, André C.

المصدر: Molecular Imaging and Biology. January 2009 11(1):6-14