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1دورية أكاديمية
المؤلفون: Revercomb L; Department of Otolaryngology-Head and Neck Surgery, Rutgers New Jersey Medical School, Newark, NJ, USA., Patel AM; Department of Otolaryngology-Head and Neck Surgery, Rutgers New Jersey Medical School, Newark, NJ, USA., Filimonov I; Department of Otolaryngology-Head and Neck Surgery, Rutgers New Jersey Medical School, Newark, NJ, USA., Lerner D; Department of Otolaryngology-Head and Neck Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Filimonov A; Department of Otolaryngology-Head and Neck Surgery, Rutgers New Jersey Medical School, Newark, NJ, USA.
المصدر: American journal of rhinology & allergy [Am J Rhinol Allergy] 2024 Sep; Vol. 38 (5), pp. 354-360. Date of Electronic Publication: 2024 Jun 07.
نوع المنشور: Journal Article; Review
بيانات الدورية: Publisher: SAGE Publications Country of Publication: United States NLM ID: 101490775 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1945-8932 (Electronic) Linking ISSN: 19458932 NLM ISO Abbreviation: Am J Rhinol Allergy Subsets: MEDLINE
مواضيع طبية MeSH: Fluorouracil*/administration & dosage , Fluorouracil*/therapeutic use , Adenocarcinoma*/drug therapy , Adenocarcinoma*/pathology , Paranasal Sinus Neoplasms*/drug therapy , Paranasal Sinus Neoplasms*/pathology , Paranasal Sinus Neoplasms*/mortality , Administration, Topical* , Papilloma, Inverted*/drug therapy , Papilloma, Inverted*/pathology, Humans ; Neoplasm Recurrence, Local/prevention & control ; Antimetabolites, Antineoplastic/administration & dosage ; Antimetabolites, Antineoplastic/therapeutic use ; Combined Modality Therapy ; Treatment Outcome
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2دورية أكاديمية
المؤلفون: Zi J; Department of Otorhinolaryngology Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China., Wei Z; Department of Otorhinolaryngology Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China., Wang L; Department of Otorhinolaryngology Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China., Yan X; Department of Otorhinolaryngology Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China., Zhang S; Department of Otorhinolaryngology Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China., Zhao L; Department of Otorhinolaryngology Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China., Li D; Department of Otorhinolaryngology Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China., Dong Z; Department of Otorhinolaryngology Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China., Yu L; Department of Otorhinolaryngology Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China., Jiang Y; Department of Otorhinolaryngology Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China.
المصدر: The Laryngoscope [Laryngoscope] 2024 Sep; Vol. 134 (9), pp. 3941-3946. Date of Electronic Publication: 2024 Mar 28.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 8607378 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-4995 (Electronic) Linking ISSN: 0023852X NLM ISO Abbreviation: Laryngoscope Subsets: MEDLINE
مواضيع طبية MeSH: Papilloma, Inverted*/genetics , Papilloma, Inverted*/pathology , Papilloma, Inverted*/metabolism , Autophagy*/genetics , HMGB1 Protein*/genetics , HMGB1 Protein*/metabolism , Paranasal Sinus Neoplasms*/genetics , Paranasal Sinus Neoplasms*/pathology , Paranasal Sinus Neoplasms*/metabolism , Autophagy-Related Protein 5*/genetics , Autophagy-Related Protein 5*/metabolism , Beclin-1*/genetics , Beclin-1*/metabolism, Humans ; Male ; Female ; Middle Aged ; Adult ; Aged ; Microtubule-Associated Proteins/genetics ; Microtubule-Associated Proteins/metabolism ; Neoplasm Staging ; Case-Control Studies ; Gene Expression Regulation, Neoplastic ; Clinical Relevance
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3دورية أكاديمية
المؤلفون: He S; Department of Otorhinolaryngology, Qilu Hospital of Shandong University, NHC Key Laboratory of Otorhinolaryngology (Shandong University), Jinan, China.; Department of Radiology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China., Zhao Y; Department of Radiology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China., Shi L; Department of Otorhinolaryngology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China., Yang X; Clinical Epidemiology Unit, Qilu Hospital of Shandong University, Jinan, China., Wang X; Department of Otorhinolaryngology, Weihai Municipal Hospital, Weihai, China., Luo Y; Department of Otorhinolaryngology, Qilu Hospital of Shandong University, NHC Key Laboratory of Otorhinolaryngology (Shandong University), Jinan, China., Wang M; Department of Otorhinolaryngology, Qilu Hospital of Shandong University, NHC Key Laboratory of Otorhinolaryngology (Shandong University), Jinan, China., Zhang X; Department of Otorhinolaryngology, Qilu Hospital of Shandong University, NHC Key Laboratory of Otorhinolaryngology (Shandong University), Jinan, China., Li X; Department of Otorhinolaryngology, Qilu Hospital of Shandong University, NHC Key Laboratory of Otorhinolaryngology (Shandong University), Jinan, China., Yu D; Department of Radiology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China., Feng X; Department of Otorhinolaryngology, Qilu Hospital of Shandong University, NHC Key Laboratory of Otorhinolaryngology (Shandong University), Jinan, China. drfengxin@sdu.edu.cn.
المصدر: Scientific reports [Sci Rep] 2024 Aug 20; Vol. 14 (1), pp. 19299. Date of Electronic Publication: 2024 Aug 20.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
مواضيع طبية MeSH: Nasal Polyps*/diagnostic imaging , Nasal Polyps*/pathology , Papilloma, Inverted*/diagnostic imaging , Papilloma, Inverted*/pathology , Radiomics* , Rhinosinusitis*/diagnostic imaging , Rhinosinusitis*/pathology , Tomography, X-Ray Computed*/methods, Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Chronic Disease ; Diagnosis, Differential ; Retrospective Studies
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4دورية أكاديمية
المؤلفون: Makihara S; Department of Otolaryngology-Head & Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences., Otani Y; Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences., Uraguchi K; Department of Otolaryngology-Head & Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences., Ono S; Department of Pathology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences., Shimizu A; Department of Otolaryngology-Head & Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences., Ikemachi R; Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences., Okazaki Y; Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences., Ota T; Department of Plastic and Reconstructive Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences., Matsumoto H; Department of Plastic and Reconstructive Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences., Miyamoto S; Department of Otolaryngology-Head & Neck Surgery, Kagawa Rosai Hospital., Tsumura M; Department of Otolaryngology-Head & Neck Surgery, Kagawa Rosai Hospital., Hayashi S; Department of Neurosurgery, Kagawa Rosai Hospital., Umakoshi M; Department of Neurosurgery, Kagawa Rosai Hospital., Hirashita K; Department of Neurosurgery, Kagawa Rosai Hospital., Ando M; Department of Otolaryngology-Head & Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.
المصدر: Acta medica Okayama [Acta Med Okayama] 2024 Aug; Vol. 78 (4), pp. 337-343.
نوع المنشور: Case Reports; Journal Article; Review
بيانات الدورية: Publisher: Okayama University Medical School Country of Publication: Japan NLM ID: 0417611 Publication Model: Print Cited Medium: Internet ISSN: 0386-300X (Print) Linking ISSN: 0386300X NLM ISO Abbreviation: Acta Med Okayama Subsets: MEDLINE
مواضيع طبية MeSH: Pneumocephalus*/diagnostic imaging , Pneumocephalus*/etiology , Pneumocephalus*/surgery , Papilloma, Inverted*/surgery , Papilloma, Inverted*/pathology , Papilloma, Inverted*/complications , Frontal Sinus*/pathology , Frontal Sinus*/diagnostic imaging , Frontal Sinus*/surgery , Paranasal Sinus Neoplasms*/surgery , Paranasal Sinus Neoplasms*/complications , Paranasal Sinus Neoplasms*/pathology , Paranasal Sinus Neoplasms*/diagnostic imaging , Ethmoid Sinus*/pathology , Ethmoid Sinus*/diagnostic imaging , Ethmoid Sinus*/surgery, Humans ; Male ; Aged
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5دورية أكاديمية
المؤلفون: Ren Y; Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, No. 1, Dongjiaominxiang, Dongcheng District, Beijing, 100730, China.; Beijing Laboratory of Allergic Diseases, Key Laboratory of Otolaryngology Head and Neck Surgery, Ministry of Education, Beijing Institute of Otolaryngology, Beijing Key Laboratory of Nasal Diseases, Capital Medical University, Beijing, 100005, China.; Research Unit of Diagnosis and Treatment of Chronic Nasal Diseases, Chinese Academy of Medical Sciences, Beijing, 100005, China., Fang G; Department of Otolaryngology Head and Neck Surgery, Beijing DiTan Hospital, Capital Medical University, Beijing, China., Wang K; Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, No. 1, Dongjiaominxiang, Dongcheng District, Beijing, 100730, China.; Research Unit of Diagnosis and Treatment of Chronic Nasal Diseases, Chinese Academy of Medical Sciences, Beijing, 100005, China., Yan B; Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, No. 1, Dongjiaominxiang, Dongcheng District, Beijing, 100730, China. ice_490@163.com.; Beijing Laboratory of Allergic Diseases, Key Laboratory of Otolaryngology Head and Neck Surgery, Ministry of Education, Beijing Institute of Otolaryngology, Beijing Key Laboratory of Nasal Diseases, Capital Medical University, Beijing, 100005, China. ice_490@163.com.; Research Unit of Diagnosis and Treatment of Chronic Nasal Diseases, Chinese Academy of Medical Sciences, Beijing, 100005, China. ice_490@163.com., Wang C; Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, No. 1, Dongjiaominxiang, Dongcheng District, Beijing, 100730, China. wangcs830@126.com.; Beijing Laboratory of Allergic Diseases, Key Laboratory of Otolaryngology Head and Neck Surgery, Ministry of Education, Beijing Institute of Otolaryngology, Beijing Key Laboratory of Nasal Diseases, Capital Medical University, Beijing, 100005, China. wangcs830@126.com.; Research Unit of Diagnosis and Treatment of Chronic Nasal Diseases, Chinese Academy of Medical Sciences, Beijing, 100005, China. wangcs830@126.com.
المصدر: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery [Eur Arch Otorhinolaryngol] 2024 Aug; Vol. 281 (8), pp. 4221-4230. Date of Electronic Publication: 2024 May 07.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Springer International Country of Publication: Germany NLM ID: 9002937 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1434-4726 (Electronic) Linking ISSN: 09374477 NLM ISO Abbreviation: Eur Arch Otorhinolaryngol Subsets: MEDLINE
مواضيع طبية MeSH: Papilloma, Inverted*/diagnosis , Papilloma, Inverted*/diagnostic imaging , Papilloma, Inverted*/pathology , Endoscopy*/methods , Paranasal Sinus Neoplasms*/diagnostic imaging , Paranasal Sinus Neoplasms*/diagnosis , Paranasal Sinus Neoplasms*/pathology, Humans ; Male ; Female ; Middle Aged ; Adult ; Aged ; Nomograms ; Image Enhancement/methods ; Retrospective Studies ; Diagnosis, Differential ; Nose Neoplasms/diagnosis ; Nose Neoplasms/diagnostic imaging ; Nose Neoplasms/pathology
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6دورية أكاديمية
المؤلفون: den Heijer MC; Department of Otorhinolaryngology - Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; Graduate School of Medical Sciences, University of Groningen, Groningen, The Netherlands., Joustra GE; Department of Otorhinolaryngology - Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; Graduate School of Medical Sciences, University of Groningen, Groningen, The Netherlands., Vermeulen KM; Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Korsten-Meijer AGW; Department of Otorhinolaryngology - Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Feijen RA; Department of Otorhinolaryngology - Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
المصدر: Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery [Clin Otolaryngol] 2024 Jul; Vol. 49 (4), pp. 453-461. Date of Electronic Publication: 2024 Apr 13.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 101247023 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1749-4486 (Electronic) Linking ISSN: 17494478 NLM ISO Abbreviation: Clin Otolaryngol Subsets: MEDLINE
مواضيع طبية MeSH: Quality of Life* , Papilloma, Inverted*/surgery , Papilloma, Inverted*/psychology , Paranasal Sinus Neoplasms*/surgery , Paranasal Sinus Neoplasms*/psychology, Humans ; Male ; Female ; Prospective Studies ; Middle Aged ; Aged ; Surveys and Questionnaires ; Endoscopy/methods ; Adult
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7دورية أكاديمية
المؤلفون: Xian M; Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China., Yu J; Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China., Li Z; Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China., Piao Y; Department of Pathology, Beijing Tongren Hospital, Capital Medical University, Beijing, China., Wang C; Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China.; Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China., Xian J; Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China., Zhang L; Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China.; Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China.
المصدر: International forum of allergy & rhinology [Int Forum Allergy Rhinol] 2024 Jul; Vol. 14 (7), pp. 1173-1181. Date of Electronic Publication: 2024 Jan 21.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Published for ARS-AAOA by Wiley-Blackwell Country of Publication: United States NLM ID: 101550261 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2042-6984 (Electronic) Linking ISSN: 20426976 NLM ISO Abbreviation: Int Forum Allergy Rhinol Subsets: MEDLINE
مواضيع طبية MeSH: Papilloma, Inverted*/diagnostic imaging , Papilloma, Inverted*/pathology , Magnetic Resonance Imaging* , Carcinoma, Squamous Cell*/diagnostic imaging , Carcinoma, Squamous Cell*/pathology , Microvessels*/diagnostic imaging , Microvessels*/pathology , Paranasal Sinus Neoplasms*/diagnostic imaging , Paranasal Sinus Neoplasms*/pathology , Contrast Media*, Humans ; Middle Aged ; Male ; Female ; Aged ; Neovascularization, Pathologic/diagnostic imaging ; Retrospective Studies ; Adult ; Nose Neoplasms/diagnostic imaging ; Nose Neoplasms/pathology
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8دورية أكاديمية
المؤلفون: Liang N; Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China., Qu J; Department of Otolaryngology, Beijing Huaxin Hospital, The First Affiliated Hospital of Tsinghua University, Beijing, China., Huang Q; Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China., Zhou B; Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China. entzhou@263.net.
المصدر: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery [Eur Arch Otorhinolaryngol] 2024 Sep; Vol. 281 (9), pp. 4763-4771. Date of Electronic Publication: 2024 Mar 25.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Springer International Country of Publication: Germany NLM ID: 9002937 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1434-4726 (Electronic) Linking ISSN: 09374477 NLM ISO Abbreviation: Eur Arch Otorhinolaryngol Subsets: MEDLINE
مواضيع طبية MeSH: Papilloma, Inverted*/surgery , Maxillary Sinus Neoplasms*/surgery , Endoscopy*/methods, Humans ; Female ; Male ; Middle Aged ; Retrospective Studies ; Adult ; Aged ; Aged, 80 and over ; Follow-Up Studies ; Treatment Outcome ; Maxillary Sinus/surgery ; Maxillary Sinus/diagnostic imaging ; Neoplasm Recurrence, Local/surgery
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9دورية أكاديمية
المؤلفون: Li F; Department of Otorhinolaryngology,Head and Neck Surgery,Affiliated Hospital of Guangdong Medical University,Guangzhou,524001,China., Pan W; Department of Otorhinolaryngology,Head and Neck Surgery,Affiliated Hospital of Guangdong Medical University,Guangzhou,524001,China., Mai Y; Department of Otorhinolaryngology,Head and Neck Surgery,Affiliated Hospital of Guangdong Medical University,Guangzhou,524001,China., Liu X; Department of Otorhinolaryngology,Head and Neck Surgery,Affiliated Hospital of Guangdong Medical University,Guangzhou,524001,China., Liu Y; Department of Otorhinolaryngology,Head and Neck Surgery,Affiliated Hospital of Guangdong Medical University,Guangzhou,524001,China., Xu W; Department of Otorhinolaryngology,Head and Neck Surgery,Affiliated Hospital of Guangdong Medical University,Guangzhou,524001,China.
المصدر: Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery [Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi] 2024 Jul; Vol. 38 (7), pp. 613-617.
نوع المنشور: English Abstract; Journal Article
بيانات الدورية: Publisher: Lin chuang er bi yan hou tou jing wai ke za zhi bain ji bu Country of Publication: China NLM ID: 101303164 Publication Model: Print Cited Medium: Print ISSN: 2096-7993 (Print) Linking ISSN: 20967993 NLM ISO Abbreviation: Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi Subsets: MEDLINE
مواضيع طبية MeSH: Papilloma, Inverted*/blood , Serpins*/blood , Antigens, Neoplasm*/blood, Humans ; Male ; Female ; Middle Aged ; Paranasal Sinus Neoplasms/blood ; Adult ; Nose Neoplasms/blood ; Clinical Relevance
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10دورية أكاديمية
المؤلفون: Blioskas S; 2nd Department of Otorhinolaryngology - Head and Neck Surgery, Aristotle University of Thessaloniki, Papageorgiou Hospital, Thessaloniki, Greece., Konstantinidis I; 2nd Department of Otorhinolaryngology - Head and Neck Surgery, Aristotle University of Thessaloniki, Papageorgiou Hospital, Thessaloniki, Greece., Antoniadis I; 2nd Department of Otorhinolaryngology - Head and Neck Surgery, Aristotle University of Thessaloniki, Papageorgiou Hospital, Thessaloniki, Greece., Kypriotou A; 2nd Department of Otorhinolaryngology - Head and Neck Surgery, Aristotle University of Thessaloniki, Papageorgiou Hospital, Thessaloniki, Greece., Hytiroglou P; Department of Pathology, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece., Markou K; 2nd Department of Otorhinolaryngology - Head and Neck Surgery, Aristotle University of Thessaloniki, Papageorgiou Hospital, Thessaloniki, Greece.
المصدر: Ear, nose, & throat journal [Ear Nose Throat J] 2024 Jun; Vol. 103 (6), pp. 373-376. Date of Electronic Publication: 2021 Nov 09.
نوع المنشور: Case Reports; Journal Article
بيانات الدورية: Publisher: SAGE Publications Country of Publication: United States NLM ID: 7701817 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-7522 (Electronic) Linking ISSN: 01455613 NLM ISO Abbreviation: Ear Nose Throat J Subsets: MEDLINE
مواضيع طبية MeSH: Ear Neoplasms*/pathology , Ear Neoplasms*/surgery , Ear Neoplasms*/diagnostic imaging , Ear, Middle*/pathology , Ear, Middle*/surgery , Ear, Middle*/diagnostic imaging , Papilloma, Inverted*/pathology , Papilloma, Inverted*/surgery , Papilloma, Inverted*/diagnosis , Papilloma, Inverted*/diagnostic imaging, Humans ; Tomography, X-Ray Computed