المؤلفون: Yim, Kendrick H, Prince, Thomas L, Qu, Shiwei, Bai, Fang, Jennings, Patricia A, Onuchic, José N, Theodorakis, Emmanuel A, Neckers, Leonard

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 113(33)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Computer Simulation, HEK293 Cells, HSP90 Heat-Shock Proteins, Humans, Mutagenesis, Site-Directed, Protein Domains, Protein Isoforms, Xanthones, molecular chaperone, heat-shock protein 90, isoform-specific inhibitor, molecular docking, caged xanthone

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6s88r49d

المؤلفون: Wei, Lei, Surma, Michelle, Shi, Stephanie, Lambert-Cheatham, Nathan, Shi, Jianjian

المصدر: Archivum Immunologiae et Therapiae Experimentalis. August 2016 64(4):259-278

المؤلفون: Yim, KH, Prince, TL, Qu, S, Bai, F, Jennings, PA, Onuchic, JN, Theodorakis, EA, Neckers, L

المصدر: Yim, KH; Prince, TL; Qu, S; Bai, F; Jennings, PA; Onuchic, JN; et al.(2016). Gambogic acid identifies an isoform-specific druggable pocket in the middle domain of Hsp90 beta. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113(33), E4801-E4809. doi: 10.1073/pnas.1606655113. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/6s88r49d

مصطلحات موضوعية: heat-shock protein 90, molecular docking, molecular chaperone, isoform-specific inhibitor, caged xanthone

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_______325::755bc1023e8281c88c114853f6bf2d87
http://www.escholarship.org/uc/item/6s88r49d

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المؤلفون: Lei Wei, Michelle Surma, Jianjian Shi, Nathan Lambert-Cheatham, Stephanie Shi

المصدر: Archivum Immunologiae et Therapiae Experimentalis

مصطلحات موضوعية: 0301 basic medicine, ROCK isoform-specific inhibitor, RHOA, Cancer therapy, Cell Survival, Immunology, Apoptosis, Review, Biology, Metastasis, 03 medical and health sciences, Cell Movement, Neoplasms, Cell Adhesion, medicine, Humans, Protein Isoforms, Immunology and Allergy, Rho kinase, ROCK1, Rho kinase pan-inhibitor, ROCK2, Neoplasm Metastasis, Cell adhesion, Rho-associated protein kinase, Cell Proliferation, rho-Associated Kinases, Polymorphism, Genetic, Neovascularization, Pathologic, Kinase, General Medicine, medicine.disease, Actin cytoskeleton, 3. Good health, Cell biology, MicroRNAs, 030104 developmental biology, Drug Resistance, Neoplasm, Mutation, Disease Progression, Neoplastic Stem Cells, biology.protein, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f36bfc89f73b5e6fa9ffb60e3622dbd4

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