المؤلفون: Gangwar SP; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA., Yelshanskaya MV; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA., Nadezhdin KD; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA., Yen LY; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.; Cellular and Molecular Physiology and Biophysics Graduate Program, Columbia University Irving Medical Center, New York, NY, USA., Newton TP; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.; Integrated Program in Cellular, Molecular and Biomedical Studies, Columbia University Irving Medical Center, New York, NY, USA., Aktolun M; Department of Chemistry, Carnegie Mellon University, Pittsburgh, PA, USA., Kurnikova MG; Department of Chemistry, Carnegie Mellon University, Pittsburgh, PA, USA., Sobolevsky AI; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA. as4005@cumc.columbia.edu.

المصدر: Nature [Nature] 2024 Jun; Vol. 630 (8017), pp. 762-768. Date of Electronic Publication: 2024 May 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Cryoelectron Microscopy* , Receptors, Kainic Acid*/chemistry , Receptors, Kainic Acid*/metabolism , Receptors, Kainic Acid*/ultrastructure , Ion Channel Gating* , Models, Molecular* , GluK2 Kainate Receptor* , Glutamic Acid*/metabolism , Glutamic Acid*/chemistry , Concanavalin A*/chemistry , Concanavalin A*/metabolism , Concanavalin A*/pharmacology , Protein Domains*, Humans ; Animals ; Ligands ; Allosteric Regulation ; Binding Sites

المؤلفون: Kunde SA; Neuroscience Research Center NWFZ, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Schmerl B; Neuroscience Research Center NWFZ, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., von Sivers J; Neuroscience Research Center NWFZ, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Ahmadyar E; Neuroscience Research Center NWFZ, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Gupta T; Neuroscience Research Center NWFZ, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Rademacher N; Neuroscience Research Center NWFZ, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; German Center for Neurodegenerative Diseases (DZNE) Berlin, Berlin, Germany., Zieger HL; Neuroscience Research Center NWFZ, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; CNRS, Interdisciplinary Institute for Neuroscience (IINS), UMR 5297, University of Bordeaux, Bordeaux, France., Shoichet SA; Neuroscience Research Center NWFZ, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany. Electronic address: sarah.shoichet@charite.de.

المصدر: The Journal of biological chemistry [J Biol Chem] 2024 May; Vol. 300 (5), pp. 107263. Date of Electronic Publication: 2024 Apr 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Dendritic Spines*/metabolism , GluK2 Kainate Receptor* , Receptors, Kainic Acid*/metabolism , Receptors, Kainic Acid*/genetics, Animals ; Humans ; Rats ; Cell Membrane/metabolism ; Hippocampus/metabolism ; Hippocampus/cytology ; Intracellular Signaling Peptides and Proteins/metabolism ; Intracellular Signaling Peptides and Proteins/genetics ; Membrane Proteins/metabolism ; Membrane Proteins/genetics ; Mitogen-Activated Protein Kinase 10/metabolism ; Mitogen-Activated Protein Kinase 10/genetics ; Neurons/metabolism ; Neuropeptides ; Phosphorylation ; Protein Transport ; Synapses/metabolism ; Cells, Cultured

المؤلفون: Cai W; Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA., Zhang W; Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA., Zheng Q; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Hor CC; Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI, USA., Pan T; Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA., Fatima M; Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI, USA., Dong X; The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Duan B; Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI, USA. bduan@umich.edu., Xu XZS; Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA. shawnxu@umich.edu.; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA. shawnxu@umich.edu.

المصدر: Nature neuroscience [Nat Neurosci] 2024 Apr; Vol. 27 (4), pp. 679-688. Date of Electronic Publication: 2024 Mar 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1726 (Electronic) Linking ISSN: 10976256 NLM ISO Abbreviation: Nat Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: GluK2 Kainate Receptor*/metabolism , Receptors, Kainic Acid*/genetics , Receptors, Kainic Acid*/metabolism, Animals ; Mice ; Caenorhabditis elegans/metabolism ; Cold Temperature ; Glutamic Acid ; Mammals/metabolism ; Neurons/metabolism ; Synaptic Transmission

المؤلفون: Iida I; Division of Oral Biochemistry, Faculty of Dentistry & Graduate School of Medical and Dental Sciences, Niigata University, Niigata, 951-8514, Japan.; Research Center for Advanced Oral Science, Faculty of Dentistry & Graduate School of Medical and Dental Sciences, Niigata University, Niigata, 951-8514, Japan.; Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Meguro, Tokyo, 153-8902, Japan., Konno K; Department of Anatomy, Faculty of Medicine, Hokkaido University, Sapporo, 060-8638, Japan., Natsume R; Department of Animal Model Development, Brain Research Institute, Niigata University, Niigata, 951-8585, Japan., Abe M; Department of Animal Model Development, Brain Research Institute, Niigata University, Niigata, 951-8585, Japan., Watanabe M; Department of Anatomy, Faculty of Medicine, Hokkaido University, Sapporo, 060-8638, Japan., Sakimura K; Department of Animal Model Development, Brain Research Institute, Niigata University, Niigata, 951-8585, Japan. sakimura@bri.niigata-u.ac.jp., Terunuma M; Division of Oral Biochemistry, Faculty of Dentistry & Graduate School of Medical and Dental Sciences, Niigata University, Niigata, 951-8514, Japan. mterunuma@dent.niigata-u.ac.jp.

المصدر: Scientific reports [Sci Rep] 2024 Feb 24; Vol. 14 (1), pp. 4521. Date of Electronic Publication: 2024 Feb 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Kainic Acid*/genetics , Receptors, Kainic Acid*/metabolism , GluK3 Kainate Receptor*, Mice ; Animals ; Humans ; Mice, Inbred C57BL ; Receptors, Ionotropic Glutamate ; Anxiety/genetics

المؤلفون: Guo R; Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China., Xue J; Department of Anesthesiology, Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730050, Gansu, China., Shao P; Department of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China., Cai C; Department of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China., Wang Y; Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China. Electronic address: wangyun129@ccmu.edu.cn.

المصدر: Neuroscience letters [Neurosci Lett] 2023 Sep 14; Vol. 813, pp. 137430. Date of Electronic Publication: 2023 Aug 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Scientific Publishers Ireland Country of Publication: Ireland NLM ID: 7600130 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7972 (Electronic) Linking ISSN: 03043940 NLM ISO Abbreviation: Neurosci Lett Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, AMPA*/metabolism , Spinal Cord Dorsal Horn*/metabolism, Animals ; Rats ; Pain, Postoperative/metabolism ; Posterior Horn Cells/metabolism ; RNA, Small Interfering/metabolism ; GluK2 Kainate Receptor

المؤلفون: Peng J; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Zhang Q; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Lin F; Department of Oncology, Guangdong Provincial Hospital of Integrated Traditional Chinese & Western Medicine, Affiliated Nanhai Hospital of Traditional Chinese Medicine of Jinan University, Foshan, Guangdong Province, 528200, China., Ke C; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Deng W; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Yang A; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Su X; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.

المصدر: Epigenomics [Epigenomics] 2023 Nov; Vol. 15 (21), pp. 1101-1119. Date of Electronic Publication: 2023 Nov 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Future Medicine Country of Publication: England NLM ID: 101519720 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1750-192X (Electronic) Linking ISSN: 1750192X NLM ISO Abbreviation: Epigenomics Subsets: MEDLINE

مواضيع طبية MeSH: Proto-Oncogene Proteins B-raf*/genetics , Thyroid Neoplasms*/genetics , Thyroid Neoplasms*/pathology, Humans ; DNA Methylation ; Epigenesis, Genetic ; Lymphatic Metastasis ; Mutation ; GluK2 Kainate Receptor

المؤلفون: Barthet G; Université of Bordeaux, CNRS, Interdisciplinary Institute for Neuroscience (IINS), UMR 5297, F-33000 Bordeaux, France., Moreira-de-Sá A; Université of Bordeaux, CNRS, Interdisciplinary Institute for Neuroscience (IINS), UMR 5297, F-33000 Bordeaux, France., Zhang P; Université of Bordeaux, CNRS, Interdisciplinary Institute for Neuroscience (IINS), UMR 5297, F-33000 Bordeaux, France., Deforges S; Université of Bordeaux, CNRS, Interdisciplinary Institute for Neuroscience (IINS), UMR 5297, F-33000 Bordeaux, France., Castanheira J; Université of Bordeaux, CNRS, Interdisciplinary Institute for Neuroscience (IINS), UMR 5297, F-33000 Bordeaux, France., Gorlewicz A; Université of Bordeaux, CNRS, Interdisciplinary Institute for Neuroscience (IINS), UMR 5297, F-33000 Bordeaux, France., Mulle C; Université of Bordeaux, CNRS, Interdisciplinary Institute for Neuroscience (IINS), UMR 5297, F-33000 Bordeaux, France christophe.mulle@u-bordeaux.fr.

المصدر: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2022 Dec 07; Vol. 42 (49), pp. 9253-9262. Date of Electronic Publication: 2022 Oct 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Amyloid Precursor Protein Secretases*/metabolism , Kainic Acid*/pharmacology , Presenilin-1*/metabolism , Receptors, Kainic Acid*/metabolism, Animals ; Female ; Male ; Mice ; Alzheimer Disease/genetics ; Alzheimer Disease/metabolism ; Amyloid beta-Protein Precursor/genetics ; Amyloid beta-Protein Precursor/metabolism ; Mossy Fibers, Hippocampal/physiology ; Presenilins/metabolism ; Synapses/physiology ; GluK2 Kainate Receptor

المؤلفون: Chałupnik P; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College in Kraków, 30-688 Kraków, Poland., Vialko A; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College in Kraków, 30-688 Kraków, Poland., Pickering DS; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark., Hinkkanen M; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark., Donbosco S; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark., Møller TC; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark., Jensen AA; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark., Nielsen B; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark., Bay Y; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark., Kristensen AS; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark., Johansen TN; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark., Łątka K; Department of Physicochemical Drug Analysis, Jagiellonian University Medical College in Kraków, 30-688 Kraków, Poland., Bajda M; Department of Physicochemical Drug Analysis, Jagiellonian University Medical College in Kraków, 30-688 Kraków, Poland., Szymańska E; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College in Kraków, 30-688 Kraków, Poland.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2022 Aug 08; Vol. 23 (15). Date of Electronic Publication: 2022 Aug 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Kainic Acid*/metabolism, Ligands ; Molecular Docking Simulation ; Protein Domains ; GluK3 Kainate Receptor

المؤلفون: Gorlewicz A; Interdisciplinary Institute for Neuroscience, UMR 5297, Centre National de la Recherche Scientifique, F-33000 Bordeaux, France.; Interdisciplinary Institute for Neuroscience, UMR 5297, University of Bordeaux, F-33000 Bordeaux, France.; Laboratory of Molecular and Systemic Neuromorphology, Nencki Institute of Experimental Biology, 02-093 Warsaw, Poland., Barthet G; Interdisciplinary Institute for Neuroscience, UMR 5297, Centre National de la Recherche Scientifique, F-33000 Bordeaux, France.; Interdisciplinary Institute for Neuroscience, UMR 5297, University of Bordeaux, F-33000 Bordeaux, France., Zucca S; Interdisciplinary Institute for Neuroscience, UMR 5297, Centre National de la Recherche Scientifique, F-33000 Bordeaux, France.; Interdisciplinary Institute for Neuroscience, UMR 5297, University of Bordeaux, F-33000 Bordeaux, France., Vincent P; Interdisciplinary Institute for Neuroscience, UMR 5297, Centre National de la Recherche Scientifique, F-33000 Bordeaux, France.; Interdisciplinary Institute for Neuroscience, UMR 5297, University of Bordeaux, F-33000 Bordeaux, France., Griguoli M; Interdisciplinary Institute for Neuroscience, UMR 5297, Centre National de la Recherche Scientifique, F-33000 Bordeaux, France.; Interdisciplinary Institute for Neuroscience, UMR 5297, University of Bordeaux, F-33000 Bordeaux, France., Grosjean N; Interdisciplinary Institute for Neuroscience, UMR 5297, Centre National de la Recherche Scientifique, F-33000 Bordeaux, France.; Interdisciplinary Institute for Neuroscience, UMR 5297, University of Bordeaux, F-33000 Bordeaux, France., Wilczynski G; Laboratory of Molecular and Systemic Neuromorphology, Nencki Institute of Experimental Biology, 02-093 Warsaw, Poland., Mulle C; Interdisciplinary Institute for Neuroscience, UMR 5297, Centre National de la Recherche Scientifique, F-33000 Bordeaux, France.; Interdisciplinary Institute for Neuroscience, UMR 5297, University of Bordeaux, F-33000 Bordeaux, France.

المصدر: Cerebral cortex (New York, N.Y. : 1991) [Cereb Cortex] 2022 Jul 12; Vol. 32 (14), pp. 2907-2923.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9110718 Publication Model: Print Cited Medium: Internet ISSN: 1460-2199 (Electronic) Linking ISSN: 10473211 NLM ISO Abbreviation: Cereb Cortex Subsets: MEDLINE

مواضيع طبية MeSH: Kainic Acid* , Pilocarpine*/toxicity , Receptors, Kainic Acid*/genetics, CA1 Region, Hippocampal/metabolism ; Cholinergic Agents/pharmacology ; Gene Deletion ; Humans ; Pyramidal Cells/metabolism ; Seizures/chemically induced ; Seizures/genetics ; GluK2 Kainate Receptor

المؤلفون: Zhu Y; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Armstrong JN; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Contractor A; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA; Department of Neurobiology, Northwestern University, Chicago, IL 60611, USA. Electronic address: a-contractor@northwestern.edu.

المصدر: Cell reports [Cell Rep] 2021 Sep 21; Vol. 36 (12), pp. 109751.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Dentate Gyrus/*physiology , Receptors, Kainic Acid/*metabolism, Action Potentials/drug effects ; Animals ; Behavior, Animal ; Dentate Gyrus/pathology ; Fear ; GABAergic Neurons/metabolism ; In Vitro Techniques ; Kainic Acid/analogs & derivatives ; Kainic Acid/pharmacology ; Memory ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Receptors, Kainic Acid/agonists ; Receptors, Kainic Acid/genetics ; Signal Transduction ; GluK2 Kainate Receptor