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المؤلفون: Sulman, Muhammad
المساهمون: Lääketieteen laitos, School of Medicine, Terveystieteiden tiedekunta, Lääketieteen laitos, Biolääketiede, Faculty of Health Sciences, School of Medicine, Biomedicine, Terveystieteiden tiedekunta, Faculty of Health Sciences
مصطلحات موضوعية: drug design, sinnesceller, biomedicine, cancerous diseases, läkemedelsdesign, aistinreseptorit, lääkesuunnittelu, sensory receptor cells, lääkkeet, Computer-aided drug design, Receptor tyrosine kinases, Molecular docking, tyrosin, syöpätaudit, tyrosiini, läkemedel, biolääketiede, Epidermal, cancersjukdomar, medicines, tyrosine
وصف الملف: fulltext; Julkaisun kokoteksti; Fulltext of publication
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http://urn.fi/urn:nbn:fi:uef-20220729 -
2Lead optimization for 3-acylaminoindazole for Adapter Associated Kinase 1 and BMP-2 inducible kinase
المؤلفون: Ghosh, Swarnendu
المساهمون: Lääketieteen laitos, School of Medicine, Terveystieteiden tiedekunta, Lääketieteen laitos, Biolääketiede, Faculty of Health Sciences, School of Medicine, Biomedicine, Terveystieteiden tiedekunta, Faculty of Health Sciences
مصطلحات موضوعية: kinaasit, entsyymit, drug design, enzymer, enzymes, biomedicine, läkemedelsdesign, proteins, lääkesuunnittelu, lääkkeet, kinases, kinaser, proteiner, läkemedel, biolääketiede, proteiinit, medicines
وصف الملف: fulltext; Julkaisun kokoteksti; Fulltext of publication
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http://urn.fi/urn:nbn:fi:uef-20220718 -
3
المصدر: European journal of medicinal chemistry. 237
مصطلحات موضوعية: Pharmacology, aromaattiset yhdisteet, Scaffold hopping, Chemistry, Pharmaceutical, Organic Chemistry, General Medicine, Azulenes, lääkesuunnittelu, Photostability, lääkekemia, Indole, Drug Discovery, atsuleeni, biologinen aktiivisuus, Naphthalene
وصف الملف: application/pdf; fulltext
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المؤلفون: Vladimir Mironov, Irina A. Shchugoreva, Polina V. Artyushenko, Dmitry Morozov, Nicola Borbone, Giorgia Oliviero, Tatiana N. Zamay, Roman V. Moryachkov, Olga S. Kolovskaya, Kirill A. Lukyanenko, Yanling Song, Iuliia A. Merkuleva, Vladimir N. Zabluda, Georgy Peters, Lyudmila S. Koroleva, Dmitry V. Veprintsev, Yury E. Glazyrin, Ekaterina A. Volosnikova, Svetlana V. Belenkaya, Tatiana I. Esina, Anastasiya A. Isaeva, Valentina S. Nesmeyanova, Daniil V. Shanshin, Anna N. Berlina, Nadezhda S. Komova, Valery A. Svetlichnyi, Vladimir N. Silnikov, Dmitriy N. Shcherbakov, Galina S. Zamay, Sergey S. Zamay, Tatyana Smolyarova, Elena P. Tikhonova, Kelvin H.‐C. Chen, U‐Ser Jeng, Gerolama Condorelli, Vittorio Franciscis, Gerrit Groenhof, Chaoyong Yang, Alexander A. Moskovsky, Dmitri G. Fedorov, Felix N. Tomilin, Weihong Tan, Yuri Alexeev, Maxim V. Berezovski, Anna S. Kichkailo
المساهمون: Mironov, Vladimir, Shchugoreva, Irina A., Artyushenko, Polina V., Morozov, Dmitry, Borbone, Nicola, Oliviero, Giorgia, Zamay, Tatiana N., Moryachkov, Roman V., Kolovskaya, Olga S., Lukyanenko, Kirill A., Song, Yangling, Merkuleva, Iuliia A., Zabluda, Vladimir N., Peters, Georgy, Koroleva, Lyudmila S., Veprintsev, Dmitry V., Glazyrin, Yury E., Volosnikova, Ekaterina A., Belenkaya, Svetlana V., Esina, Tatiana I., Isaeva, Anastasiya A., Nesmeyanova, Valentina S., Shanshin, Daniil V., Berlina, Anna N., Komova, Nadezhda S., Svetlichnyi, Valery A., Silnikov, Vladimir N., Shcherbakov, Dmitriy N., Zamay, Galina S., Zamay, Sergey S., Smolyarova, Tatyana, Tikhonova, Elena P., Chen, Kelvin H. -C., Jeng, U-Ser, Condorelli, Gerolama, de Franciscis, Vittorio, Groenhof, Gerrit, Yang, Chaoyong, Moskovsky, Alexander A., Fedorov, Dmitri G., Tomilin, Felix N., Tan, Weihong, Alexeev, Yuri, Berezovski, Maxim V., Kichkailo, Anna S
المصدر: Chemistry-A European journal. 2022. Vol. 28, № 12. P. e202104481 (1-16)
Chemistry, vol 28مصطلحات موضوعية: oligonukleotidit, aptamers, fragment molecular orbitals method, molecular dynamics, SARS-CoV-2, SAXS, fragment molecular orbitals method, SARS-CoV-2, SELEX Aptamer Technique, Organic Chemistry, aptamers, SARS-CoV-2-virus, COVID-19, SAXS, General Chemistry, Aptamers, Nucleotide, Molecular Dynamics Simulation, laskennallinen kemia, molecular dynamics, Catalysis, lääkesuunnittelu, Molecular Docking Simulation, SARS-CoV-2, белки, Spike Glycoprotein, Coronavirus, Humans, дизайн аптамеров, molekyylidynamiikka, proteiinit
وصف الملف: application/pdf; fulltext
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المؤلفون: Mira Ahinko, Sanna Niinivehmas, Elmeri M. Jokinen, Olli T. Pentikäinen
المصدر: Chemical Biology & Drug Design. 93:522-538
مصطلحات موضوعية: Molecular model, Binding energy, ta3111, Ligands, Energy minimization, 01 natural sciences, Biochemistry, lääkesuunnittelu, Substrate Specificity, Cytochrome P-450 CYP2A6, Free energy perturbation, Coumarins, Drug Discovery, Humans, ta317, Pharmacology, Binding Sites, molecular modeling, 010405 organic chemistry, Chemistry, Drug discovery, Organic Chemistry, ta1182, ligandit, receptor and ligands, laskennallinen kemia, Ligand (biochemistry), Protein Structure, Tertiary, 0104 chemical sciences, Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, Docking (molecular), structure based drug-design, Thermodynamics, Molecular Medicine, proteiinit, Target protein, Biological system, Protein Binding
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المؤلفون: Medarametla, Prasanthi
المساهمون: Terveystieteiden tiedekunta, Faculty of Health Sciences
مصطلحات موضوعية: Models, Molecular, lääkesuunnittelu, Anti-Bacterial Agents, soluviestintä, bakteeritaudit, Bacterial Infections, Malate Synthase, Pseudomonas Infections, Drug Resistance, Bacterial, Quorum Sensing, Catalytic Domain, entsyymit, Virulence, Gram-Negative Bacteria, mallintaminen, Drug Design, virulenssi, antibiootit, antibioottiresistenssi, Drug Discovery
وصف الملف: fulltext; Julkaisun kokoteksti; Fulltext of publication
URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______3891::561638ea8ea50438e350d368ae611860
http://urn.fi/URN:ISBN:978-952-61-3491-8 -
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المؤلفون: Heikkinen, Emma
المساهمون: Farmasian laitos, School of Pharmacy, Terveystieteiden tiedekunta, Farmasian laitos, Faculty of Health Sciences, School of Pharmacy, Terveystieteiden tiedekunta, Faculty of Health Sciences
مصطلحات موضوعية: lääkesuunnittelu, aihiolääkkeet, annostelu, Pharmacokinetics, Ganciclovir, Eye Diseases, hydrolyysi, Injections, Intraocular, Drug Development, lääkkeet, silmät, injektiot, Prodrugs, Administration, Ophthalmic, silmätaudit, Pharmaceutical Preparations, Esterases, Eye, Lens, Crystalline, lääkeaineet, aineenvaihdunta, Drug Delivery Systems, Drug Design, Hydrolysis, farmakokinetiikka
وصف الملف: Julkaisusta vain yhteenveto-osa
URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______3891::fef4e2eebb2706f03634b681a07e8100
http://urn.fi/URN:ISBN:978-952-61-3451-2 -
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المؤلفون: Sanna Niinivehmas, Elina Multamäki, Pekka A. Postila, Sakari Lätti, Klaus R. Liedl, Olli T. Pentikäinen, Sanna Rauhamäki
المصدر: ACS Omega
ACS Omega, Vol 3, Iss 6, Pp 6259-6266 (2018)مصطلحات موضوعية: lymphocytes, 0301 basic medicine, drug design, General Chemical Engineering, In silico, Retinoic acid, Structural diversity, Computational biology, ta3111, Scaffold hopping, 01 natural sciences, Article, lääkesuunnittelu, lcsh:Chemistry, 03 medical and health sciences, chemistry.chemical_compound, RAR-related orphan receptor gamma, Inverse agonist, Orphan receptor, ligands, Chemistry, ta1182, ligandit, General Chemistry, proteins, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 030104 developmental biology, lcsh:QD1-999, Docking (molecular), proteiinit, lymfosyytit
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المصدر: Pharmaceutics
Volume 11
Issue 9
Pharmaceutics, Vol 11, Iss 9, p 475 (2019)مصطلحات موضوعية: maha-suolitulehdus, lcsh:RS1-441, Pharmaceutical Science, bacteriophage therapy, E. coli, Article, Dosage form, bakteriofagit, RS, law.invention, lääkesuunnittelu, lcsh:Pharmacy and materia medica, 03 medical and health sciences, Confocal microscopy, law, Escherichia, enterobakteerit, Membrane emulsification, 030304 developmental biology, 0303 health sciences, Chromatography, biology, kalvot (tekniikka), 030306 microbiology, Chemistry, enteric infections, biology.organism_classification, Controlled release, In vitro, QR, 3. Good health, fagiterapia, mikrorakenteet, pH-triggered release, Cell culture, Gastric acid, microencapsulation, controlled release, Eudragit S100
وصف الملف: application/pdf; fulltext
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المؤلفون: Ramsay, Eva
المساهمون: Farmasian laitos, School of Pharmacy, Terveystieteiden tiedekunta, Farmasian laitos, Faculty of Health Sciences, School of Pharmacy, Terveystieteiden tiedekunta, Faculty of Health Sciences
مصطلحات موضوعية: Polymers, www.yso.fi/onto/yso/p19404 [permeabilitet - yso/swe$$0http], Ocular Absorption, Administration, Topical, Drug Evaluation, Preclinical, Quantitative Structure-Activity Relationship, www.yso.fi/onto/yso/p21727 [hornhinna - yso/swe$$0http], Administration, Ophthalmic, www.yso.fi/onto/yso/p18324 [ögon - yso/swe$$0http], Retinal Pigment Epithelium, Eye, www.yso.fi/onto/yso/p8930 [vapautuminen - yso/fin$$0http], Cornea, www.yso.fi/onto/yso/p9029 [annostelu - yso/fin$$0http], www.yso.fi/onto/yso/p10851 [medicinering - yso/swe$$0http], Drug Delivery Systems, farmasia, www.yso.fi/onto/yso/p18324 [silmät - yso/fin$$0http], RNA, Small Interfering, www.yso.fi/onto/yso/p1077 [läkemedel - yso/swe$$0http], www.yso.fi/onto/yso/p21727 [sarveiskalvo - yso/fin$$0http], www.yso.fi/onto/yso/p926 [polymeerit - yso/fin$$0http], Microspheres, www.yso.fi/onto/yso/p8930 [frigårelse - yso/swe$$0http], www.yso.fi/onto/yso/p25180 [läkemedelsdesign - yso/swe$$0http], www.yso.fi/onto/yso/p1737 [farmakokinetik - yso/swe$$0http], www.yso.fi/onto/yso/p4230 [utveckling (verksamhet) - yso/swe$$0http], Intravitreal Injections, www.yso.fi/onto/yso/p3657 [uppsugning - yso/swe$$0http], Conjunctiva, pharmacy, www.yso.fi/onto/yso/p4230 [kehittäminen - yso/fin$$0http], Permeability, Drug Development, www.yso.fi/onto/yso/p926 [polymerer - yso/swe$$0http], www.yso.fi/onto/yso/p1077 [lääkkeet - yso/fin$$0http], www.yso.fi/onto/yso/p19404 [läpäisevyys - yso/fin$$0http], Pharmacokinetics, www.yso.fi/onto/yso/p9029 [dosering - yso/swe$$0http], www.yso.fi/onto/yso/p1737 [farmakokinetiikka - yso/fin$$0http], Interleukin-6, www.yso.fi/onto/yso/p21732 [verkkokalvo - yso/fin$$0http], www.yso.fi/onto/yso/p3657 [imeytyminen - yso/fin$$0http], www.yso.fi/onto/yso/p21732 [näthinna - yso/swe$$0http], Eye Diseases - drug therapy, Drug Liberation, www.yso.fi/onto/yso/p25180 [lääkesuunnittelu - yso/fin$$0http], www.yso.fi/onto/yso/p10851 [lääkehoito - yso/fin$$0http], www.yso.fi/onto/yso/p12047 [silmätaudit - yso/fin$$0http], www.yso.fi/onto/yso/p12047 [ögonsjukdomar - yso/swe$$0http]
وصف الملف: Julkaisusta vain yhteenveto-osa
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http://urn.fi/URN:ISBN:978-952-61-3054-5
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