المؤلفون: Ying Qin, Dekang Li, Chunting Qi, Huaijiang Xiang, Huyan Meng, Jingli Liu, Shaoqing Zhou, Xinyu Gong, Ying Li, Guifang Xu, Rui Zu, Hang Xie, Yechun Xu, Gang Xu, Zheng Zhang, Shi Chen, Lifeng Pan, Li Tan

المصدر: Acta Pharmaceutica Sinica B, Vol 14, Iss 1, Pp 319-334 (2024)

مصطلحات موضوعية: RIPK1, Necroptosis, Type-II kinase inhibitors, Rational design, Lead optimization, Structure‒activity relationship, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211383523004215; https://doaj.org/toc/2211-3835

URL الوصول: https://doaj.org/article/d923a9cf0f7544d983270d45a93222cd

المؤلفون: Gregory A. Landrum, Maximilian Beckers, Jessica Lanini, Nadine Schneider, Nikolaus Stiefl, Sereina Riniker

المصدر: Journal of Cheminformatics, Vol 15, Iss 1, Pp 1-16 (2023)

مصطلحات موضوعية: Lead optimization, Cross-validation, Machine learning, Information technology, T58.5-58.64, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1758-2946

URL الوصول: https://doaj.org/article/560e2e5559bf491d8bf3bd83ce87ad62

المؤلفون: Landrum, Gregory A.^{Aff1, IDs13321023007879_cor1}, Beckers, Maximilian, Lanini, Jessica, Schneider, Nadine, Stiefl, Nikolaus^{Aff2, Aff3}, Riniker, Sereina^{Aff1, IDs13321023007879_cor6}

المصدر: Journal of Cheminformatics. 15(1)

المؤلفون: Amara, Kenza^{Aff1, Aff3}, Rodríguez-Pérez, Raquel^{Aff2, IDs13321023007339_cor2}, Jiménez-Luna, José^{Aff1, IDs13321023007339_cor3}

المصدر: Journal of Cheminformatics. 15(1)

المؤلفون: Lou, Chaofeng, Yang, Hongbin, Deng, Hua, Huang, Mengting, Li, Weihua, Liu, Guixia, Lee, Philip W., Tang, Yun^{Aff1, IDs1332102300707x_cor8}

المصدر: Journal of Cheminformatics. 15(1)

المؤلفون: Yang, Chih-Chieh, Domeniconi, Giacomo, Zhang, Leili, Cong, Guojing

المصدر: 2020 IEEE International Conference on Big Data (Big Data) Big Data (Big Data), 2020 IEEE International Conference on. :5861-5863 Dec, 2020

Relation: 2020 IEEE International Conference on Big Data (Big Data)

المؤلفون: Varikoti, Rohith Anand, Schultz, Katherine J., Kombala, Chathuri J., Kruel, Agustin, Brandvold, Kristoffer R., Zhou, Mowei, Kumar, Neeraj^{Aff1, IDs10822023005091_cor7}

المصدر: Journal of Computer-Aided Molecular Design: Incorporating Perspectives in Drug Discovery and Design. 37(8):339-355

المؤلفون: Zahra Azhar, Richard P. Grose, Afsheen Raza, Zohaib Raza

المصدر: Exploration of Targeted Anti-tumor Therapy, Vol 4, Iss 4, Pp 727-742 (2023)

مصطلحات موضوعية: cancer drug development, tyrosine kinase inhibitors, drug resistance, computational modelling, molecular docking, target identification, lead optimization, targeted cancer therapy, Internal medicine, RC31-1245

وصف الملف: electronic resource

Relation: https://www.explorationpub.com/Journals/etat/Article/1002164; https://doaj.org/toc/2692-3114

URL الوصول: https://doaj.org/article/4c987951c077468e85c75acd709fab33

المؤلفون: Al bustanji, Du’a, Alnabulsi, Soraya^{Aff1, IDs00044023030466_cor2}, Al-Hurani, Enas A.

المصدر: Medicinal Chemistry Research. 32(5):910-929

المؤلفون: Chaofeng Lou, Hongbin Yang, Hua Deng, Mengting Huang, Weihua Li, Guixia Liu, Philip W. Lee, Yun Tang

المصدر: Journal of Cheminformatics, Vol 15, Iss 1, Pp 1-14 (2023)

مصطلحات موضوعية: Mutagenicity optimization, Lead optimization, Matched molecular pairs analysis, Machine learning, Consensus model, Information technology, T58.5-58.64, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1758-2946

URL الوصول: https://doaj.org/article/ab66073423da40079716e4a89cc25c52