المؤلفون: Pearce, David, Manis, Anna D, Nesterov, Viatcheslav, Korbmacher, Christoph

المصدر: Pflügers Archiv - European Journal of Physiology. 474(8)

مصطلحات موضوعية: Medical Physiology, Biomedical and Clinical Sciences, Kidney Disease, Aldosterone, Electrolytes, Epithelial Sodium Channels, Homeostasis, Ion Transport, Kidney Tubules, Distal, Sodium, Solute Carrier Family 12, Member 3, Na+-Cl- cotransporter, Epithelial sodium channel, Renal outer medullary K+ channel, Mineralocorticoid receptor, beta-hydroxysteroid dehydrogenase type 2, Serum and glucocorticoid-regulated kinase 1, mTOR complex 2, With no lysine, Kinase 1 and 4, Aldosterone-sensitive distal nephron, Early distal convoluted tubule, Late distal convoluted tubule, Connecting tubule, Cortical collecting duct, 11ß-hydroxysteroid dehydrogenase type 2, Na+-Cl− cotransporter, Serum and glucocorticoid-regulated kinase 1 (SGK1), mTOR complex 2, Physiology, Human Movement and Sports Sciences, Biochemistry and cell biology, Zoology, Medical physiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/24g8v3wt

المؤلفون: Fan, QiWen, Aksoy, Ozlem, Wong, Robyn A, Ilkhanizadeh, Shirin, Novotny, Chris J, Gustafson, William C, Truong, Albert Yi-Que, Cayanan, Geraldine, Simonds, Erin F, Haas-Kogan, Daphne, Phillips, Joanna J, Nicolaides, Theodore, Okaniwa, Masanori, Shokat, Kevan M, Weiss, William A

المصدر: Cancer Cell. 31(3)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Rare Diseases, Orphan Drug, Neurosciences, Brain Cancer, Brain Disorders, Cancer, Animals, Brain Neoplasms, Cell Line, Tumor, Female, Glioblastoma, Humans, Mechanistic Target of Rapamycin Complex 1, Mice, Mice, Inbred BALB C, Multiprotein Complexes, Protein Kinase Inhibitors, Sirolimus, TOR Serine-Threonine Kinases, Tacrolimus Binding Protein 1A, FKBP12, FK506 binding protein 12, FRB, FK506 rapamycin binding, GBM, glioblastoma, PI3K, phosphatidylinositol 3' kinase, TORKi, mTOR kinase inhibitor, mTOR mechanistic target of rapamycin, mTORC1, mTOR complex 1, mTORC2, mTOR complex 2, Oncology & Carcinogenesis, Biochemistry and cell biology, Oncology and carcinogenesis

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/31f4p10w
https://escholarship.org/content/qt31f4p10w/qt31f4p10w.pdf

المؤلفون: Yoo-Jin Lee, Jongsun Kim

المصدر: International Journal of Molecular Sciences, Vol 21, Iss 24, p 9575 (2020)

مصطلحات موضوعية: NK cells, resveratrol, Akt, mTOR complex 2, c-Myb, Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1422-0067/21/24/9575; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067

URL الوصول: https://doaj.org/article/00a2a07885eb4aad9f30db99ad289ef0

المؤلفون: Kenneth Maiese

المصدر: Neural Regeneration Research, Vol 11, Iss 3, Pp 372-385 (2016)

مصطلحات موضوعية: Akt, AMP activated protein kinase (AMPK), apoptosis, Alzheimer′s disease, autophagy, β-cell, cancer, cardiovascular disease, caspase, CCN family, diabetes mellitus, epidermal growth factor, erythropoietin, fibroblast growth factor, forkhead transcription factors, FoxO, FRAP1, hamartin (tuberous sclerosis 1)/tuberin (tuberous sclerosis 2) (TSC1/TSC2), insulin, mechanistic target of rapamycin (mTOR), mTOR Complex 1 (mTORC1), mTOR Complex 2 (mTORC2), nicotinamide, nicotinamide adenine dinucleotide (NAD + ), non-communicable diseases, oxidative stress, phosphoinositide 3-kinase (PI 3-K), programmed cell death, silent mating type information regulation 2 homolog 1 (Saccharomyces cerevisiae) (SIRT1), sirtuin, stem cells, wingless, Wnt, Wnt1 inducible signaling pathway protein 1 (WISP1), Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://www.nrronline.org/article.asp?issn=1673-5374;year=2016;volume=11;issue=3;spage=372;epage=385;aulast=Maiese; https://doaj.org/toc/1673-5374

URL الوصول: https://doaj.org/article/0ebb77e959ac4059a10ccd5de769792d

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المؤلفون: Weiwei Sun, Hui Wang, Jialing He, Zibo Liu, Xiaoqin Yuan

المصدر: International Journal of Biological Sciences

مصطلحات موضوعية: breast cancer bone metastasis, Osteoclasts, Bone Neoplasms, Breast Neoplasms, Mechanistic Target of Rapamycin Complex 2, Applied Microbiology and Biotechnology, mTORC2, osteolytic bone destruction, 03 medical and health sciences, Mice, Downregulation and upregulation, Osteoclast, Osteogenesis, Cell Line, Tumor, medicine, Animals, Molecular Biology, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Cathepsin, 0303 health sciences, biology, Chemistry, CAFs, Mesenchymal stem cell, digestive, oral, and skin physiology, Bone metastasis, Cancer, Mesenchymal Stem Cells, Cell Biology, medicine.disease, medicine.anatomical_structure, Rapamycin-Insensitive Companion of mTOR Protein, RANKL, mTOR complex 2, Cancer research, biology.protein, Cytokines, Female, BMSCs, Developmental Biology, Research Paper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e6dab908d4ef2a95fa0e6d142e3353
http://europepmc.org/articles/PMC6775318

المؤلفون: Nicolas Bisson, Frédérick A. Mallette, Laurence M. Gagné, Marc-Étienne Huot, Jean-Philippe Lambert, Nadine Morin, Noémie Lavoie

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: PTM, post-translational modification, mTORC1, Biochemistry, mTORC2, chemistry.chemical_compound, 0302 clinical medicine, EPHB2, Phosphorylation, CIP, calf intestinal alkaline phosphatase, 0303 health sciences, biology, mTOR, mechanistic target of rapamycin, TOR Serine-Threonine Kinases, mTORC2, mTOR complex 2, Intracellular Signaling Peptides and Proteins, IP, immunoprecipitation, 3. Good health, Cell biology, 030220 oncology & carcinogenesis, mTOR, Research Article, Signal Transduction, Fer, Feline sarcoma–related protein, DEPTOR, FRQS, Fonds de Recherche du Québec—Santé, R-2HG, R-2-hydroxyglutarate, SYK, spleen tyrosine kinase, 03 medical and health sciences, Humans, Molecular Biology, Protein kinase B, Mechanistic target of rapamycin, PI3K/AKT/mTOR pathway, 030304 developmental biology, tyrosine phosphorylation, EPH, erythropoietin-producing hepatocellular carcinoma, Tyrosine phosphorylation, Cell Biology, Tyr, tyrosine, PTEN, phosphatase and tensin homolog, HEK293 Cells, chemistry, biology.protein, β-TRCP1, β-transducin repeat–containing protein 1, Tyrosine, mTORC1, mTOR complex 1, Protein Processing, Post-Translational, HA, hemagglutinin, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f12996bbcdf1e104173be833b69be78
http://europepmc.org/articles/PMC8551655

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المؤلفون: Fengwen Xie, Li Chen, Qun Wang, Xiang Zhong, Zhixing Liu

المصدر: Molecular Medicine Reports

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Angiogenesis, Cell Survival, Receptor for Advanced Glycation End Products, Apoptosis, Mechanistic Target of Rapamycin Complex 2, neointimal hyperplasia, Biochemistry, mTORC2, RAGE (receptor), 03 medical and health sciences, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, Genetics, medicine, Human Umbilical Vein Endothelial Cells, Calgranulin B, Humans, Calgranulin A, Viability assay, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, Cell Proliferation, Neointimal hyperplasia, Inflammation, Sirolimus, Chemistry, TOR Serine-Threonine Kinases, Endothelial Cells, Articles, medicine.disease, Cell biology, S100 protein, Endothelial stem cell, 030104 developmental biology, Oncology, mTOR complex 2, 030220 oncology & carcinogenesis, endothelial cell, mTOR, Molecular Medicine, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::540f8864f8dc637db345e6766262b23f
https://pubmed.ncbi.nlm.nih.gov/33174028

المؤلفون: Shenglei Li, Yandan Ren, Fanghua Gong, Mengyin Zhang, Wen Zhao, Xiao-Jing Shi, Guiqin Hou, Zhaoming Lu, Yang Wang, Bin Yu, Jianying Zhang, Yan Li

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 6, Pp 1004-1019 (2020)

مصطلحات موضوعية: Original article, Cell cycle checkpoint, AKT, protein kinase B (PKB), IC50, half maximal inhibitory concentration, mTORC1, mTOR, mammalian target of rapamycin, pp242, medicine.disease_cause, mTORC2, TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling, 4EBP-1, E binding protein-1, 03 medical and health sciences, 0302 clinical medicine, PI3K, phosphatidylinositol 3 kinase, In vivo, Esophageal squamous cell carcinoma, Medicine, General Pharmacology, Toxicology and Pharmaceutics, Protein kinase B, RAD001, 030304 developmental biology, 0303 health sciences, business.industry, H&E staining, hematoxylin and eosin staining, AKT, lcsh:RM1-950, mTORC2, mTOR complex 2, rapalogs, rapamycin and its analogs, TNM, tumor-node-metastasis, FDA, U.S. Food and Drug Administration, lcsh:Therapeutics. Pharmacology, RICTOR, rapamycin-insensitive companion of mTOR, Apoptosis, 030220 oncology & carcinogenesis, Cancer research, Phosphorylation, p70S6K, p70 ribosomal S6 kinase-1, ESCC, esophageal squamous cell carcinoma, mTORC1, mTOR complex 1, business, Carcinogenesis, RICTOR

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c1b59250e93bdc4a29506776673a67
https://pubmed.ncbi.nlm.nih.gov/32642408