المؤلفون: Menghao Huang, Kushan Chowdhury, Zhigang Fang, X. Charlie Dong, Ming O. Li, Suthat Liangpunsakul, Hyeong-Geug Kim

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 921-942 (2021)
Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: 0301 basic medicine, Sestrins, MPO, myeloperoxidase, Mitogen-Activated Protein Kinase Kinase 7, RC799-869, DMSO, dimethyl sulfoxide, FoxO, forkhead box O, Sesn1/2/3, sestrin1/2/3, medicine.disease_cause, TKO, triple knockout, Mice, PCR, polymerase chain reaction, 0302 clinical medicine, GSH, glutathione, Phosphorylation, NF-κB, nuclear factor kappa B, Original Research, Cat, catalase, Mice, Knockout, Sestrin, Gpx3, glutathione peroxidase 3, Il6, interleukin 6, WD, Western diet, biology, Chemistry, Kinase, Fatty liver, Tgfbr1, transforming growth factor beta receptor 1, Gastroenterology, Col1a1, collagen type 1 alpha 1, Nox1, NADPH oxidase 1, Diseases of the digestive system. Gastroenterology, Dgat2, diacylglycerol O-acyltransferase 2, Cell biology, Keap1, Kelch-like ECH-associated protein 1, C-Jun N-Terminal Kinase, Liver, Lipotoxicity, c-Jun N-terminal kinases, JNK, c-Jun N-terminal kinase, 030211 gastroenterology & hepatology, Disease Susceptibility, Signal transduction, NASH, nonalcoholic steatohepatitis, Gss, glutathione synthetase, Pdgfrb, platelet-derived growth factor receptor beta, Timp1, tissue inhibitor of metalloproteinase 1, Fasn, fatty acid synthase, Fatty Liver Disease, Sod, superoxide dismutase, Acta2, smooth muscle actin alpha 2, ER, endoplasmic reticulum, PA, palmitic acid, 03 medical and health sciences, 4-HNE, 4-hydroxynonenal, MKK, mitogen-activated protein kinase kinase, medicine, Animals, Humans, Srebp, sterol regulatory element-binding protein, Protein kinase A, KD, knockdown, MDA, malondialdehyde, Inflammation, KO, knockout, Hepatology, NRF2, nuclear factor erythroid 2-related like 2, JNK Mitogen-Activated Protein Kinases, Lipid Metabolism, medicine.disease, Tgfb1, transforming growth factor beta 1, WT, wild-type, mTORC, mechanistic target of rapamycin complex, Fatty Liver, AMPK, AMP-activated protein kinase, Disease Models, Animal, Oxidative Stress, Scd1, stearoyl-CoA desaturase 1, 030104 developmental biology, Gene Expression Regulation, Cytoprotection, Hepatocytes, biology.protein, BSA, bovine serum albumin, SD, standard deviation, DHE, dihydroethidium, PERK, protein kinase R-like endoplasmic reticulum kinase, Tnf, tumor necrosis factor, Biomarkers, Oxidative stress

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1574bc0f082fa7f7fd23bf88f6f9c6fc
http://www.sciencedirect.com/science/article/pii/S2352345X21000862

المؤلفون: Paul M. Titchenell, Dominic Santoleri

المصدر: Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: 0301 basic medicine, Anabolism, medicine.medical_treatment, LIRKO, liver insulin resistant knockout mice, Review, PI3K, phosphoinositide-3-phosphate kinase, 0302 clinical medicine, Gck, glucokinase, PI3K/Akt Signaling Pathway, Insulin, biology, Gastroenterology, De Novo Lipogenesis, IRS, insulin-receptor substrate, Liver, Lipogenesis, 030211 gastroenterology & hepatology, Signal Transduction, medicine.medical_specialty, TAG, triacylglycerol, HGP, hepatic glucose production, Models, Biological, 03 medical and health sciences, Insulin resistance, Hepatic Glucose Production, Internal medicine, FFA, free fatty acid, GSK3, glycogen synthase kinase 3, medicine, Animals, Humans, SCAP, SREBP cleavage-activating protein, SREBP1c, sterol regulatory element binding protein 1c, T2DM, type II diabetes mellitus, GYS2, glycogen synthase, Hepatology, business.industry, Insulin Signaling, Hypertriglyceridemia, VLDL, very-low-density lipoprotein, ChREBP, carbohydrate response element binding protein, Lipid metabolism, Metabolism, Lipid Metabolism, medicine.disease, PTEN, phosphatase and tensin homolog, mTORC, mechanistic target of rapamycin complex, Insulin receptor, Hepatic Insulin Resistance, 030104 developmental biology, Endocrinology, biology.protein, NAFLD, nonalcoholic fatty liver disease, Insulin Resistance, TSC, tuberous sclerosis complex, business, PIP3, phosphatidylinositol (3,4,5)-trisphosphate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27eb16d2a993c3fec511936ebd4c8dd
https://doi.org/10.1016/j.jcmgh.2018.10.016

المؤلفون: Vorotnikov AV; Faculty of Fundamental Medicine, M.V. Lomonosov Moscow State University, Moscow, Russian Federation.; Institute of Experimental Cardiology, Russian Cardiology Research and Production Complex, Moscow, Russian Federation., Tyurin-Kuzmin PA; Faculty of Fundamental Medicine, M.V. Lomonosov Moscow State University, Moscow, Russian Federation.

المصدر: Genes & diseases [Genes Dis] 2014 Sep 28; Vol. 1 (2), pp. 162-173. Date of Electronic Publication: 2014 Sep 28 (Print Publication: 2014).

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier B.V. on behalf of KeAi Communications Co. Ltd Country of Publication: Netherlands NLM ID: 101635967 Publication Model: eCollection Cited Medium: Internet ISSN: 2352-3042 (Electronic) Linking ISSN: 23523042 NLM ISO Abbreviation: Genes Dis Subsets: PubMed not MEDLINE