المؤلفون: Yamamuro-Tanabe A; Laboratory of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotoge-cho, Hirakata, Osaka, 573-0101, Japan., Oshima Y; Laboratory of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotoge-cho, Hirakata, Osaka, 573-0101, Japan., Iyama T; Laboratory of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotoge-cho, Hirakata, Osaka, 573-0101, Japan., Ishimaru Y; Laboratory of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotoge-cho, Hirakata, Osaka, 573-0101, Japan., Yoshioka Y; Laboratory of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotoge-cho, Hirakata, Osaka, 573-0101, Japan. Electronic address: yoshioka@pharm.setsunan.ac.jp.

المصدر: Journal of pharmacological sciences [J Pharmacol Sci] 2024 Jun; Vol. 155 (2), pp. 52-62. Date of Electronic Publication: 2024 Mar 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Japanese Pharmacological Society Country of Publication: Japan NLM ID: 101167001 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1347-8648 (Electronic) Linking ISSN: 13478613 NLM ISO Abbreviation: J Pharmacol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Apoptosis*/drug effects , Apoptosis*/genetics , Proteasome Inhibitors*/pharmacology , Superoxides*/metabolism , Neuroblastoma*/pathology , Neuroblastoma*/metabolism , Leupeptins*/pharmacology , NADPH Oxidases*/metabolism , NADPH Oxidases*/genetics , NADPH Oxidase 5*/genetics , NADPH Oxidase 5*/metabolism, Humans ; Cell Line, Tumor ; Antioxidants/pharmacology ; Dose-Response Relationship, Drug ; Acetylcysteine/pharmacology ; Neurons/metabolism ; Neurons/drug effects

المؤلفون: Wu S; Cellular and Molecular Biology Laboratory, Affiliated Zhoushan Hospital of Wenzhou Medical University, Zhoushan, Zhejiang 316020, P.R. China., Zhao Q; Cellular and Molecular Biology Laboratory, Affiliated Zhoushan Hospital of Wenzhou Medical University, Zhoushan, Zhejiang 316020, P.R. China., Liu S; Cellular and Molecular Biology Laboratory, Affiliated Zhoushan Hospital of Wenzhou Medical University, Zhoushan, Zhejiang 316020, P.R. China., Kuang J; Cancer and Anticancer Drug Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China., Zhang J; Cancer and Anticancer Drug Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China., Onga A; Cancer and Anticancer Drug Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China., Shen Y; Cancer and Anticancer Drug Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China., Wang J; Cancer and Anticancer Drug Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China., Sui H; Cancer and Anticancer Drug Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China., Ni L; Cancer and Anticancer Drug Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China., Ye Y; Cancer and Anticancer Drug Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China., Tu X; Cancer and Anticancer Drug Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China., Le HB; Cellular and Molecular Biology Laboratory, Affiliated Zhoushan Hospital of Wenzhou Medical University, Zhoushan, Zhejiang 316020, P.R. China., Zheng Y; Department of General Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China., Cui R; Cellular and Molecular Biology Laboratory, Affiliated Zhoushan Hospital of Wenzhou Medical University, Zhoushan, Zhejiang 316020, P.R. China., Zhu W; Cellular and Molecular Biology Laboratory, Affiliated Zhoushan Hospital of Wenzhou Medical University, Zhoushan, Zhejiang 316020, P.R. China.

المصدر: International journal of oncology [Int J Oncol] 2024 Aug; Vol. 65 (2). Date of Electronic Publication: 2024 Jun 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: D.A. Spandidos Country of Publication: Greece NLM ID: 9306042 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1791-2423 (Electronic) Linking ISSN: 10196439 NLM ISO Abbreviation: Int J Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Cisplatin*/pharmacology , Cisplatin*/therapeutic use , Glucosides*/pharmacology , Glucosides*/therapeutic use , Carcinoma, Non-Small-Cell Lung*/drug therapy , Carcinoma, Non-Small-Cell Lung*/pathology , Carcinoma, Non-Small-Cell Lung*/metabolism , Stilbenes*/pharmacology , Stilbenes*/therapeutic use , Drug Synergism* , Lung Neoplasms*/drug therapy , Lung Neoplasms*/pathology , Lung Neoplasms*/metabolism , Oxidative Stress*/drug effects , Xenograft Model Antitumor Assays* , Reactive Oxygen Species*/metabolism , NADPH Oxidase 5*, Animals ; Humans ; Mice ; Cell Line, Tumor ; Apoptosis/drug effects ; A549 Cells ; Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Cell Proliferation/drug effects ; Endoplasmic Reticulum Stress/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Male

المؤلفون: Cui C; Department of Structural Biology, St Jude Children's Research Hospital, Memphis, TN38105, USA., Jiang M; Department of Structural Biology, St Jude Children's Research Hospital, Memphis, TN38105, USA., Jain N; Department of Structural Biology, St Jude Children's Research Hospital, Memphis, TN38105, USA., Das S; Department of Chemical Biology & Therapeutics, St Jude Children's Research Hospital, Memphis, TN38105, USA., Lo YH; Department of Structural Biology, St Jude Children's Research Hospital, Memphis, TN38105, USA., Kermani AA; Department of Structural Biology, St Jude Children's Research Hospital, Memphis, TN38105, USA., Pipatpolkai T; Division of Physics and Applied Physics, School of Physical and Mathematical Sciences, Nanyang Technological University, 673371, Singapore, Singapore. tanadet.pipatpolkai@ntu.edu.sg., Sun J; Department of Structural Biology, St Jude Children's Research Hospital, Memphis, TN38105, USA. ji.sun@stjude.org.

المصدر: Nature communications [Nat Commun] 2024 May 11; Vol. 15 (1), pp. 3994. Date of Electronic Publication: 2024 May 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Calcium*/metabolism , NADP*/metabolism , NADPH Oxidase 5*/metabolism , NADPH Oxidase 5*/genetics , NADPH Oxidase 5*/chemistry, Humans ; Binding Sites ; Cryoelectron Microscopy ; Electron Transport ; Enzyme Activation ; Flavin-Adenine Dinucleotide/metabolism ; Molecular Dynamics Simulation ; Protein Binding ; Reactive Oxygen Species/metabolism ; Superoxides/metabolism ; Zinc/metabolism

المؤلفون: Steinmetz EL; Zoology & Physiology, ZHMB (Center of Human and Molecular Biology), Saarland University, Building B2.1, D-66123 Saarbrücken, Germany., Scherer A; Zoology & Physiology, ZHMB (Center of Human and Molecular Biology), Saarland University, Building B2.1, D-66123 Saarbrücken, Germany., Calvet C; Zoology & Physiology, ZHMB (Center of Human and Molecular Biology), Saarland University, Building B2.1, D-66123 Saarbrücken, Germany., Müller U; Zoology & Physiology, ZHMB (Center of Human and Molecular Biology), Saarland University, Building B2.1, D-66123 Saarbrücken, Germany.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 02; Vol. 25 (11). Date of Electronic Publication: 2024 Jun 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Drosophila melanogaster*/genetics , Superoxide Dismutase*/metabolism , Superoxide Dismutase*/genetics , Reactive Oxygen Species*/metabolism , Drosophila Proteins*/metabolism , Drosophila Proteins*/genetics , Ovary*/metabolism, Animals ; Female ; NADPH Oxidases/metabolism ; NADPH Oxidases/genetics ; Reproduction ; NADPH Oxidase 5/metabolism ; NADPH Oxidase 5/genetics ; Oviposition ; Chorion/metabolism

المؤلفون: Jiang Z; Department of Pathology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Pathology, De Boelelaan 1117, Amsterdam, the Netherlands; Amsterdam Cardiovascular Sciences, Microcirculation, Amsterdam, the Netherlands. Electronic address: z.jiang@amsterdamumc.nl., Wu L; Department of Pathology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Pathology, De Boelelaan 1117, Amsterdam, the Netherlands; Amsterdam Cardiovascular Sciences, Microcirculation, Amsterdam, the Netherlands., van der Leeden B; Department of Pathology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Pathology, De Boelelaan 1117, Amsterdam, the Netherlands; Amsterdam Institute for Infection and Immunity, AUMC, Location VUmc, Amsterdam, the Netherlands., van Rossum AC; Amsterdam Cardiovascular Sciences, Microcirculation, Amsterdam, the Netherlands; Department of Cardiology, AUMC, location VUmc, Amsterdam, the Netherlands., Niessen HWM; Department of Pathology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Pathology, De Boelelaan 1117, Amsterdam, the Netherlands; Amsterdam Cardiovascular Sciences, Microcirculation, Amsterdam, the Netherlands; Department of Cardiac Surgery, AUMC, Location AMC and VUmc, Amsterdam, the Netherlands., Krijnen PAJ; Department of Pathology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Pathology, De Boelelaan 1117, Amsterdam, the Netherlands; Amsterdam Cardiovascular Sciences, Microcirculation, Amsterdam, the Netherlands.

المصدر: International journal of cardiology [Int J Cardiol] 2023 Jan 01; Vol. 370, pp. 454-462. Date of Electronic Publication: 2022 Nov 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8200291 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1874-1754 (Electronic) Linking ISSN: 01675273 NLM ISO Abbreviation: Int J Cardiol Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19*/metabolism , NADPH Oxidase 5*/metabolism , NADPH Oxidase 2*/metabolism, Humans ; Endothelium, Vascular/metabolism ; Heart ; Reactive Oxygen Species/metabolism

المؤلفون: Keshtgar S; Department of Physiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran., Ghani E; Endocrinology and Metabolism Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.; Department of Physiology, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

المصدر: Andrologia [Andrologia] 2022 Sep; Vol. 54 (8), pp. e14470. Date of Electronic Publication: 2022 Jun 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Blackwell Pub Country of Publication: Germany NLM ID: 0423506 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-0272 (Electronic) Linking ISSN: 03034569 NLM ISO Abbreviation: Andrologia Subsets: MEDLINE

مواضيع طبية MeSH: Calcium*/metabolism , NADPH Oxidase 5*/genetics , NADPH Oxidase 5*/metabolism , Reactive Oxygen Species*/metabolism , Spermatozoa*/drug effects , Spermatozoa*/metabolism, Calcimycin/pharmacology ; Humans ; Male ; Semen/drug effects ; Semen/metabolism ; Sperm Motility/drug effects ; Sperm Motility/genetics ; Sperm Motility/physiology

المؤلفون: Ho F; Department of Diabetes, Central Clinical School, Monash University, 99 Commercial Road, Melbourne, VIC, 3004, Australia., Watson AMD; Department of Diabetes, Central Clinical School, Monash University, 99 Commercial Road, Melbourne, VIC, 3004, Australia.; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, 75 commercial Road, Melbourne, VIC, 3004, Australia., Elbatreek MH; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Zagazig University, Zagazig, 44519, Egypt. melbatreek@ppmlab.net.; Department of Pharmacology and Personalised Medicine, MeHNS, Faculty of Health, Medicine & Life Science, Maastricht University, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands. melbatreek@ppmlab.net., Kleikers PWM; Department of Pharmacology and Personalised Medicine, MeHNS, Faculty of Health, Medicine & Life Science, Maastricht University, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands., Khan W; Department of Diabetes, Central Clinical School, Monash University, 99 Commercial Road, Melbourne, VIC, 3004, Australia., Sourris KC; Department of Diabetes, Central Clinical School, Monash University, 99 Commercial Road, Melbourne, VIC, 3004, Australia., Dai A; Department of Diabetes, Central Clinical School, Monash University, 99 Commercial Road, Melbourne, VIC, 3004, Australia., Jha J; Department of Diabetes, Central Clinical School, Monash University, 99 Commercial Road, Melbourne, VIC, 3004, Australia., Schmidt HHHW; Department of Pharmacology and Personalised Medicine, MeHNS, Faculty of Health, Medicine & Life Science, Maastricht University, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands. hschmidt@ppmlab.net., Jandeleit-Dahm KAM; Department of Diabetes, Central Clinical School, Monash University, 99 Commercial Road, Melbourne, VIC, 3004, Australia. karin.jandeleit-dahm@monash.edu.; Institute for Clinical Diabetology, German Diabetes Centre, Leibniz Centre for Diabetes Research at Heinrich Heine University Düsseldorf, Auf'm Hennekamp 65, 40225, Düsseldorf, Germany. karin.jandeleit-dahm@monash.edu.

المصدر: Scientific reports [Sci Rep] 2022 Jul 07; Vol. 12 (1), pp. 11570. Date of Electronic Publication: 2022 Jul 07.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Aortic Aneurysm, Abdominal* , Atherosclerosis*/metabolism , Diabetes Mellitus* , NADPH Oxidase 5*/metabolism, Animals ; Disease Models, Animal ; Endothelial Cells/metabolism ; Mice ; Mice, Knockout, ApoE ; Oxygen ; Reactive Oxygen Species/metabolism

المؤلفون: Cortés A; Department of Biochemistry and Genetics, University of Navarra, Pamplona, Spain.; Navarra Institute for Health Research (IdiSNA), Pamplona, Spain., Marqués J; Department of Biochemistry and Genetics, University of Navarra, Pamplona, Spain.; Navarra Institute for Health Research (IdiSNA), Pamplona, Spain., Pejenaute Á; Department of Biochemistry and Genetics, University of Navarra, Pamplona, Spain.; Navarra Institute for Health Research (IdiSNA), Pamplona, Spain., Ainzúa E; Department of Biochemistry and Genetics, University of Navarra, Pamplona, Spain.; Navarra Institute for Health Research (IdiSNA), Pamplona, Spain., Ansorena E; Department of Biochemistry and Genetics, University of Navarra, Pamplona, Spain.; Navarra Institute for Health Research (IdiSNA), Pamplona, Spain., Abizanda G; Navarra Institute for Health Research (IdiSNA), Pamplona, Spain.; Hematology Service, Clínica Universidad de Navarra, University of Navarra, Pamplona, Spain., Prósper F; Navarra Institute for Health Research (IdiSNA), Pamplona, Spain.; Hematology Service, Clínica Universidad de Navarra, University of Navarra, Pamplona, Spain.; CIBERONC, Madrid, Spain., de Miguel C; Department of Biochemistry and Genetics, University of Navarra, Pamplona, Spain.; Navarra Institute for Health Research (IdiSNA), Pamplona, Spain., Zalba G; Department of Biochemistry and Genetics, University of Navarra, Pamplona, Spain. gzalba@unav.es.; Navarra Institute for Health Research (IdiSNA), Pamplona, Spain. gzalba@unav.es.

المصدر: Journal of physiology and biochemistry [J Physiol Biochem] 2023 Nov; Vol. 79 (4), pp. 787-797. Date of Electronic Publication: 2023 Aug 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Servicio de Publicaciones de la Universidad De Navarra (departamentos de fisiología y nutrición y de bioquimica) Country of Publication: Spain NLM ID: 9812509 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1877-8755 (Electronic) Linking ISSN: 11387548 NLM ISO Abbreviation: J Physiol Biochem Subsets: MEDLINE

مواضيع طبية MeSH: Proto-Oncogene Proteins c-akt* , Myocardial Infarction*/genetics, Mice ; Animals ; NADPH Oxidase 5/genetics ; NADPH Oxidase 5/metabolism ; Reactive Oxygen Species/metabolism ; NADPH Oxidases/genetics ; NADPH Oxidases/metabolism ; RNA, Messenger ; Proto-Oncogene Proteins c-bcl-2

المؤلفون: Szeles Z; Department of Physiology, Faculty of Medicine, Semmelweis University, PO Box 259, 1444, Budapest, Hungary., Petheő GL; Department of Physiology, Faculty of Medicine, Semmelweis University, PO Box 259, 1444, Budapest, Hungary., Szikora B; ImmunoGenes Ltd., Budakeszi, Hungary., Kacskovics I; ImmunoGenes Ltd., Budakeszi, Hungary., Geiszt M; Department of Physiology, Faculty of Medicine, Semmelweis University, PO Box 259, 1444, Budapest, Hungary. geiszt.miklos@med.semmelweis-univ.hu.

المصدر: Scientific reports [Sci Rep] 2023 Oct 11; Vol. 13 (1), pp. 17174. Date of Electronic Publication: 2023 Oct 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Membrane Proteins*/metabolism , Antibodies, Monoclonal*, Animals ; Female ; Humans ; Male ; NADPH Oxidase 5 ; Endothelial Cells/metabolism ; Spleen/metabolism ; Testis/metabolism ; NADPH Oxidases/genetics ; NADPH Oxidases/metabolism ; Reactive Oxygen Species/metabolism ; Mammals/metabolism

المؤلفون: da Silva JF; Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo (FMRP-USP)- USP, Brazil., Alves JV; Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo (FMRP-USP)- USP, Brazil., Silva-Neto JA; Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo (FMRP-USP)- USP, Brazil., Costa RM; Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo (FMRP-USP)- USP, Brazil., Neves KB; Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Centre, University of Glasgow, Glasgow, U.K., Alves-Lopes R; Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Centre, University of Glasgow, Glasgow, U.K., Carmargo LL; Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Centre, University of Glasgow, Glasgow, U.K., Rios FJ; Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Centre, University of Glasgow, Glasgow, U.K., Montezano AC; Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Centre, University of Glasgow, Glasgow, U.K., Touyz RM; Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Centre, University of Glasgow, Glasgow, U.K., Tostes RC; Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo (FMRP-USP)- USP, Brazil.

المصدر: Clinical science (London, England : 1979) [Clin Sci (Lond)] 2021 Aug 13; Vol. 135 (15), pp. 1845-1858.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Portland Press on behalf of the Medical Research Society and the Biochemical Society Country of Publication: England NLM ID: 7905731 Publication Model: Print Cited Medium: Internet ISSN: 1470-8736 (Electronic) Linking ISSN: 01435221 NLM ISO Abbreviation: Clin Sci (Lond) Subsets: MEDLINE

مواضيع طبية MeSH: Atherosclerosis/*enzymology , Endothelial Cells/*drug effects , Lysophosphatidylcholines/*toxicity , NADPH Oxidase 5/*metabolism , Oxidative Stress/*drug effects , Reactive Oxygen Species/*metabolism, Atherosclerosis/pathology ; Calcium/metabolism ; Calcium Signaling ; Cell Adhesion ; Cells, Cultured ; Coculture Techniques ; Endothelial Cells/enzymology ; Endothelial Cells/pathology ; Enzyme Activation ; Enzyme Inhibitors/pharmacology ; Humans ; Intercellular Adhesion Molecule-1/genetics ; Intercellular Adhesion Molecule-1/metabolism ; Monocytes/metabolism ; NADPH Oxidase 5/antagonists & inhibitors ; NADPH Oxidase 5/genetics ; RNA Interference