المؤلفون: Blum NK; Institut für Pharmakologie und Toxikologie, Universitätsklinikum Jena, Friedrich-Schiller-Universität Jena, Drackendorfer Str. 1, D-07747, Jena, Germany., Schaffner A; Institut für Pharmakologie und Toxikologie, Universitätsklinikum Jena, Friedrich-Schiller-Universität Jena, Drackendorfer Str. 1, D-07747, Jena, Germany., Drube J; Institut für Molekulare Zellbiologie, CMB - Center for Molecular Biomedicine, Universitätsklinikum Jena, Friedrich-Schiller-Universität Jena, Hans-Knöll-Str. 2, D-07745, Jena, Germany., Nagel F; 7TM Antibodies GmbH, Hans-Knöll-Str. 6, D-07745, Jena, Germany., Reinscheid RK; Institut für Pharmakologie und Toxikologie, Universitätsklinikum Jena, Friedrich-Schiller-Universität Jena, Drackendorfer Str. 1, D-07747, Jena, Germany., Hoffmann C; Institut für Molekulare Zellbiologie, CMB - Center for Molecular Biomedicine, Universitätsklinikum Jena, Friedrich-Schiller-Universität Jena, Hans-Knöll-Str. 2, D-07745, Jena, Germany., Schulz S; Institut für Pharmakologie und Toxikologie, Universitätsklinikum Jena, Friedrich-Schiller-Universität Jena, Drackendorfer Str. 1, D-07747, Jena, Germany; 7TM Antibodies GmbH, Hans-Knöll-Str. 6, D-07745, Jena, Germany. Electronic address: stefan.schulz@med.uni-jena.de.

المصدر: European journal of pharmacology [Eur J Pharmacol] 2024 Jun 15; Vol. 973, pp. 176587. Date of Electronic Publication: 2024 Apr 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Neurokinin-1*/metabolism , Receptors, Neurokinin-1*/agonists , Substance P*/pharmacology, Phosphorylation/drug effects ; Humans ; Animals ; Immunoassay/methods ; Cricetulus ; CHO Cells ; Mice ; Neurokinin-1 Receptor Antagonists/pharmacology ; Neurokinin A/pharmacology ; Neurokinin A/metabolism

المؤلفون: Yang Y; Institute of Digestive Endoscopy and Medical Center for Digestive Diseases, Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China., Cao X; Institute of Digestive Endoscopy and Medical Center for Digestive Diseases, Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China., Wang Y; Institute of Digestive Endoscopy and Medical Center for Digestive Diseases, Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China., Wu X; Institute of Digestive Endoscopy and Medical Center for Digestive Diseases, Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China., Zhou P; Lab Center, Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu, China., Miao L; Institute of Digestive Endoscopy and Medical Center for Digestive Diseases, Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China., Deng X; Institute of Digestive Endoscopy and Medical Center for Digestive Diseases, Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.

المصدر: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2024 Jul; Vol. 44 (7), pp. 1651-1667. Date of Electronic Publication: 2024 Mar 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101160857 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-3231 (Electronic) Linking ISSN: 14783223 NLM ISO Abbreviation: Liver Int Subsets: MEDLINE

مواضيع طبية MeSH: Aprepitant*/pharmacology , Aprepitant*/therapeutic use , Autophagy*/drug effects , Apoptosis*/drug effects , Cholangiocarcinoma*/drug therapy , Cholangiocarcinoma*/pathology , Cholangiocarcinoma*/metabolism , Reactive Oxygen Species*/metabolism , Mice, Nude* , Mice, Inbred BALB C* , Bile Duct Neoplasms*/drug therapy , Bile Duct Neoplasms*/pathology , Bile Duct Neoplasms*/metabolism , Xenograft Model Antitumor Assays* , Neurokinin-1 Receptor Antagonists*/pharmacology, Animals ; Humans ; Cell Line, Tumor ; Mice ; Male ; Female ; Receptors, Neurokinin-1/metabolism ; Middle Aged ; Cell Proliferation/drug effects

المؤلفون: Carlton-Carew SRE; Vascular Biology Section, Cardiovascular & Genomics Research Institute, St. George's, University of London, London, UK., Greenberg HZE; Vascular Biology Section, Cardiovascular & Genomics Research Institute, St. George's, University of London, London, UK., Greenwood IA; Vascular Biology Section, Cardiovascular & Genomics Research Institute, St. George's, University of London, London, UK., Albert AP; Vascular Biology Section, Cardiovascular & Genomics Research Institute, St. George's, University of London, London, UK.

المصدر: Physiological reports [Physiol Rep] 2024 Jun; Vol. 12 (12), pp. e16125.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society Country of Publication: United States NLM ID: 101607800 Publication Model: Print Cited Medium: Internet ISSN: 2051-817X (Electronic) Linking ISSN: 2051817X NLM ISO Abbreviation: Physiol Rep Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Calcium-Sensing*/metabolism , Calcitonin Gene-Related Peptide*/metabolism , Calcitonin Gene-Related Peptide*/pharmacology , Receptors, Neurokinin-1*/metabolism , Mesenteric Arteries*/drug effects , Mesenteric Arteries*/physiology , Mesenteric Arteries*/metabolism , Vasodilation*/drug effects , Vasodilation*/physiology, Animals ; Male ; Rats ; Rats, Wistar ; Neurokinin-1 Receptor Antagonists/pharmacology ; Calcium/metabolism ; Capsaicin/pharmacology ; Calcitonin Gene-Related Peptide Receptor Antagonists/pharmacology ; Signal Transduction/physiology

المؤلفون: Bom AOP; Laboratory of Pathophysiology, Butantan Institute, São Paulo 05503-900, SP, Brazil.; Postgraduate Program in Toxinology, Butantan Institute, São Paulo 05503-900, SP, Brazil., Dias-Soares M; Laboratory of Pathophysiology, Butantan Institute, São Paulo 05503-900, SP, Brazil., Corrêa RCD; Laboratory of Pathophysiology, Butantan Institute, São Paulo 05503-900, SP, Brazil.; Postgraduate Program in Toxinology, Butantan Institute, São Paulo 05503-900, SP, Brazil., Neves CL; Laboratory of Pathophysiology, Butantan Institute, São Paulo 05503-900, SP, Brazil., Hosch NG; Laboratory of Pain and Signaling, Butantan Institute, São Paulo 05503-900, SP, Brazil., Lucena GG; Laboratory of Pathophysiology, Butantan Institute, São Paulo 05503-900, SP, Brazil., Oliveira CG; Laboratory of Functional Neuroanatomy of Pain, Institute of Biomedical Sciences, University of Sao Paulo, São Paulo 05508-900, SP, Brazil., Pagano RL; Laboratory of Neuroscience, Hospital Sírio-Libanês, São Paulo 01308-060, SP, Brazil., Chacur M; Laboratory of Functional Neuroanatomy of Pain, Institute of Biomedical Sciences, University of Sao Paulo, São Paulo 05508-900, SP, Brazil., Giorgi R; Laboratory of Pathophysiology, Butantan Institute, São Paulo 05503-900, SP, Brazil.

المصدر: Toxins [Toxins (Basel)] 2024 Apr 10; Vol. 16 (4). Date of Electronic Publication: 2024 Apr 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101530765 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6651 (Electronic) Linking ISSN: 20726651 NLM ISO Abbreviation: Toxins (Basel) Subsets: MEDLINE

مواضيع طبية MeSH: Hyperalgesia*/chemically induced , Hyperalgesia*/metabolism , Bothrops* , Crotalid Venoms*/toxicity , Ganglia, Spinal*/drug effects , Ganglia, Spinal*/metabolism , Receptors, Neurokinin-1*/metabolism, Animals ; Male ; Minocycline/pharmacology ; Spinal Cord/drug effects ; Spinal Cord/metabolism ; Early Growth Response Protein 1/metabolism ; Early Growth Response Protein 1/genetics ; Microglia/drug effects ; Microglia/metabolism ; Neuroglia/drug effects ; Neuroglia/metabolism ; Rats ; Glial Fibrillary Acidic Protein/metabolism ; Calcium-Binding Proteins/metabolism ; Astrocytes/drug effects ; Astrocytes/metabolism ; Microfilament Proteins/metabolism ; Neurokinin-1 Receptor Antagonists/pharmacology ; Rats, Sprague-Dawley

عنوان ترانسليتريتد: 神经激肽1受体拮抗剂的研究与应用进展.

المؤلفون: Hong X; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China., Ma J; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China., Zheng S; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China., Zhao G; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China., Fu C; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China. fucy03@zstu.edu.cn.

المصدر: Journal of Zhejiang University. Science. B [J Zhejiang Univ Sci B] 2024 Feb 15; Vol. 25 (2), pp. 91-105.

نوع المنشور: Review; Journal Article

بيانات الدورية: Publisher: Zhejiang University Press Country of Publication: China NLM ID: 101236535 Publication Model: Print Cited Medium: Internet ISSN: 1862-1783 (Electronic) Linking ISSN: 16731581 NLM ISO Abbreviation: J Zhejiang Univ Sci B Subsets: MEDLINE

مواضيع طبية MeSH: Neurokinin-1 Receptor Antagonists*/pharmacology , Neurokinin-1 Receptor Antagonists*/therapeutic use , Neoplasms*/drug therapy, Humans ; Quality of Life ; Substance P ; Receptors, Neurokinin-1

المؤلفون: Madsen JJ; Global and Planetary Health, College of Public Health, University of South Florida, Tampa, Florida, USA; Center for Global Health and Infectious Diseases Research, College of Public Health, University of South Florida, Tampa, Florida, USA; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA., Petersen JE; Section for Metabolic Receptology, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark., Christensen DP; Embark Biotech ApS, Copenhagen, Denmark., Hansen JB; Embark Biotech ApS, Copenhagen, Denmark., Schwartz TW; Section for Metabolic Receptology, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark., Frimurer TM; Section for Metabolic Receptology, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark., Olsen OH; Section for Metabolic Receptology, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark. Electronic address: oho@sund.ku.dk.

المصدر: The Journal of biological chemistry [J Biol Chem] 2023 Dec; Vol. 299 (12), pp. 105438. Date of Electronic Publication: 2023 Nov 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Neurokinin-1*/agonists , Receptors, Neurokinin-1*/metabolism , Tachykinins*/metabolism, Animals ; Humans ; Cell Line ; Chlorocebus aethiops ; Ligands ; Neurokinin A/metabolism ; Neurokinin-1 Receptor Antagonists ; Substance P ; Receptors, Neurokinin-2/metabolism

المؤلفون: Furdui A; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, Ontario, Canada.; Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., da Silveira Scarpellini C; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, Ontario, Canada., Montandon G; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, Ontario, Canada.; Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.; Division of Respirology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

المصدر: Journal of neurophysiology [J Neurophysiol] 2024 Jul 01; Vol. 132 (1), pp. 108-129. Date of Electronic Publication: 2024 May 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Physiological Society Country of Publication: United States NLM ID: 0375404 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1598 (Electronic) Linking ISSN: 00223077 NLM ISO Abbreviation: J Neurophysiol Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Opioid, mu*/metabolism , Receptors, Opioid, mu*/genetics , Receptors, Neurokinin-1*/metabolism , Receptors, Neurokinin-1*/genetics , Vesicular Glutamate Transport Protein 2*/metabolism , Vesicular Glutamate Transport Protein 2*/genetics, Animals ; Mice ; Male ; Brain Stem/metabolism ; Brain Stem/drug effects ; Mice, Inbred C57BL ; RNA, Messenger/metabolism ; RNA, Messenger/genetics ; Respiratory Center/metabolism ; Respiratory Center/drug effects

المؤلفون: Zhu Z; Department of Pathology and Biomedical Science, University of Otago, Christchurch 8140, New Zealand., Chambers S; Department of Pathology and Biomedical Science, University of Otago, Christchurch 8140, New Zealand., Bhatia M; Department of Pathology and Biomedical Science, University of Otago, Christchurch 8140, New Zealand.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 13; Vol. 25 (12). Date of Electronic Publication: 2024 Jun 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Sepsis*/metabolism , Sepsis*/pathology , Substance P*/metabolism , Lung*/metabolism , Lung*/pathology , Liver*/metabolism , Liver*/pathology , Intercellular Adhesion Molecule-1*/metabolism , Intercellular Adhesion Molecule-1*/genetics , Endothelial Cells*/metabolism , Vascular Cell Adhesion Molecule-1*/metabolism , Vascular Cell Adhesion Molecule-1*/genetics , Receptors, Neurokinin-1*/metabolism , Receptors, Neurokinin-1*/genetics, Animals ; Mice ; Male ; Leukocytes/metabolism ; Mice, Inbred C57BL ; Peroxidase/metabolism ; Cell Adhesion Molecules/metabolism ; Cell Adhesion Molecules/genetics ; Disease Models, Animal

المؤلفون: Kriska T; Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States., Natarajan J; Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States., Herrnreiter A; Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States., Park SK; Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States., Pfister SL; Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States., Thomas MJ; Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States., Widiapradja A; Robert C. Byrd Health Sciences Center, Department of Physiology and Pharmacology, West Virginia University, Morgantown, Virginia, United States., Levick SP; Robert C. Byrd Health Sciences Center, Department of Physiology and Pharmacology, West Virginia University, Morgantown, Virginia, United States., Campbell WB; Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States.

المصدر: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2024 Jul 01; Vol. 327 (1), pp. C151-C167. Date of Electronic Publication: 2024 May 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1563 (Electronic) Linking ISSN: 03636143 NLM ISO Abbreviation: Am J Physiol Cell Physiol Subsets: MEDLINE

مواضيع طبية MeSH: Substance P*/metabolism , Receptors, Neurokinin-1*/metabolism , Receptors, Neurokinin-1*/agonists , Cyclic AMP*/metabolism , Signal Transduction*, Humans ; Animals ; HEK293 Cells ; Mice ; Fibroblasts/metabolism ; Fibroblasts/drug effects ; Calcium/metabolism

المؤلفون: Li M; Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China., Ma H; Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhang S; Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China., Peng Y; Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China., Ding L; State Key Laboratory for Chemistry and Molecular Engineering of Medical Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, China., Zhang Y; Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China., Min P; Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

المصدر: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2023 Jan 04; Vol. 13, pp. 1077514. Date of Electronic Publication: 2023 Jan 04 (Print Publication: 2022).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE

مواضيع طبية MeSH: Neurokinin-1 Receptor Antagonists*/pharmacology , Neurokinin-1 Receptor Antagonists*/therapeutic use , Diabetes Mellitus*/drug therapy , Diabetes Mellitus*/genetics, Humans ; Depression ; Aprepitant ; Antidepressive Agents/therapeutic use ; Receptors, Neurokinin-1/genetics ; Receptors, Neurokinin-1/metabolism