يعرض 1 - 10 نتائج من 1,334 نتيجة بحث عن '"nnrtis"', وقت الاستعلام: 0.81s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Design and optimization of piperidine-substituted thiophene[3,2-d]pyrimidine-based HIV-1 NNRTIs with improved drug resistance and pharmacokinetic profiles

    المؤلفون: Yanying Sun, Zhenzhen Zhou, Zhongling Shi, Fabao Zhao, Minghui Xie, Zongji Zhuo, Erik De Clercq, Christophe Pannecouque, Dongwei Kang, Peng Zhan, Xinyong Liu

    المصدر: Acta Pharmaceutica Sinica B, Vol 14, Iss 7, Pp 3110-3124 (2024)

    مصطلحات موضوعية: HIV-1, NNRTIs, NNIBP, Structural alert, Anti-HIV-1 drug candidate, Therapeutics. Pharmacology, RM1-950

    وصف الملف: electronic resource

    Relation: http://www.sciencedirect.com/science/article/pii/S2211383524001023; https://doaj.org/toc/2211-3835

    URL الوصول: https://doaj.org/article/11cdd506ac7a43449abb83e409f2a953

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  2. 2
    دورية أكاديمية
    Systematic approach to develop and validate High Performance Liquid Chromatographic method for efavirenz and its degradants

    المؤلفون: Sudhir Kumar Sahoo, Prasanta Kumar Choudhury, P N Murthy, Uma Shankar Mishra, Saroj Kanta Bisoyi, Lokesh Kumar

    المصدر: Journal of Applied Pharmaceutical Research, Vol 12, Iss 3, Pp 119-128 (2024)

    مصطلحات موضوعية: efavirenz, nnrtis, siams, purposeful degradation, ich guidelines, rp-hplc method, stress testing, Pharmacy and materia medica, RS1-441, Therapeutics. Pharmacology, RM1-950

    وصف الملف: electronic resource

    Relation: https://japtronline.com/index.php/joapr/article/view/586; https://doaj.org/toc/2348-0335

    URL الوصول: https://doaj.org/article/2b9149b1616c417ba0f06370a2623450

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  3. 3
    دورية أكاديمية
    In silico induction of missense mutation in NNRTI protein: computational modelling and stability study of modelled proteins

    المؤلفون: Sule, Laxmi, Gupta, Swagata, Jain, Nilanjana, Sapre, Nitin S.Aff4, IDs1091002301545w_cor4

    المصدر: Journal of Mathematical Chemistry. :1-22

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  4. 4
    دورية أكاديمية
    Structure-based design of novel heterocycle-substituted ATDP analogs as non-nucleoside reverse transcriptase inhibitors with improved selectivity and solubility

    المؤلفون: Li-Min Zhao, Christophe Pannecouque, Erik De Clercq, Shuai Wang, Fen-Er Chen

    المصدر: Acta Pharmaceutica Sinica B, Vol 13, Iss 12, Pp 4906-4917 (2023)

    مصطلحات موضوعية: HIV-1, RT, NNRTIs, ATDP, Pyridone, Therapeutics. Pharmacology, RM1-950

    وصف الملف: electronic resource

    Relation: http://www.sciencedirect.com/science/article/pii/S221138352300271X; https://doaj.org/toc/2211-3835

    URL الوصول: https://doaj.org/article/9fc6b09d87c44d3a900c1f299690c817

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  5. 5
    دورية أكاديمية
    A machine learning method for predicting the IC50 values of novel designed analogs of Non-Nucleoside Reverse-Transcriptase Inhibitors (NNRTIs) as potentially safer drugs

    المؤلفون: Mosos Néstor, Camargo-Roldan Tania, Montoya Ophir, Guevara-Pulido James

    المصدر: Informatics in Medicine Unlocked, Vol 48, Iss , Pp 101512- (2024)

    مصطلحات موضوعية: HIV, NNRTIs, CADD, Machine learning, And ANNs, Computer applications to medicine. Medical informatics, R858-859.7

    وصف الملف: electronic resource

    Relation: http://www.sciencedirect.com/science/article/pii/S2352914824000686; https://doaj.org/toc/2352-9148

    URL الوصول: https://doaj.org/article/6822581a196e4212af0c30481ad9828c

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  6. 6
    دورية أكاديمية
    Discovery of novel sulfonamide substituted indolylarylsulfones as potent HIV-1 inhibitors with better safety profiles

    المؤلفون: Shenghua Gao, Letian Song, Yusen Cheng, Fabao Zhao, Dongwei Kang, Shu Song, Mianling Yang, Bing Ye, Wei Zhao, Yajie Tang, Erik De Clercq, Christophe Pannecouque, Peng Zhan, Xinyong Liu

    المصدر: Acta Pharmaceutica Sinica B, Vol 13, Iss 6, Pp 2747-2764 (2023)

    مصطلحات موضوعية: HIV-1, NNRTIs, Indolylarylsulfone, Sulfonamide, Cytotoxicity, Therapeutics. Pharmacology, RM1-950

    وصف الملف: electronic resource

    Relation: http://www.sciencedirect.com/science/article/pii/S2211383523000035; https://doaj.org/toc/2211-3835

    URL الوصول: https://doaj.org/article/8964cae7904a4512954b69a8af82c05c

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  7. 7
    دورية أكاديمية
    HIV Infection, Antiretroviral Drugs, and the Vascular Endothelium

    المؤلفون: Georgette D. Kanmogne

    المصدر: Cells, Vol 13, Iss 8, p 672 (2024)

    مصطلحات موضوعية: HIV comorbidities, antiretrovirals, protease inhibitors, NRTIs, NNRTIs, INSTIs, Cytology, QH573-671

    وصف الملف: electronic resource

    Relation: https://www.mdpi.com/2073-4409/13/8/672; https://doaj.org/toc/2073-4409

    URL الوصول: https://doaj.org/article/5458c0e3ccb34ca987cd40283795bd09

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  8. 8
    دورية أكاديمية
    Bioinspired Pyrano[2,3-f]chromen-8-ones: Ring C-Opened Analogues of Calanolide A: Synthesis and Anti-HIV-1 Evaluation

    المؤلفون: Igor A. Khalymbadzha, Ramil F. Fatykhov, Ilya I. Butorin, Ainur D. Sharapov, Anastasia P. Potapova, Nibin Joy Muthipeedika, Grigory V. Zyryanov, Vsevolod V. Melekhin, Maria D. Tokhtueva, Sergey L. Deev, Marina K. Kukhanova, Nataliya N. Mochulskaya, Mikhail V. Tsurkan

    المصدر: Biomimetics, Vol 9, Iss 1, p 44 (2024)

    مصطلحات موضوعية: Calanolide A, anti-HIV activity, reverse transcriptase, non-nucleoside reverse transcriptase inhibitors (NNRTIs), Mannich reaction, CH/CH-coupling, Technology

    وصف الملف: electronic resource

    Relation: https://www.mdpi.com/2313-7673/9/1/44; https://doaj.org/toc/2313-7673

    URL الوصول: https://doaj.org/article/bb4f6881cd7241e0897dfbe5f9b17b6d

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  9. 9
    كتاب إلكتروني
    Principles of HIV Treatment

    المؤلفون: Pereira, Luis F.Aff4, Mgbako, Ofole U.Aff5, Paulino-Woolridge, JohannaAff6, Figueiredo, Miguel Edgar CardosoAff7, del Carmen, TessaAff8

    المساهمون: Bourgeois, James A., editorAff1, Cohen, Mary Ann Adler, editorAff2, Makurumidze, Getrude, editorAff3

    المصدر: HIV Psychiatry : A Practical Guide for Clinicians. :391-413

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  10. 10
    دورية أكاديمية
    The effects of ART on the dynamics of lipid profiles in Chinese Han HIV-infected patients: comparison between NRTI/NNRTI and NRTI/INSTI

    المؤلفون: Shengnan Liu, Baozhu Wei, Wei Liang, Tielong Chen, Liping Deng, Min Zhao, Jing Wan

    المصدر: Frontiers in Public Health, Vol 11 (2023)

    مصطلحات موضوعية: HIV, antiretroviral therapy, lipid profile, NNRTIs, INSTIs, generalized linear mixed-effects model, Public aspects of medicine, RA1-1270

    وصف الملف: electronic resource

    Relation: https://www.frontiersin.org/articles/10.3389/fpubh.2023.1161503/full; https://doaj.org/toc/2296-2565

    URL الوصول: https://doaj.org/article/da740192fd494bfc9de641ace0a49a15

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