المؤلفون: Kowal-Chwast A; Ryvu Therapeutics S.A., Leona Henryka Sternbacha 2, 30-394, Kraków, Poland. anna.kowal-chwast@ryvu.com.; Department of Analytical Chemistry and Biochemistry, Faculty of Materials Science and Ceramics, AGH University of Krakow, Al. Mickiewicza 30, 30-059, Kraków, Poland. anna.kowal-chwast@ryvu.com., Gabor-Worwa E; Ryvu Therapeutics S.A., Leona Henryka Sternbacha 2, 30-394, Kraków, Poland.; Department of Analytical Chemistry and Biochemistry, Faculty of Materials Science and Ceramics, AGH University of Krakow, Al. Mickiewicza 30, 30-059, Kraków, Poland., Gaud N; Ryvu Therapeutics S.A., Leona Henryka Sternbacha 2, 30-394, Kraków, Poland., Gogola D; Ryvu Therapeutics S.A., Leona Henryka Sternbacha 2, 30-394, Kraków, Poland., Piątek A; Ryvu Therapeutics S.A., Leona Henryka Sternbacha 2, 30-394, Kraków, Poland., Zarębski A; Ryvu Therapeutics S.A., Leona Henryka Sternbacha 2, 30-394, Kraków, Poland., Littlewood P; Ryvu Therapeutics S.A., Leona Henryka Sternbacha 2, 30-394, Kraków, Poland., Smoluch M; Department of Analytical Chemistry and Biochemistry, Faculty of Materials Science and Ceramics, AGH University of Krakow, Al. Mickiewicza 30, 30-059, Kraków, Poland., Brzózka K; Ryvu Therapeutics S.A., Leona Henryka Sternbacha 2, 30-394, Kraków, Poland., Kuś K; Ryvu Therapeutics S.A., Leona Henryka Sternbacha 2, 30-394, Kraków, Poland.

المصدر: Pharmacological reports : PR [Pharmacol Rep] 2024 Apr; Vol. 76 (2), pp. 400-415. Date of Electronic Publication: 2024 Mar 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101234999 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2299-5684 (Electronic) Linking ISSN: 17341140 NLM ISO Abbreviation: Pharmacol Rep Subsets: MEDLINE

مواضيع طبية MeSH: Dextrans* , Organic Anion Transporters*/genetics , Organic Anion Transporters*/metabolism, Humans ; Solute Carrier Organic Anion Transporter Family Member 1B3/genetics ; Solute Carrier Organic Anion Transporter Family Member 1B3/metabolism ; Solute Carrier Organic Anion Transporter Family Member 1B3/pharmacology ; Liver-Specific Organic Anion Transporter 1/genetics ; Liver-Specific Organic Anion Transporter 1/metabolism ; Liver-Specific Organic Anion Transporter 1/pharmacology ; HEK293 Cells ; Hepatocytes/metabolism ; Liver ; Membrane Transport Proteins/metabolism ; Albumins ; Organic Anion Transporters, Sodium-Independent/genetics ; Organic Anion Transporters, Sodium-Independent/metabolism

المؤلفون: Wang FH; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD study, Beijing Key Laboratory of Active Substances Discovery and Drug Ability Evaluation, Department of Drug Metabolism, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China., Tan HX; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD study, Beijing Key Laboratory of Active Substances Discovery and Drug Ability Evaluation, Department of Drug Metabolism, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China., Hu JH; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD study, Beijing Key Laboratory of Active Substances Discovery and Drug Ability Evaluation, Department of Drug Metabolism, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.; Department of Health Management and Service, Cangzhou Medical College, Cangzhou 061001, China., Duan XY; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD study, Beijing Key Laboratory of Active Substances Discovery and Drug Ability Evaluation, Department of Drug Metabolism, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China., Bai WT; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD study, Beijing Key Laboratory of Active Substances Discovery and Drug Ability Evaluation, Department of Drug Metabolism, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China., Wang XB; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD study, Beijing Key Laboratory of Active Substances Discovery and Drug Ability Evaluation, Department of Drug Metabolism, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China., Wang BL; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD study, Beijing Key Laboratory of Active Substances Discovery and Drug Ability Evaluation, Department of Drug Metabolism, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China., Su Y; Department of Health Management and Service, Cangzhou Medical College, Cangzhou 061001, China., Hu JP; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD study, Beijing Key Laboratory of Active Substances Discovery and Drug Ability Evaluation, Department of Drug Metabolism, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.

المصدر: Journal of Asian natural products research [J Asian Nat Prod Res] 2024 Mar; Vol. 26 (3), pp. 353-371. Date of Electronic Publication: 2023 Aug 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 100888334 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-2213 (Electronic) Linking ISSN: 10286020 NLM ISO Abbreviation: J Asian Nat Prod Res Subsets: MEDLINE

مواضيع طبية MeSH: Acute Kidney Injury*/drug therapy , Acute Kidney Injury*/metabolism , Flavonoids*/pharmacology , Flavonoids*/chemistry , Organic Anion Transporters, Sodium-Independent*/drug effects , Organic Anion Transporters, Sodium-Independent*/metabolism, Biological Transport ; Organic Anion Transporters/drug effects ; Organic Anion Transporters/metabolism ; Structure-Activity Relationship

المؤلفون: Thakur A; College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, WA 99202, USA., Saradhi Mettu V; College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, WA 99202, USA., Singh DK; College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, WA 99202, USA., Prasad B; College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, WA 99202, USA. Electronic address: bhagwat.prasad@wsu.edu.

المصدر: Biochemical pharmacology [Biochem Pharmacol] 2023 Dec; Vol. 218, pp. 115867. Date of Electronic Publication: 2023 Oct 20.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Organic Anion Transporters*/metabolism, Rats ; Animals ; Probenecid/pharmacology ; Probenecid/metabolism ; Organic Anion Transporters, Sodium-Independent/metabolism ; Renal Elimination ; Furosemide/pharmacology ; Furosemide/metabolism ; Organic Anion Transport Protein 1/metabolism ; Kynurenic Acid/metabolism ; Kynurenic Acid/pharmacology ; Pyridoxic Acid/metabolism ; Pyridoxic Acid/pharmacology ; Drug Interactions ; Biomarkers/metabolism ; Kidney/metabolism

المؤلفون: Ungvári O; Institute of Enzymology, RCNS, Eötvös Loránd Research Network, Budapest, Hungary.; Doctoral School of Biology, Institute of Biology, Eötvös Loránd University, Budapest, Hungary., Bakos É; Institute of Enzymology, RCNS, Eötvös Loránd Research Network, Budapest, Hungary., Kovacsics D; Institute of Enzymology, RCNS, Eötvös Loránd Research Network, Budapest, Hungary., Özvegy-Laczka C; Institute of Enzymology, RCNS, Eötvös Loránd Research Network, Budapest, Hungary.

المصدر: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2023 Nov; Vol. 37 (11), pp. e23223.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

مواضيع طبية MeSH: Organic Anion Transporters*/metabolism, Organic Anion Transporters, Sodium-Independent/metabolism ; Pentamidine ; Liver-Specific Organic Anion Transporter 1/metabolism ; Fluorescence ; Biological Transport ; Peptides

المؤلفون: Lash LH; Department of Pharmacology, Wayne State University School of Medicine, Detroit, Michigan l.h.lash@wayne.edu.

المصدر: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2023 Nov; Vol. 387 (2), pp. 131-134.

نوع المنشور: Journal Article; Comment

بيانات الدورية: Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0376362 Publication Model: Print Cited Medium: Internet ISSN: 1521-0103 (Electronic) Linking ISSN: 00223565 NLM ISO Abbreviation: J Pharmacol Exp Ther Subsets: MEDLINE

مواضيع طبية MeSH: Organic Anion Transporters*/metabolism , Biliary Tract*/metabolism, Humans ; Liver/metabolism ; Hepatocytes/metabolism ; Biological Transport ; Organic Anion Transporters, Sodium-Independent/metabolism ; Solute Carrier Organic Anion Transporter Family Member 1B3 ; Drug Interactions

المؤلفون: Asensio M; Experimental Hepatology and Drug Targeting (HEVEPHARM), University of Salamanca, Salamanca, Spain; Institute for Biomedical Research of Salamanca (IBSAL), Salamanca, Spain; Centro de Investigación Biomédica en Red de enfermedades Hepáticas y Digestivas (CIBEREHD), Carlos III National Institute of Health, Madrid, Spain., Herraez E; Experimental Hepatology and Drug Targeting (HEVEPHARM), University of Salamanca, Salamanca, Spain; Institute for Biomedical Research of Salamanca (IBSAL), Salamanca, Spain; Centro de Investigación Biomédica en Red de enfermedades Hepáticas y Digestivas (CIBEREHD), Carlos III National Institute of Health, Madrid, Spain., Macias RIR; Experimental Hepatology and Drug Targeting (HEVEPHARM), University of Salamanca, Salamanca, Spain; Institute for Biomedical Research of Salamanca (IBSAL), Salamanca, Spain; Centro de Investigación Biomédica en Red de enfermedades Hepáticas y Digestivas (CIBEREHD), Carlos III National Institute of Health, Madrid, Spain., Lozano E; Experimental Hepatology and Drug Targeting (HEVEPHARM), University of Salamanca, Salamanca, Spain; Institute for Biomedical Research of Salamanca (IBSAL), Salamanca, Spain; Centro de Investigación Biomédica en Red de enfermedades Hepáticas y Digestivas (CIBEREHD), Carlos III National Institute of Health, Madrid, Spain., Muñoz-Bellvís L; Institute for Biomedical Research of Salamanca (IBSAL), Salamanca, Spain; Service of General and Gastrointestinal Surgery, University Hospital of Salamanca, Salamanca, Spain; Centro de Investigación Biomédica en Red del Cáncer (CIBERONC), Carlos III National Institute of Health, Madrid, Spain., Sanchez-Vicente L; Experimental Hepatology and Drug Targeting (HEVEPHARM), University of Salamanca, Salamanca, Spain., Morente-Carrasco A; Experimental Hepatology and Drug Targeting (HEVEPHARM), University of Salamanca, Salamanca, Spain; Area of Physiology, Faculty of Health Sciences, University Rey Juan Carlos, Alcorcón, Madrid, Spain., Marin JJG; Experimental Hepatology and Drug Targeting (HEVEPHARM), University of Salamanca, Salamanca, Spain; Institute for Biomedical Research of Salamanca (IBSAL), Salamanca, Spain; Centro de Investigación Biomédica en Red de enfermedades Hepáticas y Digestivas (CIBEREHD), Carlos III National Institute of Health, Madrid, Spain. Electronic address: jjgmarin@usal.es., Briz O; Experimental Hepatology and Drug Targeting (HEVEPHARM), University of Salamanca, Salamanca, Spain; Institute for Biomedical Research of Salamanca (IBSAL), Salamanca, Spain; Centro de Investigación Biomédica en Red de enfermedades Hepáticas y Digestivas (CIBEREHD), Carlos III National Institute of Health, Madrid, Spain.

المصدر: Biochemical pharmacology [Biochem Pharmacol] 2023 Aug; Vol. 214, pp. 115681. Date of Electronic Publication: 2023 Jul 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/therapeutic use , Carcinoma, Hepatocellular*/drug therapy , Carcinoma, Hepatocellular*/metabolism , Liver Neoplasms*/drug therapy , Liver Neoplasms*/metabolism , Organic Anion Transporters*/metabolism, Animals ; Mice ; Cisplatin/metabolism ; Organic Anion Transporters, Sodium-Independent/metabolism ; Solute Carrier Organic Anion Transporter Family Member 1B3/genetics ; Humans

المؤلفون: Bi Y; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, P. R. China., Xing Y; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, P. R. China.; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, P. R. China., Gui C; College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, P. R. China., Tian Y; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, P. R. China., Zhang M; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, P. R. China., Yao Y; School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, P. R. China., Hu G; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, P. R. China., Han L; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, P. R. China., He F; School of Pharmaceutical Sciences, Guizhou Medical University, Guiyang, Guizhou, P. R. China., Zhang Y; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, P. R. China.

المصدر: Planta medica [Planta Med] 2023 Aug; Vol. 89 (10), pp. 940-951. Date of Electronic Publication: 2023 May 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: George Thieme Country of Publication: Germany NLM ID: 0066751 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-0221 (Electronic) Linking ISSN: 00320943 NLM ISO Abbreviation: Planta Med Subsets: MEDLINE

مواضيع طبية MeSH: Organic Anion Transporters*, Rats ; Animals ; Organic Anion Transporters, Sodium-Independent ; Liver-Specific Organic Anion Transporter 1 ; Solute Carrier Organic Anion Transporter Family Member 1B3 ; Chlorogenic Acid ; Medicine, Chinese Traditional ; Drug Interactions ; Peptides ; Nonprescription Drugs

المؤلفون: Orozco CC; Pharmacokinetics, Dynamics, and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Neuvonen M; Department of Clinical Pharmacology, University of Helsinki, Helsinki FI-00014, Finland.; Individualized Drug Therapy Research Program, University of Helsinki, Helsinki FI-00014, Finland., Bi YA; Pharmacokinetics, Dynamics, and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Cerny MA; Pharmacokinetics, Dynamics, and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Mathialagan S; Pharmacokinetics, Dynamics, and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Tylaska L; Pharmacokinetics, Dynamics, and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Rago B; Pharmacokinetics, Dynamics, and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Costales C; Pharmacokinetics, Dynamics, and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., King-Ahmad A; Pharmacokinetics, Dynamics, and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States., Niemi M; Department of Clinical Pharmacology, University of Helsinki, Helsinki FI-00014, Finland.; Individualized Drug Therapy Research Program, University of Helsinki, Helsinki FI-00014, Finland.; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki FI-00029, Finland., Rodrigues AD; Pharmacokinetics, Dynamics, and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States.

المصدر: Molecular pharmaceutics [Mol Pharm] 2023 Jun 05; Vol. 20 (6), pp. 3020-3032. Date of Electronic Publication: 2023 May 03.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-8392 (Electronic) Linking ISSN: 15438384 NLM ISO Abbreviation: Mol Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Organic Anion Transporters*/genetics , Organic Anion Transporters*/metabolism, Humans ; Sulfates ; Solute Carrier Organic Anion Transporter Family Member 1B3/metabolism ; Liver-Specific Organic Anion Transporter 1/genetics ; Liver-Specific Organic Anion Transporter 1/metabolism ; Bile Acids and Salts ; Biological Transport/physiology ; Biomarkers/metabolism ; Organic Anion Transporters, Sodium-Independent/metabolism

المؤلفون: Cheng YY; School of Medicine, National Taiwan University College of Medicine, Taipei, Taiwan., Chang KC; Department of Pediatrics, National Taiwan University Children's Hospital, National Taiwan University College of Medicine, Taipei, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan., Chen PL; Graduate Institute of Medical Genomics and Proteomics, National Taiwan University College of Medicine, Taiwan; Department of Medical Genetics, National Taiwan University Hospital, Taipei, Taiwan; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan., Yeung CY; Department of Pediatric Gastroenterology, Hepatology and Nutrition, MacKay Children's Hospital, Taipei, Taiwan., Liou BY; Department of Pediatrics, National Taiwan University Children's Hospital, National Taiwan University College of Medicine, Taipei, Taiwan., Chen HL; Department of Pediatrics, National Taiwan University Children's Hospital, National Taiwan University College of Medicine, Taipei, Taiwan; Department of Medical Education and Bioethics, National Taiwan, University College of Medicine, Taipei, Taiwan; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan. Electronic address: hueyling@ntu.edu.tw.

المصدر: Journal of the Formosan Medical Association = Taiwan yi zhi [J Formos Med Assoc] 2023 Jul; Vol. 122 (7), pp. 648-652. Date of Electronic Publication: 2023 Mar 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Formosan Medical Association, Elsevier Country of Publication: Singapore NLM ID: 9214933 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0929-6646 (Print) Linking ISSN: 09296646 NLM ISO Abbreviation: J Formos Med Assoc Subsets: MEDLINE

مواضيع طبية MeSH: Organic Anion Transporters*/genetics , Hyperbilirubinemia, Hereditary*/genetics, Adult ; Infant, Newborn ; Humans ; Child ; Organic Anion Transporters, Sodium-Independent/genetics ; Liver-Specific Organic Anion Transporter 1/genetics ; Solute Carrier Organic Anion Transporter Family Member 1B3/genetics ; Hyperbilirubinemia ; Mutation

المؤلفون: Liu R; Drug Metabolism, Gilead Sciences Inc., Foster City, California., Hao J; Drug Metabolism, Gilead Sciences Inc., Foster City, California., Zhao X; Drug Metabolism, Gilead Sciences Inc., Foster City, California., Lai Y; Drug Metabolism, Gilead Sciences Inc., Foster City, California yurong.lai@gilead.com.

المصدر: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2023 Jul; Vol. 51 (7), pp. 844-850. Date of Electronic Publication: 2023 Apr 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: United States NLM ID: 9421550 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-009X (Electronic) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab Dispos Subsets: MEDLINE

مواضيع طبية MeSH: Probenecid*/pharmacology , Probenecid*/metabolism , Organic Anion Transporters*/metabolism, Humans ; Animals ; Macaca fascicularis/metabolism ; Pyridoxic Acid ; Homovanillic Acid ; Feasibility Studies ; Kynurenic Acid ; Biomarkers/metabolism ; Drug Interactions ; Kidney/metabolism ; Organic Anion Transporters, Sodium-Independent/metabolism ; Organic Anion Transport Protein 1/metabolism