المؤلفون: Ma Y; The First Clinical Medical School, Lanzhou University, Lanzhou, China., Wang X; The First Clinical Medical School, Lanzhou University, Lanzhou, China., Gou X; School of Pharmacy, Lanzhou University, Lanzhou, China., Wu X; The First Clinical Medical School, Lanzhou University, Lanzhou, China.; School of Pharmacy, Lanzhou University, Lanzhou, China.

المصدر: Biopharmaceutics & drug disposition [Biopharm Drug Dispos] 2024 Feb; Vol. 45 (1), pp. 43-57. Date of Electronic Publication: 2024 Feb 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 7911226 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-081X (Electronic) Linking ISSN: 01422782 NLM ISO Abbreviation: Biopharm Drug Dispos Subsets: MEDLINE

مواضيع طبية MeSH: Organic Cation Transporter 1*/metabolism , Organic Cation Transport Proteins*/genetics , Organic Cation Transport Proteins*/metabolism, Humans ; Histamine/metabolism ; Serotonin/metabolism ; Kidney/metabolism ; Thiamine/metabolism ; HEK293 Cells

المؤلفون: Gebauer L; Institute of Clinical Pharmacology, University Medical Center Göttingen, Göttingen D-37075, Germany., Jensen O; Institute of Clinical Pharmacology, University Medical Center Göttingen, Göttingen D-37075, Germany., Rafehi M; Institute of Clinical Pharmacology, University Medical Center Göttingen, Göttingen D-37075, Germany., Brockmöller J; Institute of Clinical Pharmacology, University Medical Center Göttingen, Göttingen D-37075, Germany.

المصدر: Journal of medicinal chemistry [J Med Chem] 2023 Dec 14; Vol. 66 (23), pp. 15990-16001. Date of Electronic Publication: 2023 Dec 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Organic Cation Transporter 1*/metabolism , Organic Cation Transport Proteins*, Biological Transport ; Protein Binding ; Cations ; Organic Cation Transporter 2/metabolism

المؤلفون: Gebauer L; Institute of Clinical Pharmacology, University Medical Center Göttingen, D-37075 Göttingen, Germany., Jensen O; Institute of Clinical Pharmacology, University Medical Center Göttingen, D-37075 Göttingen, Germany., Rafehi M; Institute of Clinical Pharmacology, University Medical Center Göttingen, D-37075 Göttingen, Germany., Brockmöller J; Institute of Clinical Pharmacology, University Medical Center Göttingen, D-37075 Göttingen, Germany.

المصدر: Molecular pharmaceutics [Mol Pharm] 2023 Dec 04; Vol. 20 (12), pp. 6289-6300. Date of Electronic Publication: 2023 Nov 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-8392 (Electronic) Linking ISSN: 15438384 NLM ISO Abbreviation: Mol Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Organic Cation Transporter 1*/metabolism , Membrane Transport Proteins*, Biological Transport ; Drug Interactions ; Cations ; Organic Cation Transport Proteins/metabolism ; Organic Cation Transporter 2/metabolism

المؤلفون: An H; Zhejiang Key Laboratory of Neuropsychiatric Drug Research, School of Pharmacy, Hangzhou Medical College, Hangzhou, Zhejiang, China., Fang J; Zhejiang Key Laboratory of Neuropsychiatric Drug Research, School of Pharmacy, Hangzhou Medical College, Hangzhou, Zhejiang, China., Wang M; Zhejiang Key Laboratory of Neuropsychiatric Drug Research, School of Pharmacy, Hangzhou Medical College, Hangzhou, Zhejiang, China., Lin H; Zhejiang Key Laboratory of Neuropsychiatric Drug Research, School of Pharmacy, Hangzhou Medical College, Hangzhou, Zhejiang, China., Sun Y; Zhejiang Key Laboratory of Neuropsychiatric Drug Research, School of Pharmacy, Hangzhou Medical College, Hangzhou, Zhejiang, China., Hu B; Zhejiang Key Laboratory of Neuropsychiatric Drug Research, School of Pharmacy, Hangzhou Medical College, Hangzhou, Zhejiang, China., He Z; Zhejiang Key Laboratory of Neuropsychiatric Drug Research, School of Pharmacy, Hangzhou Medical College, Hangzhou, Zhejiang, China., Ge Z; Zhejiang Key Laboratory of Neuropsychiatric Drug Research, School of Pharmacy, Hangzhou Medical College, Hangzhou, Zhejiang, China., Wei Y; Zhejiang Key Laboratory of Neuropsychiatric Drug Research, School of Pharmacy, Hangzhou Medical College, Hangzhou, Zhejiang, China.

المصدر: Chirality [Chirality] 2023 Dec; Vol. 35 (12), pp. 983-992. Date of Electronic Publication: 2023 Jul 18.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 8914261 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-636X (Electronic) Linking ISSN: 08990042 NLM ISO Abbreviation: Chirality Subsets: MEDLINE

مواضيع طبية MeSH: Fluoxetine*/analysis , Fluoxetine*/metabolism , Organic Cation Transporter 1*/metabolism, Rats ; Animals ; Blood-Brain Barrier ; Chromatography, Liquid/methods ; Stereoisomerism ; Tandem Mass Spectrometry/methods

المؤلفون: Zeng YC; Molecular, Structural and Computational Biology Division, The Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia. y.zeng@victorchang.edu.au.; School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, NSW, Australia. y.zeng@victorchang.edu.au., Sobti M; Molecular, Structural and Computational Biology Division, The Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia.; School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, NSW, Australia., Quinn A; Australian Institute of Bioengineering and Nanotechnology, University of Queensland, Brisbane, QLD, Australia., Smith NJ; School of Biomedical Sciences, Faculty of Medicine & Health, UNSW Sydney, Kensington, NSW, Australia., Brown SHJ; School of Chemistry and Molecular Bioscience, Molecular Horizons, and Australian Research Council Centre for Cryo-electron Microscopy of Membrane Proteins, University of Wollongong, Wollongong, NSW, Australia., Vandenberg JI; School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, NSW, Australia.; Molecular Cardiology and Biophysics Division, The Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia., Ryan RM; School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia., O'Mara ML; Australian Institute of Bioengineering and Nanotechnology, University of Queensland, Brisbane, QLD, Australia., Stewart AG; Molecular, Structural and Computational Biology Division, The Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia. a.stewart@victorchang.edu.au.; School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, NSW, Australia. a.stewart@victorchang.edu.au.

المصدر: Nature communications [Nat Commun] 2023 Oct 11; Vol. 14 (1), pp. 6374. Date of Electronic Publication: 2023 Oct 11.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Organic Cation Transporter 1*/genetics , Organic Cation Transporter 1*/chemistry , Organic Cation Transporter 1*/metabolism , Organic Cation Transport Proteins*/chemistry, Humans ; Biological Transport ; Organic Cation Transporter 2/metabolism

المؤلفون: Malani M; Translational Pharmaceutics Research Laboratory, Birla Institute of Technology and Science-Pilani, Hyderabad, Telangana, India., Hiremath MS; Translational Pharmaceutics Research Laboratory, Birla Institute of Technology and Science-Pilani, Hyderabad, Telangana, India., Sharma S; Department of Computer Science and Information Systems (CSIS), Birla Institute of Technology & Science-Pilani, Hyderabad, Telangana, India., Jhunjhunwala M; Department of Computer Science and Information Systems (CSIS), Birla Institute of Technology & Science-Pilani, Hyderabad, Telangana, India., Gayen S; Laboratory of Drug Design and Discovery, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, West Bengal, India., Hota C; Department of Computer Science and Information Systems (CSIS), Birla Institute of Technology & Science-Pilani, Hyderabad, Telangana, India., Nirmal J; Translational Pharmaceutics Research Laboratory, Birla Institute of Technology and Science-Pilani, Hyderabad, Telangana, India.

المصدر: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2024 Jul; Vol. 42 (10), pp. 5207-5218. Date of Electronic Publication: 2023 Jun 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE

مواضيع طبية MeSH: Molecular Dynamics Simulation* , Artificial Intelligence*, Humans ; Molecular Docking Simulation ; Ligands ; Organic Cation Transport Proteins/chemistry ; Organic Cation Transport Proteins/metabolism ; Protein Binding ; Machine Learning ; Binding Sites ; Organic Cation Transporter 1/chemistry ; Organic Cation Transporter 1/metabolism

المؤلفون: Yee SW; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94143, USA., Macdonald CB; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94143, USA., Mitrovic D; Science for Life Laboratory, Department of Applied Physics, KTH Royal Institute of Technology, 12121 Solna, Stockholm, Stockholm County 114 28, Sweden., Zhou X; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94143, USA., Koleske ML; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94143, USA., Yang J; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94143, USA., Buitrago Silva D; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94143, USA., Rockefeller Grimes P; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94143, USA., Trinidad DD; Department of Medicine, Division of Infectious Disease, University of California, San Francisco, San Francisco, CA 94143, USA., More SS; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94143, USA., Kachuri L; Department of Epidemiology and Population Health, Stanford University, Stanford, CA 94305, USA; Stanford Cancer Institute, Stanford University, Stanford, CA 94305, USA., Witte JS; Department of Epidemiology and Population Health, Stanford University, Stanford, CA 94305, USA; Stanford Cancer Institute, Stanford University, Stanford, CA 94305, USA., Delemotte L; Science for Life Laboratory, Department of Applied Physics, KTH Royal Institute of Technology, 12121 Solna, Stockholm, Stockholm County 114 28, Sweden. Electronic address: lucie.delemotte@scilifelab.se., Giacomini KM; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: kathy.giacomini@ucsf.edu., Coyote-Maestas W; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94143, USA; Quantitative Biosciences Institute, University of California, San Francisco, San Francisco, CA 94143, USA; Chan Zuckerberg Biohub, San Francisco, CA 94148, USA. Electronic address: willow.coyote-maestas@ucsf.edu.

المصدر: Molecular cell [Mol Cell] 2024 May 16; Vol. 84 (10), pp. 1932-1947.e10. Date of Electronic Publication: 2024 May 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

مواضيع طبية MeSH: Molecular Dynamics Simulation*, Humans ; HEK293 Cells ; Structure-Activity Relationship ; Mutation, Missense ; Pharmacogenetics ; Phenotype ; Organic Cation Transporter 1/genetics ; Organic Cation Transporter 1/metabolism ; Mutation ; Protein Conformation ; Biological Transport ; Octamer Transcription Factor-1

المؤلفون: Gebauer L; Institute of Clinical Pharmacology, University Medical Center Göttingen, D-37075 Göttingen, Germany. Electronic address: lukas.gebauer@med.uni-goettingen.de., Dücker C; Institute of Clinical Pharmacology, University Medical Center Göttingen, D-37075 Göttingen, Germany., Jensen O; Institute of Clinical Pharmacology, University Medical Center Göttingen, D-37075 Göttingen, Germany., Brockmöller J; Institute of Clinical Pharmacology, University Medical Center Göttingen, D-37075 Göttingen, Germany.

المصدر: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2023 May; Vol. 161, pp. 114454. Date of Electronic Publication: 2023 Mar 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE

مواضيع طبية MeSH: Cytochrome P-450 CYP2D6*/metabolism , Organic Cation Transporter 1*/genetics , Organic Cation Transporter 1*/metabolism

المؤلفون: Redeker KM; Institute of Clinical Pharmacology, University Medical Center Göttingen, D-37075 Göttingen, Germany. Electronic address: kyra-elisamaria.redeker@med.uni-goettingen.de., Schröder S; Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), D-37075 Göttingen, Germany., Dücker C; Institute of Clinical Pharmacology, University Medical Center Göttingen, D-37075 Göttingen, Germany., Brockmöller J; Institute of Clinical Pharmacology, University Medical Center Göttingen, D-37075 Göttingen, Germany., Gebauer L; Institute of Clinical Pharmacology, University Medical Center Göttingen, D-37075 Göttingen, Germany.

المصدر: Biochemical pharmacology [Biochem Pharmacol] 2024 May; Vol. 223, pp. 116188. Date of Electronic Publication: 2024 Apr 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Amino Acids* , Organic Cation Transport Proteins*/genetics , Organic Cation Transport Proteins*/metabolism, Humans ; Cations/metabolism ; Mutagenesis ; Organic Cation Transporter 1/metabolism ; Organic Cation Transporter 2

المؤلفون: Singh S; Molecular and Human Genetics Laboratory, Department of Zoology, University of Lucknow., Shukla AK; Molecular and Human Genetics Laboratory, Department of Zoology, University of Lucknow., Usman K; Department of Medicine, King George's Medical University Lucknow, India., Banerjee M; Molecular and Human Genetics Laboratory, Department of Zoology, University of Lucknow.

المصدر: Pharmacogenetics and genomics [Pharmacogenet Genomics] 2023 Apr 01; Vol. 33 (3), pp. 51-58. Date of Electronic Publication: 2023 Feb 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101231005 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-6880 (Electronic) Linking ISSN: 17446872 NLM ISO Abbreviation: Pharmacogenet Genomics Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes Mellitus, Type 2*/drug therapy , Diabetes Mellitus, Type 2*/genetics , Metformin*/therapeutic use , Organic Cation Transporter 1*/genetics, Humans ; Alleles ; Genotype ; Pharmacogenetics