المؤلفون: Rizk FH; Department of Physiology, Faculty of Medicine, Tanta University, Tanta, Egypt., El Saadany AA; Department of Pharmacology, Faculty of Medicine, Tanta University, Tanta, Egypt., Elshamy AM; Department of Medical Biochemistry, Faculty of Medicine, Tanta University, Tanta, Egypt., Abd Ellatif RA; Department of Anatomy and Embryology, Faculty of Medicine, Tanta University, Tanta, Egypt., El-Guindy DM; Department of Pathology, Faculty of Medicine, Tanta University, Tanta, Egypt., Helal DS; Department of Pathology, Faculty of Medicine, Tanta University, Tanta, Egypt., Hamama MG; Department of Anatomy and Embryology, Faculty of Medicine, Tanta University, Tanta, Egypt., El-Sharnoby JAE; Department of Clinical Pathology, Faculty of Medicine, Tanta University, Tanta, Egypt., Abdel Ghafar MT; Department of Clinical Pathology, Faculty of Medicine, Tanta University, Tanta, Egypt., Faheem H; Department of Physiology, Faculty of Medicine, Tanta University, Tanta, Egypt.

المصدر: The Journal of physiology [J Physiol] 2024 Aug; Vol. 602 (15), pp. 3621-3639. Date of Electronic Publication: 2024 Jul 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cambridge Univ. Press Country of Publication: England NLM ID: 0266262 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-7793 (Electronic) Linking ISSN: 00223751 NLM ISO Abbreviation: J Physiol Subsets: MEDLINE

مواضيع طبية MeSH: Polycystic Ovary Syndrome*/drug therapy , Polycystic Ovary Syndrome*/chemically induced , Polycystic Ovary Syndrome*/metabolism , Letrozole*/pharmacology , Gastrointestinal Microbiome*/drug effects, Animals ; Female ; Rats ; Rats, Sprague-Dawley ; Inflammation/drug therapy ; Inflammation/metabolism ; Ovary/drug effects ; Ovary/metabolism ; Peptides/pharmacology ; Insulin Resistance ; Blood Proteins

المؤلفون: Guan HR; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, PR China., Li B; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, PR China; Zhejiang Provincial Key Laboratory of TCM for Innovative R & D and Digital Intelligent Manufacturing of TCM Great Health Products. Huzhou, Zhejiang Province, 313000, PR China., Zhang ZH; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, PR China., Wu HS; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, PR China., Wang N; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, PR China., Chen XF; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, PR China., Zhou CL; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, PR China., Bian XR; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, PR China., Li L; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, PR China., Xu WF; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, PR China., He XL; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, PR China., Dong YJ; College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, PR China., Jiang NH; The Second Affiliated Hospital of Jiaxing University, Jiaxing, 314000, PR China. Electronic address: jiangninghua@zjxu.edu.cn., Su J; College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, PR China. Electronic address: sujie198169@126.com., Lv GY; College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, PR China. Electronic address: zjtcmlgy@163.com., Chen SH; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, PR China; Zhejiang Provincial Key Laboratory of TCM for Innovative R & D and Digital Intelligent Manufacturing of TCM Great Health Products. Huzhou, Zhejiang Province, 313000, PR China. Electronic address: chensuhong@zjut.edu.cn.

المصدر: Journal of ethnopharmacology [J Ethnopharmacol] 2024 Sep 15; Vol. 331, pp. 118274. Date of Electronic Publication: 2024 Apr 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Polycystic Ovary Syndrome*/drug therapy , Polycystic Ovary Syndrome*/chemically induced , Toll-Like Receptor 4*/metabolism , Lipopolysaccharides* , Signal Transduction*/drug effects , Drugs, Chinese Herbal*/pharmacology, Animals ; Female ; Mice ; Insulin Resistance ; Diet, High-Fat/adverse effects ; Disease Models, Animal ; Dehydroepiandrosterone/pharmacology ; Capsules ; Intestines/drug effects ; Mice, Inbred C57BL ; Ovary/drug effects ; Ovary/metabolism ; Ovary/pathology

المؤلفون: Magdy N; Quality Assurance, National Food Safety Authority, Bab El-Louq, Cairo, Egypt., Abdelkader NF; Pharmacology and Toxicology Department, Faculty of Pharmacy, Cairo University, Egypt., Zaki HF; Pharmacology and Toxicology Department, Faculty of Pharmacy, Cairo University, Egypt., Kamel AS; Pharmacology and Toxicology Department, Faculty of Pharmacy, Cairo University, Egypt. Electronic address: ahmed.seifeldin@pharma.cu.edu.eg.

المصدر: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2024 Sep; Vol. 191, pp. 114874. Date of Electronic Publication: 2024 Jul 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8207483 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6351 (Electronic) Linking ISSN: 02786915 NLM ISO Abbreviation: Food Chem Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Polycystic Ovary Syndrome*/chemically induced , Polycystic Ovary Syndrome*/metabolism , Letrozole* , Saccharin*/administration & dosage , Disease Models, Animal*, Animals ; Female ; Rats ; Receptors, G-Protein-Coupled/metabolism ; Apoptosis/drug effects ; Rats, Sprague-Dawley ; Sweetening Agents/toxicity ; Ovary/drug effects ; Ovary/metabolism

المؤلفون: Li J; Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen 518033, Guangdong, China., Liu D; Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen 518033, Guangdong, China; Guangzhou University of Chinese Medicine, Guangzhou 510405, China., Zhao H; Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen 518033, Guangdong, China; Guangzhou University of Chinese Medicine, Guangzhou 510405, China., Zhang P; Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen 518033, Guangdong, China; Guangzhou University of Chinese Medicine, Guangzhou 510405, China., Cai F; Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen 518033, Guangdong, China; Guangzhou University of Chinese Medicine, Guangzhou 510405, China., Li H; Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen 518033, Guangdong, China; Guangzhou University of Chinese Medicine, Guangzhou 510405, China. Electronic address: sztcmlhl@163.com., Chu S; Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen 518033, Guangdong, China; Guangzhou University of Chinese Medicine, Guangzhou 510405, China. Electronic address: chushufanggzhtcm@163.com.

المصدر: International immunopharmacology [Int Immunopharmacol] 2024 Aug 20; Vol. 137, pp. 112491. Date of Electronic Publication: 2024 Jun 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Polycystic Ovary Syndrome*/drug therapy , Polycystic Ovary Syndrome*/chemically induced , Polycystic Ovary Syndrome*/immunology , Gastrointestinal Microbiome*/drug effects , Drugs, Chinese Herbal*/pharmacology , Drugs, Chinese Herbal*/therapeutic use , Disease Models, Animal* , Dehydroepiandrosterone* , Anti-Inflammatory Agents*/pharmacology , Anti-Inflammatory Agents*/therapeutic use, Animals ; Female ; Mice ; Ovary/pathology ; Ovary/drug effects ; Ovary/immunology ; Ovary/metabolism ; Humans ; Macrophages/drug effects ; Macrophages/immunology ; RAW 264.7 Cells ; Cytokines/metabolism ; Apoptosis/drug effects ; NF-kappa B/metabolism ; Diet, High-Fat/adverse effects ; Inflammation/drug therapy ; Mice, Inbred C57BL

المؤلفون: Lee YZ; Biomedical Industry Ph.D. Program, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan., Cheng SH; Bened Biomedical Co., Ltd., Taipei 115011, Taiwan., Lin YF; Bened Biomedical Co., Ltd., Taipei 115011, Taiwan., Wu CC; Bened Biomedical Co., Ltd., Taipei 115011, Taiwan., Tsai YC; Biomedical Industry Ph.D. Program, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.; Institute of Biochemistry and Molecular Biology, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 09; Vol. 25 (16). Date of Electronic Publication: 2024 Aug 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Polycystic Ovary Syndrome*/chemically induced , Polycystic Ovary Syndrome*/drug therapy , Polycystic Ovary Syndrome*/metabolism , Letrozole* , Disease Models, Animal* , Gastrointestinal Microbiome*/drug effects , MicroRNAs*/genetics , MicroRNAs*/metabolism, Animals ; Female ; Rats ; Ovary/drug effects ; Ovary/metabolism ; Ovary/pathology ; Probiotics ; Testosterone/blood ; Rats, Sprague-Dawley ; RNA, Ribosomal, 16S/genetics ; bcl-2-Associated X Protein/metabolism ; bcl-2-Associated X Protein/genetics

المؤلفون: Jin R; Department of Gynecology, Jiaojiang Maternal and Child Health Hospital, Taizhou City, China., Chen A; Department of Gynecology, Changxing People's Hospital of Chongming District, Shanghai, China., Ye Y; Department of Gynaecology, Lishui Hospital of Traditional Chinese Medicine, Lishui, China., Ren Y; Department of Gynecology, Huzhou Maternity & Child Health Care Hospital, Huzhou, China., Lu J; Department of Gynecology, Huzhou Maternity & Child Health Care Hospital, Huzhou, China., Xuan F; Department of Obstetrics and Gynecology, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou City, China., Zhou W; Department of Ultrasound, Jiaojiang Maternal and Child Health Hospital, Taizhou City, China.

المصدر: Molecular reproduction and development [Mol Reprod Dev] 2024 Aug; Vol. 91 (8), pp. e23768.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8903333 Publication Model: Print Cited Medium: Internet ISSN: 1098-2795 (Electronic) Linking ISSN: 1040452X NLM ISO Abbreviation: Mol Reprod Dev Subsets: MEDLINE

مواضيع طبية MeSH: Metformin*/pharmacology , Polycystic Ovary Syndrome*/metabolism , Polycystic Ovary Syndrome*/drug therapy , Polycystic Ovary Syndrome*/pathology , Autophagy*/drug effects , Berberine*/pharmacology , TOR Serine-Threonine Kinases*/metabolism , Proto-Oncogene Proteins c-akt*/metabolism , Signal Transduction*/drug effects, Female ; Animals ; Rats ; AMP-Activated Protein Kinases/metabolism ; Rats, Sprague-Dawley ; Granulosa Cells/drug effects ; Granulosa Cells/metabolism ; Granulosa Cells/pathology ; Insulin Resistance ; Ovary/drug effects ; Ovary/metabolism ; Ovary/pathology ; Drug Therapy, Combination ; Oxidative Stress/drug effects

المؤلفون: Hasegawa Y; Department of Obstetrics and Gynecology, Gunma University Graduate School of Medicine, Maebashi, Japan., Kitahara Y; Department of Obstetrics and Gynecology, Gunma University Graduate School of Medicine, Maebashi, Japan., Kobayashi M; Department of Obstetrics and Gynecology, Gunma University Graduate School of Medicine, Maebashi, Japan., Miida M; Department of Obstetrics and Gynecology, Gunma University Graduate School of Medicine, Maebashi, Japan., Nenoi H; Department of Obstetrics and Gynecology, Gunma University Graduate School of Medicine, Maebashi, Japan., Tsukui Y; Department of Obstetrics and Gynecology, Gunma University Graduate School of Medicine, Maebashi, Japan., Iizuka M; Department of Obstetrics and Gynecology, Gunma University Graduate School of Medicine, Maebashi, Japan., Hiraishi H; Department of Obstetrics and Gynecology, Gunma University Graduate School of Medicine, Maebashi, Japan., Nakazato S; Department of Obstetrics and Gynecology, Gunma University Graduate School of Medicine, Maebashi, Japan., Iwase A; Department of Obstetrics and Gynecology, Gunma University Graduate School of Medicine, Maebashi, Japan.

المصدر: The journal of obstetrics and gynaecology research [J Obstet Gynaecol Res] 2024 Aug; Vol. 50 (8), pp. 1289-1294. Date of Electronic Publication: 2024 May 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley on behalf of the Japan Society of Obstetrics and Gynecology] Country of Publication: Australia NLM ID: 9612761 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1447-0756 (Electronic) Linking ISSN: 13418076 NLM ISO Abbreviation: J Obstet Gynaecol Res Subsets: MEDLINE

مواضيع طبية MeSH: Polycystic Ovary Syndrome*/diagnosis , Polycystic Ovary Syndrome*/blood , Testosterone*/blood , Body Mass Index*, Humans ; Female ; Adolescent ; Young Adult ; Ovary/pathology ; Ovary/diagnostic imaging ; Adult

المؤلفون: Zhou N; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, China., Lv W; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, China., Chen L; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, China., Chen K; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, China., He Q; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, China., Xie G; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, China., Ma J; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, China., Cao Y; Department of Obstetrics and Gynecology, Xuzhou Central Hospital, Xuzhou Clinical School of Xuzhou Medical University, 199 South Jiefang Road, Xuzhou, 221004, China., Zhang B; Department of Obstetrics and Gynecology, Xuzhou Central Hospital, Xuzhou Clinical School of Xuzhou Medical University, 199 South Jiefang Road, Xuzhou, 221004, China. bettyzhang10@163.com., Zhou X; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, China. zxy851107@xzhmu.edu.cn.

المصدر: Reproductive sciences (Thousand Oaks, Calif.) [Reprod Sci] 2024 Aug; Vol. 31 (8), pp. 2234-2245. Date of Electronic Publication: 2024 Mar 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 101291249 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1933-7205 (Electronic) Linking ISSN: 19337191 NLM ISO Abbreviation: Reprod Sci Subsets: MEDLINE

مواضيع طبية MeSH: Polycystic Ovary Syndrome*/metabolism , Polycystic Ovary Syndrome*/drug therapy , Polycystic Ovary Syndrome*/chemically induced , Polycystic Ovary Syndrome*/pathology , Receptors, Aryl Hydrocarbon*/metabolism , Estrogens*/pharmacology , Estrogens*/metabolism , Cytochrome P-450 CYP1A2*/metabolism, Female ; Animals ; Humans ; Mice ; Cytochrome P-450 CYP1A1/metabolism ; Ovary/drug effects ; Ovary/metabolism ; Ovary/pathology ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Disease Models, Animal ; Adult

المؤلفون: Meng B; Laboratory Animal Center, Xi'an Jiaotong University Health Science Centre, Xi'an, Shaanxi, China.; Center for Reproductive Medicine, Xi'an Angel Women's & Children's Hospital, Xi'an, China., Yang X; Medical Imaging Department, Yangling Demonstration Area Hospital, Yangling, China., Luo S; State Key Laboratory of Oncology in South China, Sun Yat-sen University, Guangzhou, China., Shen C; Department of Orthopedics, The Second Affiliated Hospital of Nantong University, Nantong, Jiangsu, China., Qi J; Laboratory Animal Center, Xi'an Jiaotong University Health Science Centre, Xi'an, Shaanxi, China., Zhang H; Department of Pathology, Xi'an International Medical Center Hospital, Xi'an, Shaanxi, China., Li Y; Department of Pathology, Xi'an International Medical Center Hospital, Xi'an, Shaanxi, China., Xue Y; Laboratory Animal Center, Xi'an Jiaotong University Health Science Centre, Xi'an, Shaanxi, China., Zhao J; Laboratory Animal Center, Xi'an Jiaotong University Health Science Centre, Xi'an, Shaanxi, China.; Department of Hematology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China., Qu P; Laboratory Animal Center, Xi'an Jiaotong University Health Science Centre, Xi'an, Shaanxi, China., Liu E; Laboratory Animal Center, Xi'an Jiaotong University Health Science Centre, Xi'an, Shaanxi, China.

المصدر: Molecular reproduction and development [Mol Reprod Dev] 2024 Aug; Vol. 91 (8), pp. e23720. Date of Electronic Publication: 2023 Dec 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8903333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-2795 (Electronic) Linking ISSN: 1040452X NLM ISO Abbreviation: Mol Reprod Dev Subsets: MEDLINE

مواضيع طبية MeSH: Polycystic Ovary Syndrome*/metabolism , Polycystic Ovary Syndrome*/pathology , Disease Models, Animal*, Female ; Animals ; Mice ; Proteomics/methods ; Ovary/metabolism ; Ovary/pathology ; Lipid Metabolism ; Oxidative Stress ; Proteome/metabolism

المؤلفون: Sarvestani M; Physiology Research Center, Kashan University of Medical Sciences, Kashan, Iran., Rajabzadeh A; Department of Applied Cell Sciences, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran. rajabzadeh-a@kaums.ac.ir.; Anatomical Sciences Research Center, Kashan University of Medical Sciences, Kashan, Iran. rajabzadeh-a@kaums.ac.ir., Mazoochi T; Department of Applied Cell Sciences, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran. mazoochi45@yahoo.com.; Anatomical Sciences Research Center, Kashan University of Medical Sciences, Kashan, Iran. mazoochi45@yahoo.com., Samimi M; Department of obstetrics and gynecology, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran., Navari M; Department of Medical Biotechnology, School of Paramedical Sciences, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran.; Research Center of Advanced Technologies in Medicine, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran., Moradi F; Tissue Engineering and Applied Cell Sciences Division, Department of Anatomical Sciences, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.; Biobank of Research, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.

المصدر: BMC endocrine disorders [BMC Endocr Disord] 2024 Aug 19; Vol. 24 (1), pp. 154. Date of Electronic Publication: 2024 Aug 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101088676 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-6823 (Electronic) Linking ISSN: 14726823 NLM ISO Abbreviation: BMC Endocr Disord Subsets: MEDLINE

مواضيع طبية MeSH: Polycystic Ovary Syndrome*/therapy , Polycystic Ovary Syndrome*/metabolism , Rats, Wistar* , Disease Models, Animal* , Placenta*/metabolism , Mesenchymal Stem Cell Transplantation*/methods , Mesenchymal Stem Cells*/metabolism, Animals ; Female ; Rats ; Pregnancy ; Ovary/metabolism ; Metabolome ; Insulin Resistance