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1
المؤلفون: Masahiro Hiasa, Tatsuo Okui, Toshiyuki Yoneda, Shoji Ryumon, Yuki Kunisada, Akira Sasaki, Fletcher A. White, Kisho Ono, Soichiro Ibaragi, G. David Roodman
المصدر: Journal of Bone Oncology
Journal of Bone Oncology, Vol 26, Iss, Pp 100330-(2021)مصطلحات موضوعية: 4T1/sh HMGB1 mice, mice intratibially inoculated with 4T1 BC/sh HMGB1 cells, 0301 basic medicine, lcsh:Diseases of the musculoskeletal system, DAMP, damage-associated molecular pattern, M-CSF, macrophage colony-stimulating factor, CGRP, calcitonin gene-related peptide, DbcAMP, dibutyryl cyclic AMP, RAGE (receptor), Small hairpin RNA, Bone pain, 0302 clinical medicine, Breast cancer, ERK, extracellular signal-regulated kinase, Medicine, TRL, toll-like receptor, Receptor, HMGB1, TRAP, tartrate-resistant acid phosphatase, biology, Bone metastasis, pCREB, phosphorylated CREB, MNOCs, multinucleated osteoclast-like cells, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, DRG, dorsal root ganglion, RAGE, CREB, cyclic AMP-responsive element-binding protein, Oncology, 030220 oncology & carcinogenesis, pERK, phosphorylated ERK, medicine.symptom, Research Article, RAGE, receptor for advanced glycation end products, Sensory neurons, Neurite, BC, breast cancer, chemical and pharmacologic phenomena, RANKL, receptor activator of NF-κB ligand, lcsh:RC254-282, 03 medical and health sciences, CM, conditioned medium, 4T1 mice, mice intratibially inoculated with 4T1 BC cells, BCABP, breast cancer-associated bone pain, ComputingMethodologies_COMPUTERGRAPHICS, ALP, alkaline phosphatase, SN, sensory neuron, business.industry, 4T1/sh control mice, mice intratibially inoculated with 4T1 BC/sh control cells, medicine.disease, HMGB1, high mobility group box 1, 030104 developmental biology, biology.protein, Cancer research, TLR4, lcsh:RC925-935, business
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المؤلفون: Emma V. Bird, Veselin I. Andreev, Anne King, Claire R. Christmas, Fiona M. Boissonade, Ilona Obara, Tommaso Iannitti
المصدر: Neuroscience
مصطلحات موضوعية: Male, 0301 basic medicine, Nervous system, trigeminal nucleus, Gene Expression, Trigeminal Nuclei, p38 Mitogen-Activated Protein Kinases, CGRP, calcitonin gene-related peptide, Rats, Sprague-Dawley, Tissue Culture Techniques, PCR, polymerase chain reaction, 0302 clinical medicine, ERK, extracellular signal-regulated kinase, NDS, normal donkey serum, Vc, trigeminal subnucleus caudalis, Cy3, indocarbocyanine, p38, p38 MAPK, lymphotactin, VGlut1, vesicular glutamate transporter 1, Extracellular Signal-Regulated MAP Kinases, Neurons, IB4, isolectin B4, Chemistry, General Neuroscience, orofacial pain, 3. Good health, Cell biology, aCSF, artificial cerebrospinal fluid, medicine.anatomical_structure, pp38, phosphorylated p38, Female, Receptors, Chemokine, pERK, phosphorylated ERK, medicine.symptom, Iba1, ionized calcium-binding adapter molecule 1, Proto-Oncogene Proteins c-fos, vMIP-II, viral CC chemokine macrophage inhibitory protein-II, CCI, chronic constriction injury, PBS, phosphate-buffered saline, Schwann cell, Calcitonin gene-related peptide, Article, OLIG2, 03 medical and health sciences, Facial Pain, medicine, Animals, Trigeminal Nerve, PBST, PBS containing Triton-X, TTX, tetrodotoxin, XCR1, lymphotactin receptor, Rats, Wistar, neuronal excitability, Trigeminal nerve, chemokine, GFAP, glial fibrillary acidic protein, Nerve injury, Oligodendrocyte, XCL1, lymphotactin, Chemokines, C, 030104 developmental biology, RT–PCR, reverse transcriptase–PCR, Neuralgia, Trigeminal Nerve Injuries, nerve injury, PFA, paraformaldehyde, VGlut2, vesicular glutamate transporter 2, MAPK, mitogen-activated protein kinase, 030217 neurology & neurosurgery, XCL1
وصف الملف: application/pdf
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المؤلفون: Jia Zhang, Klaus H. Kaestner, Kristy Ou, Zhao V. Wang, Phillipp Scherer, Yang Jiao
المصدر: Molecular Metabolism
Molecular Metabolism, Vol 11, Iss, Pp 212-217 (2018)مصطلحات موضوعية: 0301 basic medicine, Male, lcsh:Internal medicine, ST5 OE, ST5-overexpressing, rtTA, reverse tetracycline-controlled transactivator, ST5, Suppression of Tumorigenicity 5, Biology, Brief Communication, STZ, streptozotocin, Diabetes Mellitus, Experimental, 03 medical and health sciences, Mice, Downregulation and upregulation, Epidermal growth factor, Insulin-Secreting Cells, β-cell proliferation, medicine, Animals, lcsh:RC31-1245, Molecular Biology, MODY, Maturity Onset Diabetes of the Young, PDGF, Platelet-Derived Growth Factor, Cell Proliferation, Doxycycline, geography, geography.geographical_feature_category, Ras/ERK signaling, RIP, Rat Insulin Promoter, Cell growth, Activator (genetics), ST5 (Suppression Of Tumorigenicity 5), GEF, Guanine Nucleotide Exchange Factor, Tumor Suppressor Proteins, Diabetes, Cell Biology, Islet, Streptozotocin, Up-Regulation, DNA-Binding Proteins, Mice, Inbred C57BL, EGF, Epidermal Growth Factor, 030104 developmental biology, Cancer research, Female, TRE, Tetracycline Response Element, Signal transduction, pERK, phosphorylated ERK, medicine.drug, Signal Transduction
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المؤلفون: Zhigang Li, Swetha Parvathaneni, David B. Sacks
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Scaffold protein, calmodulin, Calmodulin, IQGAP1, IQ motif–containing GTPase-activating protein, MAP Kinase Signaling System, NGF, nerve growth factor, DMSO, dimethyl sulfoxide, MAPK cascade, Biochemistry, DMEM, Dulbecco’s modified Eagle’s medium, GST, glutathione S-transferase, PVDF, polyvinylidene difluoride, Mice, 03 medical and health sciences, IQGAP1, ERK, extracellular signal-regulated kinase, FBS, fetal bovine serum, Animals, mitogen-activated protein kinase (MAPK), Protein kinase A, kinase suppressor of Ras1 (KSR1), KSR1, kinase suppressor of Ras1, Molecular Biology, SDS-PAGE, sodium dodecyl sulfate–polyacrylamide gel electrophoresis, EGF, epidermal growth factor, calcium, 030102 biochemistry & molecular biology, biology, PLA, proximity ligation assay, Chemistry, Kinase, Cell Biology, [Ca2+]i, intracellular free Ca2+ concentration, MEF, mouse embryonic fibroblast, Cell biology, protein–protein interaction, 030104 developmental biology, biology.protein, EGTA, ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid, pERK, phosphorylated ERK, Mitogen-Activated Protein Kinases, Signal transduction, signaling, Protein Kinases, MAPK, mitogen-activated protein kinase, Research Article, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb5ad95f95365dd536734a798b71634
https://doi.org/10.1016/j.jbc.2021.100577 -
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المؤلفون: Andrew F. Hill, Ashley I. Bush, Hongyun Li, Brett Garner, Ya Hui Hung, Genevieve Evin
المصدر: Clinical Science (London, England : 1979)
مصطلحات موضوعية: MAPK/ERK pathway, Small interfering RNA, Pyrrolidines, CHO cell, Chinese-hamster ovary cell, amyloid precursor protein, Propanolamines, Amyloid beta-Protein Precursor, chemistry.chemical_compound, 0302 clinical medicine, Cricetinae, Amyloid precursor protein, Enzyme Inhibitors, RNA, Small Interfering, EtDO-P4, D-threo-ethylenedioxy-1-phenyl-2-palmitoylamino-3-pyrrolidino-1-propanol, GCS, glucosylceramide synthase, 0303 health sciences, extracellular-signal-regulated kinase (ERK), glycosphingolipid, biology, PDMP, D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol, Kinase, General Medicine, Alzheimer's disease, Recombinant Proteins, Biochemistry, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, Glucosyltransferases, Gene Knockdown Techniques, PPMP, D-threo-1-phenyl-2-hexadecanoylamino-3-morpholino-1-propanol, Phosphorylation, AD, Alzheimer's disease, pERK, phosphorylated ERK, BACE-1, β-site APP-cleaving enzyme, Research Article, GSL, glycosphingolipid, Ceramide, GlcCer, glucosylceramide, MAP Kinase Signaling System, Morpholines, S7, sAPPα, soluble APPα fragment, Amyloidogenic Proteins, CHO Cells, ERK, extracellular-signal-regulated kinase, Ceramides, Aβ42, Aβ-(1–42), Glycosphingolipids, Cell Line, amyloid β-peptide, 03 medical and health sciences, Cricetulus, FBS, fetal bovine serum, PS, presenilin, APP, amyloid precursor protein, Aβ, amyloid β-peptide, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-2H-tetrazolium bromide, Animals, Humans, Gamma secretase, 030304 developmental biology, Sphingolipids, Amyloid beta-Peptides, Base Sequence, Aβ40, Aβ-(1–40), Sphingolipid, chemistry, 2AA, 2-anthranilic acid, siRNA, small interfering RNA, DAPT, N-[N-(3,5-difluorophenacetyl)-L-alanyl]-(S)-phenylglycine t-butyl ester, biology.protein, LacCer, lactosylceramide, MAPK, mitogen-activated protein kinase, 030217 neurology & neurosurgery
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c24285a2061a30e90e2eb64b6b91e72
https://doi.org/10.1042/cs20110257 -
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المؤلفون: M A, Worsley, C E, Allen, A, Billinton, A E, King, F M, Boissonade
المصدر: Neuroscience
مصطلحات موضوعية: Photomicrography, endocrine system, chronic inflammation, trigeminal nucleus, AOI, area of interest, PBS, phosphate-buffered saline, Cell Count, CFA, complete Freund’s adjuvant, p38 Mitogen-Activated Protein Kinases, NeuN, neuron-specific nuclear protein, Article, Trigeminal Caudal Nucleus, JOR, Jaw-opening reflex, pERK, ERK, extracellular signal-regulated kinase, NDS, normal donkey serum, Vc, trigeminal subnucleus caudalis, Physical Stimulation, Animals, Cy3, indocarbocyanine, pain, Phosphorylation, p38, p38 MAPK, Extracellular Signal-Regulated MAP Kinases, Dental Pulp, ANOVA, analysis of variance, PBST, phosphate-buffered saline containing Triton-X, Neurons, Ferrets, GFAP, glial fibrillary acidic protein, Pulpitis, pp38, Immunohistochemistry, MAPK, NGS, normal goat serum, Disease Models, Animal, EMG, electromyogram, Microscopy, Fluorescence, pp38, phosphorylated p38, Astrocytes, Female, FITC, fluorescein isothiocyanate, Chronic Pain, pERK, phosphorylated ERK, Proto-Oncogene Proteins c-fos, MAPK, mitogen-activated protein kinase
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7دورية أكاديمية
المؤلفون: Okui T; Department of Oral and Maxillofacial Surgery and Biopathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama, Japan.; Department of Medicine, Hematology Oncology, Indiana University School of Medicine, Indianapolis, IN, USA., Hiasa M; Department of Biomaterials and Bioengineerings, University of Tokushima Graduate School of Dentistry, Tokushima, Japan.; Department of Medicine, Hematology Oncology, Indiana University School of Medicine, Indianapolis, IN, USA., Ryumon S; Department of Oral and Maxillofacial Surgery and Biopathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama, Japan., Ono K; Department of Oral and Maxillofacial Surgery and Biopathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama, Japan., Kunisada Y; Department of Oral and Maxillofacial Surgery and Biopathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama, Japan., Ibaragi S; Department of Oral and Maxillofacial Surgery and Biopathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama, Japan., Sasaki A; Department of Oral and Maxillofacial Surgery and Biopathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama, Japan., Roodman GD; Department of Medicine, Hematology Oncology, Indiana University School of Medicine, Indianapolis, IN, USA.; The Rodebusch VA, Indianapolis, IN, USA., White FA; Department of Anesthesia, Paul and Carole Stark Neurosciences Research Institute, Indianapolis, IN, USA., Yoneda T; Department of Medicine, Hematology Oncology, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Cellular and Molecular Biochemistry, Osaka University Graduate School of Dentistry, Osaka, Japan.
المصدر: Journal of bone oncology [J Bone Oncol] 2020 Oct 28; Vol. 26, pp. 100330. Date of Electronic Publication: 2020 Oct 28 (Print Publication: 2021).
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101610292 Publication Model: eCollection Cited Medium: Print ISSN: 2212-1366 (Print) Linking ISSN: 22121366 NLM ISO Abbreviation: J Bone Oncol Subsets: PubMed not MEDLINE