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المصدر: NeuroImage 163, 150-159 (2017). doi:10.1016/j.neuroimage.2017.09.042
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Aging, Pathology, medicine.medical_specialty, Cognitive Neuroscience, Central nervous system, Substantia nigra, Biology, methods [Brain Mapping], Young Adult, 03 medical and health sciences, pathology [Aging], methods [Magnetic Resonance Imaging], 0302 clinical medicine, Neuromelanin, Neuroimaging, medicine, Humans, Aging brain, ddc:610, Aged, pathology [Locus Coeruleus], Aged, 80 and over, Brain Mapping, medicine.diagnostic_test, Magnetic resonance imaging, Middle Aged, Magnetic Resonance Imaging, 030104 developmental biology, medicine.anatomical_structure, Neurology, Locus coeruleus, Female, Locus Coeruleus, Brainstem, diagnostic imaging [Locus Coeruleus], Neuroscience, 030217 neurology & neurosurgery
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المؤلفون: Isidro Ferrer, Waqas Tahir, Pol Andrés-Benito, Franc Llorens, Eulàlia Martí, Belén Ansoleaga, Katrin Thüne, Karina Hernández-Ortega, Inga Zerr
المصدر: Journal of molecular neuroscience 63(2), 206-215 (2017). doi:10.1007/s12031-017-0971-4
مصطلحات موضوعية: Male, 0301 basic medicine, Pathology, Hippocampus, genetics [Alzheimer Disease], metabolism [Hippocampus], pathology [Alzheimer Disease], 0302 clinical medicine, metabolism [MicroRNAs], Entorhinal Cortex, genetics [MicroRNAs], Aged, 80 and over, Neurofibrillary Tangles, General Medicine, Middle Aged, metabolism [Neurofibrillary Tangles], medicine.anatomical_structure, Cerebral cortex, Locus Coeruleus, Female, Alzheimer's disease, Psychology, metabolism [Alzheimer Disease], medicine.medical_specialty, In situ hybridization, metabolism [Locus Coeruleus], 03 medical and health sciences, Cellular and Molecular Neuroscience, Alzheimer Disease, medicine, Humans, ddc:610, Aged, pathology [Locus Coeruleus], Dentate gyrus, Neurofibrillary tangle, pathology [Entorhinal Cortex], Entorhinal cortex, medicine.disease, MicroRNAs, pathology [Hippocampus], 030104 developmental biology, Case-Control Studies, Locus coeruleus, metabolism [Entorhinal Cortex], pathology [Neurofibrillary Tangles], Neuroscience, 030217 neurology & neurosurgery
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المؤلفون: Liu, Kathy Y, Acosta-Cabronero, Julio, Howard, Robert, Hämmerer, Dorothea, Cardenas-Blanco, Arturo, Loane, Clare, Berry, Alex J, Betts, Matthew J, Kievit, Rogier A, Henson, Richard N, Düzel, Emrah, Cam-CAN
المساهمون: Kievit, Rogier [0000-0003-0700-4568], Henson, Rik [0000-0002-0712-2639], Apollo - University of Cambridge Repository
المصدر: Neurobiology of aging 74, 101-111 (2019). doi:10.1016/j.neurobiolaging.2018.10.014
Neurobiology of Agingمصطلحات موضوعية: Adult, Aged, 80 and over, pathology [Locus Coeruleus], Male, Melanins, Aging, Adolescent, Noradrenergic system, Middle Aged, Magnetic Resonance Imaging, Article, Neuromelanin, Healthy Aging, Young Adult, Cognition, pathology [Healthy Aging], psychology [Healthy Aging], Locus coeruleus, Humans, Female, ddc:610, neuromelanin, diagnostic imaging [Locus Coeruleus], Aged
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b48582006637d18966e7851977c4b488
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المؤلفون: Koji Yamanaka, Jari Koistinaho, Douglas T. Golenbock, Terrence Town, Guy C. Brown, Erik Boddeke, Monica J. Carson, V. Hugh Perry, Gabor C. Petzold, Olga Garaschuk, David J. Brooks, Markus P. Kummer, John C.S. Breitner, Nikolaus Deigendesch, Frederic Brosseron, Greg M. Cole, Nicolas G. Bazan, Stéphane Hunot, Michael T. Heneka, Dave Morgan, Javier Vitorica, Gary E. Landreth, Clive Holmes, Eicke Latz, Bertrand Joseph, Annett Halle, Charles A. Dinarello, Mari L. Shinohara, Joseph El Khoury, Douglas L. Feinstein, Andreas H. Jacobs, Tony Wyss-Coray, Alexei Verkhratsky, Karl Herrup, Richard M. Ransohoff, Sally A. Frautschy, Bente Finsen
المصدر: The Lancet. Neurology, vol 14, iss 4
ResearcherID
The lancet/ Neurology 14(4), 388-405 (2015). doi:10.1016/S1474-4422(15)70016-5
Lancet Neurology, 14, 388-405
Heneka, MT; Carson, MJ; Khoury, JE; Landreth, GE; Brosseron, F; Feinstein, DL; et al.(2015). Neuroinflammation in Alzheimer's disease. The Lancet Neurology, 14(4), 388-405. doi: 10.1016/S1474-4422(15)70016-5. UCLA: Retrieved from: http://www.escholarship.org/uc/item/99h2f9m1
Lancet Neurology, 14, 4, pp. 388-405
Heneka, M T, Carson, M J, Khoury, J E, Landreth, G E, Brosseron, F, Feinstein, D L, Jacobs, A H, Wyss-Coray, T, Vitorica, J, Ransohoff, R M, Herrup, K, Frautschy, S A, Finsen, B, Brown, G C, Verkhratsky, A, Yamanaka, K, Koistinaho, J, Latz, E, Halle, A, Petzold, G C, Town, T, Morgan, D, Shinohara, M L, Perry, V H, Holmes, C, Bazan, N G, Brooks, D J, Hunot, S, Joseph, B, Deigendesch, N, Garaschuk, O, Boddeke, E, Dinarello, C A, Breitner, J C, Cole, G M, Golenbock, D T & Kummer, M P 2015, ' Neuroinflammation in Alzheimer's disease ', Lancet Neurology, vol. 14, no. 4, pp. 388-405 . https://doi.org/10.1016/S1474-4422(15)70016-5
The Lancet Neurologyمصطلحات موضوعية: Aging, MILD COGNITIVE IMPAIRMENT, lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Disease, Alzheimer's Disease, Systemic inflammation, Severity of Illness Index, Inflammation/diagnosis, immunology [Inflammation], Aetiology, metabolism [Inflammation], blood [Biomarkers], Microglia, complications [Obesity], pathology [Microglia], RANDOMIZED CONTROLLED-TRIAL, immunology [Microglia], Disease Progression, Locus Coeruleus, Anti-Inflammatory Agents, Non-Steroidal/therapeutic use, Central nervous system, Clinical Sciences, CEREBRAL AMYLOID ANGIOPATHY, Article, administration & dosage [Nootropic Agents], Phagocytosis, Alzheimer Disease, Humans, Inflammation Mediators/immunology, NITRIC-OXIDE SYNTHASE, GENOME-WIDE ASSOCIATION, Locus Coeruleus/pathology, pathology [Locus Coeruleus], Animal, Prevention, Inflammatory and immune system, CENTRAL-NERVOUS-SYSTEM, Immunity, Immunity, Innate, diagnosis [Inflammation], immunology [Alzheimer Disease], nervous system, Astrocytes, Brain Injuries, Immunology, Dementia, Neurology (clinical), Obesity/complications, Neuroscience, Biomarkers, Protein Folding, Microglia/immunology, Anti-Inflammatory Agents, genetics [Alzheimer Disease], Neurodegenerative, prevention & control [Alzheimer Disease], pathology [Alzheimer Disease], Risk Factors, Brain Injuries/complications, complications [Brain Injuries], 2.1 Biological and endogenous factors, Innate, Nootropic Agents, therapeutic use [Anti-Inflammatory Agents, Non-Steroidal], pathology [Astrocytes], Clinical Trials as Topic, Nootropic Agents/administration & dosage, Anti-Inflammatory Agents, Non-Steroidal, Pattern recognition receptor, medicine.anatomical_structure, cerebrospinal fluid [Biomarkers], Neurological, medicine.symptom, Inflammation Mediators, immunology [Inflammation Mediators], Non-Steroidal, metabolism [Alzheimer Disease], Astrocytes/immunology, ANTIINFLAMMATORY PREVENTION TRIAL, TRAUMATIC BRAIN-INJURY, immunology [Astrocytes], metabolism [Brain Injuries], POSITRON-EMISSION-TOMOGRAPHY, metabolism [Obesity], Acquired Cognitive Impairment, medicine, Animals, ddc:610, Obesity, TRANSGENIC MOUSE MODEL, Neuroinflammation, Inflammation, Alzheimer Disease/genetics, Innate immune system, Neurology & Neurosurgery, business.industry, metabolism [Inflammation Mediators], Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Brain Disorders, Disease Models, Animal, Disease Models, Immunization, business, Biomarkers/blood
وصف الملف: application/pdf
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المؤلفون: Michael T. Heneka, Monika Stoll, Gregor Eichele, Hans-Christian Pape, Markus P. Kummer, Stephanie Schwartz, Joachim L. Schultze, David Weinshenker, Thea Hammerschmidt, Stefanie Figura, Anika Witten, Ana Martinez, Dick Terwel
المصدر: Journal of Neuroscience
The journal of neuroscience 34(26), 8845-8854 (2014). doi:10.1523/JNEUROSCI.4027-13.2014مصطلحات موضوعية: Hippocampus, locus ceruleus, memory, Amyloid beta-Protein Precursor, Mice, Norepinephrine, genetics [Memory Disorders], metabolism [Amyloid beta-Protein Precursor], Amyloid precursor protein, metabolism [Nerve Degeneration], Mice, Knockout, Neurons, biology, metabolism [Presenilin-1], Chemistry, General Neuroscience, Neurodegeneration, neurodegeneration, metabolism [Memory Disorders], pathology [Nerve Degeneration], Long-term potentiation, genetics [Presenilin-1], Articles, genetics [Eosinophil-Derived Neurotoxin], genetics [Amyloid beta-Protein Precursor], metabolism [Neurons], genetics [Nerve Degeneration], NMDA receptor, Locus Coeruleus, medicine.medical_specialty, presenilin 1, mouse, Mice, Transgenic, Eosinophil-Derived Neurotoxin, metabolism [Locus Coeruleus], Receptors, N-Methyl-D-Aspartate, Presenilin, Ear2 protein, mouse, physiology [Maze Learning], Internal medicine, Ca2+/calmodulin-dependent protein kinase, genetics [Receptors, N-Methyl-D-Aspartate], mental disorders, medicine, Presenilin-1, Animals, Learning, ddc:610, physiology [Learning], metabolism [Receptors, N-Methyl-D-Aspartate], Maze Learning, physiology [Memory], pathology [Locus Coeruleus], Memory Disorders, metabolism [Norepinephrine], NR2B NMDA receptor, medicine.disease, Endocrinology, nervous system, Nerve Degeneration, biology.protein, Alzheimer, noradrenaline, Locus coeruleus, metabolism [Eosinophil-Derived Neurotoxin], Neuroscience
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07aa351b64b44747d3df90e1ce8bcba3
https://zenodo.org/record/16482 -
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المؤلفون: Tommy Regen, Daniel Jardanhazi-Kurutz, Fabian Nadrigny, Uwe-Karsten Hanisch, Markus P. Kummer, Lucia Dumitrescu-Ozimek, Michael T. Heneka, Ana Martinez-Hernandez, Frank Kirchhoff, Jochen Walter, Dick Terwel
المصدر: Proceedings of the National Academy of Sciences of the United States of America 107(13), 6058-6063 (2010). doi:10.1073/pnas.0909586107
Proceedings of the National Academy of Sciences of the United States of Americaمصطلحات موضوعية: Pathology, Chemokine, Transcription, Genetic, metabolism [Recombinant Proteins], genetics [Alzheimer Disease], metabolism [Microglia], drug effects [Microglia], pathology [Alzheimer Disease], Amyloid beta-Protein Precursor, Mice, Norepinephrine, pathology [Brain], Cell Movement, metabolism [Amyloid beta-Protein Precursor], drug effects [Cell Movement], metabolism [Inflammation], Multidisciplinary, Microglia, pathology [Microglia], Brain, Recombinant Proteins, genetics [Recombinant Proteins], medicine.anatomical_structure, genetics [Amyloid beta-Protein Precursor], Cytokines, Female, Locus Coeruleus, ddc:500, physiology [Phagocytosis], medicine.symptom, Chemokines, physiology [Cell Movement], metabolism [Alzheimer Disease], medicine.drug, medicine.medical_specialty, Phagocytosis, metabolism [Amyloid beta-Peptides], Inflammation, Mice, Transgenic, deficiency [Norepinephrine], Biology, drug effects [Phagocytosis], In Vitro Techniques, metabolism [Locus Coeruleus], Cell Line, genetics [Inflammation], Alzheimer Disease, medicine, Animals, Humans, biosynthesis [Chemokines], Neuroinflammation, pathology [Inflammation], pathology [Locus Coeruleus], metabolism [Norepinephrine], Amyloid beta-Peptides, Locus Ceruleus, biosynthesis [Cytokines], Disease Models, Animal, metabolism [Brain], pharmacology [Norepinephrine], biology.protein, Locus coeruleus
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc802921fed46432568c030bee61e421
https://pubmed.ncbi.nlm.nih.gov/20419860
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