المؤلفون: Fernando A. Batista, Soraya S. Bosch, Sabine Butzloff, Sergey Lunev, Kamila A. Meissner, Marleen Linzke, Atilio R. Romero, Chao Wang, Ingrid B. Müller, Alexander S. S. Dömling, Matthew R. Groves, Carsten Wrenger

المصدر: MicrobiologyOpen, Vol 8, Iss 7, Pp n/a-n/a (2019)

مصطلحات موضوعية: drug target validation, oligomeric state, phenotypic mapping, Plasmodium falciparum, structural biology, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-8827

URL الوصول: https://doaj.org/article/b2750bae516e4b6997925ef758050641

المصدر: Expert Opinion on Drug Discovery. 15(2):189-202

مصطلحات موضوعية: BLOOD STAGES, PLASMODIUM-VIVAX DHFR, Protein oligomerisation, malaria, DRUG TARGET, LEAD OPTIMIZATION, TRANSGENE EXPRESSION, phenotypic mapping, FALCIPARUM DIHYDROOROTATE DEHYDROGENASE, MALARIA PARASITES, drug target validation, PIPERAQUINE RESISTANCE, NEGATIVE SELECTION, GENE-EXPRESSION

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dris___01423::a596c3815e6ff37ee9e453297e7fc3c2
https://research.rug.nl/en/publications/af981d6a-2596-4373-82f2-ea974e442613

المؤلفون: Juliana F Vilacha, Fernando de Assis Batista, Carsten Wrenger, Sergey Lunev, Soraya S Bosch, Benjamin Gyau, Matthew Groves

المصدر: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

مصطلحات موضوعية: BLOOD STAGES, Plasmodium, PLASMODIUM-VIVAX DHFR, Computer science, Population, Drug target, Druggability, Aspartate metabolism, Computational biology, Validation Studies as Topic, LEAD OPTIMIZATION, TRANSGENE EXPRESSION, Antimalarials, 03 medical and health sciences, 0302 clinical medicine, Drug Development, MALARIA PARASITES, Drug Discovery, medicine, Animals, Humans, education, PIPERAQUINE RESISTANCE, NEGATIVE SELECTION, GENE-EXPRESSION, 030304 developmental biology, 0303 health sciences, education.field_of_study, Drug discovery, Protein oligomerisation, DRUG TARGET, POLIPEPTÍDEOS, medicine.disease, Malaria, Drug development, phenotypic mapping, FALCIPARUM DIHYDROOROTATE DEHYDROGENASE, Proof of concept, 030220 oncology & carcinogenesis, drug target validation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa441dc06eb1da8d3efd735dafa160e

المؤلفون: Atilio Reyes Romero, Carsten Wrenger, Sergey Lunev, Chao Wang, Marleen Linzke, Soraya S Bosch, Sabine Butzloff, Kamila Anna Meissner, Alexander Dömling, Fernando de Assis Batista, Matthew Groves, Ingrid B. Müller

المساهمون: Drug Design, Medicinal Chemistry and Bioanalysis (MCB)

المصدر: MicrobiologyOpen
MicrobiologyOpen, 8(7):e779. Wiley
MicrobiologyOpen, Vol 8, Iss 7, Pp n/a-n/a (2019)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

مصطلحات موضوعية: AMINOTRANSFERASE, Plasmodium falciparum, Mutant, lcsh:QR1-502, Druggability, PURINE, Computational biology, Biology, METABOLISM, Microbiology, lcsh:Microbiology, MECHANISMS, 03 medical and health sciences, 0302 clinical medicine, In vivo, structural biology, Gene, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, oligomeric state, Original Articles, ANTIMALÁRICOS, biology.organism_classification, GENE, 3. Good health, Enzyme, chemistry, Structural biology, phenotypic mapping, Original Article, drug target validation, 030217 neurology & neurosurgery, Function (biology), INTERFACES

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ffbccf06d28255ac3b7e7ff4edebcfc
https://doi.org/10.1002/mbo3.779

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