المؤلفون: de Souza GR; Laboratory of Technology for Biodiversity in Health, Institute of Drug Technology, Oswaldo Cruz Foundation, Rua Sizenando Nabuco 100, Manguinhos, Rio de Janeiro 21041-250, RJ, Brazil., Mazzei JL; Laboratory of Technology for Biodiversity in Health, Institute of Drug Technology, Oswaldo Cruz Foundation, Rua Sizenando Nabuco 100, Manguinhos, Rio de Janeiro 21041-250, RJ, Brazil., Tostes JBF; Laboratory of Technology for Biodiversity in Health, Institute of Drug Technology, Oswaldo Cruz Foundation, Rua Sizenando Nabuco 100, Manguinhos, Rio de Janeiro 21041-250, RJ, Brazil., de Carvalho ALD; Laboratory of Technology for Biodiversity in Health, Institute of Drug Technology, Oswaldo Cruz Foundation, Rua Sizenando Nabuco 100, Manguinhos, Rio de Janeiro 21041-250, RJ, Brazil., Costa TEMM; Laboratory of Applied Pharmacology, Institute of Drug Technology, Oswaldo Cruz Foundation, Rua Sizenando Nabuco 100, Manguinhos, Rio de Janeiro 21041-250, RJ, Brazil; Center for Technological Development in Health (CDTS), Oswaldo Cruz Foundation, Rio de Janeiro, Brazil. Avenida Brasil 4036, room 814, Manguinhos, Rio de Janeiro 21040-361, RJ, Brazil., Penido C; Laboratory of Applied Pharmacology, Institute of Drug Technology, Oswaldo Cruz Foundation, Rua Sizenando Nabuco 100, Manguinhos, Rio de Janeiro 21041-250, RJ, Brazil; Center for Technological Development in Health (CDTS), Oswaldo Cruz Foundation, Rio de Janeiro, Brazil. Avenida Brasil 4036, room 814, Manguinhos, Rio de Janeiro 21040-361, RJ, Brazil., Siani AC; Laboratory of Technology for Biodiversity in Health, Institute of Drug Technology, Oswaldo Cruz Foundation, Rua Sizenando Nabuco 100, Manguinhos, Rio de Janeiro 21041-250, RJ, Brazil. Electronic address: antonio.siani@fiocruz.br.

المصدر: Fitoterapia [Fitoterapia] 2024 Jul; Vol. 176, pp. 105987. Date of Electronic Publication: 2024 May 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE

مواضيع طبية MeSH: Euphorbia*/chemistry , Latex*/chemistry , Phorbol Esters*/pharmacology, Humans ; Mice ; Animals ; Cell Line, Tumor ; Molecular Structure ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Brazil ; Monocytes/drug effects ; Phytochemicals/pharmacology ; Phytochemicals/isolation & purification ; Cell Survival/drug effects ; Diterpenes/pharmacology ; Diterpenes/isolation & purification ; Terpenes/pharmacology ; Terpenes/isolation & purification ; Antineoplastic Agents, Phytogenic/pharmacology ; Antineoplastic Agents, Phytogenic/isolation & purification ; Tetradecanoylphorbol Acetate ; Melanoma/drug therapy

المؤلفون: Yin Y; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, 500 W. 12th Ave., Columbus, Ohio 43210, United States., Zhao SL; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, 500 W. 12th Ave., Columbus, Ohio 43210, United States., Rane D; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, 500 W. 12th Ave., Columbus, Ohio 43210, United States., Lin Z; The Ohio State University Comprehensive Cancer Center─Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, 460 W. 10th Ave., Columbus, Ohio 43210, United States., Wu M; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, 500 W. 12th Ave., Columbus, Ohio 43210, United States.; The Ohio State University Comprehensive Cancer Center─Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, 460 W. 10th Ave., Columbus, Ohio 43210, United States., Peterson BR; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, 500 W. 12th Ave., Columbus, Ohio 43210, United States.; The Ohio State University Comprehensive Cancer Center─Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, 460 W. 10th Ave., Columbus, Ohio 43210, United States.

المصدر: Journal of the American Chemical Society [J Am Chem Soc] 2024 Jan 10; Vol. 146 (1), pp. 187-200. Date of Electronic Publication: 2023 Dec 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

مواضيع طبية MeSH: Protein Kinase C*/chemistry , Phorbol Esters*, Humans ; HEK293 Cells ; Binding, Competitive

المؤلفون: Zhang Z; Animal Nutrition Institute, Key Laboratory for Animal Disease-Resistance Nutrition of China, Sichuan Agricultural University, Chengdu, Sichuan, China.; Institute of Animal Husbandry and Veterinary Medicine, Meishan Vocational Technical College, Meishan, Sichuan, China.; Agricultural and Rural Bureau of Dongpo District, Meishan, China., Zhao H; Animal Nutrition Institute, Key Laboratory for Animal Disease-Resistance Nutrition of China, Sichuan Agricultural University, Chengdu, Sichuan, China., Chen X; Animal Nutrition Institute, Key Laboratory for Animal Disease-Resistance Nutrition of China, Sichuan Agricultural University, Chengdu, Sichuan, China., Tian G; Animal Nutrition Institute, Key Laboratory for Animal Disease-Resistance Nutrition of China, Sichuan Agricultural University, Chengdu, Sichuan, China., Liu G; Animal Nutrition Institute, Key Laboratory for Animal Disease-Resistance Nutrition of China, Sichuan Agricultural University, Chengdu, Sichuan, China., Cai J; Animal Nutrition Institute, Key Laboratory for Animal Disease-Resistance Nutrition of China, Sichuan Agricultural University, Chengdu, Sichuan, China., Jia G; Animal Nutrition Institute, Key Laboratory for Animal Disease-Resistance Nutrition of China, Sichuan Agricultural University, Chengdu, Sichuan, China.

المصدر: Animal science journal = Nihon chikusan Gakkaiho [Anim Sci J] 2024 Jan-Dec; Vol. 95 (1), pp. e13953.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: Australia NLM ID: 100956805 Publication Model: Print Cited Medium: Internet ISSN: 1740-0929 (Electronic) Linking ISSN: 13443941 NLM ISO Abbreviation: Anim Sci J Subsets: MEDLINE

مواضيع طبية MeSH: Jatropha* , Animal Feed* , Gastrointestinal Microbiome* , Phorbol Esters*/adverse effects , Brain-Gut Axis*/physiology, Animals ; Swine ; Diet/veterinary ; Eating ; Cytokines/metabolism ; Colon/metabolism ; Hypothalamus/metabolism ; Depression/metabolism ; Neurotransmitter Agents/metabolism

المؤلفون: Huang X; College of Pharmaceutical Science, Soochow University, Suzhou 215123, China., Huang X; Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China; Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming 650204, China., Li Q; College of Pharmaceutical Science, Soochow University, Suzhou 215123, China., Ma M; Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China., Cui Y; College of Pharmaceutical Science, Soochow University, Suzhou 215123, China., Yang L; Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China., Wang H; College of Pharmaceutical Science, Soochow University, Suzhou 215123, China., Luo R; Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China., Chen J; College of Pharmaceutical Science, Soochow University, Suzhou 215123, China., Yang J; Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China; College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China., Lin J; College of Pharmaceutical Science, Soochow University, Suzhou 215123, China., Li D; College of Pharmaceutical Science, Soochow University, Suzhou 215123, China. Electronic address: duxin.li@suda.edu.cn., Zheng Y; Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China; Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming 650204, China. Electronic address: zhengyt@mail.kiz.ac.cn., Zhang J; College of Pharmaceutical Science, Soochow University, Suzhou 215123, China. Electronic address: jianzhang@suda.edu.cn.

المصدر: Chinese journal of natural medicines [Chin J Nat Med] 2024 Apr; Vol. 22 (4), pp. 365-374.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Science Press Country of Publication: China NLM ID: 101504416 Publication Model: Print Cited Medium: Internet ISSN: 1875-5364 (Electronic) Linking ISSN: 18755364 NLM ISO Abbreviation: Chin J Nat Med Subsets: MEDLINE

مواضيع طبية MeSH: HIV-1*/drug effects , Anti-HIV Agents*/pharmacology , Anti-HIV Agents*/chemistry, Humans ; Phorbol Esters/pharmacology ; Phorbol Esters/chemistry ; Molecular Structure ; Protein Kinase C/metabolism ; Protein Kinase C/chemistry ; Structure-Activity Relationship

المؤلفون: You Y; Department of Pharmacological & Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX, USA., Mathukumalli K; Department of Pharmacological & Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX, USA., Das J; Department of Pharmacological & Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX, USA.

المصدر: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2023; Vol. 41 (21), pp. 11796-11809. Date of Electronic Publication: 2023 Jan 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE

مواضيع طبية MeSH: Molecular Dynamics Simulation* , Phorbol Esters*/chemistry , Phorbol Esters*/metabolism, Molecular Docking Simulation ; Protein Structure, Tertiary ; Ligands ; Protein Binding ; Binding Sites ; Lipids

المؤلفون: Huang X; College of Pharmaceutical Science, Soochow University, Suzhou 215123, China., Tang C; Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China., Huang X; Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China; Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan 650204, China., Yang Y; College of Pharmaceutical Science, Soochow University, Suzhou 215123, China., Li Q; College of Pharmaceutical Science, Soochow University, Suzhou 215123, China., Ma M; Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China., Zhao L; College of Pharmaceutical Science, Soochow University, Suzhou 215123, China., Yang L; Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China., Cui Y; College of Pharmaceutical Science, Soochow University, Suzhou 215123, China., Zhang Z; College of Pharmaceutical Science, Soochow University, Suzhou 215123, China. Electronic address: z_zhang@suda.edu.cn., Zheng Y; Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China; Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan 650204, China. Electronic address: zhengyt@mail.kiz.ac.cn., Zhang J; College of Pharmaceutical Science, Soochow University, Suzhou 215123, China. Electronic address: jianzhang@suda.edu.cn.

المصدر: Chinese journal of natural medicines [Chin J Nat Med] 2024 Feb; Vol. 22 (2), pp. 146-160.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Science Press Country of Publication: China NLM ID: 101504416 Publication Model: Print Cited Medium: Internet ISSN: 1875-5364 (Electronic) Linking ISSN: 18755364 NLM ISO Abbreviation: Chin J Nat Med Subsets: MEDLINE

مواضيع طبية MeSH: Anti-HIV Agents*/pharmacology , Anti-HIV Agents*/chemistry , Phorbols*/chemistry , Phorbols*/pharmacology, Molecular Docking Simulation ; Phorbol Esters/pharmacology ; HIV Reverse Transcriptase/chemistry ; HIV Reverse Transcriptase/metabolism ; Structure-Activity Relationship

المؤلفون: Tanaka N; Graduate School of Pharmaceutical Sciences, Tokushima University, Tokushima 770-8505, Japan., Takahashi S; Graduate School of Pharmaceutical Sciences, Tokushima University, Tokushima 770-8505, Japan., Yoshino Y; Graduate School of Pharmaceutical Sciences, Tokushima University, Tokushima 770-8505, Japan., Nakatani M; Graduate School of Pharmaceutical Sciences, Tokushima University, Tokushima 770-8505, Japan., Ahmed FA; Department of Botany, Faculty of Biological Sciences, Jahangirnagar University, Savar, Dhaka 1342, Bangladesh., Hossain GM; Department of Botany, Faculty of Biological Sciences, Jahangirnagar University, Savar, Dhaka 1342, Bangladesh., Chen CH; Medical Center, Duke University, Durham, North Carolina 27710, United States., Lee KH; Natural Products Laboratory, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599, United States., Kashiwada Y; Graduate School of Pharmaceutical Sciences, Tokushima University, Tokushima 770-8505, Japan.

المصدر: Journal of natural products [J Nat Prod] 2022 Nov 25; Vol. 85 (11), pp. 2687-2693. Date of Electronic Publication: 2022 Nov 15.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society of Pharmacognosy Country of Publication: United States NLM ID: 7906882 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6025 (Electronic) Linking ISSN: 01633864 NLM ISO Abbreviation: J Nat Prod Subsets: MEDLINE

مواضيع طبية MeSH: Euphorbiaceae*/chemistry , HIV*/drug effects , Phorbol Esters*/chemistry , Phorbol Esters*/isolation & purification , Phorbol Esters*/pharmacology , Anti-HIV Agents*/chemistry , Anti-HIV Agents*/isolation & purification , Anti-HIV Agents*/pharmacology, Fruit/chemistry ; Molecular Structure ; Cell Line ; Humans

المؤلفون: Neto DFM; Departamento de Fitotecnia, Universidade Federal do Ceará, CE, Brasil., Garrett R; Laboratório de Metabolômica/LADETEC, Instituto de Química, Universidade Federal do Rio de Janeiro, Brasil., Domont GB; Unidade Proteômica, Departamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, RJ, Brasil., Campos FAP; Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, CE, Brasil., Nogueira FCS; Unidade Proteômica, Departamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, RJ, Brasil.; Laboratório de Proteômica/LADETEC, Instituto de Química, Universidade Federal do Rio de Janeiro, RJ, Brasil.

المصدر: Physiologia plantarum [Physiol Plant] 2024 Mar-Apr; Vol. 176 (2), pp. e14274.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Scandinavian Society For Plant Physiology Country of Publication: Denmark NLM ID: 1256322 Publication Model: Print Cited Medium: Internet ISSN: 1399-3054 (Electronic) Linking ISSN: 00319317 NLM ISO Abbreviation: Physiol Plant Subsets: MEDLINE

مواضيع طبية MeSH: Jatropha*/genetics , Jatropha*/metabolism, Phorbol Esters/analysis ; Phorbol Esters/metabolism ; Plant Leaves/metabolism ; Seeds/genetics

المؤلفون: Houy S; Department of Neuroscience, University of Copenhagen, Copenhagen, Denmark., Martins JS; Department of Neuroscience, University of Copenhagen, Copenhagen, Denmark., Lipstein N; Department of Molecular Neurobiology, Max-Planck-Institute for Multidisciplinary Sciences, Göttingen, Germany.; Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany., Sørensen JB; Department of Neuroscience, University of Copenhagen, Copenhagen, Denmark.

المصدر: ELife [Elife] 2022 Oct 10; Vol. 11. Date of Electronic Publication: 2022 Oct 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Diglycerides* , Phorbol Esters*, Animals ; Mice ; Dense Core Vesicles ; Exocytosis ; SNARE Proteins/metabolism ; Synaptotagmins

المؤلفون: You Y; Department of Pharmacological & Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX, USA., Das J; Department of Pharmacological & Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX, USA.

المصدر: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2022; Vol. 40 (24), pp. 14160-14175. Date of Electronic Publication: 2021 Nov 15.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE

مواضيع طبية MeSH: Molecular Dynamics Simulation* , Phorbol Esters*/pharmacology , Phorbol Esters*/chemistry , Phorbol Esters*/metabolism, Ligands ; Resveratrol/pharmacology ; Lipids