نتائج البحث - "phosphatidyl inositol-3 kinase"

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
Redox Biology, Vol 11, Iss, Pp 543-553 (2017)
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Redox Biology

مصطلحات موضوعية: GSSG, glutathione disulfide, NQO1, NAD(P)H:quinone oxidoreductase 1, PrP, prionic protein, CG islands, cytosine guanine islands, Review Article, Biochemistry, UPR, unfolded protein response, HD, Huntington's disease, NRF1, lcsh:QH301-705.5, GFP, green fluorescent protein, GSH, glutathione (c-glutamyl-l-cysteinylglycine), LIR, LC3 interacting region, Brain, ALS, amyotrophic lateral sclerosis, GSK-3, glycogen synthase kinase-3, Cell biology, NRF2, nuclear factor (erythroid-derived 2)-like 2, ASK1, apoptosis-signal-regulating kinase 1, lcsh:Medicine (General), FOXO, forkhead box, β-TrCP, β-transducin repeat containing E3 ubiquitin protein ligase, NF-E2-Related Factor 2, ARE, antioxidant response element, mTOR, mammalian target of rapamycin, UBA, ubiquitin associated domain, Protein Aggregation, Pathological, 03 medical and health sciences, XBP1, X box-binding protein 1, PKC, protein kinase C, γ-GCL, γ -glutamylcysteine synthetase, Humans, α-SYN, alpha synuclein, CJD, Creutzfeldt Jakob disease, HMOX1, heme oxygenase-1, Proteasome, PI3K, phosphatidyl inositol-3 kinase, γGS, γ -glutamate cysteine synthetase, PRX, peroxiredoxin, 030104 developmental biology, Proteostasis, Oxidative stress, Unfolded protein response, TFEB, PKA, protein kinase A, 0301 basic medicine, PDI, protein disulfide isomerase, Proteome, Clinical Biochemistry, Aβ, amyloid beta, GPX, glutathione peroxidase, Endoplasmic Reticulum, CSF, cerebrospinal fluid, PD, Parkinson's disease, GST, glutathione S-transferase, TFEB, transcription factor EB, ASK1, SOD1, Cu/Zn-superoxide dismutase 1, MAPKs, mitogen-activated protein kinases, SFN, sulforaphane, Genetics, PS1, presenilin 1, lcsh:R5-920, MPTP, 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine, Neurodegenerative diseases, NRF1, nuclear factor (erythroid-derived 2)-like 1, GR, GSR, glutathione reductase, ChIP, chromatin immunoprecipitation, GCLM, glutamate-cysteine ligase modulatory subunit, IRE1, inositol-requiring kinase 1, JNK, c-Jun N-terminal kinase, AD, Alzheimer's disease, DMF, dimethyl fumarate, Proteasome Endopeptidase Complex, XBP1, TAK1, TGF-β-activated kinase 1, γGT, γ -glutamyl transpeptidase, Protein degradation, Biology, ER, endoplasmic reticulum, ROS, reactive oxygen species, UPS, ubiquitin proteasome system, APP, amyloid precursor protein, Autophagy, D3T, 1,2-dithiole-3-thione, Transcription factor, MEF, mouse embryonic fibroblasts, Htt, huntingtin, Ubiquitin, Organic Chemistry, ERO1, sulfhydryl oxidase endoplasmic oxidoreductin 1, AMPK, AMP-activated protein kinase, lcsh:Biology (General), ATF-6, activating transcription factor 6, PERK, pancreatic ER eIF2α kinase, GLT-1, glutamate transporter 1, GCLC, glutamate-cysteine ligase catalytic subunit, KEAP1, kelch-like ECH-associated protein 1

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f92176ef6df1b38f56b20a10b5b1ad8

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7

TNF receptor-associated factor 3 restrains B-cell receptor signaling in normal and malignant B cells

المؤلفون: Gail A. Bishop, Amy L. Whillock, Tiffany K. Ybarra

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Male, 0301 basic medicine, T-Lymphocytes, Syk, NIK, NF-κB-inducing kinase, Biochemistry, WB, western blot, immunology, B-cell receptor (BCR), Mice, hemic and lymphatic diseases, TRAF, TNF receptor-associated factor, Agammaglobulinaemia Tyrosine Kinase, Phosphorylation, BAFF, B-cell activating factor, Ub, ubiquitin, Mice, Knockout, TNF, tumor necrosis factor, B-Lymphocytes, biology, Chemistry, BCR, B-cell antigen receptor, breakpoint cluster region, PLCγ, phospholipase C gamma, STAT, signal transducer and activator of transcription, Btk, TNF Receptor-Associated Factor 3, inhibition mechanism, Lyn, Lck/yes novel tyrosine kinase, Female, WCL, whole-cell lysate, MZ, marginal zone, DLBCL, diffuse large B-cell lymphoma, CD79 Antigens, Research Article, TLR, Toll-like receptor, Signal Transduction, Cell signaling, LMP1, latent membrane protein 1, Syk, spleen-associated tyrosine kinase, Receptors, Antigen, B-Cell, lymphoma, lymphocyte, Btk, Bruton's tyrosine kinase, SEM, standard error of the mean, spleen tyrosine kinase (Syk), Erk, extracellular signal-regulated kinase, 03 medical and health sciences, SHP, Src homology region 2 domain-containing phosphatase, LYN, cell signaling, Animals, Syk Kinase, FO, follicular, Molecular Biology, TNF receptor-associated factor (TRAF), IκBα, NF-κB inhibitor alpha, CD40, 030102 biochemistry & molecular biology, PI3K, phosphatidyl inositol-3 kinase, T-cell receptor, ITAM, immunoreceptor tyrosine-based activation motif, Cell Biology, TNF Receptor-Associated Factor 2, MAPK, SHIP, SH2 domain-containing inositol polyphosphate 5-phosphatase, Mice, Inbred C57BL, 030104 developmental biology, TCR, T-cell receptor, biology.protein, Cancer research, BCM, B-cell medium, MAPK, mitogen-activated protein kinase, CD80

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e67cbf8c2a79407da5812e2697008d9d
https://doi.org/10.1016/j.jbc.2021.100465

8

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9

ETP-46321, a dual p110α/δ class IA phosphoinositide 3-kinase inhibitor modulates T lymphocyte activation and collagen-induced arthritis

المؤلفون: J. M. Rojo, Yenny Y. Acosta, Gabriel Criado, J. Pastor, Carmen Blanco-Aparicio, Laura Aragoneses-Fenoll, Umberto Dianzani, J. Herranz, Pilar Portolés, Gloria Ojeda, María Montes-Casado, S. Martínez

المساهمون: Ministerio de Economía y Competitividad (España), Ministerio de Ciencia y Tecnología (España), Ministerio de Sanidad, Servicios Sociales e Igualdad (España), Associazione Italiana per la Ricerca sul Cancro, Fondazione ONLUS Amici di Jean

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
Repisalud
Instituto de Salud Carlos III (ISCIII)

مصطلحات موضوعية: 0301 basic medicine, CD4-Positive T-Lymphocytes, ETP-46321, CD3 Complex, Phosphoinositide 3-kinase inhibitor, Gene Expression, Lymphocyte Activation, Biochemistry, Mice, Enzyme Inhibitors, Extracellular Signal-Regulated MAP Kinases, Phosphoinositide-3 Kinase Inhibitors, biology, A-66, Phosphatidyl inositol-3 kinase, Imidazoles, CD28, Interleukin-10, Class Ia Phosphatidylinositol 3-Kinase, medicine.anatomical_structure, Pyrazines, medicine.drug, Interleukin 2, medicine.medical_specialty, CD3, T cell, T lymphocytes, Antibodies, 03 medical and health sciences, Interferon-gamma, Immune system, CD28 Antigens, Internal medicine, medicine, Animals, Rheumatoid arthritis, Pharmacology, NFATC Transcription Factors, IC-87114, PI3K inhibitors, Arthritis, Experimental, Mice, Inbred C57BL, Protein Subunits, 030104 developmental biology, Endocrinology, ICOS, P110δ, biology.protein, Cancer research, Interleukin-2, Cytokine secretion, Lymph Nodes, T-Box Domain Proteins, Proto-Oncogene Proteins c-akt

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a7b574489ab99ea62f130de82114ca
https://hdl.handle.net/20.500.12105/10246

10

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