المؤلفون: Tang Y; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China., Qi Y; Key Laboratory of Biomedical Polymers of Ministry of Education & Department of Chemistry, Wuhan University, Wuhan 430072, China., Chen Y; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China., Wang YQ; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China., Zhang C; Key Laboratory of Biomedical Polymers of Ministry of Education & Department of Chemistry, Wuhan University, Wuhan 430072, China., Sun Y; Key Laboratory of Biomedical Polymers of Ministry of Education & Department of Chemistry, Wuhan University, Wuhan 430072, China., Huang C; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China., Zhang XZ; Key Laboratory of Biomedical Polymers of Ministry of Education & Department of Chemistry, Wuhan University, Wuhan 430072, China.

المصدر: ACS nano [ACS Nano] 2024 Aug 13; Vol. 18 (32), pp. 21077-21090. Date of Electronic Publication: 2024 Aug 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101313589 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1936-086X (Electronic) Linking ISSN: 19360851 NLM ISO Abbreviation: ACS Nano Subsets: MEDLINE

مواضيع طبية MeSH: Porphyromonas gingivalis*/drug effects , Porphyromonas gingivalis*/metabolism , Porphyromonas gingivalis*/chemistry , Periodontitis*/microbiology , Periodontitis*/drug therapy , Periodontitis*/pathology , Erythrocytes*/drug effects , Erythrocytes*/metabolism , Porphyrins*/chemistry , Porphyrins*/pharmacology, Humans ; Animals ; Reactive Oxygen Species/metabolism ; Gallium/chemistry ; Gallium/pharmacology ; Mice ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Biomimetic Materials/chemistry ; Biomimetic Materials/pharmacology

المؤلفون: Nishikawa J; Faculty of Laboratory Science, Yamaguchi University Graduate School of Medicine, Ube, Japan. Electronic address: junnis@yamaguchi-u.ac.jp., Fujii T; Faculty of Laboratory Science, Yamaguchi University Graduate School of Medicine, Ube, Japan., Fukuda S; Faculty of Laboratory Science, Yamaguchi University Graduate School of Medicine, Ube, Japan., Yoneda S; Faculty of Laboratory Science, Yamaguchi University Graduate School of Medicine, Ube, Japan., Tamura Y; Faculty of Laboratory Science, Yamaguchi University Graduate School of Medicine, Ube, Japan., Shimizu Y; Faculty of Laboratory Science, Yamaguchi University Graduate School of Medicine, Ube, Japan., Yanai A; Faculty of Laboratory Science, Yamaguchi University Graduate School of Medicine, Ube, Japan., Kobayashi Y; Faculty of Laboratory Science, Yamaguchi University Graduate School of Medicine, Ube, Japan., Harada K; Department of Oral and Maxillofacial Surgery, Yamaguchi University Graduate School of Medicin, Ube, Japan., Kawasaki K; Department of Oral and Maxillofacial Surgery, Yamaguchi University Graduate School of Medicin, Ube, Japan., Mishima K; Department of Oral and Maxillofacial Surgery, Yamaguchi University Graduate School of Medicin, Ube, Japan., Watanabe K; Center for Gene Research, Yamaguchi University, Ube, Japan., Mizukami Y; Center for Gene Research, Yamaguchi University, Ube, Japan., Yoshiyama H; Department of Microbiology, Shimane University School of Medicine, Izumo, Japan., Suehiro Y; Department of Oncology and Laboratory Medicine, Yamaguchi University Graduate School of Medicine, Ube, Japan., Yamasaki T; Department of Oncology and Laboratory Medicine, Yamaguchi University Graduate School of Medicine, Ube, Japan., Takami T; Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Ube, Japan.

المصدر: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi [J Microbiol Immunol Infect] 2024 Aug; Vol. 57 (4), pp. 533-545. Date of Electronic Publication: 2024 May 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: published by Elsevier for the Taiwan Society of Microbiology Country of Publication: England NLM ID: 100956211 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1995-9133 (Electronic) Linking ISSN: 16841182 NLM ISO Abbreviation: J Microbiol Immunol Infect Subsets: MEDLINE

مواضيع طبية MeSH: Biofilms*/drug effects , Biofilms*/radiation effects , Porphyromonas gingivalis*/drug effects , Porphyromonas gingivalis*/radiation effects , Ultraviolet Rays* , Fusobacterium nucleatum*/drug effects , Fusobacterium nucleatum*/radiation effects , Streptococcus mutans*/drug effects , Streptococcus mutans*/radiation effects , Streptococcus mutans*/physiology , Periodontitis*/microbiology, Animals ; Microscopy, Confocal ; Microscopy, Electron, Scanning ; Mice ; Microbial Viability/radiation effects ; Microbial Viability/drug effects ; Humans

المؤلفون: Betser-Cohen G; Division of Identification and Forensic Science, Police National HQ, Haim Bar-Lev 1 Road, Jerusalem, Israel. Electronic address: gila.betser@gmail.com., Mayuoni-Kirsehenbaum L; Division of Identification and Forensic Science, Police National HQ, Haim Bar-Lev 1 Road, Jerusalem, Israel., Zubeidat K; Institute of Biomedical and Oral Research, Faculty of Dental Medicine, Hebrew University, Jerusalem, Israel., Horev Y; Institute of Biomedical and Oral Research, Faculty of Dental Medicine, Hebrew University, Jerusalem, Israel., Berchoer LE; Institute of Biomedical and Oral Research, Faculty of Dental Medicine, Hebrew University, Jerusalem, Israel., Cohen A; Department of Obstetrics and Gynecology, Hadassah Medical Organization and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel., Aframian D; Department of Oral Medicine, Sedation and Imaging, Faculty of Dental Medicine, Hadassah Medical Center, Hebrew University of Jerusalem, Jerusalem, Israel., Amiel M; Division of Identification and Forensic Science, Police National HQ, Haim Bar-Lev 1 Road, Jerusalem, Israel., Hovav AH; Institute of Biomedical and Oral Research, Faculty of Dental Medicine, Hebrew University, Jerusalem, Israel. Electronic address: avihaih@ekmd.huji.ac.il.

المصدر: Forensic science international [Forensic Sci Int] 2024 Aug; Vol. 361, pp. 112112. Date of Electronic Publication: 2024 Jun 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7902034 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6283 (Electronic) Linking ISSN: 03790738 NLM ISO Abbreviation: Forensic Sci Int Subsets: MEDLINE

مواضيع طبية MeSH: Saliva*/microbiology , Real-Time Polymerase Chain Reaction* , Fusobacterium nucleatum*/isolation & purification , Fusobacterium nucleatum*/genetics , DNA, Bacterial* , Porphyromonas gingivalis*/isolation & purification , Porphyromonas gingivalis*/genetics , Streptococcus salivarius*/isolation & purification , Streptococcus salivarius*/genetics, Humans ; Microsatellite Repeats ; DNA Fingerprinting ; RNA, Ribosomal, 16S/genetics

المؤلفون: Stocke KS; Department of Oral Immunology and Infectious Diseases, University of Louisville, Louisville, Kentucky, USA., Lamont RJ; Department of Oral Immunology and Infectious Diseases, University of Louisville, Louisville, Kentucky, USA.

المصدر: Molecular oral microbiology [Mol Oral Microbiol] 2024 Aug; Vol. 39 (4), pp. 156-164. Date of Electronic Publication: 2023 May 24.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: John Wiley & Sons Country of Publication: Denmark NLM ID: 101524770 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2041-1014 (Electronic) Linking ISSN: 20411006 NLM ISO Abbreviation: Mol Oral Microbiol Subsets: MEDLINE

مواضيع طبية MeSH: Carbon*/metabolism , Porphyromonas gingivalis*/pathogenicity , Porphyromonas gingivalis*/metabolism , Folic Acid*/metabolism, Humans ; Virulence ; 4-Aminobenzoic Acid/metabolism

المؤلفون: Yamanaka R; Division of Periodontology, Department of Oral Function, Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu 803-8580, Fukuoka, Japan., Usui M; Division of Periodontology, Department of Oral Function, Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu 803-8580, Fukuoka, Japan., Kobayashi K; Division of Infections and Molecular Biology, Department of Health Promotion, Kyushu Dental University, Kitakyushu 803-8580, Fukuoka, Japan., Onizuka S; Division of Periodontology, Department of Oral Function, Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu 803-8580, Fukuoka, Japan., Kasai S; Division of Periodontology, Department of Oral Function, Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu 803-8580, Fukuoka, Japan., Sano K; Division of Periodontology, Department of Oral Function, Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu 803-8580, Fukuoka, Japan., Hironaka S; Division of Periodontology, Department of Oral Function, Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu 803-8580, Fukuoka, Japan., Yamasaki R; Division of Infections and Molecular Biology, Department of Health Promotion, Kyushu Dental University, Kitakyushu 803-8580, Fukuoka, Japan., Yoshii S; Division of Promoting Learning Design Education, Department of Physical Function, Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu 803-8580, Fukuoka, Japan., Sato T; School of Oral Health Sciences, Faculty of Dentistry, Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu 803-8580, Fukuoka, Japan., Fujii W; School of Oral Health Sciences, Faculty of Dentistry, Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu 803-8580, Fukuoka, Japan., Iwasaki M; Division of Preventive Dentistry, Department of Oral Health Science, Graduate School of Dental Medicine, Hokkaido University, Kita 13, Nishi 7, Kita-ku, Sapporo 060-8586, Hokkaido, Japan., Ariyoshi W; Division of Infections and Molecular Biology, Department of Health Promotion, Kyushu Dental University, Kitakyushu 803-8580, Fukuoka, Japan., Nakashima K; Division of Periodontology, Department of Oral Function, Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu 803-8580, Fukuoka, Japan., Nishihara T; Division of Infections and Molecular Biology, Department of Health Promotion, Kyushu Dental University, Kitakyushu 803-8580, Fukuoka, Japan.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 26; Vol. 25 (15). Date of Electronic Publication: 2024 Jul 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Porphyromonas gingivalis*/isolation & purification , Porphyromonas gingivalis*/immunology , Chromatography, Affinity*/methods , Chromatography, Affinity*/instrumentation, Humans ; Male ; Female ; Middle Aged ; Adult ; Real-Time Polymerase Chain Reaction/methods ; Periodontal Diseases/microbiology ; Periodontal Diseases/diagnosis ; Dental Plaque/microbiology ; Chronic Periodontitis/microbiology ; Chronic Periodontitis/diagnosis ; Sensitivity and Specificity

المؤلفون: Nakao R; Department of Bacteriology I, National Institute of Infectious Diseases, Tokyo, Japan., Takatsuka A; Department of Bacteriology I, National Institute of Infectious Diseases, Tokyo, Japan.; Department of Food Bioscience and Biotechnology, College of Bioresource Science, Nihon University, Kanagawa, Japan., Mandokoro K; Department of Food Bioscience and Biotechnology, College of Bioresource Science, Nihon University, Kanagawa, Japan., Narisawa N; Department of Food Bioscience and Biotechnology, College of Bioresource Science, Nihon University, Kanagawa, Japan., Ikeda T; Department of Pharmaceutical Sciences, Sojo University, Kumamoto, Japan., Takai H; Department of Periodontology, Nihon University School of Dentistry at Matsudo, Chiba, Japan., Ogata Y; Department of Periodontology, Nihon University School of Dentistry at Matsudo, Chiba, Japan.

المصدر: Microbiology spectrum [Microbiol Spectr] 2024 Jul 02; Vol. 12 (7), pp. e0342623. Date of Electronic Publication: 2024 May 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: ASM Press Country of Publication: United States NLM ID: 101634614 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2165-0497 (Electronic) Linking ISSN: 21650497 NLM ISO Abbreviation: Microbiol Spectr Subsets: MEDLINE

مواضيع طبية MeSH: Porphyromonas gingivalis*/drug effects , Porphyromonas gingivalis*/growth & development , Porphyromonas gingivalis*/physiology , Periodontitis*/microbiology , Anti-Bacterial Agents*/pharmacology , Bacterial Adhesion*/drug effects, Humans ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Catechin/pharmacology ; Fusobacterium nucleatum/drug effects ; Fusobacterium nucleatum/growth & development ; Fusobacterium nucleatum/physiology ; Adult ; Prevotella nigrescens/drug effects ; Prevotella nigrescens/physiology ; Female ; Bacteroidaceae Infections/microbiology ; Male ; Aggregatibacter actinomycetemcomitans/drug effects ; Aggregatibacter actinomycetemcomitans/growth & development ; Aggregatibacter actinomycetemcomitans/physiology

المؤلفون: Li X; Department of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China., Chen T; Department of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China., Fu Y; Department of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China., Yang B; Department of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China., Lin X; Department of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China., Hou J; Department of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. Electronic address: houjin@smu.edu.cn., Yang X; Department of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. Electronic address: yangxiaojun@i.smu.edu.cn.

المصدر: Archives of oral biology [Arch Oral Biol] 2024 Jul; Vol. 163, pp. 105965. Date of Electronic Publication: 2024 Apr 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Pergamon Press Country of Publication: England NLM ID: 0116711 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1506 (Electronic) Linking ISSN: 00039969 NLM ISO Abbreviation: Arch Oral Biol Subsets: MEDLINE

مواضيع طبية MeSH: Porphyromonas gingivalis*/pathogenicity , Porphyromonas gingivalis*/genetics , Ferroptosis*/genetics , Virulence Factors*/genetics , Human Umbilical Vein Endothelial Cells*, Humans ; Up-Regulation ; Heme Oxygenase-1/genetics ; Heme Oxygenase-1/metabolism ; Blotting, Western ; Down-Regulation ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism

المؤلفون: Śmiga M; Laboratory of Medical Biology, Faculty of Biotechnology, University of Wrocław, Wrocław, Poland., Olczak T; Laboratory of Medical Biology, Faculty of Biotechnology, University of Wrocław, Wrocław, Poland.

المصدر: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2024 Jun 13; Vol. 14, pp. 1421018. Date of Electronic Publication: 2024 Jun 13 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE

مواضيع طبية MeSH: Heme*/metabolism , Porphyromonas gingivalis*/metabolism , Porphyromonas gingivalis*/genetics , Tannerella forsythia*/metabolism , Tannerella forsythia*/genetics , Bacterial Proteins*/metabolism , Bacterial Proteins*/genetics , Porphyromonas endodontalis*/metabolism , Porphyromonas endodontalis*/genetics, Humans ; Gene Expression Regulation, Bacterial ; Protein Binding ; Iron/metabolism

المؤلفون: Ghods S; Department of Oral Immunology and Infectious Diseases, School of Dentistry, University of Louisville, Louisville, KY, United States., Muszyński A; Complex Carbohydrate Research Center, University of Georgia, Athens, GA, United States., Yang H; Department of Microbial Pathogenesis, School of Dentistry, University of Maryland, Baltimore, MD, United States., Seelan RS; Department of Oral Immunology and Infectious Diseases, School of Dentistry, University of Louisville, Louisville, KY, United States., Mohammadi A; Department of Oral Immunology and Infectious Diseases, School of Dentistry, University of Louisville, Louisville, KY, United States., Hilson JS; Complex Carbohydrate Research Center, University of Georgia, Athens, GA, United States., Keiser G; Complex Carbohydrate Research Center, University of Georgia, Athens, GA, United States., Nichols FC; Division of Periodontology, University of Connecticut School of Dental Medicine, Farmington, CT, United States., Azadi P; Complex Carbohydrate Research Center, University of Georgia, Athens, GA, United States., Ernst RK; Department of Microbial Pathogenesis, School of Dentistry, University of Maryland, Baltimore, MD, United States., Moradali F; Department of Oral Immunology and Infectious Diseases, School of Dentistry, University of Louisville, Louisville, KY, United States.

المصدر: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2024 Jun 12; Vol. 14, pp. 1418651. Date of Electronic Publication: 2024 Jun 12 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE

مواضيع طبية MeSH: Porphyromonas gingivalis*/metabolism , Porphyromonas gingivalis*/genetics , Lipopolysaccharides*/metabolism , Signal Transduction*, Virulence Factors/metabolism ; Gene Expression Regulation, Bacterial ; Energy Metabolism ; Dinucleoside Phosphates/metabolism ; Fatty Acids/metabolism ; Humans ; Bacterial Proteins/metabolism ; Bacterial Proteins/genetics

المؤلفون: Yoshida K; Department of Oral Healthcare Promotion, Tokushima University Graduate School of Biomedical Sciences, 3-18-15, Kuramoto, Tokushima, 770-8504, Japan. Electronic address: c302141001@tokushima-u.ac.jp., Yoshida K; Department of Oral Healthcare Promotion, Tokushima University Graduate School of Biomedical Sciences, 3-18-15, Kuramoto, Tokushima, 770-8504, Japan. Electronic address: kaya@tokushima-u.ac.jp., Mouri Y; Department of Oral Bioscience, Tokushima University Graduate School of Biomedical Sciences, 3-18-15, Kuramoto, Tokushima, 770-8504, Japan. Electronic address: ymouri@tokushima-u.ac.jp., Takai A; Department of Oral Healthcare Promotion, Tokushima University Graduate School of Biomedical Sciences, 3-18-15, Kuramoto, Tokushima, 770-8504, Japan. Electronic address: c302331002@tokushima-u.ac.jp., Seyama M; Department of Oral Healthcare Promotion, Tokushima University Graduate School of Biomedical Sciences, 3-18-15, Kuramoto, Tokushima, 770-8504, Japan. Electronic address: seyama.mariko@tokushima-u.ac.jp., Mekata M; Department of Oral Healthcare Promotion, Tokushima University Graduate School of Biomedical Sciences, 3-18-15, Kuramoto, Tokushima, 770-8504, Japan. Electronic address: c302231002@tokushima-u.ac.jp., Mizusawa N; Department of Oral Bioscience, Tokushima University Graduate School of Biomedical Sciences, 3-18-15, Kuramoto, Tokushima, 770-8504, Japan. Electronic address: mizusawa@tokushima-u.ac.jp., Miyoshi K; Department of Oral Bioscience, Tokushima University Graduate School of Biomedical Sciences, 3-18-15, Kuramoto, Tokushima, 770-8504, Japan. Electronic address: miyoshi@tokushima-u.ac.jp., Kudo Y; Department of Oral Bioscience, Tokushima University Graduate School of Biomedical Sciences, 3-18-15, Kuramoto, Tokushima, 770-8504, Japan. Electronic address: yasusei@tokushima-u.ac.jp., Ozaki K; Department of Oral Healthcare Promotion, Tokushima University Graduate School of Biomedical Sciences, 3-18-15, Kuramoto, Tokushima, 770-8504, Japan. Electronic address: ozaki@tokushima-u.ac.jp.

المصدر: Journal of oral biosciences [J Oral Biosci] 2024 Jun; Vol. 66 (2), pp. 365-372. Date of Electronic Publication: 2024 Apr 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101226721 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1880-3865 (Electronic) Linking ISSN: 13490079 NLM ISO Abbreviation: J Oral Biosci Subsets: MEDLINE

مواضيع طبية MeSH: Extracellular Vesicles*/metabolism , Extracellular Vesicles*/genetics , MicroRNAs*/metabolism , MicroRNAs*/genetics , Porphyromonas gingivalis*/metabolism , Porphyromonas gingivalis*/genetics, Humans ; Signal Transduction ; Bacteroidaceae Infections/microbiology ; Bacteroidaceae Infections/metabolism ; Bacteroidaceae Infections/genetics ; Lipopolysaccharides/pharmacology ; Periodontitis/microbiology ; Periodontitis/metabolism ; Periodontitis/genetics ; Up-Regulation ; Microarray Analysis