المؤلفون: Yuanjin Zhang, Yuanqing Guo, Yeye Xu, Jie Liu, Jian Lu, Xin Wang

المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 2973-2982 (2021)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: NCBI, National Center for Biotechnology Information, TALEN, transcriptional activators like effector nucleases, RNP, ribonucleoprotein, Review, Gene editing, SREBP-2, sterol regulatory element-binding protein 2, 0302 clinical medicine, AAV, adeno-associated virus, Genome editing, DDI, drug–drug interaction, CRISPR, General Pharmacology, Toxicology and Pharmaceutics, 0303 health sciences, HDR, homology directed repair, tracRNA, trans-activating crRNA, ADMET, absorption, distribution, metabolism, excretion and toxicity, HIV, human immunodeficiency virus, 030220 oncology & carcinogenesis, CRISPR-Cas9, OATP1B, organic anion transporting polypeptides 1B, Rat model, CRISPR-Cas, clustered regularly interspaced short palindromic repeats-CRISPR-associated, pre-crRNA, pre-CRISPR RNA, Computational biology, RM1-950, 03 medical and health sciences, Animal model, Pharmacokinetics, TALE, transcriptional activator-like effector, ZFN, zinc finger nucleases, DSB, double-strand break, PAM, protospacer-associated motif, Gene knockout, BSEP, bile salt export pump, 030304 developmental biology, Drug metabolism, KO, knockout, Mechanism (biology), sgRNA, single guide RNA, crRNAs, CRISPR RNAs, WT, wild-type, HBV, hepatitis B virus, T7E I, T7 endonuclease I, NHEJ, non-homologous end joining, SD, Sprague–Dawley, OTS, off-target site, DMPK, drug metabolism and pharmacokinetics, Therapeutics. Pharmacology, HPV, human papillomaviruses

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::953da916a138cd7d6b71c2e8c8f9668a
http://www.sciencedirect.com/science/article/pii/S2211383521000113

المؤلفون: Chong Zhang, Xin-Hui Xing, Xiang Zheng

المصدر: Synthetic and Systems Biotechnology
Synthetic and Systems Biotechnology, Vol 2, Iss 2, Pp 75-86 (2017)

مصطلحات موضوعية: 0301 basic medicine, CRISPR/Cas9, clustered regularly interspaced short palindromic repeats and associated protein 9, Targeted mutagenesis, Applied Microbiology and Biotechnology, TALE, transcription activator-like effector, Synthetic biology, Structural Biology, ICE, in vivo continuous evolution, CRISPR, lcsh:QH301-705.5, MAGE, multiplex automated genome engineering, media_common, HDR, homology-directed repair, Genetics, Transcription activator-like effector nuclease, dsDNA, double-stranded DNA, PAM, protospacer-adjacent motif, 3′-LTR, 3’-long terminal repeat, dCas9, catalytically dead Cas9, HIV, human immunodeficiency virus, sctetR, single chain tetR, MMEJ, microhomology-mediated end-joining, Mutations, Generator (mathematics), ZF, zinc-finger protein, tracrRNA, trans-encoded RNA, Evolution, lcsh:Biotechnology, media_common.quotation_subject, DSB, double strand break, sgRNA, single-guide RNA, DNA PolI, DNA polymerase I, Biomedical Engineering, Mutagenesis (molecular biology technique), pre-crRNA, pre-CRISPR RNA, Computational biology, Biology, Article, 03 medical and health sciences, TP, terminal protein, ORF, open reading frame, lcsh:TP248.13-248.65, TALEN, transcription activator-like effector nuclease, ssDNA, single-stranded DNA, 5-FOA, 5-fluoro-orotic acid, Trans-activating crRNA, FLASH, fast ligation-based automatable solid-phase high-throughput, DNA Pol III, DNA polymerase III, dNTP, deoxy-ribonucleoside triphosphate, ZFN, zinc-finger nuclease, TaGTEAM, targeting glycosylase to embedded arrays for mutagenesis, TP-DNAP, TP-DNA polymerase fusion, error-prone PCR, error-prone polymerase chain reaction, LIC, ligation-independent cloning, Zinc finger nuclease, non-GMO, non-genetically modified organism, NHEJ, error-prone non-homologous end-joining, 030104 developmental biology, lcsh:Biology (General), RVD, repeat variable di-residue, YOGE, yeast oligo-mediated genome engineering, Diversity (politics)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e04ffeee752a0ec5ad434bafb778e12
https://pubmed.ncbi.nlm.nih.gov/29062964

المؤلفون: Lu J; Changning Maternity and Infant Health Hospital, East China Normal University, Shanghai 200051, China.; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai 200241, China., Liu J; Changning Maternity and Infant Health Hospital, East China Normal University, Shanghai 200051, China.; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai 200241, China., Guo Y; Changning Maternity and Infant Health Hospital, East China Normal University, Shanghai 200051, China., Zhang Y; Changning Maternity and Infant Health Hospital, East China Normal University, Shanghai 200051, China., Xu Y; Changning Maternity and Infant Health Hospital, East China Normal University, Shanghai 200051, China., Wang X; Changning Maternity and Infant Health Hospital, East China Normal University, Shanghai 200051, China.; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai 200241, China.

المصدر: Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2021 Oct; Vol. 11 (10), pp. 2973-2982. Date of Electronic Publication: 2021 Jan 07.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101600560 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2211-3835 (Print) Linking ISSN: 22113835 NLM ISO Abbreviation: Acta Pharm Sin B Subsets: PubMed not MEDLINE

المؤلفون: Zheng X; Key Laboratory for Industrial Biocatalysis, Ministry of Education, Institute of Biochemical Engineering, Department of Chemical Engineering, Center for Synthetic & Systems Biology, Tsinghua University, Beijing 100084, China., Xing XH; Key Laboratory for Industrial Biocatalysis, Ministry of Education, Institute of Biochemical Engineering, Department of Chemical Engineering, Center for Synthetic & Systems Biology, Tsinghua University, Beijing 100084, China., Zhang C; Key Laboratory for Industrial Biocatalysis, Ministry of Education, Institute of Biochemical Engineering, Department of Chemical Engineering, Center for Synthetic & Systems Biology, Tsinghua University, Beijing 100084, China.

المصدر: Synthetic and systems biotechnology [Synth Syst Biotechnol] 2017 Jul 14; Vol. 2 (2), pp. 75-86. Date of Electronic Publication: 2017 Jul 14 (Print Publication: 2017).

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: KeAi Communications Co Country of Publication: China NLM ID: 101694371 Publication Model: eCollection Cited Medium: Print ISSN: 2405-805X (Print) Linking ISSN: 2405805X NLM ISO Abbreviation: Synth Syst Biotechnol Subsets: PubMed not MEDLINE