المؤلفون: Merkulova AA; Hematology and Oncology Division, Department of Medicine, Case Western Reserve University, Cleveland, Ohio., Abdalian S; Hematology and Oncology Division, Department of Medicine, Case Western Reserve University, Cleveland, Ohio; University Hospitals Cleveland Medical Center, Cleveland, Ohio., Silbak S; Hematology and Oncology Division, Department of Medicine, Case Western Reserve University, Cleveland, Ohio., Pinheiro A; Hematology and Oncology Division, Department of Medicine, Case Western Reserve University, Cleveland, Ohio., Schmaier AH; Hematology and Oncology Division, Department of Medicine, Case Western Reserve University, Cleveland, Ohio; University Hospitals Cleveland Medical Center, Cleveland, Ohio. Electronic address: Schmaier@case.edu.

المصدر: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2023 Oct; Vol. 152 (4), pp. 961-971.e7. Date of Electronic Publication: 2023 Jul 01.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Mosby Country of Publication: United States NLM ID: 1275002 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6825 (Electronic) Linking ISSN: 00916749 NLM ISO Abbreviation: J Allergy Clin Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Prekallikrein* , Factor XII*, Humans ; Endothelial Cells ; Bradykinin/pharmacology ; Kininogen, High-Molecular-Weight ; RNA, Small Interfering/genetics

المؤلفون: Bar Barroeta A; Department of Molecular Hematology, Sanquin, Amsterdam, the Netherlands; Amsterdam Cardiovascular Sciences, Pulmonary Hypertension and Thrombosis, Amsterdam, the Netherlands., Albanese P; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands; Netherlands Proteomics Centre, Utrecht, The Netherlands., Kadavá T; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands; Netherlands Proteomics Centre, Utrecht, The Netherlands., Jankevics A; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands; Netherlands Proteomics Centre, Utrecht, The Netherlands; Univ. Grenoble Alpes, CNRS, INRAE, CEA, LPCV, INSERM, UMR BioSanté U1292, Grenoble, France., Marquart JA; Department of Molecular Hematology, Sanquin, Amsterdam, the Netherlands., Meijers JCM; Department of Molecular Hematology, Sanquin, Amsterdam, the Netherlands; Amsterdam Cardiovascular Sciences, Pulmonary Hypertension and Thrombosis, Amsterdam, the Netherlands; Department of Experimental Vascular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: j.c.meijers@amsterdamumc.nl., Scheltema RA; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands; Netherlands Proteomics Centre, Utrecht, The Netherlands; Department of Biochemistry, Cell & Systems Biology, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, UK. Electronic address: r.a.scheltema@uu.nl.

المصدر: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2024 May; Vol. 22 (5), pp. 1336-1346. Date of Electronic Publication: 2024 Jan 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 101170508 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7836 (Electronic) Linking ISSN: 15387836 NLM ISO Abbreviation: J Thromb Haemost Subsets: MEDLINE

مواضيع طبية MeSH: Thrombin*/metabolism , Thrombin*/chemistry , Factor XI*/metabolism , Factor XI*/chemistry , Molecular Dynamics Simulation* , Protein Binding*, Humans ; Binding Sites ; Protein Multimerization ; Mutation ; Protein Conformation ; Blood Coagulation ; Prekallikrein/metabolism ; Prekallikrein/chemistry ; Protein Subunits/metabolism ; Enzyme Activation ; Factor XIa/metabolism ; Factor XIa/chemistry

المؤلفون: Boullard NG; Jackson Hinds Comprehensive Health Center, Jackson, MS 39216, USA., Paris JJ; Division of Pharmacology, School of Pharmacy, University of Mississippi, Oxford, MS 38677, USA., Shariat-Madar Z; Division of Pharmacology, School of Pharmacy, University of Mississippi, Oxford, MS 38677, USA., Mahdi F; Division of Pharmacology, School of Pharmacy, University of Mississippi, Oxford, MS 38677, USA.

المصدر: Molecules (Basel, Switzerland) [Molecules] 2024 May 09; Vol. 29 (10). Date of Electronic Publication: 2024 May 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

مواضيع طبية MeSH: Cellular Senescence* , Endothelial Cells*/metabolism , Biomarkers*/metabolism , Carboxypeptidases*/metabolism , Carboxypeptidases*/genetics, Humans ; Prekallikrein/metabolism ; Prekallikrein/genetics ; Bradykinin/pharmacology ; Bradykinin/metabolism ; Pulmonary Artery/metabolism ; Pulmonary Artery/cytology ; Cells, Cultured ; Kininogen, High-Molecular-Weight/metabolism ; Signal Transduction ; Nitric Oxide Synthase Type III/metabolism ; Nitric Oxide Synthase Type III/genetics ; Kallikreins/metabolism ; Kallikreins/genetics

المؤلفون: Shu Y; Evidence-based Medicine and Clinical Center, The First People's Hospital of Huaihua, Huaihua, 418000, P.R. China., Zhao X; Department of General Practice, The First People's Hospital of Huaihua, Huaihua, 418000, P.R. China., Yang C; Department of Laboratory Medicine, The First People's Hospital of Huaihua, Huaihua, 418000, P.R. China., Yan Y; School of Public Health and Laboratory Medicine, Hunan University of Medicine, Huaihua, 418000, P.R. China., Zheng Y; College of Biology and Environmental Sciences, Jishou University, Jishou, 416000, P.R. China., Wang X; College of Biology and Environmental Sciences, Jishou University, Jishou, 416000, P.R. China., Qiu C; Evidence-based Medicine and Clinical Center, The First People's Hospital of Huaihua, Huaihua, 418000, P.R. China. qiuchengfeng0721@163.com.; Department of Clinical Pharmacy, The First People's Hospital of Huaihua, Huaihua, 418000, P.R. China. qiuchengfeng0721@163.com.; School of Basic Medical Sciences, University of South China, Hengyang, 421000, P.R. China. qiuchengfeng0721@163.com.

المصدر: Lipids in health and disease [Lipids Health Dis] 2023 Jun 23; Vol. 22 (1), pp. 79. Date of Electronic Publication: 2023 Jun 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101147696 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-511X (Electronic) Linking ISSN: 1476511X NLM ISO Abbreviation: Lipids Health Dis Subsets: MEDLINE

مواضيع طبية MeSH: East Asian People* , Hyperlipidemias*/blood , Prekallikrein*/analysis, Humans ; Cholesterol, HDL ; Cross-Sectional Studies ; Hypercholesterolemia/blood ; Hypertriglyceridemia/blood ; Triglycerides ; Infant ; Child, Preschool ; Child ; Adolescent ; Young Adult ; Adult ; Middle Aged ; Aged ; Aged, 80 and over

المؤلفون: Litvak M; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Shamanaev A; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Zalawadiya S; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Matafonov A; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Kobrin A; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Feener EP; KalVista Pharmaceuticals, Inc., Cambridge, Massachusetts, USA., Wallisch M; Aronora, Inc., Portland, Oregon, USA; Department of Biomedical Engineering, Oregon Health & Science University, Oregon, USA., Tucker EI; Aronora, Inc., Portland, Oregon, USA; Department of Biomedical Engineering, Oregon Health & Science University, Oregon, USA., McCarty OJT; Department of Biomedical Engineering, Oregon Health & Science University, Oregon, USA., Gailani D; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA. Electronic address: dave.gailani@vumc.org.

المصدر: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2023 May; Vol. 21 (5), pp. 1200-1213. Date of Electronic Publication: 2022 Dec 22.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 101170508 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7836 (Electronic) Linking ISSN: 15387836 NLM ISO Abbreviation: J Thromb Haemost Subsets: MEDLINE

مواضيع طبية MeSH: Kaolin* , Prekallikrein*/metabolism, Humans ; Factor XI/metabolism ; Factor XII/metabolism ; Titanium

المؤلفون: Chen ZL; The Rockefeller University, Patricia and John Rosenwald Laboratory of Neurobiology and Genetics, New York, NY., Singh PK; The Rockefeller University, Patricia and John Rosenwald Laboratory of Neurobiology and Genetics, New York, NY., Horn K; The Rockefeller University, Patricia and John Rosenwald Laboratory of Neurobiology and Genetics, New York, NY., Calvano MR; The Rockefeller University, Patricia and John Rosenwald Laboratory of Neurobiology and Genetics, New York, NY., Kaneki S; The Rockefeller University, Patricia and John Rosenwald Laboratory of Neurobiology and Genetics, New York, NY., McCrae KR; Taussig Cancer Institute and Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, OH., Strickland S; The Rockefeller University, Patricia and John Rosenwald Laboratory of Neurobiology and Genetics, New York, NY., Norris EH; The Rockefeller University, Patricia and John Rosenwald Laboratory of Neurobiology and Genetics, New York, NY.

المصدر: Blood advances [Blood Adv] 2023 Apr 11; Vol. 7 (7), pp. 1156-1167.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE

مواضيع طبية MeSH: Prekallikrein*/chemistry , Prekallikrein*/metabolism , Thrombosis*, Humans ; Animals ; Mice ; Factor XI/metabolism ; Bradykinin/pharmacology ; Bradykinin/chemistry ; Kininogen, High-Molecular-Weight/chemistry ; Kininogen, High-Molecular-Weight/metabolism

المؤلفون: Adenaeuer A; Institute for Clinical Chemistry and Laboratory Medicine, University Medical Center Mainz, Johannes Gutenberg University, Mainz, Germany; Center for Thrombosis and Hemostasis, University Medical Center Mainz, Johannes Gutenberg University, Mainz, Germany., Barco S; Center for Thrombosis and Hemostasis, University Medical Center Mainz, Johannes Gutenberg University, Mainz, Germany; Department of Angiology, University Hospital Zurich, Zurich, Switzerland., Trinchero A; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland., Krutmann S; Center for Thrombosis and Hemostasis, University Medical Center Mainz, Johannes Gutenberg University, Mainz, Germany., Nazir HF; Child Health Department, Sultan Qaboos University Hospital, Muscat, Oman; Department of Pediatrics, Alexandria Faculty of Medicine, Alexandria, Egypt., Ambaglio C; Department of Immunohematology and Transfusion Medicine, Papa Giovanni XXIII Hospital, Bergamo, Italy., Rocco V; Dipartimento di Medicina di Laboratorio, Azienda Ospedaliera G. Rummo, Benevento, Italy., Pancione Y; Dipartimento di Medicina di Laboratorio, Azienda Ospedaliera G. Rummo, Benevento, Italy., Tomao L; Unit of Clinical Pathology, Bambino Gesù Children's Hospital IRCCS, Rome, Italy; Department of Pediatric Hematology-Oncology, Bambino Gesù Children's Hospital IRCCS, Rome, Italy., Ruiz-Sáez A; Centro Nacional de Hemofilia, Banco Municipal de Sangre del Distrito Capital, Caracas, Venezuela., Echenagucia M; Centro Nacional de Hemofilia, Banco Municipal de Sangre del Distrito Capital, Caracas, Venezuela., Alesci S; IMD Blood Coagulation Centre, Frankfurt/Bad Homburg, Germany., Sollfrank S; Institute for Clinical Chemistry and Laboratory Medicine, University Medical Center Mainz, Johannes Gutenberg University, Mainz, Germany; Center for Thrombosis and Hemostasis, University Medical Center Mainz, Johannes Gutenberg University, Mainz, Germany., Ezigbo ED; Institute for Clinical Chemistry and Laboratory Medicine, University Medical Center Mainz, Johannes Gutenberg University, Mainz, Germany; Department of Medical Laboratory Science, University of Nigeria, Nsukka, Nigeria., Häuser F; Institute for Clinical Chemistry and Laboratory Medicine, University Medical Center Mainz, Johannes Gutenberg University, Mainz, Germany., Lackner KJ; Institute for Clinical Chemistry and Laboratory Medicine, University Medical Center Mainz, Johannes Gutenberg University, Mainz, Germany., Lämmle B; Center for Thrombosis and Hemostasis, University Medical Center Mainz, Johannes Gutenberg University, Mainz, Germany; Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Rossmann H; Institute for Clinical Chemistry and Laboratory Medicine, University Medical Center Mainz, Johannes Gutenberg University, Mainz, Germany. Electronic address: heidi.rossmann@unimedizin-mainz.de.

المصدر: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2023 Feb; Vol. 21 (2), pp. 237-254. Date of Electronic Publication: 2022 Dec 22.

نوع المنشور: Systematic Review; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 101170508 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7836 (Electronic) Linking ISSN: 15387836 NLM ISO Abbreviation: J Thromb Haemost Subsets: MEDLINE

مواضيع طبية MeSH: Kininogen, High-Molecular-Weight*/genetics , Kininogen, High-Molecular-Weight*/metabolism , Prekallikrein*/genetics , Prekallikrein*/metabolism, Prevalence ; Blood Coagulation Factors

SCR Disease Name: Flaujeac factor deficiency

المؤلفون: Xu LC; Department of Surgery, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA., Siedlecki CA; Department of Surgery, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.; Department of Bioengineering, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.

المصدر: Journal of biomedical materials research. Part A [J Biomed Mater Res A] 2024 Aug; Vol. 112 (8), pp. 1213-1223. Date of Electronic Publication: 2023 Sep 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101234237 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4965 (Electronic) Linking ISSN: 15493296 NLM ISO Abbreviation: J Biomed Mater Res A Subsets: MEDLINE

مواضيع طبية MeSH: Wettability*, Humans ; Hydrophobic and Hydrophilic Interactions ; Factor XIIa/metabolism ; Factor XIIa/antagonists & inhibitors ; Prekallikrein/metabolism ; Glass/chemistry ; Blood Coagulation/drug effects ; Factor XII/metabolism ; Factor XII/antagonists & inhibitors ; Silanes/chemistry ; Surface Properties

المؤلفون: Riedl MA; Division of Allergy and Immunology, University of California, San Diego, La Jolla, Calif. Electronic address: mriedl@health.ucsd.edu., Bordone L; Ionis Pharmaceuticals, Carlsbad, Calif., Revenko A; Ionis Pharmaceuticals, Carlsbad, Calif., Newman KB; Ionis Pharmaceuticals, Carlsbad, Calif., Cohn DM; Department of Vascular Medicine, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.

المصدر: The journal of allergy and clinical immunology. In practice [J Allergy Clin Immunol Pract] 2024 Apr; Vol. 12 (4), pp. 911-918. Date of Electronic Publication: 2023 Dec 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101597220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2201 (Electronic) NLM ISO Abbreviation: J Allergy Clin Immunol Pract Subsets: MEDLINE

مواضيع طبية MeSH: Angioedemas, Hereditary*/genetics , Angioedemas, Hereditary*/prevention & control, Humans ; Bradykinin/therapeutic use ; Bradykinin/metabolism ; Complement C1 Inhibitor Protein/therapeutic use ; Liver/metabolism ; Prekallikrein

المؤلفون: Petersen RS; Department of Vascular Medicine, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands., Bordone L; Ionis Pharmaceuticals, Inc., Carlsbad, California, USA., Riedl MA; University of California San Diego, La Jolla, California, USA., Tachdjian R; Department of Pediatrics, University of California, Los Angeles, California, USA.; Providence Saint John's Health Center, Santa Monica, California, USA., Craig TJ; Department of Medicine, Pediatrics, and Biomedical Sciences, Pennsylvania State University, Hershey, Pennsylvania, USA.; Vinmec International Hospital, Times City, Hanoi, Vietnam., Lumry WR; Allergy and Asthma Research Associates Research Center, Dallas, Texas, USA., Manning ME; Medical Research of Arizona, Scottsdale, Arizona, USA., Bernstein JA; Department of Internal Medicine, University of Cincinnati College of Medicine, and Bernstein Clinical Research Center, Cincinnati, Ohio, USA., Raasch J; Midwest Immunology Clinic, Plymouth, Minnesota, USA., Zuraw BL; Division of Rheumatology, Allergy, and Immunology, Department of Medicine, University of California San Diego, La Jolla, California, USA., Deng Y; Ionis Pharmaceuticals, Inc., Carlsbad, California, USA., Newman KB; Ionis Pharmaceuticals, Inc., Carlsbad, California, USA., Alexander VJ; Ionis Pharmaceuticals, Inc., Carlsbad, California, USA., Lui C; Ionis Pharmaceuticals, Inc., Carlsbad, California, USA., Schneider E; Ionis Pharmaceuticals, Inc., Carlsbad, California, USA., Cohn DM; Department of Vascular Medicine, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.

المصدر: Allergy [Allergy] 2024 Mar; Vol. 79 (3), pp. 724-734. Date of Electronic Publication: 2023 Nov 27.

نوع المنشور: Clinical Trial, Phase II; Randomized Controlled Trial; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: Denmark NLM ID: 7804028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1398-9995 (Electronic) Linking ISSN: 01054538 NLM ISO Abbreviation: Allergy Subsets: MEDLINE

مواضيع طبية MeSH: Angioedemas, Hereditary*/drug therapy , Oligonucleotides*, Humans ; Prekallikrein ; Quality of Life ; Treatment Outcome ; Complement C1 Inhibitor Protein/therapeutic use