المؤلفون: Louise Selby, Sejal Saglani

المصدر: Current Opinion in Allergy & Clinical Immunology. 19:132-140

مصطلحات موضوعية: medicine.medical_specialty, Allergy, MONOCLONAL-ANTIBODY, AIRWAY INFLAMMATION, Immunology, Omalizumab, Disease, Severity of Illness Index, Medication Adherence, severe therapy resistant asthma, DOUBLE-BLIND, OMALIZUMAB, problematic severe asthma, Maintenance therapy, Adrenal Cortex Hormones, immunomodulatory drugs, Severity of illness, medicine, Humans, Immunology and Allergy, Anti-Asthmatic Agents, adherence, Precision Medicine, Child, Intensive care medicine, Asthma, Science & Technology, RECEPTOR, business.industry, BENRALIZUMAB, EFFICACY, medicine.disease, Precision medicine, LIFE, Clinical trial, Phenotype, 1107 Immunology, SAFETY, Disease Progression, business, Life Sciences & Biomedicine, Mepolizumab, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec1211a6a2a2a033467d2c98b06e5c3
https://doi.org/10.1097/aci.0000000000000521

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المؤلفون: Valentina Fainardi, Aldara Martin Alonso, Sejal Saglani

المصدر: Expert Review of Respiratory Medicine. 11:867-874

مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, Severe asthma, Therapy resistant, medicine.medical_specialty, Pediatrics, AIRWAY INFLAMMATION, Respiratory System, CHILDHOOD, INNATE LYMPHOID-CELLS, Asthma management, CORTICOSTEROID RESPONSE, 03 medical and health sciences, 0302 clinical medicine, children, medicine, Risk of mortality, Humans, Immunology and Allergy, PROBLEMATIC SEVERE ASTHMA, Child, Intensive care medicine, SEVERE EOSINOPHILIC ASTHMA, Asthma, mechanisms, Childhood asthma, Science & Technology, PEDIATRIC-PATIENTS, business.industry, phenotypes, Public Health, Environmental and Occupational Health, BLOOD EOSINOPHILS, medicine.disease, Phenotype, MICE, 030104 developmental biology, 1117 Public Health And Health Services, 030228 respiratory system, Poor control, DISEASE SEVERITY, pathology, business, Life Sciences & Biomedicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55331c48966267f7cd7976d111223e63
https://doi.org/10.1080/17476348.2017.1368391

المؤلفون: Jordan A. Ramilowski, Carsten O. Daub, Erik Melén, Jon R Konradsen, Andrew T. Kwon, Björn Nordlund, Cilla Söderhäll, Michiel J. L. de Hoon, Yoshihide Hayashizaki, Gunilla Hedlin, Helena Persson, Gilad Silberberg, Juha Kere, Christina Orsmark-Pietras

المساهمون: Research Programs Unit, Juha Kere / Principal Investigator, Research Programme for Molecular Neurology

المصدر: Journal of Allergy and Clinical Immunology. 136(3):638-648

مصطلحات موضوعية: Male, Adolescent, Immunology, Drug Resistance, LOCI, CHILDREN, PHENOTYPES, Genome-wide association study, Biology, Bioinformatics, Severity of Illness Index, DIFFERENTIAL EXPRESSION, Transcriptome, Receptors, Glucocorticoid, childhood asthma, Gene expression, Humans, peripheral blood leukocytes, Immunology and Allergy, RNA, Messenger, PROBLEMATIC SEVERE ASTHMA, long noncoding RNA, GENOME-WIDE ASSOCIATION, Child, Glucocorticoids, Gene, Transcription factor, SETS, Therapy-resistant asthma, Gene Expression Profiling, JNK Mitogen-Activated Protein Kinases, Nuclear Receptor Subfamily 1, Group F, Member 1, Asthma, Long non-coding RNA, Cap analysis gene expression, 3. Good health, Gene expression profiling, EXACERBATIONS, Case-Control Studies, Child, Preschool, CELLS, Female, 3111 Biomedicine, transcriptome, Genome-Wide Association Study

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea34c5fcb1c14cb7d860a9fa345d200c

المؤلفون: Grigg, J, Rusconi, F, van Aalderen, W, Rutjes, Nwp, Carlsen, Kcl, Coleman, C, Chalmers, Jd, Cunningham, S, Fernandes, Rm, Fleming, Lj, Frankemölle, B, Gappa, M, Karadag, B, Liu, Nm, Midulla, F, Pijnenburg, MARIA WILHELMINA HELENA

المساهمون: Pediatrics, Paediatric Pulmonology, Graduate School, APH - Personalized Medicine, AII - Inflammatory diseases, AII - Amsterdam institute for Infection and Immunity

المصدر: European Respiratory Journal, 52(4):1801665. European Respiratory Society
European respiratory journal, 52(4):1801665. European Respiratory Society

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, medicine.medical_specialty, Adolescent, Severe asthma, MEDLINE, macromolecular substances, 03 medical and health sciences, 0302 clinical medicine, Quality of life (healthcare), Professional-Family Relations, immune system diseases, medicine, Humans, Multicenter Studies as Topic, 030212 general & internal medicine, Patient participation, Child, Intensive care medicine, Asthma, Biological Products, business.industry, musculoskeletal, neural, and ocular physiology, medicine.disease, Therapeutic trial, respiratory tract diseases, Europe, Clinical research, Paediatric asthma, nervous system, 030228 respiratory system, Quality of Life, Patient Compliance, Patient Participation, problematic severe asthma, childhood, definition, features, burden, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d1d79ec93de8145a1537530aef792d
https://pure.eur.nl/en/publications/b079c496-8de9-48ab-be01-8768fcf98f54

المصدر: BMJ Open. 7(12)

مصطلحات موضوعية: DOUBLE-BLIND, SUBLINGUAL IMMUNOTHERAPY, PEDIATRIC-PATIENTS, ALLERGEN-SPECIFIC IMMUNOTHERAPY, HYPOSENSITIZATION THERAPY, HOUSE-DUST MITE, DERMATOPHAGOIDES-PTERONYSSINUS, RESPIRATORY ALLERGY, PROBLEMATIC SEVERE ASTHMA, RANDOMIZED CONTROLLED-TRIAL

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dris___01423::b7a8852107299bd2ffc64c4eaa594124
https://research.rug.nl/en/publications/d01f2e9e-e4e6-4822-9c6c-cb34f599590e

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المؤلفون: Mandal, A, Shahi, PK

مصطلحات موضوعية: Severe therapy-resistant asthma, Problematic severe asthma, Allergic rhinitis, respiratory tract diseases, Metered dose inhaler

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b52a177d098505eaea2dea0074708e

المؤلفون: Sejal Saglani, Clare M. Lloyd

مصطلحات موضوعية: 0301 basic medicine, Disease, 0302 clinical medicine, Risk Factors, T-Lymphocyte Subsets, Immunology and Allergy, PROBLEMATIC SEVERE ASTHMA, Child, Innate lymphoid cell, Age Factors, TOBACCO-SMOKE EXPOSURE, Early life, HUMAN CORD-BLOOD, 1ST 3 MONTHS, Phenotype, 1107 Immunology, Host-Pathogen Interactions, Disease Susceptibility, medicine.symptom, Life Sciences & Biomedicine, Adult, Immunology, INNATE LYMPHOID-CELLS, Inflammation, Environment, Biology, 03 medical and health sciences, Immune system, Immunity, Wheeze, Hypersensitivity, medicine, Animals, Humans, Asthma, TYPE-2 IMMUNITY, Science & Technology, wheezing, TOLL-LIKE RECEPTOR-4, CHILDHOOD ASTHMA, asthma, medicine.disease, Immunity, Innate, 030104 developmental biology, 030228 respiratory system, immune development, inflammation, T-CELLS, PEDIATRIC SEVERE ASTHMA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1b6d5d4fe76c957be8913b837b9b6f
http://hdl.handle.net/10044/1/51366

المؤلفون: Bush, A, Fleming, L, Saglani, S

المساهمون: National Institute for Health Research, Asthma UK, European Respiratory Society

مصطلحات موضوعية: obesity, Science & Technology, FUNGAL SENSITIZATION, exercise-induced laryngeal obstruction, UPPER AIRWAY, Respiratory System, THERAPY-RESISTANT ASTHMA, 11 Medical And Health Sciences, RANDOMIZED CONTROLLED-TRIAL, respiratory tract diseases, LUNG-FUNCTION, SEVERE CHILDHOOD ASTHMA, immune system diseases, VOCAL CORD DYSFUNCTION, INDUCED LARYNGEAL OBSTRUCTION, innate lymphoid cell, PEDIATRIC SEVERE ASTHMA, adherence, PROBLEMATIC SEVERE ASTHMA, Life Sciences & Biomedicine, steroid resistance

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______1032::fc23f346c47eace1bfe4fcf24db44837
http://hdl.handle.net/10044/1/50679