المؤلفون: Hussein Ghazale, EunJee Park, Lakshmy Vasan, James Mester, Fermisk Saleh, Andrea Trevisiol, Dawn Zinyk, Vorapin Chinchalongporn, Mingzhe Liu, Taylor Fleming, Oleksandr Prokopchuk, Natalia Klenin, Deborah Kurrasch, Maryam Faiz, Bojana Stefanovic, JoAnne McLaurin, Carol Schuurmans

المصدر: Frontiers in Neuroscience, Vol 16 (2022)

مصطلحات موضوعية: proneural bHLH transcription factors, phospho-site mutations, neuronal reprogramming, cerebral cortex, astrocytes, induced neuron, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnins.2022.917071/full; https://doaj.org/toc/1662-453X

URL الوصول: https://doaj.org/article/0eb03c295a474e0c9abfd4326919866b

المؤلفون: Diogo S. Soares, Catarina C.F. Homem, Diogo S. Castro

المصدر: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

مصطلحات موضوعية: Ascl1, asense, proneural bHLH transcription factors, neurogenesis, neural/stem progenitor cells, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2022.838431/full; https://doaj.org/toc/2296-634X

URL الوصول: https://doaj.org/article/8f84fd949a3a4678926eb4588b7c5c0c

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المؤلفون: Ondine Cleaver

المصدر: Developmental Cell

مصطلحات موضوعية: 0301 basic medicine, endocrine system, proneural bHLH transcription factors, Cell, Nerve Tissue Proteins, neurogenin3, insulinoma, digestive system, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Islets of Langerhans, Mice, pancreatic development, Cyclin-dependent kinase, Insulin-Secreting Cells, pancreatic organoids, medicine, Animals, Humans, Progenitor cell, Molecular Biology, Transcription factor, book, Regulation of gene expression, biology, diabetes, Developmental cell, Gene Expression Regulation, Developmental, Cell Differentiation, Cell Biology, Cell cycle, β cells, Cell biology, endocrine differentiation, 030104 developmental biology, medicine.anatomical_structure, biology.protein, Phosphorylation, book.journal, Developmental Biology, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b011ab77d0d78d6252bcb83ba6fa3207
https://pubmed.ncbi.nlm.nih.gov/28457793

المؤلفون: Azzarelli, R., Hurley, C., Sznurkowska, M., Rulands, S., Hardwick, L., Gamper, I., Ali, F., McCracken, L., Hindley, C., McDuff, F., Nestorowa, S., Kemp, R., Jones, K., Goettgens, B., Huch, M., Evan, G., Simons, B., Winton, D., Philpott, A.

المساهمون: Rulands, Steffen [0000-0001-6398-1553], Gottgens, Berthold [0000-0001-6302-5705], Huch Ortega, Meritxell [0000-0002-1545-5265], Evan, Gerard [0000-0003-0412-1216], Simons, Benjamin [0000-0002-3875-7071], Winton, Douglas [0000-0001-6067-7927], Philpott, Anna [0000-0003-3789-2463], Apollo - University of Cambridge Repository

المصدر: Developmental Cell

مصطلحات موضوعية: Homeodomain Proteins, endocrine system, proneural bHLH transcription factors, diabetes, Cell Differentiation, Nerve Tissue Proteins, insulinoma, neurogenin3, β cells, digestive system, Cyclin-Dependent Kinases, Living matter, Islets of Langerhans, Mice, endocrine differentiation, pancreatic development, pancreatic organoids, Animals, Basic Helix-Loop-Helix Transcription Factors, Humans, Insulin-Secreting Cells, Pancreas, Phosphorylation, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ae452267081673fa11edb3c96ce66d9b
https://www.repository.cam.ac.uk/handle/1810/265388

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المؤلفون: Azzarelli, R, Hurley, C, Sznurkowska, MK, Rulands, S, Hardwick, L, Gamper, I, Ali, F, McCracken, L, Hindley, C, McDuff, F, Nestorowa, S, Kemp, R, Jones, K, Göttgens, B, Huch, M, Evan, G, Simons, BD, Winton, D, Philpott, A

مصطلحات موضوعية: endocrine system, endocrine differentiation, proneural bHLH transcription factors, pancreatic development, diabetes, pancreatic organoids, insulinoma, neurogenin3, β cells, digestive system, 3. Good health

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d091119c31aa37814df92a7b9ea87f2d

المؤلفون: Azzarelli R; Department of Oncology, University of Cambridge, Hutchison/MRC Research Centre, Hills Road, Cambridge CB2 0XZ, UK; Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK., Hurley C; Department of Oncology, University of Cambridge, Hutchison/MRC Research Centre, Hills Road, Cambridge CB2 0XZ, UK; Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK., Sznurkowska MK; Department of Oncology, University of Cambridge, Hutchison/MRC Research Centre, Hills Road, Cambridge CB2 0XZ, UK; Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK., Rulands S; Max Planck Institute for the Physics of Complex Systems, Nöthnitzer Straße 38, 01187 Dresden, Germany; Center for Systems Biology Dresden, Pfotenhauer Straße 108, 01307 Dresden, Germany., Hardwick L; Department of Oncology, University of Cambridge, Hutchison/MRC Research Centre, Hills Road, Cambridge CB2 0XZ, UK; Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK., Gamper I; Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, UK., Ali F; Department of Oncology, University of Cambridge, Hutchison/MRC Research Centre, Hills Road, Cambridge CB2 0XZ, UK; Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK., McCracken L; Department of Oncology, University of Cambridge, Hutchison/MRC Research Centre, Hills Road, Cambridge CB2 0XZ, UK; Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK., Hindley C; The Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge CB2 1QN, UK; Cavendish Laboratory, Department of Physics, University of Cambridge, Cambridge CB3 0HE, UK., McDuff F; Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, UK., Nestorowa S; Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK; Department of Haematology, Cambridge Institute for Medical Research, Hills Road, Cambridge CB2 0XY, UK., Kemp R; Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK., Jones K; Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK., Göttgens B; Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK; Department of Haematology, Cambridge Institute for Medical Research, Hills Road, Cambridge CB2 0XY, UK., Huch M; The Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge CB2 1QN, UK., Evan G; Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, UK., Simons BD; Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK; The Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge CB2 1QN, UK; Cavendish Laboratory, Department of Physics, University of Cambridge, Cambridge CB3 0HE, UK., Winton D; Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK., Philpott A; Department of Oncology, University of Cambridge, Hutchison/MRC Research Centre, Hills Road, Cambridge CB2 0XZ, UK; Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK. Electronic address: ap113@cam.ac.uk.

المصدر: Developmental cell [Dev Cell] 2017 May 08; Vol. 41 (3), pp. 274-286.e5. Date of Electronic Publication: 2017 Apr 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101120028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1551 (Electronic) Linking ISSN: 15345807 NLM ISO Abbreviation: Dev Cell Subsets: MEDLINE

مواضيع طبية MeSH: Basic Helix-Loop-Helix Transcription Factors/*metabolism , Cell Differentiation/*physiology , Insulin-Secreting Cells/*metabolism , Islets of Langerhans/*cytology , Nerve Tissue Proteins/*metabolism, Animals ; Cyclin-Dependent Kinases/metabolism ; Homeodomain Proteins/metabolism ; Humans ; Mice ; Pancreas/metabolism ; Phosphorylation ; Signal Transduction/physiology