-
1دورية أكاديمية
المؤلفون: Yang, Zhen, Misner, Bobbye, Ji, Haitao, Poulos, Thomas L, Silverman, Richard B, Meyskens, Frank L, Yang, Sun
المصدر: Antioxidants & redox signaling. 19(5)
مصطلحات موضوعية: Animals, Arginine: pharmacology, Blotting, Western, Cell Line, Cells, Cultured, Enzyme Inhibitors: therapeutic use, Humans, Male, Melanocytes: drug effects, enzymology, radiation effects, Melanoma: drug therapy, enzymology, Mice, Mice, Nude, Nitric Oxide: metabolism, Nitric Oxide Synthase Type I: antagonists & inhibitors, genetics, metabolism, RNA, Small Interfering, Tumor Cells, Cultured, Ultraviolet Rays, arginine, interstitial collagenase, nitric oxide, nitric oxide synthase inhibitor, protein bcl 2, transcription factor JunD, antineoplastic activity, article, cancer growth, human, human cell, in vitro study, melanocyte, melanoma, melanoma cell, metastasis, priority journal, tumor invasion, Animals, Arginine, Blotting, Western, Cell Line, Cells, Cultured, Enzyme Inhibitors, Humans, Male, Melanocytes, Melanoma, Mice, Mice, Nude, Nitric Oxide, Nitric Oxide Synthase Type I, RNA, Small Interfering, Tumor Cells, Cultured, Ultraviolet Rays
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/7hd8672z
-
2دورية أكاديمية
المؤلفون: Yang, Zhen, Yang, Sun, Misner, Bobbye J, Chiu, Rita, Liu, Feng, Meyskens, Frank L, Jr
المصدر: Molecular cancer therapeutics. 7(12)
مصطلحات موضوعية: Antineoplastic Agents, Phytogenic: metabolism, pharmacology, Cell Line, Tumor, Cell Proliferation, DNA-(Apurinic or Apyrimidinic Site) Lyase: metabolism, physiology, Disease Progression, Feedback, Physiological, Gene Expression Regulation, Enzymologic, Gene Expression Regulation, Neoplastic, Humans, Melanoma: metabolism, pathology, Models, Biological, Neoplasm Metastasis, Nitric Oxide: metabolism, Stilbenes: pharmacology, Transcription Factor AP-1: physiology, apurinic acid, deoxyribonuclease I, diethylenetriamine, inducible nitric oxide synthase, interstitial collagenase, nitric oxide, protein bcl 2, redox effector factor 1, resveratrol, small interfering RNA, transcription factor AP 1, transcription factor JunD, apyrimidinic site, article, cancer growth, cell proliferation, cell stimulation, controlled study, enzyme inhibition, feedback system, human, human cell, melanoma, metastasis, priority journal, reverse transcription polymerase chain reaction, Western blotting, Antineoplastic Agents, Phytogenic, Cell Line, Tumor, Cell Proliferation, Disease Progression, DNA-(Apurinic or Apyrimidinic Site) Lyase, Feedback, Biochemical, Gene Expression Regulation, Enzymologic, Gene Expression Regulation, Neoplastic, Humans, Melanoma, Models, Biological, Neoplasm Metastasis, Nitric Oxide, Stilbenes, Transcription Factor AP-1
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/22q3f1sg
-
3
المساهمون: Mühendislik ve Doğa Bilimleri Fakültesi -- Biyomedikal Mühendisliği Bölümü, Nur, Gökhan
المصدر: Open Medicine. 17:1788-1796
مصطلحات موضوعية: Protein bcl 2, Mouse, Imidacloprid, animal experiment, Histopathology, glomerulus, animal cell, Eosin, Kidney, Acetamiprid, animal tissue, Kidney distal tubule, Neonicotinoids, Immunoreactivity, Toxic dose, General & Internal Medicine, Formaldehyde, Bcl-2, Nicotinic Receptors, Hematoxylin, Nephrotoxicity, Protein p53, Kidney hemorrhage, P53, kidney capsule, apoptosis, Kidney tissue, Kidney proximal tubule, General Medicine, Nonhuman, Bioaccumulation, immunohistochemistry, Proximal tubule cell, Degeneration, Distal tubule cell, Protein expression, Kidney epithelium, Atrophy, Controlled study
وصف الملف: application/pdf
-
4
المؤلفون: Ufuk Demirci, Hakkı Onur Kırkızlar, Elif G. Ümit, Vildan Gürsoy, İbrahim Ethem Pınar, Fahir Özkalemkaş, Zeynep Tuğba Güven, Leylagül Kaynar, Fatma Keklik Karadağ, Güray Saydam, Ömer Ekinci, Mustafa Merter, Merih Reis Aras, Murat Albayrak, Sedanur Karaman Gülsaran, Volkan Baş, Berrin Balık Aydın, Hüseyin Saffet Beköz, Ferda Can, İmdat Dilek, Özgür Mehtap, Erman Öztürk, Bengü Çöbanoğlu Şimşek, Murat Yıldırım, Meltem Aylı, Ünal Ataş, Ozan Salim, Mesut Ayer, Elif Birtaş Ateşoğlu, Olga Meltem Akay, Meltem Kurt Yüksel, Semra Paydaş, Selçuk Korkmaz, Fulya Öz Puyan, Ahmet Muzaffer Demir
مصطلحات موضوعية: Histology, protein bcl 2, overall survival, very elderly, interferon regulatory factor 4, CD 5, protein bcl 6, Article, Pathology and Forensic Medicine, male, Double/triple expressor, human, fluorescence in situ hybridization, CD20 antigen, progression free survival, cyclophosphamide plus doxorubicin plus etoposide plus prednisolone plus rituximab plus vincristine, ECOG Performance Status, adult, lactate dehydrogenase, Hematology, Diffuse large B-cell lymphoma, CNS prophylaxis, major clinical study, diffuse large B cell lymphoma, CD5 antigen, aged, c-MYC, common acute lymphoblastic leukemia antigen, female, Myc protein, CD3 antigen, Ki 67 antigen, pathology, prognosis, cyclophosphamide plus doxorubicin plus prednisolone plus rituximab plus vincristine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc5afcfe2c14a3c1913655d10fc99b8
https://hdl.handle.net/11454/79471 -
5
المؤلفون: Seyma Aydinlik, Muhittin Aygün, Veysel T. Yilmaz, Ceyda Icsel
المساهمون: Bursa Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Kimya Bölümü., Bursa Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Biyoloji Bölümü., İçsel, Ceyda, Aydınlık, Şeyma, Yılmaz, Veysel Turan, ABI-2909-2020, AAI-3342-2021, 2-s2.0-85087758658
مصطلحات موضوعية: Cell viability, Protein bcl 2, Pyridines, Coordination complexes, Apoptosis, Manganese, IC50, Targeting mitochondria, 01 natural sciences, Anticancer activity, Saccharin, Chemical structure, Drug Discovery, Antineoplastic agents, 2,6-bis(benzimidazol-2-yl)pyridine, Enzyme activity, Vivtro DNA-binding, Pyridine derivative, Cell proliferation, Saccharin derivative, chemistry.chemical_classification, 0303 health sciences, Structure activity relation, General Medicine, Manganese derivative, Antineoplastic agent, Drug screening, Molecular docking, Dose-response relationship, drug, Cell membrane depolarization, Drug stability, Human, Saccharinate, Double-strand breaks, Article, Tumor cell culture, Metal, 03 medical and health sciences, Drug synthesis, Pyridine, Dose response, Humans, Pharmacology, Cisplatin, 010405 organic chemistry, Pharmacology & pharmacy, Tumor cells, cultured, Copper, 0104 chemical sciences, Drug effect, Human cell, Oxidative stress, Benzimidazoles, 2,6 bis(2 benzimidazolyl)pyridine derivative, Unclassified drug, Enzyme activation, Antiproliferative activity, MCF-7 cell line, Cobalt complex, Cell survival, chemistry.chemical_compound, Nickel complex, Synthesis, Protein expression level, Iron complex, Caspase 7, DNA cleavage, HT-29 cell line, Chemistry, Caspase 3, Copper complex, Cancer-cells, Ligand cu(II) complexes, Plasmid DNA, Double stranded DNA break, Drug screening assays, antitumor, Heavy metal, visual_art, A-549 cell line, visual_art.visual_art_medium, Tumor necrosis factor receptor superfamily member 6, Chemistry, medicinal, Cobalt, Coordination compound, medicine.drug, Drug cytotoxicity, chemistry.chemical_element, Antineoplastic metal complex, MCF-10A cell line, G1 phase cell cycle checkpoint, 2,6-Bis(2-benzimidazolyl)pyridine, medicine, Benzimidazole derivative, DNA binding, Mitochondrion, 030304 developmental biology, Antineoplastic activity, Hydrogen bond, Reactive oxygen species, Cytotoxic activity, Protein Bax, Organic Chemistry, In vitro study, Structure-activity relationship, Complex, Palladium, 2-Phenylpyridine, Cell-cycle, Metals, heavy, Nickel, Ray crystal-structure, Structural-characterization, Molecular structure, Reactive oxygen metabolite, Controlled study, Nuclear chemistry, First row divalent transition metals, Mitochondrial membrane
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09f8f485e05165cb7e96f206ba578ff6
http://hdl.handle.net/11452/29620 -
6
المؤلفون: Kubilay Inci, Pervin Elvan Tokgun, Onur Tokgun, Hakan Akca
مصطلحات موضوعية: Cancer Research, Lung Neoplasms, Overexpression, cyclin D1, Apoptosis, MYC, UCA1 gene, E2F4AS gene, SNHG6 gene, Western blotting, Small hairpin RNA, 0302 clinical medicine, cell growth assay, HOTAIR gene, transcription factor Sox2, Tumor Cells, Cultured, PVT1 gene, Inhibition, MEG3, 0303 health sciences, MALAT1, Molecular Structure, Cell Cycle, Neat1 gene, apoptosis, SCLC, HOTAIR, Cell cycle, cell invasion, PVT1, unclassified drug, ANRIL gene, oncogene myc, real time polymerase chain reaction, 030220 oncology & carcinogenesis, Molecular Medicine, RNA, Long Noncoding, cell cycle, Lentiviral vector, lentivirus vector, down regulation, H19 gene, protein bcl 2, gene overexpression, long untranslated RNA, Sox2OT gene, Antineoplastic Agents, Biology, SNHG3 gene, Article, Malat1 gene, Proto-Oncogene Proteins c-myc, 03 medical and health sciences, Structure-Activity Relationship, L1PA16 gene, nerve cell adhesion molecule, Cancer stem cell, GAS5 gene, Humans, BC200 gene, controlled study, human, gene, AK23948 gene, 030304 developmental biology, Cell Proliferation, Pharmacology, Dose-Response Relationship, Drug, SFMBT2 gene, human cell, MEG3 gene, PTENP1 gene, ZEB2NAT gene, Small Cell Lung Carcinoma, LncRNA, cell proliferation, Myc protein, Cancer research, gene expression, small cell lung cancer, GAS5, Drug Screening Assays, Antitumor, ALDH1A1 gene
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20079bd974296d67b84c4cb236f078ee
-
7
مصطلحات موضوعية: Chalcone, SnoRNA, Epithelial-Mesenchymal Transition, Angiogenesis, Apoptosis, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Chalcones, Downregulation and upregulation, Cell Movement, Cell Line, Tumor, Drug Discovery, Humans, 030304 developmental biology, Cell Proliferation, Pharmacology, 0303 health sciences, 1 [4 (methylsulfonyl)phenyl] 3 (2,4,6 trimethoxyphenyl)prop 2 en 1 one, 1 [4 (methylthio)phenyl] 3 (2,4,6 trimethoxyphenyl)prop 2 en 1 one, 1 [4 (methylthio)phenyl] 3 [3 (trifluoromethyl)phenyl]prop 2 en 1 one, 3 (2 methoxyphenyl) 1 [4 (methylsulfonyl)phenyl]prop 2 en 1 one, 3 (2,5 dimethoxyphenyl) 1 [4 (methylsulfonyl)phenyl]prop 2 en 1 one, 3 (6 bromobenzo[d][1,3]dioxol 5 yl) 1 [4 (methylsulfonyl)phenyl]prop 2 en 1 one, 3 (6 bromobenzo[d][1,3]dioxol 5 yl) 1 [4 (methylthio)phenyl]prop 2 en 1 one, 3 (6 bromobenzo[d][1,3]dioxol 5 yl) 1 [4 (piperazin 1 yl)phenyl]prop 2 en 1 one, 3 (benzo[b]thiophen 2 yl) 1 (3 methoxyphenyl)prop 2 en 1 one, 3 (benzo[b]thiophen 2 yl) 1 (3,4,5 trimethoxyphenyl)prop 2 en 1 one, 3 (benzo[b]thiophen 2 yl) 1 (benzo[d][1,3]dioxol 5 yl)prop 2 en 1 one, 3 (benzo[b]thiophen 2 yl) 1 [4 (methylsulfonyl)phenyl]prop 2 en 1 one, 3 (benzo[b]thiophen 2 yl) 1 [4 (methylthio)phenyl]prop 2 en 1 one, 3 [2 fluoro 4 (trifluoromethyl)phenyl] 1 [4 (methylthio)phenyl]prop 2 en 1 one, antineoplastic agent, B Raf kinase, beta catenin, chalcone derivative, fascin, paclitaxel, protein Bax, protein bcl 2, unclassified drug, uvomorulin, vimentin, KRAS protein, human, protein p21, antiangiogenic activity, antineoplastic activity, apoptosis, Article, BRAF gene, cancer inhibition, cell adhesion, cell cycle, cell viability, colony formation, colorectal cancer, controlled study, down regulation, drug design, drug effect, drug efficacy, drug potency, drug potentiation, drug screening, drug selectivity, drug synthesis, epithelial mesenchymal transition, gene mutation, GI50, HCT 116 cell line, HT-29 cell line, immortalized cell line, in vitro study, in vivo study, LoVo cell line, metastasis, migration inhibition, oncogene K ras, priority journal, proapoptotic activity, process optimization, tumor invasion, tumor suppressor gene, tumor vascularization, upregulation, cell motion, cell proliferation, chemistry, colorectal tumor, genetics, human, tumor cell line, Colorectal Neoplasms, SARS-CoV-2, COVID-19, Cell migration, Cell cycle, digestive system diseases, Cell culture, 030220 oncology & carcinogenesis, Catenin, Cancer cell, Cancer research, MiRNA, Biomarkers
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adc1236da4f974eb1d8b09b484eb060e
https://hdl.handle.net/10576/38686 -
8
المؤلفون: Ala-Eddin Al Moustafa, Dana Elkhalifa, Mohammed H. Qusa, Feras Q. Alali, Farhan S. Cyprian, Abu Bakar Siddique, Ashraf A. Khalil, Khalid A. El Sayed
المصدر: European journal of medicinal chemistry. 187
مصطلحات موضوعية: Models, Molecular, Chalcone, Cell cycle checkpoint, Cell Survival, Nitrogen, Mice, Nude, Cancer progression, Apoptosis, Triple Negative Breast Neoplasms, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, Mice, Structure-Activity Relationship, 1 (3 chlorophenyl) 3 [4 (pyrrolidin 1 yl)phenyl]prop 2 en 1 one, 1 (3 methoxyphenyl) 3 [4 (piperidin 1 yl)phenyl]prop 2 en 1 one, 1 (3 methoxyphenyl) 3 [4 (pyrrolidin 1 yl)phenyl]prop 2 en 1 one, 1 (benzo[d][1,3]dioxol 5 yl) 3 [4 (pyrrolidin 1 yl)phenyl]prop 2 en 1 one, 1 [4 (methylsulfonyl)phenyl] 3 (4 morpholinophenyl)prop 2 en 1 one, 1 [4 (methylsulfonyl)phenyl] 3 [4 (piperidin 1 yl)phenyl]prop 2 en 1 one, 1 [4 (methylsulfonyl)phenyl] 3 [4 (pyrrolidin 1 yl)phenyl]prop 2 en 1 one, 1 [4 (methylthio)phenyl) 3 [4 (piperidin 1 yl)phenyl]prop 2 en 1 one, 1 [4 (methylthio)phenyl] 3 (4 morpholinophenyl)prop 2 en 1 one, 1 [4 (methylthio)phenyl] 3 [4 (pyrrolidin 1 yl)phenyl]prop 2 en 1 one, 3 (4 morpholinophenyl) 1 [4 (piperazin 1 yl) phenyl)prop 2 en 1 one, 3 [4 [bis(2 chloroethyl)amino]phenyl] 1 (2 methoxyphenyl)prop 2 en 1 one, 3 [4 [bis(2 chloroethyl)amino]phenyl] 1 [4 (methylsulfonyl)phenyl]prop 2 en 1 one, antineoplastic agent, chalcone derivative, chlormethine, colchicine, estrogen, morpholine, P cadherin, paclitaxel, piperidine derivative, protein Bax, protein bcl 2, pyrrolidine derivative, unclassified drug, uvomorulin, vasculotropin receptor 2, [3 [4 [bis(2 chloroethyl)amino]phenyl] 1 (3 methoxyphenyl)prop 2 en 1 one], chalcone, nitrogen, angiogenesis, animal cell, animal experiment, animal model, antineoplastic activity, antiproliferative activity, apoptosis, Article, cancer inhibition, cell invasion, cell migration, chorioallantois, clinical effectiveness, clinical evaluation, colony formation, comparative study, concentration response, controlled study, cytotoxicity, down regulation, drug design, drug efficacy, drug identification, drug synthesis, epithelial mesenchymal transition, G2 phase cell cycle checkpoint, human, human cell, IC50, in vivo study, MCF-7 cell line, MDA-MB-231 cell line, MDA-MB-468 cell line, mouse, nonhuman, triple negative breast cancer, tumor xenograft, upregulation, animal, cell cycle checkpoint, cell proliferation, cell survival, chemical structure, chemistry, dose response, drug effect, drug screening, experimental mammary neoplasm, female, molecular model, nude mouse, pathology, structure activity relation, synthesis, tumor cell culture, Animals, Cell Cycle Checkpoints, Cell Proliferation, Dose-Response Relationship, Drug, Drug Design, Drug Screening Assays, Antitumor, Female, Humans, Mammary Neoplasms, Experimental, Molecular Structure, Tumor Cells, Cultured, Nude mouse, Drug Discovery, Epithelial–mesenchymal transition, Triple-negative breast cancer, 030304 developmental biology, Pharmacology, E-cadherin/catenin complex and its signaling pathways, 0303 health sciences, biology, 010405 organic chemistry, Oral cancer, Organic Chemistry, Emt, General Medicine, biology.organism_classification, Nitrogen mustard, 0104 chemical sciences, Cell culture, Cancer research
-
9
المؤلفون: Ayça Üvez, Mattia Mori, Konstantinos Dimas, Cinzia Ingallina, Pınar Alper, Chrisiida Tsimplouli, Ilaria D'Acquarica, Nazlihan Aztopal, Merve Erkisa, Elif Ilkay Armutak, Bruno Botta, Bulent Ozpolat, Simone Berardozzi, Evangelia Sereti, Didem Karakas, Buse Cevatemre, Ebru Gürel Gürevin, Engin Ulukaya
المساهمون: Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Biyoloji Bölümü., Cevatemre, Buse, Erkısa, Merve, Aztopal, Nazlıhan, Karakaş, Didem, Alper, Pınar, AHD-2050-2022, AAM-1001-2020, L-6687-2018, L-6682-2018, İstinye Üniversitesi, Rektörlük, Didem Karakaş / 0000-0002-3781-6834, Engin Ulukaya / 0000-0003-4875-5472, Merve Erkısa Genel / 0000-0002-3127-742X, Pınar Alper / 0000-0001-9631-3551, Erkisa Genel, Merve, Karakaş Zeybek, Didem, Ulukaya, Engin, Didem Karakaş / L-6682-2018, Engin Ulukaya / K-5792-2018, Merve Erkısa Genel / AAM-1001-2020, Pınar Alper / DUL-1586-2022, Didem Karakaş / 56422040600, Engin Ulukaya / 6602927353, Merve Erkısa Genel / 57126208900, Pınar Alper / 57197858774
المصدر: Pharmacological Research. 129:500-514
مصطلحات موضوعية: 0301 basic medicine, Palladium(ıı), Protein bcl 2, Unclassified drug, Mouse, Proliferation, Enzyme activation, Apoptosis, Antiproliferative activity, IC50, MCF-7 cell line, Experimental mammary neoplasm, Cell vacuole, Animal tissue, Metastasis, Western blotting, Biological product, Unfolded protein response, Degradation, Mice, In vivo study, Breast cancer, 0302 clinical medicine, Antineoplastic agents, Cytotoxic T cell, Flow cytometry, Priority journal, Caspase 7, education.field_of_study, Signaling pathway, Caspase 3, Chemistry, Neoplastic stem cells, Antineoplastic agent, Protein cleavage, Drug screening, Sesquiterpene, Pristimerin, Maytenus, 030220 oncology & carcinogenesis, Sequestosome 1, cytoplasmic vacuolation, endoplasmic reticulum stress, Female, triterpenoid, Stem cell, Pentacyclic Triterpenes, Animal cell, Drug mechanism, Xenograft model antitumor assays, Human, Drug cytotoxicity, Programmed cell death, Microtubule associated protein, Microtubule associated protein 1A 1B light chain 3B, mammosphere, Population, Article, 03 medical and health sciences, Cancer stem cell, Autophagy, Animals, Humans, Animal model, Drug dose comparison, Biological products, Animal experiment, ATPase activity assay, education, Antineoplastic activity, Pharmacology, Pharmacology & pharmacy, Animal, Carcinoma, In vitro study, Tumor cell line, Nonhuman, Triterpenes, Mammary neoplasms, experimental, Drug effect, Drug efficacy, Cell line, tumor, 030104 developmental biology, Human cell, Doxorubicin, Cancer cell, Cancer research, Protein expression, Tumor xenograft, Triterpene, Controlled study, Phosphatidylinositol 3 kinase
وصف الملف: application/pdf
-
10
المؤلفون: Canan Eroğlu, Yavuz Dodurga, Mücahit Seçme, Oğuzhan Kaygusuz, Ömer Faruk Çolak, Pelin Atmaca
المصدر: International Journal of Medicinal Mushrooms. 20:1075-1086
مصطلحات موضوعية: Basidiomycetes, cell migration, protein p53, cyclin D1, XTT assay, Apoptosis, Pharmacology, fluorescence microscopy, Applied Microbiology and Biotechnology, Anticancer activity, Macrolepiota procera extract, inhibitory concentration, Western blotting, cell motion, Cell Movement, caspase 3, morphology, Drug Discovery, Cytotoxic T cell, A549 cells, caspase 9, antineoplastic agent, TUNEL assay, biology, messenger RNA, Chemistry, drug effect, unclassified drug, RNA isolation, PUMA protein, cell cycle arrest, real time polymerase chain reaction, A-549 cell line, Medicinal mushrooms, cytotoxicity, down regulation, protein Bax, antiproliferative activity, protein bcl 2, Cell Survival, Antineoplastic Agents, antineoplastic activity, chemistry, protein Noxa, Article, reverse transcription polymerase chain reaction, basidiospore, matrigel chamber assay, Humans, cyclin dependent kinase 6, controlled study, Neoplasm Invasiveness, human, Macrolepiota procera, protein expression, cyclin dependent kinase 4, A549 cell, cell culture, Matrigel, nonhuman, protein p21, human cell, Basidiomycota, phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase, fungal extract, tumor invasion, biology.organism_classification, Cell culture, Cancer cell, gene expression, protein kinase B, cell invasion assay, Agaricales, upregulation
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6024737e9be57f538fe5a82e1e1b04
https://doi.org/10.1615/intjmedmushrooms.2018028589