يعرض 1 - 10 نتائج من 734 نتيجة بحث عن '"proteolysis-targeting chimera"', وقت الاستعلام: 3.41s تنقيح النتائج
  1. 1
    دورية أكاديمية

    المؤلفون: Zhang R; Shandong Provincial Key Laboratory of Animal Resistance Biology, Center for Cell Structure and Function, College of Life Sciences, Shandong Normal University, Jinan, China., Xie S; Shandong Provincial Key Laboratory of Animal Resistance Biology, Center for Cell Structure and Function, College of Life Sciences, Shandong Normal University, Jinan, China., Ran J; Shandong Provincial Key Laboratory of Animal Resistance Biology, Center for Cell Structure and Function, College of Life Sciences, Shandong Normal University, Jinan, China., Li T; Haihe Laboratory of Cell Ecosystem, State Key Laboratory of Medicinal Chemical Biology, Department of Genetics and Cell Biology, College of Life Sciences, Nankai University, Tianjin, China.

    المصدر: Journal of cellular physiology [J Cell Physiol] 2024 May; Vol. 239 (5), pp. e31255. Date of Electronic Publication: 2024 Mar 19.

    نوع المنشور: Journal Article; Review

    بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0050222 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4652 (Electronic) Linking ISSN: 00219541 NLM ISO Abbreviation: J Cell Physiol Subsets: MEDLINE

  2. 2
    دورية أكاديمية

    المؤلفون: Wu M; Hangzhou Institute of Innovative Medicine, Institute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, PR China. Electronic address: wmfayd@163.com., Wang W; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences; Zhejiang University, Cancer Center; Zhejiang University School of Medicine Children'sHospital, Division of Hematology-Oncology, Hangzhou, 310058, PR China., Mao X; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences; Zhejiang University, Cancer Center; Zhejiang University School of Medicine Children'sHospital, Division of Hematology-Oncology, Hangzhou, 310058, PR China., Wu Y; Hangzhou Institute of Innovative Medicine, Institute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, PR China., Jin Y; Key Laboratory of Neuropsychiatric Drug Research of Zhejiang Province, Hangzhou Medical College, Hangzhou, 310058, PR China., Liu T; Hangzhou Institute of Innovative Medicine, Institute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, PR China., Lu Y; Department of Pharmacy, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, PR China., Dai H; Department of Pharmacy, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, PR China., Zeng S; Key Laboratory of Neuropsychiatric Drug Research of Zhejiang Province, Hangzhou Medical College, Hangzhou, 310058, PR China., Huang W; Key Laboratory of Neuropsychiatric Drug Research of Zhejiang Province, Hangzhou Medical College, Hangzhou, 310058, PR China., Wang Y; College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, 712046, PR China., Yao X; Centre for Artificial Intelligence Driven Drug Discovery, Faculty of Applied Sciences, Macao Polytechnic University, Macau, 999078, PR China., Che J; Hangzhou Institute of Innovative Medicine, Institute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, PR China. Electronic address: chejx@zju.edu.cn., Ying M; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences; Zhejiang University, Cancer Center; Zhejiang University School of Medicine Children'sHospital, Division of Hematology-Oncology, Hangzhou, 310058, PR China. Electronic address: mying@zju.edu.cn., Dong X; Hangzhou Institute of Innovative Medicine, Institute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, PR China; Department of Pharmacy, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, PR China. Electronic address: dongxw@zju.edu.cn.

    المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2024 Sep 05; Vol. 275, pp. 116539. Date of Electronic Publication: 2024 May 31.

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

  3. 3
    دورية أكاديمية

    المؤلفون: Xiao B; Department of Chemistry, Tsinghua University, Beijing 100084, China; The State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China., Shi Z; Institute of Biomedical Health Technology and Engineering, Shenzhen Bay Laboratory, Shenzhen, 518132, China., Liu J; Institute of Biomedical Health Technology and Engineering, Shenzhen Bay Laboratory, Shenzhen, 518132, China., Huang Q; Department of Chemistry, Tsinghua University, Beijing 100084, China; The State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China., Shu K; The State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China., Liu F; Institute of Biomedical Health Technology and Engineering, Shenzhen Bay Laboratory, Shenzhen, 518132, China., Zhi C; Institute of Biomedical Health Technology and Engineering, Shenzhen Bay Laboratory, Shenzhen, 518132, China., Zhang D; Institute of Biomedical Health Technology and Engineering, Shenzhen Bay Laboratory, Shenzhen, 518132, China., Wu L; The State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China., Yang S; Institute of Biomedical Health Technology and Engineering, Shenzhen Bay Laboratory, Shenzhen, 518132, China., Zeng X; The State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China., Fan T; Institute of Biomedical Health Technology and Engineering, Shenzhen Bay Laboratory, Shenzhen, 518132, China. Electronic address: fantt@szbl.ac.cn., Liu Z; Shenzhen Kivita Innovative Drug Discovery Institute, Shenzhen 518057, China; Shenzhen Winkey Technology Co., Ltd., Shenzhen 518000, China. Electronic address: liuzijian1115@163.com., Jiang Y; The State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China; Institute of Biomedical Health Technology and Engineering, Shenzhen Bay Laboratory, Shenzhen, 518132, China; School of Pharmaceutical Sciences, Tsinghua University, Beijing, 100084, China. Electronic address: jiangyy@sz.tsinghua.edu.cn.

    المصدر: Bioorganic chemistry [Bioorg Chem] 2024 Feb; Vol. 143, pp. 107078. Date of Electronic Publication: 2024 Jan 02.

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

  4. 4
    دورية أكاديمية

    المؤلفون: Price E; Research and Development, AbbVie Inc., 1 North Waukegan Road, North Chicago, Illinois 60064, United States., Weinheimer M; Research and Development, AbbVie Inc., 1 North Waukegan Road, North Chicago, Illinois 60064, United States., Rivkin A; Research and Development, AbbVie Inc., 1 North Waukegan Road, North Chicago, Illinois 60064, United States., Jenkins G; Research and Development, AbbVie Inc., 1 North Waukegan Road, North Chicago, Illinois 60064, United States., Nijsen M; Research and Development, AbbVie Inc., 1 North Waukegan Road, North Chicago, Illinois 60064, United States., Cox PB; Research and Development, AbbVie Inc., 1 North Waukegan Road, North Chicago, Illinois 60064, United States., DeGoey D; Research and Development, AbbVie Inc., 1 North Waukegan Road, North Chicago, Illinois 60064, United States.

    المصدر: Journal of medicinal chemistry [J Med Chem] 2024 Apr 11; Vol. 67 (7), pp. 5683-5698. Date of Electronic Publication: 2024 Mar 18.

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

  5. 5
    دورية أكاديمية

    المؤلفون: Apprato G; Department of Molecular Biotechnology and Health Sciences, University of Torino, Piazza Nizza 44bis, 10126 Torino, Italy., Poongavanam V; Department of Chemistry - BMC, Uppsala University, SE-75123 Uppsala, Sweden., Garcia Jimenez D; Department of Molecular Biotechnology and Health Sciences, University of Torino, Piazza Nizza 44bis, 10126 Torino, Italy., Atilaw Y; Department of Chemistry - BMC, Uppsala University, SE-75123 Uppsala, Sweden., Erdelyi M; Department of Chemistry - BMC, Uppsala University, SE-75123 Uppsala, Sweden., Ermondi G; Department of Molecular Biotechnology and Health Sciences, University of Torino, Piazza Nizza 44bis, 10126 Torino, Italy., Caron G; Department of Molecular Biotechnology and Health Sciences, University of Torino, Piazza Nizza 44bis, 10126 Torino, Italy. Electronic address: giulia.caron@unito.it., Kihlberg J; Department of Chemistry - BMC, Uppsala University, SE-75123 Uppsala, Sweden. Electronic address: jan.kihlberg@kemi.uu.se.

    المصدر: Drug discovery today [Drug Discov Today] 2024 Apr; Vol. 29 (4), pp. 103917. Date of Electronic Publication: 2024 Feb 14.

    نوع المنشور: Journal Article; Review

    بيانات الدورية: Publisher: Elsevier Science Ltd. Country of Publication: England NLM ID: 9604391 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5832 (Electronic) Linking ISSN: 13596446 NLM ISO Abbreviation: Drug Discov Today Subsets: MEDLINE

  6. 6
    دورية أكاديمية

    المؤلفون: Li H; State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China., Chai M; State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China; Key Laboratory of Functional Molecular Solids, Ministry of Education, Anhui Laboratory of Molecule-Based Materials, College of Chemistry and Materials Science, Anhui Normal University, Wuhu 241000, China., Chen Y; State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China., Zhou F; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Discovery of Chinese Ministry of Education (MOE), Guangzhou City Key Laboratory of Precision Chemical Drug Development, College of Pharmacy, Jinan University, Guangzhou 511400, China., Ren X; State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China., Xu J; Livzon Research Institute, Livzon Pharmaceutical Group Inc., Zhuhai 519000, China., Wang J; Key Laboratory of Functional Molecular Solids, Ministry of Education, Anhui Laboratory of Molecule-Based Materials, College of Chemistry and Materials Science, Anhui Normal University, Wuhu 241000, China. Electronic address: wang_jian989@163.com., Wang Z; State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China; Ningbo Zhongke Creation Center of New Materials, Ningbo 315000, China. Electronic address: wangz@sioc.ac.cn., Huang W; State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China; Ningbo Zhongke Creation Center of New Materials, Ningbo 315000, China. Electronic address: wxhuang@sioc.ac.cn.

    المصدر: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2024 Apr 01; Vol. 103, pp. 117661. Date of Electronic Publication: 2024 Mar 02.

    نوع المنشور: Clinical Trial, Phase I; Journal Article

    بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

  7. 7
    دورية أكاديمية

    المؤلفون: Hu Z; Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06511, USA.; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China., Chen PH; Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06511, USA.; Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, Tainan City, 701, Taiwan.; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan City, 701, Taiwan., Li W; Yale Cancer Biology Institute, Yale University, West Haven, CT 06516, USA., Krone M; Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06511, USA., Zheng S; Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06511, USA., Saarbach J; Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06511, USA., Velasco IU; Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06511, USA., Hines J; Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06511, USA., Liu Y; Yale Cancer Biology Institute, Yale University, West Haven, CT 06516, USA., Crews CM; Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06511, USA.; Department of Chemistry, Yale University, New Haven, CT 06511, USA.; Department of Pharmacology, Yale University, New Haven, CT 06511, USA.; Yale University School of Medicine, New Haven, CT 06511, USA.

    المصدر: Science advances [Sci Adv] 2024 Mar 29; Vol. 10 (13), pp. eadj7251. Date of Electronic Publication: 2024 Mar 27.

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

  8. 8
    دورية أكاديمية

    المؤلفون: Desantis J; Department of Chemistry, Biology, and Biotechnology, University of Perugia, Italy., Bazzacco A; Department of Molecular Medicine, University of Padua, Padua, Italy., Eleuteri M; Department of Chemistry, Biology, and Biotechnology, University of Perugia, Italy., Tuci S; Department of Molecular Medicine, University of Padua, Padua, Italy., Bianconi E; Department of Pharmaceutical Science, University of Perugia, Italy., Macchiarulo A; Department of Pharmaceutical Science, University of Perugia, Italy., Mercorelli B; Department of Molecular Medicine, University of Padua, Padua, Italy. Electronic address: beatrice.mercorelli@unipd.it., Loregian A; Department of Molecular Medicine, University of Padua, Padua, Italy. Electronic address: arianna.loregian@unipd.it., Goracci L; Department of Chemistry, Biology, and Biotechnology, University of Perugia, Italy. Electronic address: laura.goracci@unipg.it.

    المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2024 Mar 15; Vol. 268, pp. 116202. Date of Electronic Publication: 2024 Feb 06.

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

  9. 9
    دورية أكاديمية

    المؤلفون: Wang X; School of Environmental Ecology and Biological Engineering, Wuhan Institute of Technology, Wuhan, 430205, China; College of Life Sciences, Wuchang University of Technology, Wuhan, Hubei Province, 430223, China., Xin L; State Key Laboratory of Virology, Frontier Science Center for Immunology and Metabolism, Hubei Province Engineering and Technology Research Center for Fluorinated Pharmaceuticals, Wuhan University School of Pharmaceutical Sciences, Wuhan, 430071, China., Deng X; State Key Laboratory of Virology, Frontier Science Center for Immunology and Metabolism, Hubei Province Engineering and Technology Research Center for Fluorinated Pharmaceuticals, Wuhan University School of Pharmaceutical Sciences, Wuhan, 430071, China., Dong C; State Key Laboratory of Virology, Frontier Science Center for Immunology and Metabolism, Hubei Province Engineering and Technology Research Center for Fluorinated Pharmaceuticals, Wuhan University School of Pharmaceutical Sciences, Wuhan, 430071, China., Hu G; School of Environmental Ecology and Biological Engineering, Wuhan Institute of Technology, Wuhan, 430205, China. Electronic address: msnhm123@gmail.com., Zhou HB; State Key Laboratory of Virology, Frontier Science Center for Immunology and Metabolism, Hubei Province Engineering and Technology Research Center for Fluorinated Pharmaceuticals, Wuhan University School of Pharmaceutical Sciences, Wuhan, 430071, China. Electronic address: zhouhb@whu.edu.cn.

    المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2024 Mar 05; Vol. 267, pp. 116184. Date of Electronic Publication: 2024 Feb 01.

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

  10. 10
    دورية أكاديمية

    المؤلفون: Lu X; Shanghai Frontiers Science Center for Chinese Medicine Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, China.; Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai, China.; State Key Laboratory of New Drug and Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry, China State Institute of Pharmaceutical Industry, Shanghai, China., Jin J; Shanghai Frontiers Science Center for Chinese Medicine Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, China., Wu Y; Shanghai Frontiers Science Center for Chinese Medicine Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, China., Liu X; Shanghai Frontiers Science Center for Chinese Medicine Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, China., Liang X; Shanghai Frontiers Science Center for Chinese Medicine Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, China., Lin J; Shanghai Frontiers Science Center for Chinese Medicine Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, China., Sun Q; State Key Laboratory of New Drug and Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry, China State Institute of Pharmaceutical Industry, Shanghai, China., Qin J; The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, China., Zhang W; Shanghai Frontiers Science Center for Chinese Medicine Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, China.; State Key Laboratory of New Drug and Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry, China State Institute of Pharmaceutical Industry, Shanghai, China., Luan X; Shanghai Frontiers Science Center for Chinese Medicine Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

    المصدر: Medicinal research reviews [Med Res Rev] 2024 Mar; Vol. 44 (2), pp. 812-832. Date of Electronic Publication: 2023 Nov 27.

    نوع المنشور: Journal Article; Review

    بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 8103150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-1128 (Electronic) Linking ISSN: 01986325 NLM ISO Abbreviation: Med Res Rev Subsets: MEDLINE

    مواضيع طبية MeSH: Proteolysis Targeting Chimera*, Humans ; Kinetics ; Mutation