المؤلفون: van der Pol A; Department of Cardiology, University Medical Center Groningen, University of Groningen, AV Groningen, The Netherlands.; Division of Perioperative Inflammation and Infection, Department of Human Medicine, Faculty of Medicine and Health Sciences, University of Oldenburg, Oldenburg, Germany., Gil A; Department of Pharmacy, Analytical Biochemistry, University of Groningen, Groningen, The Netherlands., Tromp J; Department of Cardiology, University Medical Center Groningen, University of Groningen, AV Groningen, The Netherlands.; National Heart Centre Singapore, Singapore, Singapore., Silljé HHW; Department of Cardiology, University Medical Center Groningen, University of Groningen, AV Groningen, The Netherlands., van Veldhuisen DJ; Department of Cardiology, University Medical Center Groningen, University of Groningen, AV Groningen, The Netherlands., Voors AA; Department of Cardiology, University Medical Center Groningen, University of Groningen, AV Groningen, The Netherlands., Hoendermis ES; Department of Cardiology, University Medical Center Groningen, University of Groningen, AV Groningen, The Netherlands., Grote Beverborg N; Department of Cardiology, University Medical Center Groningen, University of Groningen, AV Groningen, The Netherlands., Schouten EM; Department of Cardiology, University Medical Center Groningen, University of Groningen, AV Groningen, The Netherlands., de Boer RA; Department of Cardiology, University Medical Center Groningen, University of Groningen, AV Groningen, The Netherlands., Bischoff R; Department of Pharmacy, Analytical Biochemistry, University of Groningen, Groningen, The Netherlands., van der Meer P; Department of Cardiology, University Medical Center Groningen, University of Groningen, AV Groningen, The Netherlands.

المصدر: Cardiovascular research [Cardiovasc Res] 2018 Dec 01; Vol. 114 (14), pp. 1871-1882.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print Cited Medium: Internet ISSN: 1755-3245 (Electronic) Linking ISSN: 00086363 NLM ISO Abbreviation: Cardiovasc Res Subsets: MEDLINE

مواضيع طبية MeSH: Ventricular Function, Left* , Ventricular Pressure* , Ventricular Remodeling*, Heart Failure/*enzymology , Myocardial Reperfusion Injury/*enzymology , Myocardium/*enzymology , Pyroglutamate Hydrolase/*deficiency , Pyrrolidonecarboxylic Acid/*metabolism, Aged ; Aged, 80 and over ; Animals ; Case-Control Studies ; Disease Models, Animal ; Female ; Fibrosis ; Genetic Predisposition to Disease ; Heart Failure/genetics ; Heart Failure/pathology ; Heart Failure/physiopathology ; Humans ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Middle Aged ; Myocardial Reperfusion Injury/genetics ; Myocardial Reperfusion Injury/pathology ; Myocardial Reperfusion Injury/physiopathology ; Myocardium/pathology ; Oxidative Stress ; Phenotype ; Pyroglutamate Hydrolase/genetics ; Randomized Controlled Trials as Topic ; Signal Transduction

المؤلفون: Yang P; State Key Laboratory for Ecological Pest Control of Fujian and Taiwan Crops, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, 350002, China., Chen Y; State Key Laboratory for Ecological Pest Control of Fujian and Taiwan Crops, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, 350002, China., Wu H; Fujian University Key Laboratory for Plant-Microbe Interaction, College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, 350002, China., Fang W; State Key Laboratory for Ecological Pest Control of Fujian and Taiwan Crops, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, 350002, China., Liang Q; State Key Laboratory for Ecological Pest Control of Fujian and Taiwan Crops, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, 350002, China., Zheng Y; Fujian University Key Laboratory for Plant-Microbe Interaction, College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, 350002, China., Olsson S; State Key Laboratory for Ecological Pest Control of Fujian and Taiwan Crops, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.; Plant Immunity Center, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, 350002, China., Zhang D; State Key Laboratory for Ecological Pest Control of Fujian and Taiwan Crops, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, 350002, China., Zhou J; Fujian University Key Laboratory for Plant-Microbe Interaction, College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, 350002, China., Wang Z; State Key Laboratory for Ecological Pest Control of Fujian and Taiwan Crops, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, 350002, China. wangzh@fafu.edu.cn.; Ocean College, Minjiang University, Fuzhou, 350108, China. wangzh@fafu.edu.cn., Zheng W; State Key Laboratory for Ecological Pest Control of Fujian and Taiwan Crops, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, 350002, China. wenhuiz@fafu.edu.cn.

المصدر: Current genetics [Curr Genet] 2018 Feb; Vol. 64 (1), pp. 285-301. Date of Electronic Publication: 2017 Sep 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer International Country of Publication: United States NLM ID: 8004904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0983 (Electronic) Linking ISSN: 01728083 NLM ISO Abbreviation: Curr Genet Subsets: MEDLINE

مواضيع طبية MeSH: Spores, Fungal*, Fusarium/*physiology , Pyroglutamate Hydrolase/*metabolism , Trichothecenes/*biosynthesis, Biological Evolution ; Cell Wall/genetics ; Cell Wall/metabolism ; Computational Biology/methods ; Fungal Proteins/genetics ; Fungal Proteins/metabolism ; Fusarium/pathogenicity ; Genetic Complementation Test ; Mutation ; Phylogeny ; Protein Transport ; Pyroglutamate Hydrolase/genetics ; Virulence/genetics ; Virulence Factors/genetics ; Virulence Factors/metabolism

المؤلفون: Crisp T; Emergency Department Registrar, Southern District Health Board, Dunedin., Sizeland P; Renal Physician, Waikato District Health Board, Hamilton., Du Toit S; Chemical Pathologist, Waikato District Health Board, Hamilton., Chan LW; Renal Physician, Waikato District Health Board, Hamilton.

المصدر: The New Zealand medical journal [N Z Med J] 2021 Nov 26; Vol. 134 (1546), pp. 117-121. Date of Electronic Publication: 2021 Nov 26.

نوع المنشور: Case Reports

بيانات الدورية: Publisher: Pasifika Medical Association Group Country of Publication: New Zealand NLM ID: 0401067 Publication Model: Electronic Cited Medium: Internet ISSN: 1175-8716 (Electronic) Linking ISSN: 00288446 NLM ISO Abbreviation: N Z Med J Subsets: MEDLINE

مواضيع طبية MeSH: Acetaminophen/*adverse effects , Acidosis/*chemically induced , Pyroglutamate Hydrolase/*metabolism, Acid-Base Equilibrium ; Aged ; Analgesics, Non-Narcotic/adverse effects ; Bicarbonates/administration & dosage ; Female ; Humans ; New Zealand

المؤلفون: Li X; Department of Pediatrics, Peking University First Hospital, Beijing 100034, China., Ding Y; Department of Pediatrics, Peking University First Hospital, Beijing 100034, China., Liu Y; Department of Pediatrics, Peking University First Hospital, Beijing 100034, China., Ma Y; Department of Pediatrics, Peking University First Hospital, Beijing 100034, China., Song J; Department of Pediatrics, Peking University First Hospital, Beijing 100034, China., Wang Q; Department of Pediatrics, Peking University First Hospital, Beijing 100034, China., Yang Y; Department of Pediatrics, Peking University First Hospital, Beijing 100034, China. Electronic address: yanlingy@vip.sina.com.

المصدر: Brain & development [Brain Dev] 2015 Nov; Vol. 37 (10), pp. 952-9. Date of Electronic Publication: 2015 Apr 04.

نوع المنشور: Case Reports; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909235 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7131 (Electronic) Linking ISSN: 03877604 NLM ISO Abbreviation: Brain Dev Subsets: MEDLINE

مواضيع طبية MeSH: Amino Acid Metabolism, Inborn Errors/*urine , Glutathione Synthase/*deficiency , Hydroxyproline/*urine , Pyroglutamate Hydrolase/*deficiency, Amino Acid Metabolism, Inborn Errors/diagnosis ; Amino Acid Metabolism, Inborn Errors/genetics ; Amino Acid Metabolism, Inborn Errors/metabolism ; Asian People ; Case-Control Studies ; Child, Preschool ; China ; Female ; Genetic Predisposition to Disease ; Glutathione Synthase/genetics ; Glutathione Synthase/metabolism ; Glutathione Synthase/urine ; Humans ; Infant ; Infant, Newborn ; Male ; Mutation ; Pyroglutamate Hydrolase/genetics ; Pyroglutamate Hydrolase/metabolism ; Pyroglutamate Hydrolase/urine

SCR Disease Name: 5-oxoprolinase deficiency; Glutathione synthetase deficiency

المؤلفون: Zagorski, Karen, King, Olga, Hovakimyan, Armine, Petrushina, Irina, Antonyan, Tatevik, Chailyan, Gor, Ghazaryan, Manush, Hyrc, Krzysztof L, Chadarevian, Jean Paul, Davtyan, Hayk, Blurton-Jones, Mathew, Cribbs, David H, Agadjanyan, Michael G, Ghochikyan, Anahit

المصدر: International journal of molecular sciences. 24(12)

مصطلحات موضوعية: Brain, Animals, Mice, Transgenic, Mice, Alzheimer Disease, Disease Models, Animal, Pyrrolidonecarboxylic Acid, Cancer Vaccines, Immunotherapy, Amyloid beta-Peptides, Plaque, Amyloid, Alzheimer’s disease, post-translational modification, prevention, pyroglutamate, vaccine, Neurodegenerative, Immunization, Vaccine Related, Dementia, Alzheimer's Disease, Aging, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Neurosciences, Acquired Cognitive Impairment, Prevention, Biotechnology, Brain Disorders, Aetiology, 3.4 Vaccines, Prevention of disease and conditions, and promotion of well-being, 2.1 Biological and endogenous factors, Neurological, Good Health and Well Being, Alzheimer's disease, Other Chemical Sciences, Genetics, Other Biological Sciences, Chemical Physics

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5jf405z4

المؤلفون: Calpena E; Program in Rare and Genetic Diseases, Centro de Investigación Príncipe Felipe (CIPF), Valencia, Spain, ecalpena@cipf.es., Deshpande AA, Yap S, Kumar A, Manning NJ, Bachhawat AK, Espinós C

المصدر: European journal of pediatrics [Eur J Pediatr] 2015 Mar; Vol. 174 (3), pp. 407-11. Date of Electronic Publication: 2014 Aug 17.

نوع المنشور: Case Reports; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7603873 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1076 (Electronic) Linking ISSN: 03406199 NLM ISO Abbreviation: Eur J Pediatr Subsets: MEDLINE

مواضيع طبية MeSH: Mutation, Missense*, Amino Acid Metabolism, Inborn Errors/*genetics , Pyroglutamate Hydrolase/*deficiency, Female ; Genes, Recessive ; Genetic Predisposition to Disease ; Heterozygote ; Humans ; Infant ; Pyroglutamate Hydrolase/genetics

SCR Disease Name: 5-oxoprolinase deficiency

المؤلفون: Oke M; Department of Biological Sciences, Fountain University, Osogbo, Nigeria., Oni O; Department of Chemical Sciences, Fountain University, Osogbo, Nigeria., Bello R; Department of Chemical Sciences, Fountain University, Osogbo, Nigeria., Samuel-Omoyajowo K; Department of Biological Sciences, Fountain University, Osogbo, Nigeria., Senbadejo T; Department of Biological Sciences, Fountain University, Osogbo, Nigeria.

المصدر: Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology [Biochem Mol Biol Educ] 2019 Nov; Vol. 47 (6), pp. 620-631. Date of Electronic Publication: 2019 Sep 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & sons Country of Publication: United States NLM ID: 100970605 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1539-3429 (Electronic) Linking ISSN: 14708175 NLM ISO Abbreviation: Biochem Mol Biol Educ Subsets: MEDLINE

مواضيع طبية MeSH: Biological Science Disciplines/*education , Computational Biology/*education , Pyroglutamate Hydrolase/*chemistry , Pyroglutamate Hydrolase/*metabolism, Curriculum ; Glutamic Acid/chemistry ; Glutamic Acid/metabolism ; Humans ; Models, Molecular ; Pyrrolidonecarboxylic Acid/chemistry ; Pyrrolidonecarboxylic Acid/metabolism ; Structure-Activity Relationship ; Students

المؤلفون: Bachhawat AK; Department of Biological Sciences, Indian Institute of Science Education and Research, Mohali, S.A.S. Nagar, Punjab 140306, India., Yadav S; Department of Biological Sciences, Indian Institute of Science Education and Research, Mohali, S.A.S. Nagar, Punjab 140306, India., Jainarayanan AK; Department of Biological Sciences, Indian Institute of Science Education and Research, Mohali, S.A.S. Nagar, Punjab 140306, India., Dubey P; Department of Biological Sciences, Indian Institute of Science Education and Research, Mohali, S.A.S. Nagar, Punjab 140306, India.

المصدر: The Biochemical journal [Biochem J] 2020 Sep 18; Vol. 477 (17), pp. 3123-3130.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE

مواضيع طبية MeSH: Endoplasmic Reticulum Stress* , Oxidative Stress*, Glutathione/*metabolism , Heart Failure/*metabolism, Animals ; Heart Failure/pathology ; Humans ; Pyroglutamate Hydrolase/metabolism ; Pyrrolidonecarboxylic Acid/metabolism ; gamma-Glutamylcyclotransferase/metabolism

المؤلفون: Kumar A; Institute of Microbial Technology (CSIR), Chandigarh, India., Bachhawat AK

المصدر: FEMS yeast research [FEMS Yeast Res] 2010 Jun; Vol. 10 (4), pp. 394-401. Date of Electronic Publication: 2010 Mar 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 101085384 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1567-1364 (Electronic) Linking ISSN: 15671356 NLM ISO Abbreviation: FEMS Yeast Res Subsets: MEDLINE

مواضيع طبية MeSH: Adenosine Triphosphate/*metabolism , Pyroglutamate Hydrolase/*genetics , Pyroglutamate Hydrolase/*metabolism , Saccharomyces cerevisiae/*enzymology , Saccharomyces cerevisiae/*genetics , Saccharomyces cerevisiae Proteins/*genetics , Saccharomyces cerevisiae Proteins/*metabolism, Adenosine Triphosphatases/genetics ; Adenosine Triphosphatases/metabolism ; Binding Sites ; Dimerization ; Gene Expression ; Glutamic Acid/metabolism ; Kinetics ; Models, Molecular ; Protein Binding ; Protein Structure, Tertiary ; Pyroglutamate Hydrolase/isolation & purification ; Pyrrolidonecarboxylic Acid/analogs & derivatives ; Pyrrolidonecarboxylic Acid/metabolism ; Recombinant Proteins/genetics ; Recombinant Proteins/isolation & purification ; Recombinant Proteins/metabolism ; Saccharomyces cerevisiae Proteins/isolation & purification ; Sulfur/metabolism

المؤلفون: Almaghlouth IA; Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia., Mohamed JY, Al-Amoudi M, Al-Ahaidib L, Al-Odaib A, Alkuraya FS

المصدر: Clinical genetics [Clin Genet] 2012 Aug; Vol. 82 (2), pp. 193-6. Date of Electronic Publication: 2011 Jun 30.

نوع المنشور: Case Reports; Journal Article

بيانات الدورية: Publisher: Munksgaard Country of Publication: Denmark NLM ID: 0253664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1399-0004 (Electronic) Linking ISSN: 00099163 NLM ISO Abbreviation: Clin Genet Subsets: MEDLINE

مواضيع طبية MeSH: Mutation*, Amino Acid Metabolism, Inborn Errors/*genetics , Pyroglutamate Hydrolase/*genetics, Base Sequence ; Frameshift Mutation ; Heterozygote ; Humans ; Infant ; Male ; Pyroglutamate Hydrolase/deficiency

SCR Disease Name: 5-oxoprolinase deficiency