المؤلفون: Székvölgyi L; MTA-DE Momentum, Genome Architecture and Recombination Research Group, Department of Molecular and Nanopharmaceutics, Faculty of Pharmacy, University of Debrecen, Debrecen, 4032, Hungary. lorantsz@med.unideb.hu.

المصدر: Biologia futura [Biol Futur] 2024 Jun; Vol. 75 (2), pp. 177-182. Date of Electronic Publication: 2024 Mar 08.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101738236 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2676-8607 (Electronic) Linking ISSN: 26768607 NLM ISO Abbreviation: Biol Futur Subsets: MEDLINE

مواضيع طبية MeSH: R-Loop Structures*, Humans ; Genomic Instability/genetics ; Animals

المؤلفون: Kassab MA; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, 91010, USA. muzaffer.kassab@pennmedicine.upenn.edu.; Present address: Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. muzaffer.kassab@pennmedicine.upenn.edu., Chen Y; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, 91010, USA.; Present address: Therapeutics Discovery Division, The University of Texas MD Anderson Cancer Center, Houston, TX, 77054, USA., Wang X; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, 91010, USA.; Present address: Westlake University, Hangzhou, Zhejiang, P. R. China., He B; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, 91010, USA.; Present address: Division of Cellular and Developmental Biology, Department of Molecular and Cell Biology, University of California, Berkeley, CA, 94705, USA., Brown EJ; Present address: Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Yu X; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, 91010, USA. yuxiaochun@westlake.edu.cn.; Present address: Westlake University, Hangzhou, Zhejiang, P. R. China. yuxiaochun@westlake.edu.cn.

المصدر: BMC biology [BMC Biol] 2024 Jul 08; Vol. 22 (1), pp. 151. Date of Electronic Publication: 2024 Jul 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101190720 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7007 (Electronic) Linking ISSN: 17417007 NLM ISO Abbreviation: BMC Biol Subsets: MEDLINE

مواضيع طبية MeSH: Immunoglobulin Class Switching*/genetics , Cytidine Deaminase*/metabolism , Cytidine Deaminase*/genetics , Cytidine Deaminase*/chemistry , R-Loop Structures*, Animals ; Mice ; Methylation ; Immunoglobulin Heavy Chains/genetics ; Immunoglobulin Heavy Chains/metabolism ; Recombination, Genetic ; RNA/metabolism ; RNA/genetics

المؤلفون: Wang C; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol and Guangzhou Key Laboratory of Healthy Aging, School of Lifesciences, Sun Yat-sen University, Guangzhou 510275, China.; Department of Oncology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510275, China., Huang Y; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol and Guangzhou Key Laboratory of Healthy Aging, School of Lifesciences, Sun Yat-sen University, Guangzhou 510275, China., Yang Y; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol and Guangzhou Key Laboratory of Healthy Aging, School of Lifesciences, Sun Yat-sen University, Guangzhou 510275, China.; Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China., Li R; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol and Guangzhou Key Laboratory of Healthy Aging, School of Lifesciences, Sun Yat-sen University, Guangzhou 510275, China., Li Y; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol and Guangzhou Key Laboratory of Healthy Aging, School of Lifesciences, Sun Yat-sen University, Guangzhou 510275, China., Qiu H; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol and Guangzhou Key Laboratory of Healthy Aging, School of Lifesciences, Sun Yat-sen University, Guangzhou 510275, China., Wu J; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol and Guangzhou Key Laboratory of Healthy Aging, School of Lifesciences, Sun Yat-sen University, Guangzhou 510275, China., Shi G; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol and Guangzhou Key Laboratory of Healthy Aging, School of Lifesciences, Sun Yat-sen University, Guangzhou 510275, China., Ma W; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol and Guangzhou Key Laboratory of Healthy Aging, School of Lifesciences, Sun Yat-sen University, Guangzhou 510275, China., Songyang Z; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol and Guangzhou Key Laboratory of Healthy Aging, School of Lifesciences, Sun Yat-sen University, Guangzhou 510275, China.; Department of Oncology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510275, China.

المصدر: Protein & cell [Protein Cell] 2024 Jul 01; Vol. 15 (7), pp. 493-511.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: Germany NLM ID: 101532368 Publication Model: Print Cited Medium: Internet ISSN: 1674-8018 (Electronic) Linking ISSN: 1674800X NLM ISO Abbreviation: Protein Cell Subsets: MEDLINE

مواضيع طبية MeSH: Telomere*/metabolism , Telomere*/genetics , Nuclear Factor 90 Proteins*/metabolism , Nuclear Factor 90 Proteins*/genetics , Homologous Recombination* , R-Loop Structures*/genetics, Humans ; DEAD-box RNA Helicases/metabolism ; DEAD-box RNA Helicases/genetics ; HEK293 Cells ; Telomere Homeostasis

المؤلفون: Wen C; State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, Shandong, 250012, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, Shandong, 250012, China.; Shandong Technology Innovation Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250012, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), Jinan, Shandong, 250012, China., Cao L; State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, Shandong, 250012, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, Shandong, 250012, China.; Shandong Technology Innovation Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250012, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), Jinan, Shandong, 250012, China., Wang S; State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, Shandong, 250012, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, Shandong, 250012, China.; Shandong Technology Innovation Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250012, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), Jinan, Shandong, 250012, China., Xu W; State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, Shandong, 250012, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, Shandong, 250012, China.; Shandong Technology Innovation Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250012, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), Jinan, Shandong, 250012, China., Yu Y; State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, Shandong, 250012, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, Shandong, 250012, China.; Shandong Technology Innovation Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250012, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), Jinan, Shandong, 250012, China., Zhao S; State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, Shandong, 250012, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, Shandong, 250012, China.; Shandong Technology Innovation Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250012, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), Jinan, Shandong, 250012, China., Yang F; Advanced Medical Research Institute, Meili Lake Translational Research Park, Cheeloo College of Medicine, Shandong University, Jinan, China.; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Shandong University, Jinan, Shandong, 250012, China., Chen ZJ; State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, Shandong, 250012, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, Shandong, 250012, China.; Shandong Technology Innovation Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250012, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), Jinan, Shandong, 250012, China.; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, China.; Department of Reproductive Medicine, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhao S; State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China. shidouzhao@sdu.edu.cn.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, Shandong, 250012, China. shidouzhao@sdu.edu.cn.; Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, Shandong, 250012, China. shidouzhao@sdu.edu.cn.; Shandong Technology Innovation Center for Reproductive Health, Jinan, Shandong, 250012, China. shidouzhao@sdu.edu.cn.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, Shandong, 250012, China. shidouzhao@sdu.edu.cn.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250012, China. shidouzhao@sdu.edu.cn.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), Jinan, Shandong, 250012, China. shidouzhao@sdu.edu.cn., Yang Y; State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China. YangYJ0204@sdu.edu.cn.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, Shandong, 250012, China. YangYJ0204@sdu.edu.cn.; Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, Shandong, 250012, China. YangYJ0204@sdu.edu.cn.; Shandong Technology Innovation Center for Reproductive Health, Jinan, Shandong, 250012, China. YangYJ0204@sdu.edu.cn.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, Shandong, 250012, China. YangYJ0204@sdu.edu.cn.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250012, China. YangYJ0204@sdu.edu.cn.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), Jinan, Shandong, 250012, China. YangYJ0204@sdu.edu.cn., Qin Y; State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China. qinyingying@sdu.edu.cn.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, Shandong, 250012, China. qinyingying@sdu.edu.cn.; Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, Shandong, 250012, China. qinyingying@sdu.edu.cn.; Shandong Technology Innovation Center for Reproductive Health, Jinan, Shandong, 250012, China. qinyingying@sdu.edu.cn.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, Shandong, 250012, China. qinyingying@sdu.edu.cn.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250012, China. qinyingying@sdu.edu.cn.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), Jinan, Shandong, 250012, China. qinyingying@sdu.edu.cn.

المصدر: The EMBO journal [EMBO J] 2024 Jul; Vol. 43 (14), pp. 3044-3071. Date of Electronic Publication: 2024 Jun 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

مواضيع طبية MeSH: DEAD-box RNA Helicases*/metabolism , DEAD-box RNA Helicases*/genetics , Minichromosome Maintenance Proteins*/metabolism , Minichromosome Maintenance Proteins*/genetics , Genomic Instability* , R-Loop Structures*/genetics, Animals ; Mice ; Female ; Humans ; Germ Cells/metabolism ; DNA Damage ; Male

المؤلفون: Hao JD; Key Laboratory of RNA Science and Engineering, CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China., Liu QL; Key Laboratory of RNA Science and Engineering, CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address: liuqianlan@big.ac.cn., Liu MX; Key Laboratory of RNA Science and Engineering, CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China; Sino-Danish College, University of Chinese Academy of Sciences, Beijing 101408, China., Yang X; Key Laboratory of RNA Science and Engineering, CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China., Wang LM; Key Laboratory of RNA Science and Engineering, CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China., Su SY; Key Laboratory of RNA Science and Engineering, CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China; School of Future Technology, University of Chinese Academy of Sciences, Beijing 100049, China., Xiao W; Key Laboratory of RNA Science and Engineering, CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China., Zhang MQ; Key Laboratory of RNA Science and Engineering, CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China., Zhang YC; Key Laboratory of RNA Science and Engineering, CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China., Zhang L; Key Laboratory of RNA Science and Engineering, CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China; Sino-Danish College, University of Chinese Academy of Sciences, Beijing 101408, China., Chen YS; Key Laboratory of RNA Science and Engineering, CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China., Yang YG; Key Laboratory of RNA Science and Engineering, CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China. Electronic address: ygyang@big.ac.cn., Ren J; Key Laboratory of RNA Science and Engineering, CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China; Sino-Danish College, University of Chinese Academy of Sciences, Beijing 101408, China; School of Future Technology, University of Chinese Academy of Sciences, Beijing 100049, China; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China. Electronic address: renjie@big.ac.cn.

المصدر: Molecular cell [Mol Cell] 2024 May 02; Vol. 84 (9), pp. 1711-1726.e11. Date of Electronic Publication: 2024 Apr 02.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

مواضيع طبية MeSH: Adenosine*/*analogs & derivatives, DEAD-box RNA Helicases*/metabolism , DEAD-box RNA Helicases*/genetics , Methyltransferases*/metabolism , Methyltransferases*/genetics , Genomic Instability* , Adenosine*/metabolism , Adenosine*/genetics , Exoribonucleases*/metabolism , Exoribonucleases*/genetics , Transcription Termination, Genetic* , R-Loop Structures* , RNA Polymerase II*/metabolism , RNA Polymerase II*/genetics, Humans ; HEK293 Cells ; Chromatin/metabolism ; Chromatin/genetics ; DNA Damage ; HeLa Cells ; RNA/metabolism ; RNA/genetics ; Transcription, Genetic ; RNA Methylation

المؤلفون: Watanabe H; Department of Agricultural Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan., Urano S; Department of Agricultural Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan., Kikuchi N; Department of Agricultural Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan., Kubo Y; Department of Agricultural Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan., Kikuchi A; Department of Agricultural Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan., Gomi K; Department of Agricultural Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan., Shintani T; Department of Agricultural Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan. Electronic address: takahiro.shintani.d7@tohoku.ac.jp.

المصدر: The Journal of biological chemistry [J Biol Chem] 2024 May; Vol. 300 (5), pp. 107274. Date of Electronic Publication: 2024 Apr 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Saccharomyces cerevisiae*/metabolism , Saccharomyces cerevisiae*/genetics , Saccharomyces cerevisiae Proteins*/metabolism , Saccharomyces cerevisiae Proteins*/genetics , Vacuoles*/metabolism , Vacuoles*/genetics , R-SNARE Proteins*/metabolism , R-SNARE Proteins*/genetics, Membrane Fusion ; Exocytosis ; SNARE Proteins/metabolism ; SNARE Proteins/genetics ; Mutation

المؤلفون: Lay MA; Department of Pharmacology, University of Arizona, Tucson, Arizona, USA.; University of Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA.; Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona, USA., Thompson VF; Department of Pharmacology, University of Arizona, Tucson, Arizona, USA.; University of Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA., Adelakun AD; Department of Pharmacology, University of Arizona, Tucson, Arizona, USA.; University of Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA.; Department of Pharmaceutical Sciences, University of Arizona, Tucson, Arizona, USA., Schwartz JC; Department of Pharmacology, University of Arizona, Tucson, Arizona, USA.; University of Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA.

المصدر: Biopolymers [Biopolymers] 2024 May; Vol. 115 (3), pp. e23576. Date of Electronic Publication: 2024 Mar 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 0372525 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0282 (Electronic) Linking ISSN: 00063525 NLM ISO Abbreviation: Biopolymers Subsets: MEDLINE

مواضيع طبية MeSH: RNA-Binding Protein EWS*/metabolism , RNA-Binding Protein EWS*/chemistry , RNA-Binding Protein EWS*/genetics , DNA*/metabolism , DNA*/chemistry , R-Loop Structures*, Humans ; Protein Binding ; Sarcoma, Ewing/metabolism ; Sarcoma, Ewing/genetics ; Zinc Fingers ; RNA-Binding Proteins/metabolism ; RNA-Binding Proteins/chemistry ; RNA-Binding Proteins/genetics ; Electrophoretic Mobility Shift Assay

المؤلفون: Yang BZ; Department and Graduate Institute of Pharmacology, College of Medicine, National Taiwan University, Taipei, 100233, Taiwan., Liu MY; Department and Graduate Institute of Pharmacology, College of Medicine, National Taiwan University, Taipei, 100233, Taiwan., Chiu KL; Institute of Molecular and Cellular Biology, National Taiwan University, Taipei, 106319, Taiwan., Chien YL; Department and Graduate Institute of Pharmacology, College of Medicine, National Taiwan University, Taipei, 100233, Taiwan., Cheng CA; Department and Graduate Institute of Pharmacology, College of Medicine, National Taiwan University, Taipei, 100233, Taiwan., Chen YL; Department and Graduate Institute of Pharmacology, College of Medicine, National Taiwan University, Taipei, 100233, Taiwan., Tsui LY; Department and Graduate Institute of Pharmacology, College of Medicine, National Taiwan University, Taipei, 100233, Taiwan., Lin KR; Department and Graduate Institute of Pharmacology, College of Medicine, National Taiwan University, Taipei, 100233, Taiwan., Chu HC; Institute of Molecular and Cellular Biology, National Taiwan University, Taipei, 106319, Taiwan., Wu CP; Department and Graduate Institute of Pharmacology, College of Medicine, National Taiwan University, Taipei, 100233, Taiwan. cswu2017@ntu.edu.tw.

المصدر: Nature communications [Nat Commun] 2024 Jul 17; Vol. 15 (1), pp. 6009. Date of Electronic Publication: 2024 Jul 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Sumoylation* , DEAD-box RNA Helicases*/metabolism , DEAD-box RNA Helicases*/genetics , Genomic Instability* , R-Loop Structures*, Humans ; HEK293 Cells ; DNA Damage ; Poly (ADP-Ribose) Polymerase-1/metabolism ; Poly (ADP-Ribose) Polymerase-1/genetics ; Lysine/metabolism ; Mutation ; Small Ubiquitin-Related Modifier Proteins/metabolism ; Small Ubiquitin-Related Modifier Proteins/genetics ; Neoplasm Proteins

المؤلفون: Zhang X; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA, USA., Xu J; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.; Genetics and Metabolism Department, The Children's Hospital, School of Medicine, Zhejiang University, National Clinical Research Center for Child Health, Hangzhou, China.; The Institute of Translational Medicine, School of Medicine, Zhejiang University, Hangzhou, China., Hu J; Sichuan Provincial Key Laboratory for Human Disease Gene Study, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China., Zhang S; National Institute of Biological Sciences,7 Science Park Road, Beijing, China., Hao Y; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.; China National Center for Bioinformation, Beijing, China.; Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, 100049, Beijing, China., Zhang D; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA, USA., Qian H; Sichuan Provincial Key Laboratory for Human Disease Gene Study, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China., Wang D; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA. dow003@health.ucsd.edu.; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA, USA. dow003@health.ucsd.edu.; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA. dow003@health.ucsd.edu., Fu XD; Westlake Laboratory of Life Sciences and Biomedicine, School of Life Sciences and School of Medicine, Westlake University, Hangzhou, Zhejiang, China. fuxiangdong@westlake.edu.cn.

المصدر: Nature communications [Nat Commun] 2024 Jul 17; Vol. 15 (1), pp. 6031. Date of Electronic Publication: 2024 Jul 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Cockayne Syndrome*/genetics , Cockayne Syndrome*/pathology , Cockayne Syndrome*/metabolism , RNA Polymerase II*/metabolism , RNA Polymerase II*/genetics , Poly-ADP-Ribose Binding Proteins*/genetics , Poly-ADP-Ribose Binding Proteins*/metabolism , DNA Repair Enzymes*/metabolism , DNA Repair Enzymes*/genetics , DNA Helicases*/metabolism , DNA Helicases*/genetics , Genomic Instability* , R-Loop Structures*/genetics, Animals ; Humans ; Mice ; DNA Repair ; Transcription Elongation, Genetic ; Mice, Knockout

المؤلفون: Wulfridge P; Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, PA, USA.; Penn Epigenetics Institute, University of Pennsylvania, Philadelphia, PA, USA., Sarma K; Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, PA, USA. kavitha@sarmalab.com.; Penn Epigenetics Institute, University of Pennsylvania, Philadelphia, PA, USA. kavitha@sarmalab.com.

المصدر: Nature cell biology [Nat Cell Biol] 2024 Jul; Vol. 26 (7), pp. 1025-1036. Date of Electronic Publication: 2024 Jun 24.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE

مواضيع طبية MeSH: G-Quadruplexes* , DNA Repair* , R-Loop Structures*/genetics , Transcription, Genetic*, Humans ; Animals ; DNA/metabolism ; DNA/genetics ; DNA/chemistry ; Genome/genetics ; Gene Regulatory Networks ; RNA/metabolism ; RNA/genetics ; RNA/chemistry ; Neoplasms/genetics ; Neoplasms/pathology ; Neoplasms/metabolism