-
1رسالة جامعية
المؤلفون: Nyström, Susanne
مصطلحات موضوعية: DNA-PK; DNA double-stranded break, DSB; DNA single-stranded break, SSB; DNA damage; ionizing radiation, IR; DNA repair; calicheamicin gamma1; bleomycin; etoposide; topoisomerase II; radiotherapy; radiosensitizer; ATM, DNA, DNA repair, Protein kinases, DNA-binding proteins -- chemistry, DNA-binding proteins -- metabolism, DNA damage -- drug effects, DNA repair -- drug effects, raf kinases -- antagonists & inhibitors, raf kinases -- chemistry, raf kinases -- metabolism, Indoles -- pharmacology, DNA -- chemistry, DNA -- drug effects, DNA -- metabolism, Aminoglycosides -- chemistry, Aminoglycosides -- pharmacology
Degree: Diss. (sammanfattning) Göteborg : Univ., 2005
-
2
المؤلفون: Loana Musso, Raquel T. Lima, Raffaella Cincinelli, Ana Bizarro, Michelandrea De Cesare, Sabrina Dallavalle, M. Helena Vasconcelos, Valentina Zuco, Diana Sousa
المساهمون: Instituto de Investigação e Inovação em Saúde
المصدر: Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 23, Iss 2, p 407 (2018)
Molecules; Volume 23; Issue 2; Pages: 407
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAPمصطلحات موضوعية: Skin Neoplasms, Skin Neoplasms / drug therapy, Antineoplastic Agents / pharmacology, Apoptosis, 01 natural sciences, Analytical Chemistry, Inhibitor of Apoptosis Proteins, Mice, HSP90 Heat-Shock Proteins / metabolism, Drug Discovery, Carcinoma, Squamous Cell / drug therapy, HSP90 Heat-Shock Proteins / antagonists & inhibitors, Cell Cycle, raf Kinases / antagonists & inhibitors, Benzopyrans / chemical synthesis, 3. Good health, Tumor Burden, Gene Expression Regulation, Neoplastic, Cyclin-Dependent Kinase 4 / genetics, Chemistry (miscellaneous), Carcinoma, Squamous Cell, Growth inhibition, Pyridones, Proto-Oncogene Proteins c-akt / metabolism, Antineoplastic Agents, Apoptosis / drug effects, tumor xenographs, Article, (thio)chromenopyridinones, 03 medical and health sciences, Inhibitory Concentration 50, Cyclin-Dependent Kinase 4 / metabolismo, Proto-Oncogene Proteins c-akt / genetics, lcsh:Organic chemistry, Humans, Benzopyrans, raf Kinases / metabolism, Apoptosis / genetics, Isoxazoles, Proto-Oncogene Proteins c-akt / antagonists & inhibitors, 0104 chemical sciences, 030104 developmental biology, chemistry, Inhibitor of Apoptosis Proteins / genetics, Pyridones / pharmacology, 0301 basic medicine, Carcinoma, Squamous Cell / genetics, Survivin, Pharmaceutical Science, raf Kinases / genetics, chemistry.chemical_compound, HSP90, naphthoquinones, antitumor, cell proliferation, cell cycle, apoptosis, Carcinoma, Squamous Cell / pathology, Antineoplastic Agents / chemical synthesis, Benzopyrans / pharmacology, Skin Neoplasms / genetics, Inhibitor of Apoptosis Proteins / antagonists & inhibitors, biology, Cell cycle, Cyclin-Dependent Kinase 4 / antagonists & inhibitors, Hsp90, Molecular Medicine, Female, raf Kinases, Signal transduction, Signal Transduction, Carcinoma, Squamous Cell / metabolism, Isoxazoles / pharmacology, Mice, Nude, Cell Cycle / drug effects, Skin Neoplasms / metabolismo, lcsh:QD241-441, Isoxazoles / chemical synthesis, Tumor Burden / drug effects, Heat shock protein, Cell Line, Tumor, Animals, HSP90 Heat-Shock Proteins, Physical and Theoretical Chemistry, Cell Proliferation, Skin Neoplasms / pathology, Pyridones / chemical synthesis, Cell growth, Organic Chemistry, Cyclin-Dependent Kinase 4, Xenograft Model Antitumor Assays, Inhibitor of Apoptosis Proteins / metabolism, 010404 medicinal & biomolecular chemistry, HSP90 Heat-Shock Proteins / genetics, Cell culture, Cancer research, biology.protein, Cell Proliferation / drug effects, Proto-Oncogene Proteins c-akt
وصف الملف: application/pdf
-
3
المؤلفون: Daniel C. Hoessli, Afshan Kaleem, Evelyne Walker-Nasir, Ishtiaq Ahmad, Abdul Rauf Shakoori, Nasir-ud-Din
المصدر: Journal of Cellular Biochemistry, Vol. 108, No 4 (2009) pp. 816-824
مصطلحات موضوعية: In silico, Molecular Sequence Data, ddc:616.07, medicine.disease_cause, Biochemistry, Acetylglucosamine, Mice, raf Kinases/ metabolism, medicine, Animals, Humans, Amino Acid Sequence, Phosphorylation, Nuclear protein, Molecular Biology, GTPase-Activating Proteins/chemistry, Cell Nucleus, Neurofibromin 1, Acetylglucosamine/chemistry, Sequence Homology, Amino Acid, biology, GTPase-Activating Proteins, Neurofibromin 1/ chemistry, Cell Biology, Protein Structure, Tertiary, Cell biology, Ras Signaling Pathway, Cell Nucleus/metabolism, ras Proteins/ metabolism, ras Proteins, biology.protein, raf Kinases, Signal transduction, Carcinogenesis, Protein Processing, Post-Translational, Function (biology), Protein Binding, Signal Transduction
-
4
المصدر: Nature communications
Chakraborty, A, Diefenbacher, M E, Mylona, A, Kassel, O & Behrens, A 2015, ' The E3 ubiquitin ligase Trim7 mediates c-Jun/AP-1 activation by Ras signalling ', Nature Communications, vol. 6, 6782 . https://doi.org/10.1038/ncomms7782مصطلحات موضوعية: Lung Neoplasms, Proto-Oncogene Proteins c-jun, medicine.medical_treatment, General Physics and Astronomy, Carrier Proteins/metabolism, Apoptosis, Proto-Oncogene Proteins c-myc/metabolism, Tripartite Motif Proteins, Mice, Ubiquitin, Anti-apoptotic Ras signalling cascade, Phosphorylation, Gene knockdown, Multidisciplinary, biology, Ubiquitin ligase, Cell biology, raf Kinases/metabolism, raf Kinases, Protein stabilization, Signal transduction, Proto-Oncogene Proteins c-jun/metabolism, Signal Transduction, ras Proteins/metabolism, MAP Kinase Signaling System, Ubiquitin-Protein Ligases, Mice, Transgenic, Ribosomal Protein S6 Kinases, 90-kDa, Article, General Biochemistry, Genetics and Molecular Biology, Proto-Oncogene Proteins c-myc, Ubiquitin-Protein Ligases/metabolism, Cell Line, Tumor, medicine, Animals, Humans, Trans-Activators/metabolism, Transcription factor, Cell Proliferation, Growth factor, Ubiquitination, General Chemistry, Transcription Factor AP-1, HEK293 Cells, Ribosomal Protein S6 Kinases, 90-kDa/metabolism, Trans-Activators, ras Proteins, biology.protein, Cancer research, Lung Neoplasms/metabolism, Transcription Factor AP-1/metabolism, Carrier Proteins, Neoplasm Transplantation, HeLa Cells
وصف الملف: application/pdf
-
5
المؤلفون: Timo K. van den Berg, Elena Kostova, Robin van Bruggen, Pasi Halonen, Thomas R. L. Klei, Boukje M. Beuger, Cor Lieftink, Roderick L. Beijersbergen
المساهمون: Molecular cell biology and Immunology, Graduate School, AII - Amsterdam institute for Infection and Immunity, General Internal Medicine, Landsteiner Laboratory
المصدر: Bioscience Reports
Bioscience Reports, Vol 35, Iss 2, p e00187 (2015)
Kostova, E B, Beuger, B M, Klei, T R L, Halonen, P, Lieftink, C, Beijersbergen, R, van den Berg, T K & van Bruggen, R 2015, ' Identification of signalling cascades involved in red blood cell shrinkage and vesiculation ', Frontiers in Bioscience, vol. 35, no. 2 . https://doi.org/10.1042/BSR20150019
Frontiers in Bioscience, 35(2). Frontiers in Bioscience
Bioscience reports, 35(2). Portland Press Ltd.مصطلحات موضوعية: Erythrocytes, lcsh:Life, lcsh:QR1-502, red blood cell, Cellular Senescence/drug effects, Biochemistry, lcsh:Microbiology, PC, phosphatidylcholine, ERK, extracellular signal-regulated kinase, Cell-Derived Microparticles, Casein Kinase II/metabolism, Jak, Janus kinase, Anaplastic lymphoma kinase, ASK1, Casein Kinase II, Cellular Senescence, CaM, calmodulin, PDGFR, platelet-derived growth factor receptor, AMPK, AMP-activated kinase, Kinase, Ionomycin, RBC, red blood cell, PS, phosphatidylserine, Cell biology, raf Kinases/metabolism, STAT, signal transducer and activator of transcription, Calcium Ionophores, VEGFR, vascular endothelial growth factor receptor, raf Kinases, Casein kinase 2, RTK, receptor tyrosine kinase, SCD, sickle cell disease, Cell aging, PI3K, phosphoinositide 3-kinase, SMase, acid sphingomyelinase, kinase inhibitor, Calcium Ionophores/pharmacology, SAGM, saline-adenine-glucose-mannitol, Biophysics, Biology, ATA, aurintricarboxylic acid, Cell-Derived Microparticles/metabolism, PLC, phospholipase C, bioactive small molecule, PKC, protein kinase C, MEK, mitogen-activated protein kinase kinase, Humans, Protein kinase A, Molecular Biology, Protein kinase B, GPCR, G protein-coupled receptor, BCR-ABL, breakpoint cluster region protein–Abelson murine leukaemia viral oncogene homologue 1, Original Paper, NO, nitric oxide, compound screen, Ionomycin/pharmacology, β-AR, β-adrenergic receptor, Kinase insert domain receptor, Cell Biology, Erythrocytes/cytology, vesiculation, LOPAC, Library of Pharmacologically Active Compounds, nRTK, non-receptor tyrosine kinase, CK2, casein kinase 2, lcsh:QH501-531, Epo, erythropoietin, MAPK, mitogen-activated protein kinase
-
6
المؤلفون: Erich Hoffmann, John Franks, Robert G. Webster, Hui-Ling Yen, Stephan Pleschka, Henju Marjuki
المصدر: Virology Journal
Virology Journal, Vol 4, Iss 1, p 134 (2007)مصطلحات موضوعية: MAPK/ERK pathway, viruses, MAPK cascade, medicine.disease_cause, Virus Replication, Influenza A Virus, H1N1 Subtype, Influenza A virus, Extracellular Signal-Regulated MAP Kinases, Polymerase, Ribonucleoprotein, 0303 health sciences, Ribonucleoproteins - Metabolism, biology, virus diseases, Influenza, Human - Enzymology - Virology, MAP Kinase Kinase Kinases, 3. Good health, Infectious Diseases, Hemagglutinins, Ribonucleoproteins, Map Kinase Signaling System - Physiology, raf Kinases, Influenza A Virus, H3n2 Subtype - Enzymology - Metabolism - Physiology, Extracellular Signal-Regulated Map Kinases - Metabolism, Viral Proteins - Metabolism, MAP Kinase Signaling System, Hemagglutinins - Metabolism, Virus, lcsh:Infectious and parasitic diseases, 03 medical and health sciences, Viral Proteins, Dogs, Virology, Influenza, Human, medicine, Animals, Humans, lcsh:RC109-216, Map Kinase Kinase Kinases - Metabolism, 030304 developmental biology, Raf Kinases - Metabolism, 030306 microbiology, Influenza A Virus, H3N2 Subtype, Research, Rna Replicase - Metabolism, RNA-Dependent RNA Polymerase, Molecular biology, Nucleoprotein, respiratory tract diseases, Enzyme Activation, Viral replication, Influenza A Virus, H1n1 Subtype - Enzymology - Metabolism - Physiology, biology.protein
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::780439efbc0cffff2c6f5a4ab9bba301
https://pubmed.ncbi.nlm.nih.gov/18053252
