المؤلفون: Park SO; Department of Plastic and Reconstructive Surgery, Hanyang University College of Medicine, Seoul, Korea., Wang HW; Department of Plastic and Reconstructive Surgery, Hanyang University College of Medicine, Seoul, Korea., Han Y; Department of Medicine, Hanyang University College of Medicine, Seoul, Korea., Ahn HC; Department of Plastic and Reconstructive Surgery, CHA University Bundang Medical Center, Seongnam-si, Gyeonggi-do, Korea.

المصدر: Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2024 Aug 01; Vol. 63 (8), pp. 2123-2127.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 100883501 Publication Model: Print Cited Medium: Internet ISSN: 1462-0332 (Electronic) Linking ISSN: 14620324 NLM ISO Abbreviation: Rheumatology (Oxford) Subsets: MEDLINE

مواضيع طبية MeSH: Raynaud Disease*/surgery , Raynaud Disease*/etiology , Fingers*/blood supply , Fingers*/surgery, Humans ; Female ; Male ; Middle Aged ; Retrospective Studies ; Adult ; Aged ; Treatment Outcome ; Recurrence ; Veins/transplantation ; Ischemia/surgery ; Ischemia/etiology ; Plastic Surgery Procedures/methods ; Kaplan-Meier Estimate ; Arteries/transplantation ; Risk Factors ; Proportional Hazards Models

المؤلفون: Virgili-Gervais G; Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, Canada., Matthews B; Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, Canada., Nassar EL; Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, Canada; Department of Psychiatry, McGill University, Montreal, QC, Canada., Carrier ME; Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, Canada., Kwakkenbos L; Department of Clinical Psychology, Behavioural Science Institute, Radboud University, Nijmegen, Netherlands; Department of IQ Health, Radboud University Medical Center, Nijmegen, Netherlands; Centre for Mindfulness, Department of Psychiatry, Radboud University Medical Center, Nijmegen, Netherlands., Pauling JD; Department of Rheumatology, North Bristol NHS Trust, Bristol, UK; Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Bartlett SJ; Department of Medicine, McGill University, Montreal, QC, Canada; Research Institute, McGill University Health Centre, Montreal, QC, Canada; Arthritis Research Canada, Vancouver, BC, Canada., Gietzen A; National Scleroderma Foundation, Tri-State Chapter, Buffalo, NY, USA., Gottesman K; National Scleroderma Foundation, Los Angeles, CA, USA., Guillot G; Sclérodermie Québec, Longueuil, QC, Canada., Hudson M; Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, Canada; Department of Medicine, McGill University, Montreal, QC, Canada., Hummers LK; Johns Hopkins University School of Medicine, Division of Rheumatology, Baltimore, MD, USA., Lawrie-Jones A; Scleroderma Australia, Melbourne, VIC, Australia; Scleroderma Victoria, Melbourne, VIC, Australia., Malcarne VL; Department of Psychology, San Diego State University, San Diego, CA, USA; San Diego State University-University of California, San Diego Joint Doctoral Program in Clinical Psychology, San Diego, CA, USA., Mayes MD; University of Texas McGovern School of Medicine, Houston, TX, USA., Richard M; Scleroderma Atlantic, Halifax, NS, Canada., Sauvé M; Scleroderma Society of Ontario, Hamilton, ON, Canada; Scleroderma Canada, Hamilton, ON, Canada., Wojeck RK; University of Rhode Island, Kingston, RI, USA., Mouthon L; Service de Médecine Interne, Centre de Référence Maladies Autoimmunes et Autoinflammatoires Systémiques Rares d'Ile de France, de l'Est et de l'Ouest, Hôpital Cochin, Paris, France; Assistance Publique Hôpitaux de Paris-Centre, Université Paris Cité, Paris, France., Benedetti A; Department of Medicine, McGill University, Montreal, QC, Canada; Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada; Research Institute, McGill University Health Centre, Montreal, QC, Canada; Respiratory Epidemiology and Clinical Research Unit, McGill University Health Centre, Montreal, QC, Canada., Thombs BD; Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, Canada; Department of Psychiatry, McGill University, Montreal, QC, Canada; Department of Medicine, McGill University, Montreal, QC, Canada; Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada; Biomedical Ethics Unit, McGill University, Montreal, QC, Canada; Department of Psychology, McGill University, Montreal, QC, Canada. Electronic address: brett.thombs@mcgill.ca.

مؤلفون مشاركون: Scleroderma Patient-centered Intervention Network investigators

المصدر: The Lancet. Rheumatology [Lancet Rheumatol] 2024 Oct; Vol. 6 (10), pp. e684-e692. Date of Electronic Publication: 2024 Aug 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101765308 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2665-9913 (Electronic) Linking ISSN: 26659913 NLM ISO Abbreviation: Lancet Rheumatol Subsets: MEDLINE

مواضيع طبية MeSH: Raynaud Disease*/epidemiology , Raynaud Disease*/etiology , Scleroderma, Systemic*/complications , Severity of Illness Index* , Self Report*, Humans ; Female ; Male ; Middle Aged ; Adult ; Temperature ; Aged ; Cohort Studies ; Seasons

المؤلفون: Cutolo M; Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, 16132 Genoa, Italy; University of Genova, 16132 Genoa, Italy; IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy. Electronic address: mcutolo@unige.it., Smith V; Department of Internal Medicine, Ghent University, Ghent, Belgium; Department of Rheumatology, Ghent University Hospital, Ghent, Belgium; Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Center, Technologiepark-Zwijnaarde, Ghent, Belgium., Hysa E; Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, 16132 Genoa, Italy; Department of Experimental Medicine, University of Genova, 16132 Genoa, Italy; University of Genova, 16132 Genoa, Italy.

المصدر: The Lancet. Rheumatology [Lancet Rheumatol] 2024 Oct; Vol. 6 (10), pp. e655-e657. Date of Electronic Publication: 2024 Aug 28.

نوع المنشور: Letter; Journal Article

بيانات الدورية: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101765308 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2665-9913 (Electronic) Linking ISSN: 26659913 NLM ISO Abbreviation: Lancet Rheumatol Subsets: MEDLINE

مواضيع طبية MeSH: Raynaud Disease*/diagnosis , Raynaud Disease*/etiology , Scleroderma, Systemic*/complications, Humans ; Temperature ; Female ; Middle Aged ; Male

عنوان ترانسليتريتد: Fenómeno de Raynaud en el pezón durante la lactancia: serie de casos.

المؤلفون: Eymann A; Department of Clinical Pediatrics; Hospital Italiano de Buenos Aires, City of Buenos Aires, Argentina., Pontoriero Daroni J; Department of Clinical Pediatrics; Hospital Italiano de Buenos Aires, City of Buenos Aires, Argentina., Brinci M; Department of Neonatology; Hospital Italiano de Buenos Aires, City of Buenos Aires, Argentina., Cámera S; Department of General Medicine; Hospital Italiano de Buenos Aires, City of Buenos Aires, Argentina.

المصدر: Archivos argentinos de pediatria [Arch Argent Pediatr] 2024 Oct 01; Vol. 122 (5), pp. e202310280. Date of Electronic Publication: 2024 May 23.

نوع المنشور: Case Reports; Journal Article

بيانات الدورية: Publisher: Sociedad Argentina de Pediatría Country of Publication: Argentina NLM ID: 0372460 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1668-3501 (Electronic) Linking ISSN: 03250075 NLM ISO Abbreviation: Arch Argent Pediatr Subsets: MEDLINE

مواضيع طبية MeSH: Breast Feeding* , Raynaud Disease*/etiology , Raynaud Disease*/diagnosis , Nipples*/blood supply, Humans ; Female ; Adult ; Young Adult ; Retrospective Studies ; Time Factors

المؤلفون: Tervi A; Institute for Molecular Medicine Finland, FIMM, Helsinki Institute of Life Science - HiLIFE, University of Helsinki, Helsinki, Finland. Electronic address: anniina.tervi@helsinki.fi., Ramste M; Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA., Abner E; Institute of Genomics, University of Tartu, Tartu, Estonia., Cheng P; Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA., Lane JM; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Maher M; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Valliere J; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Lammi V; Institute for Molecular Medicine Finland, FIMM, Helsinki Institute of Life Science - HiLIFE, University of Helsinki, Helsinki, Finland., Strausz S; Institute for Molecular Medicine Finland, FIMM, Helsinki Institute of Life Science - HiLIFE, University of Helsinki, Helsinki, Finland., Riikonen J; Institute for Molecular Medicine Finland, FIMM, Helsinki Institute of Life Science - HiLIFE, University of Helsinki, Helsinki, Finland., Nguyen T; Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA., Martyn GE; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA; Basic Science and Engineering Initiative, Stanford Children's Health, Betty Irene Moore Children's Heart Center, Stanford, CA, USA., Sheth MU; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA; Basic Science and Engineering Initiative, Stanford Children's Health, Betty Irene Moore Children's Heart Center, Stanford, CA, USA., Xia F; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA; Basic Science and Engineering Initiative, Stanford Children's Health, Betty Irene Moore Children's Heart Center, Stanford, CA, USA., Docampo ML; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA; Stanford Children's Health Betty Irene Moore Children's Heart Center, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA., Gu W; Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA., Esko T; Institute of Genomics, University of Tartu, Tartu, Estonia., Saxena R; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Pirinen M; Institute for Molecular Medicine Finland, FIMM, Helsinki Institute of Life Science - HiLIFE, University of Helsinki, Helsinki, Finland; Department of Mathematics and Statistics, University of Helsinki, Helsinki, Finland; Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Palotie A; Institute for Molecular Medicine Finland, FIMM, Helsinki Institute of Life Science - HiLIFE, University of Helsinki, Helsinki, Finland; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ripatti S; Institute for Molecular Medicine Finland, FIMM, Helsinki Institute of Life Science - HiLIFE, University of Helsinki, Helsinki, Finland; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Sinnott-Armstrong N; Herbold Computational Biology Program, Public Health Sciences Division, Fred Hutch, Seattle, WA, USA., Daly M; Institute for Molecular Medicine Finland, FIMM, Helsinki Institute of Life Science - HiLIFE, University of Helsinki, Helsinki, Finland; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Engreitz JM; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA; Basic Science and Engineering Initiative, Stanford Children's Health, Betty Irene Moore Children's Heart Center, Stanford, CA, USA; The Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute of MIT and Harvard, Cambridge, MA, USA; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA., Rabinovitch M; Stanford Children's Health Betty Irene Moore Children's Heart Center, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA., Heckman CA; Institute for Molecular Medicine Finland, FIMM, Helsinki Institute of Life Science - HiLIFE, University of Helsinki, Helsinki, Finland., Quertermous T; Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA., Jones SE; Institute for Molecular Medicine Finland, FIMM, Helsinki Institute of Life Science - HiLIFE, University of Helsinki, Helsinki, Finland., Ollila HM; Institute for Molecular Medicine Finland, FIMM, Helsinki Institute of Life Science - HiLIFE, University of Helsinki, Helsinki, Finland; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. Electronic address: hanna.m.ollila@helsinki.fi.

مؤلفون مشاركون: FinnGen, Estonian Biobank research team

المصدر: Cell genomics [Cell Genom] 2024 Sep 11; Vol. 4 (9), pp. 100630. Date of Electronic Publication: 2024 Aug 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 9918284260106676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-979X (Electronic) Linking ISSN: 2666979X NLM ISO Abbreviation: Cell Genom Subsets: MEDLINE

مواضيع طبية MeSH: Raynaud Disease*/genetics , Raynaud Disease*/immunology , Quantitative Trait Loci* , Genome-Wide Association Study*, Humans ; Nitric Oxide Synthase Type III/genetics ; Nitric Oxide Synthase Type III/metabolism ; Female ; Male

المؤلفون: Schonenberg-Meinema D; Department of Pediatric Immunology, Rheumatology and Infectious Diseases, Emma Children's Hospital, Amsterdam University Medical Centers, University of Amsterdam, the Netherlands. Electronic address: d.schonenberg@amsterdamumc.nl., Cutolo M; Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS Polyclinic San Martino Hospital, Genova, Italy., Smith V; Department of Rheumatology, Ghent University Hospital, Belgium; Faculty of Internal Medicine, Ghent University, Ghent, Belgium; Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Center (IRC), Ghent, Belgium.

المصدر: Best practice & research. Clinical rheumatology [Best Pract Res Clin Rheumatol] 2024 Sep; Vol. 38 (3), pp. 101978. Date of Electronic Publication: 2024 Jul 20.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101121149 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1770 (Electronic) Linking ISSN: 15216942 NLM ISO Abbreviation: Best Pract Res Clin Rheumatol Subsets: MEDLINE

مواضيع طبية MeSH: Microscopic Angioscopy*/methods , Raynaud Disease*/diagnosis , Raynaud Disease*/physiopathology , Raynaud Disease*/diagnostic imaging , Dermatomyositis*/diagnostic imaging , Dermatomyositis*/diagnosis , Dermatomyositis*/physiopathology , Lupus Erythematosus, Systemic*/diagnostic imaging , Scleroderma, Systemic*/diagnostic imaging , Scleroderma, Systemic*/physiopathology, Humans ; Child ; Capillaries/diagnostic imaging ; Rheumatology/methods ; Rheumatologists ; Nails/blood supply ; Nails/diagnostic imaging ; Mixed Connective Tissue Disease/diagnostic imaging ; Scleroderma, Localized

SCR Disease Name: Juvenile systemic scleroderma; Juvenile-onset scleroderma

المؤلفون: Di Battista M; M. Di Battista, MD, Rheumatology Unit, University of Pisa, Pisa, and Department of Medical Biotechnologies, University of Siena, Siena; dibattista.marco91@gmail.com., Della Rossa A; A. Della Rossa, MD, PhD, M. Mosca, MD, PhD, Rheumatology Unit, University of Pisa, Pisa, Italy., Mosca M; A. Della Rossa, MD, PhD, M. Mosca, MD, PhD, Rheumatology Unit, University of Pisa, Pisa, Italy.

المصدر: The Journal of rheumatology [J Rheumatol] 2024 Sep 01; Vol. 51 (9), pp. 899-903. Date of Electronic Publication: 2024 Sep 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Journal Of Rheumatology Publishing Co Country of Publication: Canada NLM ID: 7501984 Publication Model: Electronic Cited Medium: Internet ISSN: 1499-2752 (Electronic) Linking ISSN: 0315162X NLM ISO Abbreviation: J Rheumatol Subsets: MEDLINE

مواضيع طبية MeSH: Scleroderma, Systemic*/drug therapy , Scleroderma, Systemic*/complications , Raynaud Disease*/drug therapy , Raynaud Disease*/etiology , Fingers*/blood supply , Acetamides*/therapeutic use , Acetamides*/adverse effects , Pyrazines*/therapeutic use , Pyrazines*/adverse effects, Humans ; Female ; Male ; Middle Aged ; Treatment Outcome ; Adult ; Aged ; Skin Ulcer/etiology ; Skin Ulcer/drug therapy ; Microscopic Angioscopy/methods

المؤلفون: Boland C; Consultant Psychiatrist, Cork, Ireland. cailin.boland@gmail.com., Adams E; Consultant Psychiatrist, Mid-East Kildare Mental Health Services, Kildare, Ireland., Wong MC; Consultant Psychiatrist, Finglas CMHT, CHO9, Dublin, Ireland., Denihan C; Consultant Psychiatrist, Dublin, Ireland.

المصدر: BMC psychiatry [BMC Psychiatry] 2024 Aug 28; Vol. 24 (1), pp. 586. Date of Electronic Publication: 2024 Aug 28.

نوع المنشور: Case Reports; Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100968559 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-244X (Electronic) Linking ISSN: 1471244X NLM ISO Abbreviation: BMC Psychiatry Subsets: MEDLINE

مواضيع طبية MeSH: Lithium Carbonate*/administration & dosage , Lithium Carbonate*/adverse effects , Raynaud Disease*/chemically induced, Humans ; Male ; Antimanic Agents/administration & dosage ; Antimanic Agents/adverse effects ; Depressive Disorder, Treatment-Resistant/drug therapy

المؤلفون: Tekavec E; Division of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, 221 00, Lund, Sweden. eva.tekavec@med.lu.se., Nilsson T; Division of Sustainable Health and Medicine, Department of Public Health and Clinical Medicine, Umeå University, 901 87, Umeå, Sweden., Dahlin LB; Department of Translational Medicine - Hand Surgery, Lund University, 221 00, Lund, Sweden., Huynh E; Department of Occupational and Environmental Medicine, Region Skåne, 223 63, Lund, Sweden., Nordander C; Division of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, 221 00, Lund, Sweden., Riddar J; Division of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, 221 00, Lund, Sweden., Kåredal M; Division of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, 221 00, Lund, Sweden.; Department of Occupational and Environmental Medicine, Region Skåne, 223 63, Lund, Sweden.

المصدر: Scientific reports [Sci Rep] 2024 Aug 05; Vol. 14 (1), pp. 18128. Date of Electronic Publication: 2024 Aug 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Raynaud Disease*/blood , Raynaud Disease*/diagnosis , Biomarkers*/blood , Vibration*/adverse effects , Hand-Arm Vibration Syndrome*/blood , Hand-Arm Vibration Syndrome*/diagnosis, Humans ; Male ; Female ; Middle Aged ; Adult ; Severity of Illness Index ; von Willebrand Factor/metabolism ; von Willebrand Factor/analysis ; Calcitonin Gene-Related Peptide/blood ; Aged

المؤلفون: Piera-Velazquez S; Jefferson Institute of Molecular Medicine and Scleroderma Center, Thomas Jefferson University, Philadelphia, PA, USA., Fortina P; Cancer Genomics and Bioinformatics Laboratory, Department of Pharmacology, Physiology, and Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA., Jimenez SA; Jefferson Institute of Molecular Medicine and Scleroderma Center, Thomas Jefferson University, Philadelphia, PA, USA. sergio.jimenez@jefferson.edu.

المصدر: Clinical and experimental rheumatology [Clin Exp Rheumatol] 2024 Aug; Vol. 42 (8), pp. 1629-1634. Date of Electronic Publication: 2024 Aug 01.

نوع المنشور: Journal Article; Comparative Study

بيانات الدورية: Publisher: Clinical And Experimental Rheumatology S.A.S Country of Publication: Italy NLM ID: 8308521 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0392-856X (Print) Linking ISSN: 0392856X NLM ISO Abbreviation: Clin Exp Rheumatol Subsets: MEDLINE

مواضيع طبية MeSH: Raynaud Disease*/blood , Raynaud Disease*/genetics , Raynaud Disease*/immunology , Raynaud Disease*/diagnosis , Antibodies, Antinuclear*/blood , Exosomes*/genetics , MicroRNAs*/blood , MicroRNAs*/genetics, Humans ; Female ; Middle Aged ; Male ; Adult ; Biomarkers/blood ; High-Throughput Nucleotide Sequencing ; Circulating MicroRNA/blood ; Circulating MicroRNA/genetics ; Aged ; Predictive Value of Tests