المؤلفون: Cris Kamperschroer, Jacintha Shenton, Hervé Lebrec, John K. Leighton, Paul A. Moore, Oliver Thomas

المصدر: Journal of Immunotoxicology, Vol 17, Iss 1, Pp 67-85 (2020)

مصطلحات موضوعية: cd3 bispecific, redirected t-cell therapy, nonclinical safety, toxicity, cynomolgus monkey, clinical safety management, cytokine release, clinical starting dose, first-in-human dose, fda, Immunologic diseases. Allergy, RC581-607, Toxicology. Poisons, RA1190-1270

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1547-691X; https://doaj.org/toc/1547-6901

URL الوصول: https://doaj.org/article/9b9d19fabbc749bc85340c7759626998

المؤلفون: John Leighton, Jacintha Shenton, Paul A Moore, Oliver Thomas, Herve Lebrec, Cris Kamperschroer

المصدر: Journal of Immunotoxicology, Vol 17, Iss 1, Pp 67-85 (2020)

مصطلحات موضوعية: clinical starting dose, first-in-human dose, CD3 Complex, Consensus Development Conferences as Topic, T-Lymphocytes, Normal tissue, 010501 environmental sciences, Toxicology, 01 natural sciences, Translational Research, Biomedical, Japan, Neoplasms, Antibodies, Bispecific, 0303 health sciences, Europe, Cytokine release syndrome, nonclinical safety, cytokine release, Cytokines, Regulatory agency, Cytokine Release Syndrome, lcsh:Immunologic diseases. Allergy, redirected t-cell therapy, medicine.medical_specialty, Consensus, Immunology, Receptors, Antigen, T-Cell, Antineoplastic Agents, Food and drug administration, 03 medical and health sciences, Therapeutic index, lcsh:RA1190-1270, Antigens, Neoplasm, medicine, Animals, Humans, Intensive care medicine, Management practices, fda, lcsh:Toxicology. Poisons, 030304 developmental biology, 0105 earth and related environmental sciences, United States Food and Drug Administration, business.industry, Binding properties, toxicity, medicine.disease, United States, cynomolgus monkey, clinical safety management, Drug Screening Assays, Antitumor, lcsh:RC581-607, business, cd3 bispecific, Target organ

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce2ee2c651440cfde51cdc8de8d46cba
https://doi.org/10.1080/1547691x.2020.1729902

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