المؤلفون: Yaara Zwang, Oliver Jonas, Casandra Chen, Mikael L Rinne, John G Doench, Federica Piccioni, Li Tan, Hai-Tsang Huang, Jinhua Wang, Young Jin Ham, Joyce O'Connell, Patrick Bhola, Mihir Doshi, Matthew Whitman, Michael Cima, Anthony Letai, David E Root, Robert S Langer, Nathanael Gray, William C Hahn

المصدر: eLife, Vol 6 (2017)

مصطلحات موضوعية: PI3K inhibition, genome-scale shRNA screen, response modifying genes, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/24523; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/e53a69f812244f4b946e1569b458a6f8

المؤلفون: Matthew Whitman, Joyce T. O’Connell, Mihir B. Doshi, Patrick Bhola, Li Tan, Jinhua Wang, Robert Langer, Anthony Letai, Oliver Jonas, Young Jin Ham, John G. Doench, Yaara Zwang, William C. Hahn, Casandra Chen, David E. Root, Nathanael S. Gray, Federica Piccioni, Mikael L. Rinne, Hai-Tsang Huang, Michael J. Cima

المساهمون: Massachusetts Institute of Technology. Department of Chemical Engineering, Massachusetts Institute of Technology. Department of Materials Science and Engineering, Koch Institute for Integrative Cancer Research at MIT, Jonas, Oliver H., Cima, Michael J, Langer, Robert S

المصدر: eLife
eLife, Vol 6 (2017)

مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Cell cycle checkpoint, PI3K inhibition, QH301-705.5, Cell Survival, Science, Transplantation, Heterologous, Apoptosis, Mice, SCID, Pharmacology, Biology, Protein Serine-Threonine Kinases, General Biochemistry, Genetics and Molecular Biology, Small hairpin RNA, 03 medical and health sciences, Cell Line, Tumor, Proto-Oncogene Proteins, Animals, Humans, genome-scale shRNA screen, Biology (General), Enzyme Inhibitors, PI3K/AKT/mTOR pathway, Cell Proliferation, Phosphoinositide-3 Kinase Inhibitors, Cancer Biology, response modifying genes, General Immunology and Microbiology, Cell growth, Kinase, General Neuroscience, Drug Synergism, General Medicine, Neoplasms, Experimental, Suicide gene, MAP Kinase Kinase Kinases, 3. Good health, Disease Models, Animal, 030104 developmental biology, Treatment Outcome, Cancer cell, Cancer research, Medicine, Protein Kinases, Research Article, Human

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e07b87becfcb9ec1d6ccbefccac8786
https://pubmed.ncbi.nlm.nih.gov/28561737

المؤلفون: Zwang, Yaara, Jonas, Oliver, Chen, Casandra, Rinne, Mikael L, Doench, John G, Piccioni, Federica, Tan, Li, Huang, Hai-Tsang, Wang, Jinhua, Ham, Young Jin, O'Connell, Joyce, Bhola, Patrick, Doshi, Mihir, Whitman, Matthew, Cima, Michael, Letai, Anthony, Root, David E, Langer, Robert S, Gray, Nathanael, Hahn, William C

المصدر: Zwang, Y., O. Jonas, C. Chen, M. L. Rinne, J. G. Doench, F. Piccioni, L. Tan, et al. 2017. “Synergistic interactions with PI3K inhibition that induce apoptosis.” eLife 6 (1): e24523. doi:10.7554/eLife.24523. http://dx.doi.org/10.7554/eLife.24523.

مصطلحات موضوعية: PI3K inhibition, genome-scale shRNA screen, response modifying genes, Human

Relation: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479695/pdf/; eLife

URL الوصول: http://nrs.harvard.edu/urn-3:HUL.InstRepos:33490894