المؤلفون: Khizer H; National Center for Bioinformatics, Quaid-i-Azam University, Islamabad, Pakistan., Maryam A; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, United States., Ansari A; National Center for Bioinformatics, Quaid-i-Azam University, Islamabad, Pakistan., Ahmad MS; School of Chemical Engineering, Hebei University of Technology, Tianjin, 300401, PR China., Khalid RR; National Center for Bioinformatics, Quaid-i-Azam University, Islamabad, Pakistan. Electronic address: ray.binm@gmail.com.

المصدر: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2024 Jun; Vol. 756, pp. 110010. Date of Electronic Publication: 2024 Apr 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0372430 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0384 (Electronic) Linking ISSN: 00039861 NLM ISO Abbreviation: Arch Biochem Biophys Subsets: MEDLINE

مواضيع طبية MeSH: Molecular Dynamics Simulation* , Poly (ADP-Ribose) Polymerase-1*/metabolism , Poly (ADP-Ribose) Polymerase-1*/antagonists & inhibitors , Poly (ADP-Ribose) Polymerase-1*/chemistry , Poly(ADP-ribose) Polymerase Inhibitors*/chemistry , Poly(ADP-ribose) Polymerase Inhibitors*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/pharmacology , Drug Design*, Humans ; Molecular Docking Simulation ; Catalytic Domain ; Poly(ADP-ribose) Polymerases/metabolism ; Poly(ADP-ribose) Polymerases/chemistry ; Hydrogen Bonding

المؤلفون: Gopal AA; Institute for Innovation in Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114., Fernandez B; Institute for Innovation in Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114., Delano J; Institute for Innovation in Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114., Weissleder R; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114; Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114; Department of Systems Biology, Harvard Medical School, Boston, MA 02115., Dubach JM; Institute for Innovation in Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114; Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114. Electronic address: dubach.matt@mgh.harvard.edu.

المصدر: Cell chemical biology [Cell Chem Biol] 2024 Jul 18; Vol. 31 (7), pp. 1373-1382.e10. Date of Electronic Publication: 2024 Jan 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Poly(ADP-ribose) Polymerase Inhibitors*/pharmacology , Poly(ADP-ribose) Polymerase Inhibitors*/chemistry, Humans ; Kinetics ; Poly (ADP-Ribose) Polymerase-1/metabolism ; Poly (ADP-Ribose) Polymerase-1/antagonists & inhibitors ; DNA Damage/drug effects ; Poly(ADP-ribose) Polymerases/metabolism ; Poly(ADP-ribose) Polymerases/chemistry ; DNA/metabolism ; DNA/chemistry

المؤلفون: Vekariya U; Fels Cancer Institute for Personalized Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA., Minakhin L; Thomas Jefferson University, Sidney Kimmel Cancer Center, Department of Biochemistry and Molecular Biology, Philadelphia, PA, 19107, USA., Chandramouly G; Thomas Jefferson University, Sidney Kimmel Cancer Center, Department of Biochemistry and Molecular Biology, Philadelphia, PA, 19107, USA., Tyagi M; Thomas Jefferson University, Sidney Kimmel Cancer Center, Department of Biochemistry and Molecular Biology, Philadelphia, PA, 19107, USA., Kent T; Thomas Jefferson University, Sidney Kimmel Cancer Center, Department of Biochemistry and Molecular Biology, Philadelphia, PA, 19107, USA., Sullivan-Reed K; Fels Cancer Institute for Personalized Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA., Atkins J; Fels Cancer Institute for Personalized Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA., Ralph D; Thomas Jefferson University, Sidney Kimmel Cancer Center, Department of Biochemistry and Molecular Biology, Philadelphia, PA, 19107, USA., Nieborowska-Skorska M; Fels Cancer Institute for Personalized Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA., Kukuyan AM; Fels Cancer Institute for Personalized Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA., Tang HY; Proteomics and Metabolomics Facility, The Wistar Institute, Philadelphia, PA, 19104, USA., Pomerantz RT; Thomas Jefferson University, Sidney Kimmel Cancer Center, Department of Biochemistry and Molecular Biology, Philadelphia, PA, 19107, USA. richard.pomerantz@jefferson.edu., Skorski T; Fels Cancer Institute for Personalized Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA. tskorski@temple.edu.; Department of Cancer and Cellular Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA. tskorski@temple.edu.; Nuclear Dynamics and Cancer Program, Fox Chase Cancer Center, Philadelphia, PA, USA. tskorski@temple.edu.

المصدر: Nature communications [Nat Commun] 2024 Jul 11; Vol. 15 (1), pp. 5822. Date of Electronic Publication: 2024 Jul 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Poly (ADP-Ribose) Polymerase-1*/metabolism , Poly (ADP-Ribose) Polymerase-1*/genetics , DNA Polymerase theta* , DNA End-Joining Repair* , DNA-Directed DNA Polymerase*/metabolism , DNA Breaks, Double-Stranded*, Humans ; Poly Adenosine Diphosphate Ribose/metabolism ; DNA Damage ; Animals ; DNA-Binding Proteins/metabolism ; DNA-Binding Proteins/genetics ; DNA/metabolism ; DNA/genetics ; HEK293 Cells ; Poly ADP Ribosylation ; Poly(ADP-ribose) Polymerases/metabolism ; Poly(ADP-ribose) Polymerases/genetics ; Carrier Proteins ; Glycoside Hydrolases ; Nuclear Proteins

المؤلفون: Zentout S; University of Rennes, CNRS, Institut de génétique et développement de Rennes-UMR 6290, Biologie, Santé, Innovation Technologique (BIOSIT)-UMS3480, Rennes F-35000, France., Imburchia V; University of Rennes, CNRS, Institut de génétique et développement de Rennes-UMR 6290, Biologie, Santé, Innovation Technologique (BIOSIT)-UMS3480, Rennes F-35000, France., Chapuis C; University of Rennes, CNRS, Institut de génétique et développement de Rennes-UMR 6290, Biologie, Santé, Innovation Technologique (BIOSIT)-UMS3480, Rennes F-35000, France., Duma L; Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom., Schützenhofer K; Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom., Prokhorova E; Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom., Ahel I; Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom., Smith R; University of Rennes, CNRS, Institut de génétique et développement de Rennes-UMR 6290, Biologie, Santé, Innovation Technologique (BIOSIT)-UMS3480, Rennes F-35000, France.; Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom., Huet S; University of Rennes, CNRS, Institut de génétique et développement de Rennes-UMR 6290, Biologie, Santé, Innovation Technologique (BIOSIT)-UMS3480, Rennes F-35000, France.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Jun 18; Vol. 121 (25), pp. e2322689121. Date of Electronic Publication: 2024 Jun 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Poly(ADP-ribose) Polymerase Inhibitors*/pharmacology , Poly (ADP-Ribose) Polymerase-1*/metabolism , Poly (ADP-Ribose) Polymerase-1*/genetics , Poly (ADP-Ribose) Polymerase-1*/antagonists & inhibitors , ADP-Ribosylation* , Histones*/metabolism, Humans ; DNA Damage ; Drug Resistance, Neoplasm/genetics ; Cell Line, Tumor ; Poly(ADP-ribose) Polymerases/metabolism ; Poly(ADP-ribose) Polymerases/genetics

المؤلفون: Kelly M; Division of Biochemistry, Department of Chemistry, University of Cincinnati, 301 Clifton Ct, Cincinnati, OH, 45221, USA., Dietz C; Division of Biochemistry, Department of Chemistry, University of Cincinnati, 301 Clifton Ct, Cincinnati, OH, 45221, USA., Kasson S; Division of Biochemistry, Department of Chemistry, University of Cincinnati, 301 Clifton Ct, Cincinnati, OH, 45221, USA., Zhang Y; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO, 63110, USA., Holtzman MJ; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO, 63110, USA., Kim IK; Division of Biochemistry, Department of Chemistry, University of Cincinnati, 301 Clifton Ct, Cincinnati, OH, 45221, USA. Electronic address: kimiw@ucmail.uc.edu.

المصدر: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Aug 06; Vol. 720, pp. 150101. Date of Electronic Publication: 2024 May 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

مواضيع طبية MeSH: Ubiquitin-Protein Ligases*/metabolism , Ubiquitination* , Adenosine Diphosphate Ribose*/metabolism, Humans ; Poly ADP Ribosylation ; Poly Adenosine Diphosphate Ribose/metabolism ; Poly(ADP-ribose) Polymerases/metabolism ; Poly(ADP-ribose) Polymerases/chemistry ; Poly(ADP-ribose) Polymerases/genetics ; Ubiquitin/metabolism ; ADP-Ribosylation ; HEK293 Cells

المؤلفون: Zhang H; Institute for Cancer Genetics, Vagelos College for Physicians and Surgeons, Columbia University, New York City, NY 10032, USA., Zha S; Institute for Cancer Genetics, Vagelos College for Physicians and Surgeons, Columbia University, New York City, NY 10032, USA; Department of Pathology and Cell Biology, Herbert Irvine Comprehensive Cancer Center, Vagelos College for Physicians and Surgeons, Columbia University, New York City, NY 10032, USA; Division of Hematology, Oncology and Stem Cell Transplantation, Department of Pediatrics, Vagelos College for Physicians and Surgeons, Columbia University, New York City, NY 10032, USA; Department of Immunology and Microbiology, Vagelos College for Physicians and Surgeons, Columbia University, New York City, NY 10032, USA. Electronic address: sz2296@cumc.columbia.edu.

المصدر: DNA repair [DNA Repair (Amst)] 2024 Aug; Vol. 140, pp. 103690. Date of Electronic Publication: 2024 May 25.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101139138 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1568-7856 (Electronic) Linking ISSN: 15687856 NLM ISO Abbreviation: DNA Repair (Amst) Subsets: MEDLINE

مواضيع طبية MeSH: DNA Replication* , Poly(ADP-ribose) Polymerases*/metabolism , DNA Damage* , DNA Repair* , Poly (ADP-Ribose) Polymerase-1*/metabolism, Humans ; Animals ; Poly(ADP-ribose) Polymerase Inhibitors/pharmacology

المؤلفون: Kolesnichenko M; Department of Hepatology and Gastroenterology, Charité-Universitätsmedizin Berlin, Berlin, Germany. marina.kolesnichenko@charite.de., Scheidereit C; Laboratory for Signal Transduction in Tumor Cells, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany. scheidereit@mdc-berlin.de.

المصدر: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2024 Jul 29; Vol. 9 (1), pp. 179. Date of Electronic Publication: 2024 Jul 29.

نوع المنشور: Letter; Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE

مواضيع طبية MeSH: Poly(ADP-ribose) Polymerase Inhibitors*/pharmacology , Poly(ADP-ribose) Polymerase Inhibitors*/therapeutic use , Synthetic Lethal Mutations*/genetics, Humans ; Transcription, Genetic/drug effects ; DNA Replication/drug effects ; DNA Replication/genetics ; Poly(ADP-ribose) Polymerases/genetics ; Poly(ADP-ribose) Polymerases/metabolism

المؤلفون: Fröhlich LM; Department of Dermatology, Division of Dermatooncology, University of Tübingen, Tübingen, Germany., Villar-Miyar A; Department of Dermatology, Division of Dermatooncology, University of Tübingen, Tübingen, Germany., Heintze T; Department of Dermatology, Division of Dermatooncology, University of Tübingen, Tübingen, Germany., Sauer B; Department of Dermatology, Division of Dermatooncology, University of Tübingen, Tübingen, Germany., Schittek B; Department of Dermatology, Division of Dermatooncology, University of Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', University of Tübingen, Tübingen, Germany.

المصدر: International journal of cancer [Int J Cancer] 2024 Jul 15; Vol. 155 (2), pp. 203-210. Date of Electronic Publication: 2024 Apr 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0042124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0215 (Electronic) Linking ISSN: 00207136 NLM ISO Abbreviation: Int J Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Melanoma*/drug therapy , Melanoma*/mortality , Melanoma*/genetics , Melanoma*/pathology , Melanoma*/metabolism , Poly (ADP-Ribose) Polymerase-1*/metabolism , Poly(ADP-ribose) Polymerase Inhibitors*/therapeutic use , Poly(ADP-ribose) Polymerase Inhibitors*/pharmacology , Skin Neoplasms*/drug therapy , Skin Neoplasms*/mortality , Skin Neoplasms*/pathology , Skin Neoplasms*/genetics , Skin Neoplasms*/metabolism, Female ; Humans ; Male ; Biomarkers, Tumor/metabolism ; Biomarkers, Tumor/genetics ; Cell Line, Tumor ; Drug Resistance, Neoplasm/genetics ; Neoplasm Metastasis ; Poly(ADP-ribose) Polymerases/metabolism ; Prognosis

المؤلفون: Cunningham ML; Department of Urology, Thomas Jefferson University, Philadelphia, Pennsylvania.; Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania., Schiewer MJ; Department of Urology, Thomas Jefferson University, Philadelphia, Pennsylvania.; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, Pennsylvania.; Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.

المصدر: Cancer research [Cancer Res] 2024 Jul 02; Vol. 84 (13), pp. 2049-2059.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Poly(ADP-ribose) Polymerase Inhibitors*/therapeutic use , Poly(ADP-ribose) Polymerase Inhibitors*/pharmacology , Prostatic Neoplasms*/drug therapy , Prostatic Neoplasms*/genetics , Prostatic Neoplasms*/ethnology , Prostatic Neoplasms*/pathology, Humans ; Male ; Clinical Trials as Topic ; Black or African American/genetics ; White People/genetics ; White People/statistics & numerical data ; Poly(ADP-ribose) Polymerases/metabolism ; Poly(ADP-ribose) Polymerases/genetics

المؤلفون: Zhang F; RNA Institute, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, China., Sun J; Department of Hematological Malignancies Translational Science, Gehr Family Center for Leukemia Research, Hematologic Malignancies and Stem Cell Transplantation Institute, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, USA.; Department of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China., Zhang L; Department of Hematological Malignancies Translational Science, Gehr Family Center for Leukemia Research, Hematologic Malignancies and Stem Cell Transplantation Institute, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, USA., Li R; RNA Institute, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, China., Wang Y; RNA Institute, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, China., Geng H; RNA Institute, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, China., Shen C; RNA Institute, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, China., Li L; Department of Hematological Malignancies Translational Science, Gehr Family Center for Leukemia Research, Hematologic Malignancies and Stem Cell Transplantation Institute, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, USA. lingli@coh.org., Chen L; RNA Institute, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, China. liang_chen@whu.edu.cn.

المصدر: British journal of cancer [Br J Cancer] 2024 Jul; Vol. 131 (2), pp. 231-242. Date of Electronic Publication: 2024 May 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1827 (Electronic) Linking ISSN: 00070920 NLM ISO Abbreviation: Br J Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Myelodysplastic Syndromes*/genetics , Myelodysplastic Syndromes*/drug therapy , Myelodysplastic Syndromes*/pathology , Poly(ADP-ribose) Polymerase Inhibitors*/pharmacology , Poly(ADP-ribose) Polymerase Inhibitors*/therapeutic use , Serine-Arginine Splicing Factors*/genetics , Serine-Arginine Splicing Factors*/metabolism , Synthetic Lethal Mutations*, Animals ; Mice ; Humans ; Poly (ADP-Ribose) Polymerase-1/genetics ; Poly (ADP-Ribose) Polymerase-1/antagonists & inhibitors ; Poly (ADP-Ribose) Polymerase-1/metabolism ; Gene Knock-In Techniques ; Mutation ; RNA Splicing