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المؤلفون: Maja Malnar, Angela Bachi, Helena H. Chowdhury, Anemari Horvat, Patrizia D’Adamo, Antonia Gurgone, Saša Trkov Bobnar, Marko Muhič, Lorenzo Piemonti, Maria Lidia Mignogna, Michela Masetti, Jelena Velebit, Veronica Bianchi, Robert Zorec, Matjaž Stenovec, Alessia Mercalli, Katja Fink, Sara Belloli, Stefano Taverna, Maja Potokar, Marko Kreft, Rosa Maria Moresco, Nina Vardjan, Maddalena Ripamonti, Umberto Restuccia
المساهمون: D'Adamo, Patrizia, Horvat, Anemari, Gurgone, Antonia, Mignogna, Maria Lidia, Bianchi, Veronica, Masetti, Michela, Ripamonti, Maddalena, Taverna, Stefano, Velebit, Jelena, Malnar, Maja, Muhič, Marko, Fink, Katja, Bachi, Angela, Restuccia, Umberto, Belloli, Sara, Moresco, Rosa Maria, Mercalli, Alessia, Piemonti, Lorenzo, Potokar, Maja, Bobnar, Saša Trkov, Kreft, Marko, Chowdhury, Helena H, Stenovec, Matjaž, Vardjan, Nina, Zorec, R, D'Adamo, P, Horvat, A, Gurgone, A, Mignogna, M, Bianchi, V, Masetti, M, Ripamonti, M, Taverna, S, Velebit, J, Malnar, M, Muhic, M, Fink, K, Bachi, A, Restuccia, U, Belloli, S, Moresco, R, Mercalli, A, Piemonti, L, Potokar, M, Bobnar, S, Kreft, M, Chowdhury, H, Stenovec, M, Vardjan, N
المصدر: Metabolism
Metabolism, clinical and experimental
116 (2021): 154463. doi:10.1016/j.metabol.2020.154463
info:cnr-pdr/source/autori:D'Adamo P.; Horvat A.; Gurgone A.; Mignogna M.L.; Bianchi V.; Masetti M.; Ripamonti M.; Taverna S.; Velebit J.; Malnar M.; Muhic M.; Fink K.; Bachi A.; Restuccia U.; Belloli S.; Moresco R.M.; Mercalli A.; Piemonti L.; Potokar M.; Bobnar S.T.; Kreft M.; Chowdhury H.H.; Stenovec M.; Vardjan N.; Zorec R./titolo:Inhibiting glycolysis rescues memory impairment in an intellectual disability Gdi1-null mouse/doi:10.1016%2Fj.metabol.2020.154463/rivista:Metabolism, clinical and experimental (Print)/anno:2021/pagina_da:154463/pagina_a:/intervallo_pagine:154463/volume:116مصطلحات موضوعية: 0301 basic medicine, CTX, context memory, Male, Endocrinology, Diabetes and Metabolism, Glucose uptake, Intellectual disability, FRET, Förster Resonance Energy Transfer, SV, synaptic vesicle, XLID, X-linked intellectual disability, Mice, 0302 clinical medicine, Endocrinology, Basic Science, GDI1 knockout mice, Aerobic glycolysis, Astrocytes, cAMP, Glycolysis, Gdi1 KO, full knockout of Gdi1, Cells, Cultured, Guanine Nucleotide Dissociation Inhibitors, NA, noradrenaline, Mice, Knockout, Cultured, 3-Cl-5-OH-BA, 3-chloro-5-hydroxybenzoic acid, Animals, Brain, Deoxyglucose, Down-Regulation, Glucose, Intellectual Disability, Maze Learning, Memory, Memory Disorders, [18F]-FDG, [18F]-fluoro-2-deoxy-d-glucose, Aerobic glycolysi, cAMP, cyclic adenosine monophosphate, GlastGdi1flox/Y, GLAST:CreERT2+/Gdi1lox/Y inducible astrocyte-specific Gdi1 KO male mice, medicine.anatomical_structure, intellectual disability, Knockout mouse, Astrocyte, Gdi1 WT, wild type, medicine.medical_specialty, Cells, Knockout, 030209 endocrinology & metabolism, Biology, 2-DG, 2-deoxy-d-glucose, sEPSCs, spontaneous excitatory postsynaptic currents, CNS, central nervous system, SEM, standard error of the mean, 03 medical and health sciences, αGDI, α guanosine dissociation inhibitor protein coded by GDI1 gene, CFP, cyan fluorescent protein, Downregulation and upregulation, Internal medicine, medicine, aerobic glycolysis, GlastGdi1X/Y, male mice (Gdi1X/Y) carrying the GLAST:CreERT2 transgene, GLUT1, d-glucose transporter, Wild type, astrocytes, GFAP, glial fibrillary acidic protein, PSD, postsynaptic density, GDI1, guanosine dissociation inhibitor 1 gene, YFP, yellow fluorescent protein, 030104 developmental biology, GPCR, G-protein coupled receptor, Anaerobic glycolysis, GPR81, G-protein receptor 81, CS, conditional stimulus, tone, PKA, protein kinase A, MCTs, monocarboxylate transporters, Homeostasis
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المؤلفون: James David Jentsch, Michael Levine, Yao-Ying Ma, Jeff Toll, Christopher J. Evans, Sandy M. Henley, Carlos Cepeda
المصدر: ASN NEURO
ASN Neuro, Vol 5 (2013)
ASN neuro, vol 5, iss 4
Ma, YY; Henley, SM; Toll, J; Jentsch, JD; Evans, CJ; Levine, MS; et al.(2013). Drug-primed reinstatement of cocaine seeking in mice: Increased excitability of medium-sized spiny neurons in the nucleus accumbens. ASN Neuro, 5(4), 257-271. doi: 10.1042/AN20130015. UCLA: Retrieved from: http://www.escholarship.org/uc/item/0gh3n18zمصطلحات موضوعية: nucleus accumbens, AHP, afterhyperpolarization, CsMeth, Cs-Methanesulfonate, KGluc, K-gluconate internal solution, Self Administration, Rin, resistance, Pharmacology, Mice, 0302 clinical medicine, Cocaine, Dopamine Uptake Inhibitors, Postsynaptic potential, Medicine, NAc, nucleus accumbens, Neurons, relapse, 0303 health sciences, General Neuroscience, Substance Abuse, BIC, bicuculline, Depolarization, Coc, cocaine, Hyperpolarization (biology), FR, fixed ratio, S11, mEPSCs, miniature excitatory postsynaptic currents, Administration, Excitatory postsynaptic potential, Administration, Intravenous, Erratum, Self-administration, Intravenous, RMP, resting membrane potential, Research Article, Drug Abuse (NIDA Only), Drug-Seeking Behavior, Nucleus accumbens, Neurotransmission, sEPSCs, spontaneous excitatory postsynaptic currents, lcsh:RC321-571, 03 medical and health sciences, Animals, synaptic transmission, TTX, tetrodotoxin, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, 030304 developmental biology, AL, active lever, IVSA, intravenous self-administration, business.industry, IC, current clamp, MSNs, medium-sized spiny neurons, Neurosciences, VC, voltage clamp, Excitatory Postsynaptic Potentials, Brain Disorders, Thr, threshold, rm, repeated measure, Electrophysiology, Neurology (clinical), business, intravenous self-administration, IAL, inactive lever, GABA, γ-aminobutyric acid, sIPSCs, spontaneous inhibitory postsynaptic currents, 030217 neurology & neurosurgery
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