المؤلفون: Hu Y; Department of Medicinal Chemistry, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, Hunan, China.; Hunan Key Laboratory of Diagnostic and Therapeutic Drug Research for Chronic Diseases, Changsha 410013, Hunan, China.; Hunan Key Laboratory of Organ Fibrosis, Changsha 410013, Hunan, China., Zhao C; Department of Medicinal Chemistry, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, Hunan, China.; Hunan Key Laboratory of Diagnostic and Therapeutic Drug Research for Chronic Diseases, Changsha 410013, Hunan, China.; Hunan Key Laboratory of Organ Fibrosis, Changsha 410013, Hunan, China., Tan W; Department of Medicinal Chemistry, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, Hunan, China.; Hunan Key Laboratory of Diagnostic and Therapeutic Drug Research for Chronic Diseases, Changsha 410013, Hunan, China.; Hunan Key Laboratory of Organ Fibrosis, Changsha 410013, Hunan, China., Li M; Department of Medicinal Chemistry, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, Hunan, China.; Hunan Key Laboratory of Diagnostic and Therapeutic Drug Research for Chronic Diseases, Changsha 410013, Hunan, China.; Hunan Key Laboratory of Organ Fibrosis, Changsha 410013, Hunan, China., Wang Y; Department of Medicinal Chemistry, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, Hunan, China.; Hunan Key Laboratory of Diagnostic and Therapeutic Drug Research for Chronic Diseases, Changsha 410013, Hunan, China.; Hunan Key Laboratory of Organ Fibrosis, Changsha 410013, Hunan, China., Gao R; Key Laboratory of Study and Discovery of Small Targeted Molecules of Hunan Province, Department of Pharmacy, School of Medicine, Hunan Normal University, Changsha 410013, Hunan, China., Chen Z; Department of Medicinal Chemistry, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, Hunan, China.; Hunan Key Laboratory of Diagnostic and Therapeutic Drug Research for Chronic Diseases, Changsha 410013, Hunan, China.; Hunan Key Laboratory of Organ Fibrosis, Changsha 410013, Hunan, China., Jin Z; College of Biology, Hunan University, Changsha 410082, Hunan, China., Hu L; Key Laboratory of Study and Discovery of Small Targeted Molecules of Hunan Province, Department of Pharmacy, School of Medicine, Hunan Normal University, Changsha 410013, Hunan, China., Li Q; Department of Medicinal Chemistry, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, Hunan, China.; Hunan Key Laboratory of Diagnostic and Therapeutic Drug Research for Chronic Diseases, Changsha 410013, Hunan, China.; Hunan Key Laboratory of Organ Fibrosis, Changsha 410013, Hunan, China.

المصدر: Journal of medicinal chemistry [J Med Chem] 2024 Aug 08; Vol. 67 (15), pp. 13474-13490. Date of Electronic Publication: 2024 Jul 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Soluble Guanylyl Cyclase*/metabolism , HSP110 Heat-Shock Proteins*/metabolism , HSP110 Heat-Shock Proteins*/antagonists & inhibitors, Animals ; Humans ; Rats ; Rats, Sprague-Dawley ; Drug Discovery ; Pulmonary Arterial Hypertension/drug therapy ; Pulmonary Arterial Hypertension/metabolism ; Male ; Structure-Activity Relationship ; Hypertension, Pulmonary/drug therapy ; Vascular Remodeling/drug effects

المؤلفون: Smimmo M; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy., Casale V; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy., Casillo GM; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy., Mitidieri E; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy., d'Emmanuele di Villa Bianca R; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy., Bello I; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy., Schettino A; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy., Montanaro R; Department of Science, University of Basilicata, Potenza, Italy., Brancaleone V; Department of Science, University of Basilicata, Potenza, Italy., Indolfi C; Department of Molecular Medicine and Medical Biotechnology, School of Medicine and Surgery, University of Naples Federico II, Naples 80131, Italy., Cirino G; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy., Di Lorenzo A; Department of Pathology and Laboratory Medicine Center for Vascular Biology, Weill Cornell Medical College, Cornell University, New York, USA., Bucci M; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy. Electronic address: mrbucci@unina.it., Panza E; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy., Vellecco V; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy.

المصدر: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 May; Vol. 174, pp. 116466. Date of Electronic Publication: 2024 Mar 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE

مواضيع طبية MeSH: Hydrogen Sulfide*/metabolism , Hydrogen Sulfide*/pharmacology , Cyclic GMP*/metabolism , Metabolic Syndrome*/metabolism , Soluble Guanylyl Cyclase*/metabolism , Mice, Inbred C57BL*, Animals ; Mice ; Male ; Vasodilation/drug effects ; Signal Transduction/drug effects ; Nitric Oxide Synthase Type III/metabolism ; Humans ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/metabolism ; Nitric Oxide/metabolism ; Aorta/drug effects ; Aorta/metabolism ; Vascular Diseases/metabolism ; Disease Models, Animal

المؤلفون: Moraes RA; Laboratory of Cardiovascular Physiology and Pharmacology, Bioregulation Department, Federal University of Bahia, UFBA, Salvador, Bahia, Brazil; Gonçalo Moniz Institute, FIOCRUZ, Salvador, BA, Brazil., Brito DS; Laboratory of Cardiovascular Physiology and Pharmacology, Bioregulation Department, Federal University of Bahia, UFBA, Salvador, Bahia, Brazil; Gonçalo Moniz Institute, FIOCRUZ, Salvador, BA, Brazil., Araujo FA; Laboratory of Cardiovascular Physiology and Pharmacology, Bioregulation Department, Federal University of Bahia, UFBA, Salvador, Bahia, Brazil; Gonçalo Moniz Institute, FIOCRUZ, Salvador, BA, Brazil., Jesus RLC; Laboratory of Cardiovascular Physiology and Pharmacology, Bioregulation Department, Federal University of Bahia, UFBA, Salvador, Bahia, Brazil., Silva LB; Laboratory of Cardiovascular Physiology and Pharmacology, Bioregulation Department, Federal University of Bahia, UFBA, Salvador, Bahia, Brazil., Sá DS; Federal Institute of Bahia, IFBA, Salvador, BA, Brazil., Silva da Silva CD; Federal Institute of Bahia, IFBA, Salvador, BA, Brazil., Pernomian L; Department of Cell Biology and Anatomy, University of South Carolina, Columbia, SC, USA; Cardiovascular Translational Research Center, University of South Carolina, Columbia, SC, USA., Wenceslau CF; Department of Cell Biology and Anatomy, University of South Carolina, Columbia, SC, USA; Cardiovascular Translational Research Center, University of South Carolina, Columbia, SC, USA., Priviero F; Department of Cell Biology and Anatomy, University of South Carolina, Columbia, SC, USA; Cardiovascular Translational Research Center, University of South Carolina, Columbia, SC, USA., Webb RC; Department of Cell Biology and Anatomy, University of South Carolina, Columbia, SC, USA; Cardiovascular Translational Research Center, University of South Carolina, Columbia, SC, USA., Silva DF; Laboratory of Cardiovascular Physiology and Pharmacology, Bioregulation Department, Federal University of Bahia, UFBA, Salvador, Bahia, Brazil; Gonçalo Moniz Institute, FIOCRUZ, Salvador, BA, Brazil. Electronic address: darizy.silva@ufba.br.

المصدر: European journal of pharmacology [Eur J Pharmacol] 2024 Sep 15; Vol. 979, pp. 176822. Date of Electronic Publication: 2024 Jul 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Vasodilation*/drug effects , Nitric Oxide Donors*/pharmacology , Rats, Wistar* , Nitric Oxide*/metabolism , Soluble Guanylyl Cyclase*/metabolism , Sarcoplasmic Reticulum Calcium-Transporting ATPases*/metabolism , Potassium Channels*/metabolism , Cyclic GMP-Dependent Protein Kinases*/metabolism , Cyclic GMP*/metabolism , Signal Transduction*/drug effects, Animals ; Male ; Rats ; Mesenteric Arteries/drug effects ; Mesenteric Arteries/physiology ; Guanylate Cyclase/metabolism ; Enzyme Activation/drug effects

المؤلفون: Che Y; Department of Cardiology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, 466-8550, Japan., Shimizu Y; Department of Cardiology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, 466-8550, Japan. shimi123@med.nagoya-u.ac.jp., Hayashi T; Department of Cardiology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, 466-8550, Japan., Suzuki J; Department of Cardiology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, 466-8550, Japan., Pu Z; Department of Cardiology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, 466-8550, Japan., Tsuzuki K; Department of Cardiology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, 466-8550, Japan., Narita S; Department of Cardiology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, 466-8550, Japan., Shibata R; Department of Advanced Cardiovascular Therapeutics, Nagoya University Graduate School of Medicine, Nagoya, 466-8550, Japan., Murohara T; Department of Cardiology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, 466-8550, Japan.

المصدر: Scientific reports [Sci Rep] 2024 May 11; Vol. 14 (1), pp. 10777. Date of Electronic Publication: 2024 May 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Chronobiology Disorders*/complications , Chronobiology Disorders*/metabolism , CLOCK Proteins*/metabolism , CLOCK Proteins*/genetics , Cyclic GMP*/metabolism , Heart Failure*/metabolism , Heart Failure*/etiology , Heart Failure*/physiopathology , Soluble Guanylyl Cyclase*/metabolism, Animals ; Male ; Mice ; Circadian Rhythm/physiology ; Cyclic GMP-Dependent Protein Kinase Type I/metabolism ; Cyclic GMP-Dependent Protein Kinase Type I/genetics ; Disease Models, Animal ; Mice, Inbred C57BL ; Myocytes, Cardiac/metabolism ; Phenotype ; Signal Transduction ; Stroke Volume

المؤلفون: Stamerra CA; Department of Internal Medicine-Mazzoni Hospital, Ascoli Piceno, Italy., Di Giosia P; Department of Internal Medicine-Mazzoni Hospital, Ascoli Piceno, Italy., Giorgini P; Department of Emergency-Madonna del Soccorso Hospital, San Benedetto del Tronto, Italy., Jamialahmadi T; Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.; Medical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Sahebkar A; Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran. amir_saheb2000@yahoo.com.; Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. amir_saheb2000@yahoo.com.

المصدر: Current atherosclerosis reports [Curr Atheroscler Rep] 2024 May; Vol. 26 (5), pp. 177-187. Date of Electronic Publication: 2024 Apr 02.

نوع المنشور: Journal Article; Meta-Analysis; Systematic Review; Review

بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 100897685 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1534-6242 (Electronic) Linking ISSN: 15233804 NLM ISO Abbreviation: Curr Atheroscler Rep Subsets: MEDLINE

مواضيع طبية MeSH: Randomized Controlled Trials as Topic* , Heart Failure*/drug therapy , Heart Failure*/mortality , Soluble Guanylyl Cyclase*/metabolism , Natriuretic Peptide, Brain*/therapeutic use, Humans ; Peptide Fragments/therapeutic use ; Stroke Volume/drug effects ; Guanylyl Cyclase C Agonists/therapeutic use ; Treatment Outcome

المؤلفون: Arayici ME; Department of Biostatistics and Medical Informatics, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.; Department of Public Health, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey., Gunes H; Department of Cardiology, Izmir Faculty of Medicine, University of Health Sciences, İzmir, Turkey., Ellidokuz H; Department of Biostatistics and Medical Informatics, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey., Yilmaz MB; Department of Cardiology, Faculty of Medicine, Dokuz Eylül University, Inciralti-Balcova, 35340, İzmir, Turkey. prof.dr.mbyilmaz@gmail.com.

المصدر: Scientific reports [Sci Rep] 2024 Mar 24; Vol. 14 (1), pp. 6987. Date of Electronic Publication: 2024 Mar 24.

نوع المنشور: Meta-Analysis; Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Heart Failure*/drug therapy , Soluble Guanylyl Cyclase*/adverse effects, Humans ; Anemia/chemically induced ; Hypotension/chemically induced ; Randomized Controlled Trials as Topic

المؤلفون: Zhao Y; Department of Critical Care Medicine, Shengjing Hospital of China Medical University, Shenyang, China., Zang B; Department of Critical Care Medicine, Shengjing Hospital of China Medical University, Shenyang, China., Wang Q; Department of Emergency, The Fourth Affiliated Hospital of China Medical University, Shenyang, China.

المصدر: Shock (Augusta, Ga.) [Shock] 2024 Mar 01; Vol. 61 (3), pp. 333-339. Date of Electronic Publication: 2023 Nov 22.

نوع المنشور: Meta-Analysis; Systematic Review; Journal Article

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9421564 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-0514 (Electronic) Linking ISSN: 10732322 NLM ISO Abbreviation: Shock

مواضيع طبية MeSH: Heart Failure*/drug therapy , Heart Failure*/mortality , Stroke Volume*/drug effects , Soluble Guanylyl Cyclase*/metabolism, Humans ; Quality of Life ; Guanylyl Cyclase C Agonists/therapeutic use

المؤلفون: Montfort WR; Department of Chemistry & Biochemistry, University of Arizona, Tucson, AZ 85721, USA. Electronic address: montfort@arizona.edu.

المصدر: Journal of molecular biology [J Mol Biol] 2024 Feb 01; Vol. 436 (3), pp. 168235. Date of Electronic Publication: 2023 Aug 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2985088R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1089-8638 (Electronic) Linking ISSN: 00222836 NLM ISO Abbreviation: J Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Aryl Hydrocarbon Receptor Nuclear Translocator*/chemistry , Nitric Oxide*/metabolism , Soluble Guanylyl Cyclase*/chemistry , Soluble Guanylyl Cyclase*/genetics, Animals ; Humans ; Heme/metabolism ; Signal Transduction ; Protein Domains

المؤلفون: Yang J; Department of Medicine, Unit of Cardiology, Karolinska Institutet, Stockholm, Sweden., Sundqvist ML; Department of Physiology, Nutrition and Biomechanics, The Swedish School of Sport and Health Sciences, Stockholm, Sweden., Zheng X; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden., Jiao T; Department of Medicine, Unit of Cardiology, Karolinska Institutet, Stockholm, Sweden., Collado A; Department of Medicine, Unit of Cardiology, Karolinska Institutet, Stockholm, Sweden., Tratsiakovich Y; Department of Medicine, Unit of Cardiology, Karolinska Institutet, Stockholm, Sweden., Mahdi A; Department of Medicine, Unit of Cardiology, Karolinska Institutet, Stockholm, Sweden., Tengbom J; Department of Medicine, Unit of Cardiology, Karolinska Institutet, Stockholm, Sweden., Mergia E; Institute for Pharmacology and Toxicology, Ruhr-University Bochum, Bochum, Germany., Catrina SB; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden., Zhou Z; Department of Medicine, Unit of Cardiology, Karolinska Institutet, Stockholm, Sweden., Carlström M; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden., Akaike T; Department of Environmental Medicine and Molecular Toxicology, Tohoku University Graduate School of Medicine, Sendai, Japan., Cortese-Krott MM; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.; Myocardial Infarction Laboratory, Division of Cardiology, Pneumology and Vascular Medicine, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany., Weitzberg E; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden., Lundberg JO; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden., Pernow J; Department of Medicine, Unit of Cardiology, Karolinska Institutet, Stockholm, Sweden.; Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden.

المصدر: The Journal of clinical investigation [J Clin Invest] 2023 Sep 01; Vol. 133 (17). Date of Electronic Publication: 2023 Sep 01.

نوع المنشور: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

مواضيع طبية MeSH: Cyclic GMP* , Erythrocytes* , Soluble Guanylyl Cyclase* , Cardiotonic Agents*, Animals ; Mice ; Hypoxia ; Myocytes, Cardiac ; Nitrates ; Nitric Oxide ; Rats ; Humans

المؤلفون: Chakrabarty B; School of Physiology, Pharmacology & Neuroscience, University of Bristol, Bristol, UK., Winder M; Department of Pharmacology, University of Gothenburg, Gothenburg, Sweden., Kanai AJ; Departments of Medicine and Pharmacology & Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Hashitani H; Department of Cell Physiology, Nagoya City University, Nagoya, Japan., Drake M; Department of Surgery and Cancer, Hammersmith Hospital, London, UK., Abrams P; Bristol Urological Institute, North Bristol NHS Trust, Bristol, UK., Fry CH; School of Physiology, Pharmacology & Neuroscience, University of Bristol, Bristol, UK.

المصدر: Neurourology and urodynamics [Neurourol Urodyn] 2024 Aug; Vol. 43 (6), pp. 1344-1352. Date of Electronic Publication: 2023 Oct 30.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Alan R. Liss Country of Publication: United States NLM ID: 8303326 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6777 (Electronic) Linking ISSN: 07332467 NLM ISO Abbreviation: Neurourol Urodyn Subsets: MEDLINE

مواضيع طبية MeSH: Nitric Oxide*/metabolism , Urinary Bladder*/drug effects , Urinary Bladder*/metabolism , Urinary Bladder*/innervation , Signal Transduction*, Humans ; Animals ; Cyclic GMP/metabolism ; Soluble Guanylyl Cyclase/metabolism ; Urinary Bladder Diseases/metabolism ; Urinary Bladder Diseases/physiopathology ; Urinary Bladder Diseases/drug therapy ; Muscle, Smooth/metabolism ; Muscle, Smooth/drug effects