المؤلفون: Chatrikhi, Rakesh, Feeney, Callen F, Pulvino, Mary J, Alachouzos, Georgios, MacRae, Andrew J, Falls, Zackary, Rai, Sumit, Brennessel, William W, Jenkins, Jermaine L, Walter, Matthew J, Graubert, Timothy A, Samudrala, Ram, Jurica, Melissa S, Frontier, Alison J, Kielkopf, Clara L

المصدر: Cell Chemical Biology. 28(8)

مصطلحات موضوعية: Genetics, Cancer, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Female, HEK293 Cells, Humans, K562 Cells, Molecular Docking Simulation, Molecular Structure, RNA Precursors, RNA Splicing, RNA, Neoplasm, Small Molecule Libraries, Splicing Factor U2AF, S34F mutant, U2AF(35), U2AF(65), U2AF1, myelodysplastic syndrome, ribonucleoprotein targeting, spliceosome inhibition, splicing factor mutation, therapeutic strategy

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2sk8s5gr

مصطلحات موضوعية: Acute Myeloid Leukemia, FLT3/ITD, Alternatieve Splicing, SF3B1, Pediatric Acute Myeloid Leukemia, Splicing Factor Mutation, Alternative Splicing, Splicing Deregulatie, Leukemie in Kinderen, Acute Myeloïde Leukemie, Splicing Regulator Mutatie, Splicing Modulation, Splicing Deregulation, Splicing Modulatie

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______4612::3c4d8dde679956b0a91ef6747801fdb5
https://research.vu.nl/en/publications/d8faf35c-e79a-4702-85e8-47a781d2fc41

المؤلفون: van der Werf, IM

المساهمون: Kaspers, Gertjan, Cloos, Jacqueline, Wojtuszkiewicz, Anna, Groen, Richard, Hematology laboratory, Kaspers, G.J.L., Cloos, J., Wojtuszkiewicz, Anna Monika, Groen, R.

المصدر: van der Werf, I M 2022, ' Splicing Deregulation and Splicing Modulation in Acute Myeloid Leukemia : DNA is not Destiny ', Dr., Vrije Universiteit Amsterdam .
van der Werf, IM 2022, ' Splicing Deregulation and Splicing Modulation in Acute Myeloid Leukemia: DNA is not Destiny ', Doctor of Philosophy, Vrije Universiteit Amsterdam, Netherlands . < https://hdl.handle.net/1871.1/d8faf35c-e79a-4702-85e8-47a781d2fc41 >

مصطلحات موضوعية: Acute Myeloid Leukemia, FLT3/ITD, Alternatieve Splicing, SF3B1, Pediatric Acute Myeloid Leukemia, Splicing Factor Mutation, Alternative Splicing, Splicing Deregulatie, hemic and lymphatic diseases, Leukemie in Kinderen, Acute Myeloïde Leukemie, Splicing Regulator Mutatie, Splicing Modulation, Splicing Deregulation, neoplasms, Splicing Modulatie

وصف الملف: image/jpeg; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6dd4e80e27187b97e6c318d9fc1758e7
https://hdl.handle.net/1871.1/d8faf35c-e79a-4702-85e8-47a781d2fc41

المؤلفون: Mary J. Pulvino, Zackary Falls, Matthew J. Walter, Rakesh Chatrikhi, Andrew J. MacRae, Jermaine L. Jenkins, Callen F. Feeney, Clara L. Kielkopf, Melissa S. Jurica, William W. Brennessel, Sumit Rai, Georgios Alachouzos, Alison J. Frontier, Timothy A. Graubert, Ram Samudrala

المصدر: Cell chemical biology, vol 28, iss 8
Cell Chem Biol

مصطلحات موضوعية: Clinical Biochemistry, Mutant, U2AF(65), 01 natural sciences, Biochemistry, Drug Discovery, RNA Precursors, RNA, Neoplasm, Cancer, U2AF2, Molecular Structure, Chemistry, ribonucleoprotein targeting, S34F mutant, spliceosome inhibition, Small molecule, Cell biology, Molecular Docking Simulation, 5.1 Pharmaceuticals, RNA splicing, Molecular Medicine, Female, Development of treatments and therapeutic interventions, Macromolecule, Protein subunit, RNA Splicing, Mutagenesis (molecular biology technique), Biology, splicing factor mutation, Article, U2AF(35), Small Molecule Libraries, U2AF1, Genetics, Humans, therapeutic strategy, Molecular Biology, Pharmacology, 010405 organic chemistry, Mutagenesis, RNA, Splicing Factor U2AF, 0104 chemical sciences, myelodysplastic syndrome, HEK293 Cells, Docking (molecular), Neoplasm, K562 Cells, Function (biology)

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::895a2cf142ec23caeae71ba14975f65e
https://escholarship.org/uc/item/2sk8s5gr

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

المؤلفون: Rebecca C. Poulos, Shiyong Ma, Ranjeeta Menon, Jason W. H. Wong

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Genetics, Whole genome sequencing, Jurkat, In silico, Phosphoproteomics, phosphoproteomics, Biology, Proteogenomics, Proteomics, Jurkat cells, splicing factor mutation, DNA sequencing, 03 medical and health sciences, 030104 developmental biology, Oncology, RNA splicing, RNA-seq, Research Paper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a977fb5b2604ca58db72f4bf4f1747
http://europepmc.org/articles/PMC5707065

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

مصطلحات الفهرس: Alternatieve Splicing, Splicing Modulatie, Splicing Deregulatie, Splicing Regulator Mutatie, SF3B1, FLT3/ITD, Acute Myeloïde Leukemie, Leukemie in Kinderen, Alternative Splicing, Splicing Modulation, Splicing Deregulation, Splicing Factor Mutation, Acute Myeloid Leukemia, Pediatric Acute Myeloid Leukemia, PhD-Thesis - Research and graduation internal

URL: https://research.vu.nl/en/publications/d8faf35c-e79a-4702-85e8-47a781d2fc41
https://research.vu.nl/ws/files/149261926/I%20M%20%20van%20der%20Werf%20-%20thesis.pdf
https://research.vu.nl/ws/files/149261930/I%20M%20%20van%20der%20Werf%20-%20toc.pdf
https://research.vu.nl/ws/files/149261932/I%20M%20%20van%20der%20Werf%20-%20title_page.pdf
https://research.vu.nl/ws/files/149261934/I%20M%20%20van%20der%20Werf%20-%20thesis_redacted.pdf
https://research.vu.nl/ws/files/149261926/I%20M%20%20van%20der%20Werf%20-%20thesis.pdf
https://research.vu.nl/ws/files/149261928/I%20M%20%20van%20der%20Werf%20-%20cover.jpg
https://research.vu.nl/ws/files/149261930/I%20M%20%20van%20der%20Werf%20-%20toc.pdf
https://research.vu.nl/ws/files/149261932/I%20M%20%20van%20der%20Werf%20-%20title_page.pdf
https://research.vu.nl/ws/files/149261934/I%20M%20%20van%20der%20Werf%20-%20thesis_redacted.pdf