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المؤلفون: Masaaki Shiina, Masatoshi Ishigami, Takanori Ito, Teiji Kuzuya, Asuka Kato, Norie Yamada, Takanobu Kato, Tetsuya Ishikawa, Masamichi Muramatsu, Mitsuhiro Fujishiro, Tomohisa Tanaka, Kohji Moriishi, Yoji Ishizu, Yoshiki Murakami, Hussein H. Aly, Hironori Nishitsuji, Kunitada Shimotohno, Asako Murayama, Takaji Wakita, Takashi Honda
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1583-1598 (2021)مصطلحات موضوعية: Male, GEq, genome equivalent, HBVcc, cell culture-generated HBV, Clone (cell biology), Cell Culture Techniques, RC799-869, medicine.disease_cause, Virus Replication, SS, single-stranded HBV DNA, NL, NanoLuc luciferase, PCR, polymerase chain reaction, Genes, Reporter, Original Research, Infectivity, RT, reverse transcription, HBc, Gastroenterology, virus diseases, RLU, relative light units, cccDNA, Transfection, Hepatitis B, Diseases of the digestive system. Gastroenterology, Middle Aged, HBsAg, hepatitis B surface antigen, Disease Progression, CHB, chronic hepatitis B, Female, cccDNA, covalently closed circular DNA, Genetic Engineering, wt, wild-type, Adult, Gene Expression Regulation, Viral, Hepatitis B virus, SDS, sodium dodecyl sulfate, HBeAg, hepatitis B e antigen, Biology, Models, Biological, Virus, RC, relaxed-circular HBV DNA, Viral Proteins, Hepatitis B, Chronic, HBcrAg, hepatitis B core-related antigen, ALT, alanine aminotransferase, medicine, HBVcc, Humans, IFN, interferon, Hepatitis, Polymorphism, Genetic, Hepatology, pgRNA, pregenomic RNA, HBc, hepatitis B core, NA, nucleos(t)ide analog, medicine.disease, Virology, digestive system diseases, HBV, hepatitis B virus, Amino Acid Substitution, DNA, Viral, SD, standard deviation, Biomarkers, DAPI, 4′,6-diamidino-2-phenylindole
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المؤلفون: Marina V. Rodnina, K. Vester, Dmitry Burakovskiy, Markus C. Wahl, Pohl Milón, Eva Absmeier, Tahereh Ghane, Petra Imhof, Karine F. Santos
المصدر: The Journal of Biological Chemistry
Journal of Biological Chemistryمصطلحات موضوعية: 0301 basic medicine, SF2, superfamily 2, intramolecular regulation, sn, small nuclear, T1, truncation 1, IG, immunoglobulin-like domain, Biochemistry, Substrate Specificity, HB, helical bundle domain, pre-mRNA, precursor messenger RNA, Protein structure, Tris, tris(hydroxymethyl)aminomethane, Adenosine Triphosphate, Adenine nucleotide, enzyme kinetics, Nucleotide, CC, C-terminal cassette, Amino Acids, chemistry.chemical_classification, biology, Chemistry, Adenine Nucleotides, Editors' Pick, NTR, N-terminal region, Ribonucleoproteins, Small Nuclear, RNA Helicase A, MD, molecular dynamics, Adenosine Diphosphate, superfamily 2 helicase, RNA splicing, HLH, helix–loop–helix domain, wt, wild type, 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften, RNA Helicases, Research Article, RNA helicase, NC, N-terminal cassette, Allosteric regulation, NTPase, nucleic-acid-dependent nucleotide triphosphatase, Molecular Dynamics Simulation, DSF, differential scanning fluorimetry, SEM, standard error of the mean, FRET, fluorescence resonance energy transfer, 03 medical and health sciences, h, human, Protein Domains, WH, winged-helix domain, protein conformation, Humans, Molecular Biology, RNP, ribonucleoprotein complex, Binding Sites, 030102 biochemistry & molecular biology, Helicase, Cell Biology, allosteric regulation, v/v, volume/volume, Kinetics, 030104 developmental biology, DTT, dithiothreitol, ss, single-stranded, Mutation, pre-mRNA splicing, biology.protein, Biophysics, BAC, bacterial artificial chromosome, mant, methylanthraniloyl, Structural communication, pre mRNA splicing
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebde8382e3bb7f7e295d497fb6fcc56
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المؤلفون: Jayakrishnan Nandakumar, Sherilyn Grill
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, Telomerase, Telomeric repeat-containing RNAs, RNP, ribonucleoprotein, dyskeratosis congenita, Biochemistry, Shelterin Complex, telomere shortening, CAB, Cajal body, TR, telomerase RNA, Ribonucleoprotein, Genetics, telomere, ds, double-stranded, Anemia, Aplastic, telomerase recruitment, HH, Hoyeraal–Hreidarsson, TBDs, telomere biology disorders, PUA, pseudouridine and archeosine transglycosylase, TERT, telomerase reverse transcriptase, telomeropathies, DC, dyskeratosis congenita, AA, aplastic anemia, PK/T, pseudoknot/template, NEXT, nuclear exosome targeting complex, Telomere-Binding Proteins, PCNA, proliferating cell nuclear antigen, Reviews, Biology, ICF, immunodeficiency, centromeric instability, and facial anomalies, PF, pulmonary fibrosis, telomerase, Dyskerin, 03 medical and health sciences, telomerase assembly, medicine, Humans, IPF, idiopathic pulmonary fibrosis, Telomerase reverse transcriptase, PARN, poly(A)-specific ribonuclease, Molecular Biology, TRBD, TERT RNA-binding domain, 030102 biochemistry & molecular biology, Cell Biology, medicine.disease, TEN, telomerase essential N-terminal domain, Telomere, 030104 developmental biology, BMF, bone marrow failure, Cajal body, ss, single-stranded, Mutation, IFD, insertion in fingers domain, TERRA, telomeric repeat-containing RNA, CP, Coats plus, Dyskeratosis congenita
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e182943ceb07a934e12abae625a17bbc
https://pubmed.ncbi.nlm.nih.gov/33482595 -
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المصدر: Chemical Engineering Journal
مصطلحات موضوعية: SODIS, Solar water disinfection, General Chemical Engineering, BCoV, Bovine Enteric Coronavirus), HKU1, Human CoV1, SBR, Sequential Batch Reactor, RNA, Ribose nucleic acid, βCoV, Betacoronavirus, T99.9, First order reaction time required for completion of 99.9%, 02 engineering and technology, WWT, Wastewater Treatment, 01 natural sciences, MERS-CoV, Middle East Respiratory Syndrome Coronavirus, FIPV, Feline infectious peritonitis virus, ORF, Open Reading Frame, PPE, Personal Protective Equipment, ASP, Activate Sludge Process, WBE, Wastewater-Based Epidemiology, PCR, Polymerase Chain Reaction, PAA, Para Acetic Acid, Coronavirus, AOPs, Advanced Oxidation Processes, HAV, Hepatitis A virus (HAV), Cl−, Chlorine, NCoV, Novel coronavirus, HCoV, Human CoV, virus diseases, ds, Double Stranded, Enteric virus, BoRv, Bovine Rotavirus Group A, ssDNA, Single Stranded DNA, PEG, Polyethylene Glycol, ClO2, Chlorine dioxide, 0210 nano-technology, DMEM, Dulbecco’s Modified Eagle Medium, TGEV, Transmissible Gastroenteritis, MHV, Murine hepatitis virus, EV, Echovirus 11, US-EPA, United States Environmental Protection Agency, AH, Absolute Humidity, TGEV, Porcine Coronavirus Transmissible Gastroenteritis Virus, dsDNA, Double Stranded DNA, H3N2, InfluenzaA, WWTPs, Wastewater Treatment Plants, DBP, Disinfection by-products, O2, Singlet Oxygen, Article, T90, First order reaction time required for completion of 90%, (h+), Photoholes, NTP, Non-Thermal Plasma, CVE, Coxsackievirus B5, H2O2, Hydrogen Peroxide, MWCNTs, Multiwalled Carbon Nanotubes, Enveloped virus, HEV, Hepatitis E virus, PFU, Plaque Forming Unit, CCA, Carbon Covered Alumina, Tyr, Tyrosine, H6N2, Avian influenza virus, ssRNA, Single Stranded RNA, Outbreak, PVDF, Polyvinylidene Fluoride, Qβ, bacteriophages, Virology, 0104 chemical sciences, NGS, Next generation sequencing, RONS, Reactive Oxygen and/or Nitrogen Species, Betacoronavirus, RH, Relative Humidity, viruses, SARS-CoV-1, Severe Acute Respiratory Syndrome Coronavirus 1, medicine.disease_cause, Industrial and Manufacturing Engineering, PMMoV, Pepper Mild Mottle Virus, dPCR, Digital PCR, FC, Free Chlorine, Trp, Tryptophan, E gene, Envelope protein gene, BVDV1, Bovine Viral Diarrhea Virus Type 1, MALDI-TOF MS, Mass Spectrometry, Pandemic, CNT, Carbon Nanotubes, N gene, Nucleocapsid protein gene, ICC-PCR, Integrated Cell Culture with PCR, DNA, deoxyribose nucleic acid, UV, Ultraviolet, Sewage, JCV, JCV polyomavirus, biology, PV-3, Poliovirus 3, Transmission (medicine), BSL, Biosafety Level, 021001 nanoscience & nanotechnology, RVA, Rotaviruses A, PTAF, Photocatalytic Titanium Apatite Filter, COVID-19, Coronavirus Disease 2019, CRFK, Crandell Reese feline kidney cell line (CRFK), qRT-PCR, quantitative RT-PCR, A-WWTS, Algal-WWTS, Cys, Cysteine, Middle East respiratory syndrome coronavirus, Context (language use), 010402 general chemistry, Airborne transmission, PMR, Photocatalytic Membrane Reactors, ACE2, Angiotensin-converting enzyme 2, PEC, Photoelectrocatalytical, medicine, Environmental Chemistry, FFP3, Filtering Face Piece, Met, Methionine, ComputingMethodologies_COMPUTERGRAPHICS, Aerosols, DBT, L2 and Delayed Brain Tumor Cell Cultures, COVID-19, PV-1, Polivirus-1, αCoV, Alphacoronavirus, MNV-1, Murine Norovirus, General Chemistry, log10, logarithm with base 10, ss, Single Stranded, HAdV, Human Adenovirus, biology.organism_classification, MBR, Membrane Bioreactor (MBR), Disinfection, BVDV2, Bovine Viral Diarrhea Virus Type 2, GI, Gastrointestinal tract, SARS-CoV-2, Severe Acute Respiratory Syndrome Coronavirus 2, O3, Ozone, RT-PCR, Real Time Polymerase Chain Reaction, STP, Sewage Treatment Plant, +ssRNA, Positive Sense Single-Stranded RNA
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المؤلفون: Dana Branzei, Barnabas Szakal
المصدر: DNA Repair
مصطلحات موضوعية: 0301 basic medicine, Genome instability, DNA End-Joining Repair, Base Pair Mismatch, NPS, Natural Pausing Sites, DNA-Directed DNA Polymerase, Biochemistry, DNA Mismatch Repair, Fork reversal, chemistry.chemical_compound, DNA Breaks, Double-Stranded, Polymerase, Genetics, Mammals, biology, Ubiquitin/SUMO modifications, SLDs, SUMO-like domains, CFS, Common Fragile Sites, DNA mismatch repair, DNA Replication, Saccharomyces cerevisiae Proteins, DNA damage, Mini Review, PCNA, proliferating cell nuclear antigen, HR, Homologous recombination, Computational biology, STR, Sgs1-Top3-Rmi1, Saccharomyces cerevisiae, DDR, DNA damage response, Genomic Instability, 03 medical and health sciences, DSBs, Double strand breaks, parasitic diseases, Chromosome replication, PCNA, Animals, Humans, Homologous recombination, Molecular Biology, DNA damage tolerance, PRR, Postreplication repair, DNA replication, HJ, Holliday Junction, DNA Helicases, Replication stress, Recombinational DNA Repair, Cell Biology, DNA, 030104 developmental biology, DDT, DNA damage tolerance, chemistry, TLS, Translesion Synthesis, biology.protein, ss, single stranded
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المؤلفون: Michael Kracht, M. Lienhard Schmitz, Vera V. Saul
المصدر: Biochimica et Biophysica Acta. Molecular Cell Research
مصطلحات موضوعية: ATL, adult T-cell leukemia/lymphoma, PRR, pattern recognition receptor, HBZ, basic leucine zipper factor, viruses, RIG-I, retinoic acid-inducible gene I, NIK, NF-κB-inducing kinase, Signal transduction, MyD88, myeloid differentiation primary response gene 88, RLRs, RIG-I-like receptors, NF-κB, TRAIL, TNF-related apoptosis inducing ligand, IKKε/TBK1, IκB kinase ε/TANK-binding kinase, STAMBPL1, STAM-binding protein-like 1, Interferon, TGFβ, transforming growth factor β, IKK, IκB kinase, TAB2, TGF-β activated kinase binding protein 2, IκB, inhibitor of NF-κB, TNF, tumor necrosis factor, cRNA, complementary RNA, ds, double-stranded, RIG-I, SUMO, small ubiquitin-related modifier, HTLV, human T cell leukemia virus, TAK1, TGF-β activated kinase 1, MDA5, Brd4, bromodomain-containing 4, RNA Helicase A, Cell biology, pro-IL-1β, pro-interleukin-1β, CARD, caspase activation and recruitment domain, RIPK2, receptor-interacting protein kinase 2, USP20, ubiquitin-specific peptidase, Viral evolution, MAVS, mitochondrial antiviral signaling protein, MDA5, melanoma differentiation factor 5, NF-κB, nuclear factor κB, TLRs, toll-like receptors, SC35, serine/arginine-rich splicing factor 2, LGP2, laboratory of genetics and physiology 2, medicine.drug, AIM2, absent in melanoma 2, RNA virus, vRNA, virion RNA, PI3K, phosphoinositide-3-kinase, Biology, Hsp90, heat shock protein 90 kDa, Article, Virus, OPTN, Optineurin, ASC, apoptosis-associated speck-like protein containing a carboxy-terminal CARD, NLRP3, NLR (Nod-like receptor) family, pyrin domain containing 3, medicine, IFN, interferon, SARS, severe acute respiratory syndrome, Interferon signaling, Molecular Biology, TRAF2, TNF receptor-associated factor 2, NS1, nonstructural protein 1, NEMO, NF-κB essential modulator, IRF3, interferon regulatory factor 3, PIASy, protein inhibitor of activated STAT y, RNA, DHX9, DEAH (Asp-Glu-Ala-His) box helicase 9, ATM, ataxia-telangiectasia mutated, Cell Biology, DDX3, DEAD (Asp-Glu-Ala-Asp) box helicase 3, biology.organism_classification, Virology, IAVs, influenza A viruses, ChIP-Seq, chromatin immunoprecipitation coupled to deep sequencing, ppp, triphosphate, PB1-F2, polymerase basic protein 1-frame 2, ss, single-stranded, PARP-1, poly(ADP-ribose)-polymerase-1, Ubc13, ubiquitin-conjugating 13, LTR, long terminal repeat, TAX1BP1, Tax-1 binding protein 1, WWOX, WW domain-containing oxidoreductase, Influenza virus
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المصدر: Virus Research, 234, 58-73
Virus Researchمصطلحات موضوعية: 0301 basic medicine, Enzyme complex, Cancer Research, Processivity factors, Transcription, Genetic, Arterivirus, viruses, CoV, coronavirus, Nidovirales, Virus Replication, medicine.disease_cause, PEDV, porcine epidemic diarrhea virus, chemistry.chemical_compound, Y2H, yeast 2-hybrid, TRS, transcription-regulatory sequence, RNA polymerase, ExoN, exoribonuclease, IVRA, in vitro RNA synthesis assay, Polymerase, Coronavirus, Subgenomic mRNA, Replication and transcription complex, Genetics, biology, RTC, replication and transcription complex, AV, arterivirus, DNA-Directed RNA Polymerases, Subgenomic mRNA synthesis, Infectious Diseases, 5-AZC, 5-azacytidine, RNA, Viral, Polymerase fidelity, HCoV-229E, human coronavirus 229E, Exoribonuclease activity, kb, kilobases, wt, wild-type, RBV, ribavirin, TGEV, transmissible gastroenteritis virus, PNS, post-nuclear supernatant, M2H, mammalian 2-hybrid, RNA-dependent RNA polymerase, NiRAN, nidovirus RdRp-associated nucleotidyltransferase, EAV, equine arteritis virus, IMPDH, inosine-5′-monophosphate dehydrogenase, Article, ZBD, zinc-binding domain, RdRp, RNA dependent RNA polymerase, 03 medical and health sciences, ORF, open reading frame, Virology, MHV, murine hepatitis coronavirus, medicine, Animals, Humans, CBV3, coxsackievirus B3, nsp, non-structural protein, ub, ubiquitin, SARS, severe acute resporiatory syndrome, EM, electron microscopy, pp, polyprotein, FCoV, feline coronavirus, MERS, Middle East respiratory syndrome, sg, subgenomic, RNA, PABP, Poly(A)-binding protein, PRRSV, porcine reproductive and respiratory syndrome virus, 030104 developmental biology, chemistry, ss, single-stranded, FMDV, foot and mouth disease virus, biology.protein, 5-FU, 5-fluorouracil, Protein Multimerization
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f03c18d2c9c41509c1f43138ecc53a7
https://hdl.handle.net/1887/114569 -
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المصدر: Plasmid
مصطلحات موضوعية: T4SS, type IV secretion system, Gene Transfer, Horizontal, Antibiotic resistance, Streptomycetaceae, DNA, Single-Stranded, Virulence, Review, Plasmid, Bacterial cell structure, TMH, trans-membrane helix, Type IV secretion, 03 medical and health sciences, chemistry.chemical_compound, Bacterial Proteins, Cell Wall, Operon, Conjugative transfer, Enterococcus faecalis, Secretion, G+, Gram-positive, aa, amino acid(s), Bacterial Secretion Systems, Molecular Biology, 030304 developmental biology, Clostridium, Genetics, G−, Gram-negative, 0303 health sciences, biology, 030306 microbiology, Bacterial conjugation, Biological Transport, DNA, Gene Expression Regulation, Bacterial, T4S, type IV secretion, PG, peptidoglycan, biology.organism_classification, chemistry, Conjugation, Genetic, TMD, trans-membrane domain, Mobile genetic elements, ss, single stranded, Enterococcus, Bacteria, ds, double stranded, Plasmids
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المؤلفون: Victor I. Ugarov, Alexander B. Chetverin
المصدر: Journal of Molecular Biology
مصطلحات موضوعية: DLU, digital light units, RQ135 RNA, an RQ RNA whose most abundant subspecies is 135 nt long, GTP', Molecular Sequence Data, RNA-dependent RNA polymerase, Guanosine, ATA, aurintricarboxylic acid, Biology, closed conformation, Article, chemistry.chemical_compound, PCR, polymerase chain reaction, RQ RNA (termed so for being Replicable by Qβ replicase), a non-genomic RNA capable of exponential amplification by Qβ replicase, interacting termini, Structural Biology, RNA polymerase, Enzyme Stability, Aurintricarboxylic acid, Molecular Biology, PAGE, polyacrylamide gel electrophoresis, Genetics, Base Sequence, ds, double-stranded, RNA replicase, Q beta Replicase, replicative intermediate, RNA, Templates, Genetic, biology.organism_classification, Cell biology, processive synthesis, Template, chemistry, ss, single-stranded, Mutation, NTP, ribonucleoside 5′-triphosphate, Nucleic Acid Conformation, Guanosine Triphosphate, nt, nucleotide(s), Bacteriophage Qβ
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المؤلفون: Swadeshmukul Santra, Logan M Byrne, Astha Malhotra, Padmavathy Tallury
المصدر: Advanced Drug Delivery Reviews
مصطلحات موضوعية: SPIO, superparamagnetic iron oxide, FAM-SE, (5-carboxy-fluorescein succinimidyl ester), FSNPS, fluorescent silica nanoparticles, Engineered nanomaterials, Human immunodeficiency virus (HIV), MRS, magnetic relaxation sensors, Pharmaceutical Science, SMCC, Succinimidyl-4-(N-Maleimidomethyl)Cyclohexane-1-Carboxylate, RSV, Respiratory Syncytial Virus, Ova, Ovalbumin, 02 engineering and technology, POA, adopted pigeon ovalbumin, FRET, Förster resonance energy transfer, medicine.disease_cause, 01 natural sciences, Multiplexing, R6G-SE, (5-carboxyrhodamine 6G, succinimidyl ester), CCMV, cow pea chlorotic mottle virus, SEC1, staphylococcal enterotoxin C1, FNP-IIFM, fluorescent nanoparticle-based indirect immunofluorescence microscopy, SQUID, Superconducting Quantum Interference Device, H. pyroli, Helicobacter pyroli, MGNP, magnetic glycol nanoparticles, Nanotechnology, PCR, Polymerase Chain Reaction, Gd-DOTA, Gadolinium-1,4,7,10-tetraazacyclododecane tetraacetic acid, Fluorescent nanoparticles, ELISA, Enzyme Linked Immuno Sorbent Assay, Chemistry, Diagnostic test, RuBpy, Tris(bipyridine) ruthenium (II) dichloride, HRS, Hyper-Rayleigh scattering, Bacterial Infections, Qdot-B, Qdot-barcodes, 021001 nanoscience & nanotechnology, Bg, Bacillus globigii, MNP, magnetic nanoparticles, 3. Good health, HIV, human immunodeficiency virus, Colorimetric assay, Metals, HCV, hepatitis C virus, PA, anthrax protective agent, 0210 nano-technology, RLS, Resonance Light Scattering, Viral imaging, ds, double stranded, MALDI-MS, Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry, Diagnostic Imaging, HSV-1, Herpes simplex Virus type 1, ATP, adenosine triphosphate, Metallic nanostructures, Early detection, OsBpy, Tris (2, 2′bipyridyl) osmium bis (hexafluorophosphate), SPR, surface plasmon resonance, Superparamagnetic nanoparticles, NMR, Nuclear Magnetic Resonance, 010402 general chemistry, Infections, ROX-SE, (6-carboxy-X-rhodamine, succinimidyl ester), ICP-MS, inductively coupled plasma mass spectrometry, Fluorescence, Article, WHO, World Health Organization, MRI, Magnetic Resonance Imaging, Magnetics, HSV-2, Herpes simplex Virus type 2, Surface plasmon resonance, medicine, TMR-SE, (carboxytetramethylrhodamine, succinimidyl ester), Magnetic nanosensors, Humans, TEM, transmission electron microscopy, Developing Countries, Zn-DPA, Zn (II)-dipicolylamine, Infectious virus, NPs, nanoparticles, Eu III, Europium, Qdots, quantum dots, SpA, Protein A, LOD, limit of detection, Bacterial detection, FITC, Fluorescein Isothiocyanate, CT, cholera toxin, SERS, surface enhanced Raman scattering, CFU, colony forming unit, 0104 chemical sciences, HBV, hepatitis B virus, CaDPA, calcium dipicolinate, IR, Infra Red, Nanoparticles, Immunomagnetic separation, ss, single stranded, Au NP, gold nanoparticle
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