المؤلفون: Li X, Zou L

المصدر: The Journal of clinical investigation [J Clin Invest] 2024 Jul 15; Vol. 134 (14). Date of Electronic Publication: 2024 Jul 15.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

مواضيع طبية MeSH: Poly(ADP-ribose) Polymerase Inhibitors*/pharmacology , BRCA2 Protein*/genetics , BRCA1 Protein*/genetics , BRCA1 Protein*/metabolism , Synthetic Lethal Mutations*/genetics, Humans ; Neoplasms/drug therapy ; Neoplasms/genetics ; Neoplasms/pathology ; Animals ; Female ; Drug Resistance, Neoplasm/genetics ; Drug Resistance, Neoplasm/drug effects

المؤلفون: Sun Y; Department of Clinical Laboratory Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China., Chen J; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China., Hong JH; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore., Xiao R; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China., Teng Y; Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology Guangzhou, Guangzhou, China., Wang P; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China., Deng P; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China., Yu Z; Department of Colorectal Surgery, the Sixth Affiliated Hospital, Sun Yat-sen University, 510655, Guangzhou, China., Chan JY; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore., Chai KXY; Lymphoma Translational Research Laboratory, Division of Cellular and Molecular Research, National Cancer Centre Singapore, Singapore, Singapore., Gao J; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China., Wang Y; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China., Pan L; Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology Guangzhou, Guangzhou, China., Liu L; Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology Guangzhou, Guangzhou, China., Liu S; Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology Guangzhou, Guangzhou, China., Teh BT; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore.; Laboratory of Cancer Epigenome, Division of Medical Sciences, National Cancer Centre Singapore, Singapore, Singapore.; Genome Institute of Singapore, A*STAR, Singapore, Singapore., Yu Q; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore.; Genome Institute of Singapore, A*STAR, Singapore, Singapore., Lim ST; Director's office, National Cancer Centre Singapore, Singapore, Singapore.; Office of Education, Duke-NUS Medical School, Singapore, Singapore., Li W; Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology Guangzhou, Guangzhou, China., Xu B; Department of Laboratory Medicine, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China., Ong CK; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore.; Lymphoma Translational Research Laboratory, Division of Cellular and Molecular Research, National Cancer Centre Singapore, Singapore, Singapore., Tan J; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China. tanjing@sysucc.org.cn.; Laboratory of Cancer Epigenome, Division of Medical Sciences, National Cancer Centre Singapore, Singapore, Singapore. tanjing@sysucc.org.cn.

المصدر: Oncogene [Oncogene] 2024 Jul; Vol. 43 (28), pp. 2172-2183. Date of Electronic Publication: 2024 May 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

مواضيع طبية MeSH: CREB-Binding Protein*/genetics , CREB-Binding Protein*/metabolism , Aurora Kinase A*/genetics , Aurora Kinase A*/metabolism , Aurora Kinase A*/antagonists & inhibitors , Proto-Oncogene Proteins c-myc*/genetics , Proto-Oncogene Proteins c-myc*/metabolism , Synthetic Lethal Mutations*, Humans ; Animals ; Mice ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Apoptosis/genetics ; Xenograft Model Antitumor Assays

المؤلفون: Kyrkou A; German Cancer Research Center (DKFZ), Division B140, 69120, Heidelberg, Germany.; Heidelberg University, Institute of Human Genetics, 69120, Heidelberg, Germany., Valla R; German Cancer Research Center (DKFZ), Division B140, 69120, Heidelberg, Germany.; Heidelberg University, Institute of Human Genetics, 69120, Heidelberg, Germany., Zhang Y; German Cancer Research Center (DKFZ), Division B140, 69120, Heidelberg, Germany.; Heidelberg University, Institute of Human Genetics, 69120, Heidelberg, Germany., Ambrosi G; German Cancer Research Center (DKFZ), Div. Signaling and Functional Genomics, 69120, Heidelberg, Germany., Laier S; Core Facility Tumor Models, German Cancer Research Center (DKFZ), Heidelberg, Germany., Müller-Decker K; Core Facility Tumor Models, German Cancer Research Center (DKFZ), Heidelberg, Germany., Boutros M; Heidelberg University, Institute of Human Genetics, 69120, Heidelberg, Germany.; German Cancer Research Center (DKFZ), Div. Signaling and Functional Genomics, 69120, Heidelberg, Germany., Teleman AA; German Cancer Research Center (DKFZ), Division B140, 69120, Heidelberg, Germany. a.teleman@dkfz.de.; Heidelberg University, Institute of Human Genetics, 69120, Heidelberg, Germany. a.teleman@dkfz.de.

المصدر: Nature communications [Nat Commun] 2024 Jun 15; Vol. 15 (1), pp. 5115. Date of Electronic Publication: 2024 Jun 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Schwann Cells*/metabolism , CRISPR-Cas Systems* , Glucosephosphate Dehydrogenase*/metabolism , Glucosephosphate Dehydrogenase*/genetics , Neurofibromin 2*/metabolism , Neurofibromin 2*/genetics , Coenzyme A Ligases*/metabolism , Coenzyme A Ligases*/genetics , Synthetic Lethal Mutations*, Humans ; Animals ; Neurofibromatosis 2/metabolism ; Neurofibromatosis 2/genetics ; NADP/metabolism ; Mice ; Oxidation-Reduction

المؤلفون: Wang F; Department of Obstetrics and Gynecology, The First Affiliated Hospital of Soochow University, Suzhou, China., Yu X; Department of Imaging Department, The First Affiliated Hospital of Soochow University, Suzhou, China., Qian J; Department of Obstetrics and Gynecology, The First Affiliated Hospital of Soochow University, Suzhou, China., Cao Y; Department of Obstetrics and Gynecology, The First Affiliated Hospital of Soochow University, Suzhou, China., Dong S; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, China., Zhan S; Department of Pathology, The First Affiliated Hospital of Soochow University, Suzhou, China., Lu Z; Department of Experimental Therapeutics, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA., Bast RC Jr; Department of Experimental Therapeutics, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA., Song Q; Department of Obstetrics and Gynecology, Nanjing University of Chinese Medicine Affiliated Suzhou Hospital, Suzhou, China., Chen Y; Department of Obstetrics and Gynecology, The First Affiliated Hospital of Soochow University, Suzhou, China. Electronic address: chenyouguo@suda.edu.cn., Zhang Y; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, China. Electronic address: zhangyi@suda.edu.cn., Zhou J; Department of Obstetrics and Gynecology, The First Affiliated Hospital of Soochow University, Suzhou, China. Electronic address: jsjhzh@126.com.

المصدر: Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy [Drug Resist Updat] 2024 May; Vol. 74, pp. 101077. Date of Electronic Publication: 2024 Mar 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Churchill Livingstone Country of Publication: Scotland NLM ID: 9815369 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2084 (Electronic) Linking ISSN: 13687646 NLM ISO Abbreviation: Drug Resist Updat Subsets: MEDLINE

مواضيع طبية MeSH: Ovarian Neoplasms*/drug therapy , Ovarian Neoplasms*/pathology , Ovarian Neoplasms*/genetics , Poly(ADP-ribose) Polymerase Inhibitors*/pharmacology , Protein Serine-Threonine Kinases*/antagonists & inhibitors , Protein Serine-Threonine Kinases*/metabolism , Protein Serine-Threonine Kinases*/genetics , Synthetic Lethal Mutations*/drug effects, Animals ; Female ; Humans ; Mice ; Apoptosis/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Mice, Nude ; Xenograft Model Antitumor Assays

المؤلفون: Ferretti S; Novartis BioMedical Research, Basel, Switzerland., Hamon J; Novartis BioMedical Research, Basel, Switzerland., de Kanter R; Novartis BioMedical Research, Basel, Switzerland., Scheufler C; Novartis BioMedical Research, Basel, Switzerland., Andraos-Rey R; Novartis BioMedical Research, Basel, Switzerland., Barbe S; Novartis BioMedical Research, Basel, Switzerland., Bechter E; Novartis BioMedical Research, Basel, Switzerland., Blank J; Novartis BioMedical Research, Basel, Switzerland., Bordas V; Novartis BioMedical Research, Basel, Switzerland., Dammassa E; Novartis BioMedical Research, Basel, Switzerland., Decker A; Novartis BioMedical Research, Basel, Switzerland., Di Nanni N; Novartis BioMedical Research, Basel, Switzerland., Dourdoigne M; Novartis BioMedical Research, Basel, Switzerland., Gavioli E; Novartis BioMedical Research, Basel, Switzerland.; Novartis Pharma AG, Basel, Switzerland., Hattenberger M; Novartis BioMedical Research, Basel, Switzerland., Heuser A; Novartis BioMedical Research, Basel, Switzerland., Hemmerlin C; Novartis BioMedical Research, Basel, Switzerland., Hinrichs J; Novartis BioMedical Research, Basel, Switzerland., Kerr G; Novartis BioMedical Research, Basel, Switzerland., Laborde L; Novartis BioMedical Research, Basel, Switzerland., Jaco I; Novartis BioMedical Research, Basel, Switzerland., Núñez EJ; Novartis BioMedical Research, Basel, Switzerland.; Pierre Fabre Laboratories, Toulouse, France., Martus HJ; Novartis BioMedical Research, Basel, Switzerland., Quadt C; Novartis BioMedical Research, Basel, Switzerland., Reschke M; Novartis BioMedical Research, Basel, Switzerland., Romanet V; Novartis BioMedical Research, Basel, Switzerland., Schaeffer F; Novartis BioMedical Research, Basel, Switzerland., Schoepfer J; Novartis BioMedical Research, Basel, Switzerland., Schrapp M; Novartis BioMedical Research, Basel, Switzerland., Strang R; Novartis BioMedical Research, Basel, Switzerland., Voshol H; Novartis BioMedical Research, Basel, Switzerland., Wartmann M; Novartis BioMedical Research, Basel, Switzerland., Welly S; Novartis BioMedical Research, Basel, Switzerland., Zécri F; Novartis BioMedical Research, Cambridge, MA, USA., Hofmann F; Novartis BioMedical Research, Basel, Switzerland.; Pierre Fabre Laboratories, Toulouse, France., Möbitz H; Novartis BioMedical Research, Basel, Switzerland. henrik.moebitz@novartis.com., Cortés-Cros M; Novartis BioMedical Research, Basel, Switzerland. marta.cortes-cros@novartis.com.

المصدر: Nature [Nature] 2024 May; Vol. 629 (8011), pp. 443-449. Date of Electronic Publication: 2024 Apr 24.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/adverse effects , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/therapeutic use , Drug Discovery* , Enzyme Inhibitors*/adverse effects , Enzyme Inhibitors*/chemistry , Enzyme Inhibitors*/pharmacology , Enzyme Inhibitors*/therapeutic use , Microsatellite Instability* , Neoplasms*/drug therapy , Neoplasms*/genetics , Neoplasms*/pathology , Neoplasms*/metabolism , Synthetic Lethal Mutations*/genetics , Werner Syndrome Helicase*/antagonists & inhibitors , Werner Syndrome Helicase*/genetics , Werner Syndrome Helicase*/metabolism, Animals ; Female ; Humans ; Mice ; Administration, Oral ; Allosteric Regulation/drug effects ; Cell Line, Tumor ; Clinical Trials as Topic ; Colorectal Neoplasms/drug therapy ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/pathology ; DNA Damage/drug effects ; Mice, Nude ; Protein Domains ; Reproducibility of Results ; Suppression, Genetic ; Tumor Suppressor Protein p53/metabolism ; Tumor Suppressor Protein p53/genetics ; Xenograft Model Antitumor Assays

المؤلفون: Lee ECY; Oncology R&D, AstraZeneca, Waltham, MA, USA., Reichl KD; Oncology R&D, AstraZeneca, Waltham, MA, USA., Gopalsamy A; Oncology R&D, AstraZeneca, Waltham, MA, USA.

المصدر: Expert opinion on therapeutic patents [Expert Opin Ther Pat] 2024 Apr; Vol. 34 (4), pp. 211-229. Date of Electronic Publication: 2024 May 20.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9516419 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7674 (Electronic) Linking ISSN: 13543776 NLM ISO Abbreviation: Expert Opin Ther Pat Subsets: MEDLINE

مواضيع طبية MeSH: Transcription Factors*/metabolism , Neoplasms*/drug therapy , Neoplasms*/pathology , Neoplasms*/genetics , Neoplasms*/metabolism , Nuclear Proteins*/metabolism , Nuclear Proteins*/antagonists & inhibitors , Patents as Topic* , Synthetic Lethal Mutations* , DNA Helicases*/metabolism , Antineoplastic Agents*/pharmacology, Humans ; Animals ; Proteolysis/drug effects ; Histone Acetyltransferases/metabolism ; Histone Acetyltransferases/antagonists & inhibitors ; Molecular Targeted Therapy

المؤلفون: Nguyen TT; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, USA., Torrini C; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, USA., Shang E; Department of Biological Sciences, Bronx Community College, City University of New York, New York, USA., Shu C; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, USA., Mun JY; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, USA., Gao Q; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, USA., Humala N; Department of Neurological Surgery, and., Akman HO; Department of Neurology, Columbia University Medical Center, New York, New York, USA., Zhang G; Proteomics and Metabolomics Core Facility, Weill Cornell Medicine, New York, New York, USA., Westhoff MA; Department of Pediatrics and Adolescent Medicine, and., Karpel-Massler G; Department of Neurosurgery, Ulm University Medical Center, Ulm, Germany., Bruce JN; Department of Neurological Surgery, and., Canoll P; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, USA., Siegelin MD; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, USA.

المصدر: JCI insight [JCI Insight] 2024 Mar 14; Vol. 9 (8). Date of Electronic Publication: 2024 Mar 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

مواضيع طبية MeSH: Aniline Compounds*/pharmacology , bcl-X Protein*/metabolism , bcl-X Protein*/genetics , Caprylates* , Glioblastoma*/pathology , Glioblastoma*/genetics , Glioblastoma*/metabolism , Glioblastoma*/drug therapy , Ketoglutarate Dehydrogenase Complex*/metabolism , Ketoglutarate Dehydrogenase Complex*/genetics , Ketoglutarate Dehydrogenase Complex*/antagonists & inhibitors , Sulfides* , Sulfonamides*/pharmacology , Synthetic Lethal Mutations* , Xenograft Model Antitumor Assays*, Animals ; Humans ; Mice ; Activating Transcription Factor 4/metabolism ; Activating Transcription Factor 4/genetics ; Brain Neoplasms/pathology ; Brain Neoplasms/metabolism ; Brain Neoplasms/genetics ; Brain Neoplasms/drug therapy ; Cell Line, Tumor ; Citric Acid Cycle/drug effects ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics

المؤلفون: Ren G; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China., Chen J; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.; Central laboratory, the Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China., Pu Y; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China., Yang EJ; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China., Tao S; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China., Mou PK; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China., Chen LJ; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China., Zhu W; Kiang Wu Hospital, Macau SAR, China., Chan KL; Kiang Wu Hospital, Macau SAR, China., Luo G; Kiang Wu Hospital, Macau SAR, China., Deng C; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.; MOE Frontiers Science Center for Precision Oncology, University of Macau, Taipa, Macau SAR, China., Shim JS; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.; MOE Frontiers Science Center for Precision Oncology, University of Macau, Taipa, Macau SAR, China.

المصدر: International journal of biological sciences [Int J Biol Sci] 2024 Mar 11; Vol. 20 (6), pp. 1978-1991. Date of Electronic Publication: 2024 Mar 11 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Ivyspring International Country of Publication: Australia NLM ID: 101235568 Publication Model: eCollection Cited Medium: Internet ISSN: 1449-2288 (Electronic) Linking ISSN: 14492288 NLM ISO Abbreviation: Int J Biol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Synthetic Lethal Mutations* , Colorectal Neoplasms*/drug therapy , Colorectal Neoplasms*/genetics, Humans ; Animals ; Mice ; Proto-Oncogene Proteins c-akt ; Phosphorylation ; Cytoplasm ; PTEN Phosphohydrolase/genetics

المؤلفون: Liu QW; Department of Pathology, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, Jiangsu Province 225300, China; General Surgery, Institute of Pancreatic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China., Yang ZW; Department of Pharmacy, Changning Maternity and Infant Health Hospital, East China Normal University, Shanghai, Shanghai 200050, China., Tang QH; Hunan Key Laboratory for Conservation and Utilization of Biological Resources in the Nanyue Mountainous Region and College of Life Sciences, Hengyang Normal University, Hengyang, Hunan Province 421008, China., Wang WE; General Surgery, the Fourth Hospital Of Changsha, Changsha Hospital Of Hunan Normal University, Changsha, Hunan Province 410006, China., Chu DS; Second Cadre Rest Medical and Health Center of Changning District, Shanghai Garrison, Shanghai226631, China., Ji JF; Department of Integrated Traditional Chinese and Western Internal Medicine, Affiliated Tumor Hospital of Nantong University, Nantong Tumor Hospital, Nantong, Jiangsu Province 226631, China., Fan QY; Institute of Oncology, Affiliated Tumor Hospital of Nantong University, Nantong, Jiangsu Province 226631, China., Jiang H; Department of Thoracic Surgery, the 905th Hospital of Chinese People's Liberation Army Navy, Shanghai 200050, China., Yang QX; Department of Pathology, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, Jiangsu Province 225300, China., Zhang H; Institute of Oncology, Affiliated Tumor Hospital of Nantong University, Nantong, Jiangsu Province 226631, China., Liu XY; Department of Pathology, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, Jiangsu Province 225300, China., Xu XS; Department of Obstetrics and Gynecology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China. Electronic address: xxs11830@rjh.com.cn., Wang XF; Department of Orthopedics, Xiamen Hospital, Zhongshan Hospital, Fudan University, Xiamen, Fujian Province 361015, China. Electronic address: wang.xiaofeng@zs-hospital.sh.cn., Liu JB; Institute of Oncology, Affiliated Tumor Hospital of Nantong University, Nantong, Jiangsu Province 226631, China. Electronic address: tians2008@ntu.edu.cn., Fu D; General Surgery, Institute of Pancreatic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China. Electronic address: fu800da900@126.com., Tao K; Department of Pathology, Tongji Hospital, School of Medicine, Tongji University, Shanghai 200065, China. Electronic address: protaokun@sina.com., Yu H; Department of Pathology, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, Jiangsu Province 225300, China; Department of Pathology, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, Jiangsu Province 225300, China. Electronic address: yuhong@njmu.edu.cn.

المصدر: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Mar; Vol. 172, pp. 116288. Date of Electronic Publication: 2024 Feb 20.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE

مواضيع طبية MeSH: Synthetic Lethal Mutations* , Neoplasms*/drug therapy , Neoplasms*/genetics, Cell Death ; DNA Repair

المؤلفون: Yin L; https://ror.org/04twxam07 Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Hu X; https://ror.org/04twxam07 Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; https://ror.org/04twxam07 Morgan Welch Inflammatory Breast Cancer Clinic and Research Program, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Pei G; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Center for Precision Health, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA., Tang M; https://ror.org/04twxam07 Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Zhou Y; https://ror.org/04twxam07 Department of Pediatrics Research, Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Zhang H; https://ror.org/04twxam07 Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Huang M; https://ror.org/04twxam07 Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Li S; https://ror.org/04twxam07 Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Zhang J; https://ror.org/04twxam07 Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Citu C; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Center for Precision Health, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA., Zhao Z; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Center for Precision Health, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA., Debeb BG; https://ror.org/04twxam07 Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; https://ror.org/04twxam07 Morgan Welch Inflammatory Breast Cancer Clinic and Research Program, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Feng X; https://ror.org/04twxam07 Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA fengxu@njmu.edu.cn.; Pancreas Center, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.; Pancreas Institute, Nanjing Medical University, Nanjing, China., Chen J; https://ror.org/04twxam07 Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA JChen8@mdanderson.org.

المصدر: Life science alliance [Life Sci Alliance] 2024 Feb 05; Vol. 7 (4). Date of Electronic Publication: 2024 Feb 05 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Life Science Alliance, LLC Country of Publication: United States NLM ID: 101728869 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2575-1077 (Electronic) Linking ISSN: 25751077 NLM ISO Abbreviation: Life Sci Alliance Subsets: MEDLINE

مواضيع طبية MeSH: bcl-X Protein*/genetics , bcl-X Protein*/metabolism , Breast Neoplasms*/genetics , Breast Neoplasms*/radiotherapy , Breast Neoplasms*/metabolism , Synthetic Lethal Mutations*/genetics, Female ; Humans ; Cell Line, Tumor ; Clustered Regularly Interspaced Short Palindromic Repeats/genetics ; NF-kappa B/genetics ; NF-kappa B/metabolism