المؤلفون: Chen HW; Institute of Biochemical Sciences, National Taiwan University, 10617 Taipei, Taiwan., Yeh HY; Institute of Biochemical Sciences, National Taiwan University, 10617 Taipei, Taiwan., Chang CC; Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, 100233 Taipei, Taiwan., Kuo WC; Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, 100233 Taipei, Taiwan., Lin SW; Institute of Biological Chemistry, Academia Sinica, 11529 Taipei, Taiwan., Vrielynck N; Université Paris-Saclay, INRAE, AgroParisTech, Institut Jean-Pierre Bourgin (IJPB), 78000,Versailles, France., Grelon M; Université Paris-Saclay, INRAE, AgroParisTech, Institut Jean-Pierre Bourgin (IJPB), 78000,Versailles, France., Chan NL; Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, 100233 Taipei, Taiwan., Chi P; Institute of Biochemical Sciences, National Taiwan University, 10617 Taipei, Taiwan.; Institute of Biological Chemistry, Academia Sinica, 11529 Taipei, Taiwan.

المصدر: Nucleic acids research [Nucleic Acids Res] 2024 May 08; Vol. 52 (8), pp. 4541-4555.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: Arabidopsis*/genetics , Arabidopsis*/enzymology , Arabidopsis*/metabolism , Arabidopsis Proteins*/metabolism , Arabidopsis Proteins*/genetics , DNA Topoisomerases, Type II*/metabolism, Adenosine Triphosphate/metabolism ; Archaeal Proteins ; DNA Breaks, Double-Stranded ; DNA Topoisomerases/metabolism ; DNA Topoisomerases/genetics ; DNA-Binding Proteins/metabolism ; DNA-Binding Proteins/genetics ; Endodeoxyribonucleases/metabolism ; Endodeoxyribonucleases/genetics ; Endodeoxyribonucleases/chemistry ; Evolution, Molecular ; Meiosis ; Protein Multimerization

المؤلفون: Lee J; Physics Department & LASSP, Cornell University, Ithaca, NY, 14853, USA., Wu M; Physics Department & LASSP, Cornell University, Ithaca, NY, 14853, USA.; Howard Hughes Medical Institute, Cornell University, Ithaca, NY, 14853, USA., Inman JT; Physics Department & LASSP, Cornell University, Ithaca, NY, 14853, USA.; Howard Hughes Medical Institute, Cornell University, Ithaca, NY, 14853, USA., Singh G; Biophysics Program, Cornell University, Ithaca, NY, 14853, USA., Park SH; Biophysics Program, Cornell University, Ithaca, NY, 14853, USA., Lee JH; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Fulbright RM; Physics Department & LASSP, Cornell University, Ithaca, NY, 14853, USA., Hong Y; Department of Electrical and Computer Engineering, Cornell University, Ithaca, NY, 14853, USA., Jeong J; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Berger JM; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Wang MD; Physics Department & LASSP, Cornell University, Ithaca, NY, 14853, USA. mwang@physics.cornell.edu.; Howard Hughes Medical Institute, Cornell University, Ithaca, NY, 14853, USA. mwang@physics.cornell.edu.

المصدر: Nature communications [Nat Commun] 2023 Oct 27; Vol. 14 (1), pp. 6844. Date of Electronic Publication: 2023 Oct 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: DNA Topoisomerases, Type II*/metabolism , DNA*, Chromatin ; DNA Topoisomerases, Type I/metabolism ; Eukaryotic Cells/metabolism

المؤلفون: Cuarenta A; Department of Psychology, University of Wisconsin-Madison, United States. Electronic address: cuarenta@wisc.edu., Kigar SL; Molecular and Cellular Pharmacology Training Program, University of Wisconsin-Madison, United States., Keese AP; Department of Psychology, University of Wisconsin-Madison, United States., Guagliardo SE; Department of Psychology, University of Wisconsin-Madison, United States., Chang L; Department of Psychology, University of Wisconsin-Madison, United States., Bakshi VP; Department of Psychiatry, University of Wisconsin-Madison, United States; Neuroscience Training Program, University of Wisconsin-Madison, United States., Auger AP; Department of Psychology, University of Wisconsin-Madison, United States; Neuroscience Training Program, University of Wisconsin-Madison, United States. Electronic address: apauger@wisc.edu.

المصدر: Brain research [Brain Res] 2023 Jun 15; Vol. 1809, pp. 148339. Date of Electronic Publication: 2023 Mar 24.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 0045503 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6240 (Electronic) Linking ISSN: 00068993 NLM ISO Abbreviation: Brain Res Subsets: MEDLINE

مواضيع طبية MeSH: DNA Topoisomerases, Type I*/chemistry , DNA Topoisomerases, Type I*/genetics , DNA Topoisomerases, Type I*/metabolism , Stress, Psychological*/metabolism, Animals ; Female ; Male ; Rats ; Brain/metabolism ; DNA ; DNA Topoisomerases/metabolism

المؤلفون: Jian JY; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA., Osheroff N; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.; Department of Medicine (Hematology/Oncology), Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2023 Jul 07; Vol. 24 (13). Date of Electronic Publication: 2023 Jul 07.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: DNA Topoisomerases, Type II*/metabolism , Functional Laterality*, Humans ; DNA ; Isomerases/genetics ; DNA Replication ; DNA Topoisomerases, Type I/metabolism

المؤلفون: Vidmar V; Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg, CNRS UMR 7104, Inserm U 1258, 67400 Illkirch, France., Vayssières M; Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg, CNRS UMR 7104, Inserm U 1258, 67400 Illkirch, France., Lamour V; Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg, CNRS UMR 7104, Inserm U 1258, 67400 Illkirch, France.; Hôpitaux Universitaires de Strasbourg, 67098 Strasbourg, France.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 16; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 16.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: DNA Topoisomerases*/metabolism , DNA*/chemistry, Isomerases/metabolism ; Catalytic Domain ; DNA Topoisomerases, Type I/metabolism ; DNA Topoisomerases, Type II/metabolism

المؤلفون: Chen YX; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, People's Republic of China., Wu S; Department of Medicinal Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai, 200433, People's Republic of China., Shen X; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, People's Republic of China., Xu DF; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, People's Republic of China., Wang Q; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, People's Republic of China., Ji SH; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, People's Republic of China., Zhu H; Key Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang Province, School of Medicine, Hangzhou City University, Hangzhou, 310015, Zhejiang Province, China., Wu G; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, People's Republic of China., Sheng C; Department of Medicinal Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai, 200433, People's Republic of China., Cai YR; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, People's Republic of China.

المصدر: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2024 Jul 11; Vol. 30 (39), pp. e202401400. Date of Electronic Publication: 2024 Jun 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9513783 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3765 (Electronic) Linking ISSN: 09476539 NLM ISO Abbreviation: Chemistry Subsets: MEDLINE

مواضيع طبية MeSH: Topoisomerase I Inhibitors*/chemistry , Topoisomerase I Inhibitors*/pharmacology , Topoisomerase I Inhibitors*/chemical synthesis , DNA Topoisomerases, Type I*/metabolism , DNA Topoisomerases, Type I*/chemistry , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemical synthesis , Coumarins*/chemistry , Coumarins*/pharmacology, Humans ; Structure-Activity Relationship ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Oxidation-Reduction ; Umbelliferones/chemistry ; Umbelliferones/pharmacology ; Drug Screening Assays, Antitumor

المؤلفون: Amoiridis M; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Brighton, BN1 9RH, UK.; Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France.; Institut National de la Santé et de la Recherche Médicale (INSERM), U1258, Illkirch, France.; Centre National de Recherche Scientifique (CNRS), UMR7104, Illkirch, France.; Université de Strasbourg, Illkirch, France., Verigos J; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Brighton, BN1 9RH, UK., Meaburn K; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Brighton, BN1 9RH, UK., Gittens WH; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Brighton, BN1 9RH, UK., Ye T; Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France.; Institut National de la Santé et de la Recherche Médicale (INSERM), U1258, Illkirch, France.; Centre National de Recherche Scientifique (CNRS), UMR7104, Illkirch, France.; Université de Strasbourg, Illkirch, France., Neale MJ; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Brighton, BN1 9RH, UK., Soutoglou E; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Brighton, BN1 9RH, UK. E.Soutoglou@sussex.ac.uk.

المصدر: Nature communications [Nat Commun] 2024 Jul 08; Vol. 15 (1), pp. 5727. Date of Electronic Publication: 2024 Jul 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: DNA Topoisomerases, Type II*/metabolism , DNA Topoisomerases, Type II*/genetics , Heterochromatin*/metabolism, Animals ; Topoisomerase II Inhibitors/pharmacology ; Repetitive Sequences, Nucleic Acid/genetics ; Poly-ADP-Ribose Binding Proteins/metabolism ; Poly-ADP-Ribose Binding Proteins/genetics ; DNA Replication ; DNA, Superhelical/metabolism ; DNA, Superhelical/chemistry ; Humans ; Mice ; DNA-Binding Proteins/metabolism ; DNA-Binding Proteins/genetics ; DNA/metabolism ; DNA/chemistry ; Interphase

المؤلفون: Grammatikaki S; Laboratory of Biology, Medical School, National and Kapodistrian University of Athens, Athens, Greece., Bala VM; Hygeia Hospital, Marousi, Greece., Katifelis H; Laboratory of Biology, Medical School, National and Kapodistrian University of Athens, Athens, Greece., Lampropoulou DI; ECONCARE, Athens, Greece., Mukha I; Chuiko Institute of Surface Chemistry, National Academy of Sciences of Ukraine, Kyiv, Ukraine., Vityuk N; Chuiko Institute of Surface Chemistry, National Academy of Sciences of Ukraine, Kyiv, Ukraine., Lagopati N; Laboratory of Biology, Medical School, National and Kapodistrian University of Athens, Athens, Greece., Kouloulias V; Radiation Oncology Unit, 2nd Department of Radiology, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece., Aravantinos G; Euroclinic, Athens, Greece., Gazouli M; Laboratory of Biology, Medical School, National and Kapodistrian University of Athens, Athens, Greece; mgazouli@med.uoa.gr.

المصدر: In vivo (Athens, Greece) [In Vivo] 2024 Jul-Aug; Vol. 38 (4), pp. 1665-1670.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: International Institute of Anticancer Research Country of Publication: Greece NLM ID: 8806809 Publication Model: Print Cited Medium: Internet ISSN: 1791-7549 (Electronic) Linking ISSN: 0258851X NLM ISO Abbreviation: In Vivo Subsets: MEDLINE

مواضيع طبية MeSH: Breast Neoplasms*/genetics , Breast Neoplasms*/pathology , Breast Neoplasms*/metabolism , Breast Neoplasms*/drug therapy , DNA Topoisomerases, Type II*/metabolism , DNA Topoisomerases, Type II*/genetics , Cell Proliferation*/drug effects , Hyperthermia, Induced*/methods , Ki-67 Antigen*/metabolism , Ki-67 Antigen*/genetics , Microtubule-Associated Proteins*/genetics , Microtubule-Associated Proteins*/metabolism , Cell Cycle Proteins*/genetics , Cell Cycle Proteins*/metabolism , Poly-ADP-Ribose Binding Proteins*/genetics , Poly-ADP-Ribose Binding Proteins*/metabolism, Humans ; Cell Line, Tumor ; Female ; HEK293 Cells ; Gene Expression Regulation, Neoplastic/drug effects ; Biomarkers, Tumor/metabolism ; Biomarkers, Tumor/genetics

المؤلفون: Wang X; Division of Pharmaceutics and Pharmacology, College of Pharmacy (X.W., J.C.-M., X.Z., V.A.H., J.C.Y., T.S.E.) and Division of Outcomes and Translational Science (J.L.), The Ohio State University, Columbus, Ohio., Carvajal-Moreno J; Division of Pharmaceutics and Pharmacology, College of Pharmacy (X.W., J.C.-M., X.Z., V.A.H., J.C.Y., T.S.E.) and Division of Outcomes and Translational Science (J.L.), The Ohio State University, Columbus, Ohio., Zhao X; Division of Pharmaceutics and Pharmacology, College of Pharmacy (X.W., J.C.-M., X.Z., V.A.H., J.C.Y., T.S.E.) and Division of Outcomes and Translational Science (J.L.), The Ohio State University, Columbus, Ohio., Li J; Division of Pharmaceutics and Pharmacology, College of Pharmacy (X.W., J.C.-M., X.Z., V.A.H., J.C.Y., T.S.E.) and Division of Outcomes and Translational Science (J.L.), The Ohio State University, Columbus, Ohio., Hernandez VA; Division of Pharmaceutics and Pharmacology, College of Pharmacy (X.W., J.C.-M., X.Z., V.A.H., J.C.Y., T.S.E.) and Division of Outcomes and Translational Science (J.L.), The Ohio State University, Columbus, Ohio., Yalowich JC; Division of Pharmaceutics and Pharmacology, College of Pharmacy (X.W., J.C.-M., X.Z., V.A.H., J.C.Y., T.S.E.) and Division of Outcomes and Translational Science (J.L.), The Ohio State University, Columbus, Ohio yalowich.1@osu.edu elton.8@osu.edu., Elton TS; Division of Pharmaceutics and Pharmacology, College of Pharmacy (X.W., J.C.-M., X.Z., V.A.H., J.C.Y., T.S.E.) and Division of Outcomes and Translational Science (J.L.), The Ohio State University, Columbus, Ohio yalowich.1@osu.edu elton.8@osu.edu.

المصدر: Molecular pharmacology [Mol Pharmacol] 2024 Jun 18; Vol. 106 (1), pp. 33-46. Date of Electronic Publication: 2024 Jun 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0035623 Publication Model: Electronic Cited Medium: Internet ISSN: 1521-0111 (Electronic) Linking ISSN: 0026895X NLM ISO Abbreviation: Mol Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Etoposide*/pharmacology , DNA Topoisomerases, Type II*/genetics , DNA Topoisomerases, Type II*/metabolism , Drug Resistance, Neoplasm*/genetics , Drug Resistance, Neoplasm*/drug effects , Polyadenylation*/drug effects , Polyadenylation*/genetics , Introns*/genetics, Humans ; K562 Cells ; CRISPR-Cas Systems

المؤلفون: Evoli S; Department of Physics, Illinois Institute of Technology, Chicago, Illinois; Center for Molecular Study of Condensed Soft Matter, Illinois Institute of Technology, Chicago, Illinois., Kariyawasam NL; Department of Physics, Illinois Institute of Technology, Chicago, Illinois; Center for Molecular Study of Condensed Soft Matter, Illinois Institute of Technology, Chicago, Illinois., Nitiss KC; Pharmaceutical Sciences Department, University of Illinois at Chicago, Rockford, Illinois., Nitiss JL; Pharmaceutical Sciences Department, University of Illinois at Chicago, Rockford, Illinois., Wereszczynski J; Department of Physics, Illinois Institute of Technology, Chicago, Illinois; Center for Molecular Study of Condensed Soft Matter, Illinois Institute of Technology, Chicago, Illinois; Department of Biology, Illinois Institute of Technology, Chicago, Illinois. Electronic address: jwereszc@iit.edu.

المصدر: Biophysical journal [Biophys J] 2024 Jun 18; Vol. 123 (12), pp. 1620-1634. Date of Electronic Publication: 2024 May 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0370626 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1542-0086 (Electronic) Linking ISSN: 00063495 NLM ISO Abbreviation: Biophys J Subsets: MEDLINE

مواضيع طبية MeSH: DNA Topoisomerases, Type II*/metabolism , DNA Topoisomerases, Type II*/chemistry , DNA Topoisomerases, Type II*/genetics , Molecular Dynamics Simulation*, Allosteric Regulation ; Saccharomyces cerevisiae/enzymology ; Saccharomyces cerevisiae/metabolism ; Protein Domains ; Models, Molecular