نتائج البحث - "topoizomeraza IV"

1

Amide containing NBTI antibacterials with reduced hERG inhibition, retained antimicrobial activity against gram-positive bacteria and in vivo efficacy

المؤلفون: Maja Kokot, Matjaž Weiss, Irena Zdovc, Lidija Senerovic, Natasa Radakovic, Marko Anderluh, Nikola Minovski, Martina Hrast

المصدر: European journal of medicinal chemistry, str. 1-13 : Ilustr., Vol. 250, 2023
COBISS-ID: 25429760
European journal of medicinal chemistry, vol. 115160, no. 250, pp. 1-13, 2023.

وصف الملف: application/pdf; text/url

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::007423b60ee74c7daa799df830c48ced
https://plus.cobiss.net/cobiss/si/en/bib/141418755

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2

New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureus

المساهمون: Medicinal chemistry, AIMMS

المصدر: Durcik, M, Cotman, A E, Toplak, Ž, Možina, Š, Skok, Ž, Szili, P E, Czikkely, M, Maharramov, E, Vu, T H, Piras, M V, Zidar, N, Ilaš, J, Zega, A, Trontelj, J, Pardo, L A, Hughes, D, Huseby, D, Berruga-Fernández, T, Cao, S, Simoff, I, Svensson, R, Korol, S V, Jin, Z, Vicente, F, Ramos, M C, Mundy, J E A, Maxwell, A, Stevenson, C E M, Lawson, D M, Glinghammar, B, Sjöström, E, Bohlin, M, Oreskär, J, Alvér, S, Janssen, G V, Sterk, G J, Kikelj, D, Pal, C, Tomašič, T & Peterlin Mašič, L 2023, ' New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureus ', Journal of medicinal chemistry, vol. 66, no. 6, pp. 3968-3994 . https://doi.org/10.1021/acs.jmedchem.2c01905
Journal of medicinal chemistry, 66(6), 3968-3994. American Chemical Society
Journal of Medicinal Chemistry
Journal of medicinal chemistry, str. 3968-3994 : Ilustr., Vol. 66, iss. 6, 2023
COBISS-ID: 512806681
Journal of medicinal chemistry, vol. 66, no. 6, pp. 3968-3994, 2023.

مصطلحات موضوعية: Infectious Medicine, topoizomeraza IV, bakterijska rezistenca, nanomolarni inhibitorji benzotiazola, Farmacevtska kemija, Infektionsmedicin, peptides and proteins, antibakterijsko delovanje, zaviralci, nanomolarni inhibitorji benzotiazola, topoizomeraza IV, Microbiology in the medical area, Bakterije, antibacterial activity, SDG 3 - Good Health and Well-being, inhibitors, Drug Discovery, Mikrobiologi inom det medicinska området, genetics, antibakterijsko delovanje, bacteria, zaviralci, Bakterijska rezistenca, Läkemedelskemi, antibacterial activity, bacteria, inhibitors, udc:615, inhibition, bakterije, farmacevtska kemija, Molecular Medicine, Medicinal Chemistry, udc:615.015.8

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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c3d01f7594899ad1504d0f95893f77
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-501871

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3

Novi dvojni zaviralci DNA-giraze in topoizomeraze IV z delovanjem na odporne bakterijske seve in z nizkim tveganjem za razvoj odpornosti

المؤلفون: Durcik, Martina

المساهمون: Peterlin Mašič, Lucija

مصطلحات موضوعية: topoizomeraza IV, antibacterial activity, dvojni zaviralci, topoisomerase IV, protibakterijsko delovanje, DNA gyrase, Benzotiazol, DNA-giraza, Benzothiazole, bacterial resistance, bakterijska odpornost, dual inhibitors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______3505::cc8d28d5e2f3fc51d0b395b64a68cc7d
https://repozitorij.uni-lj.si/Dokument.php?id=167776&dn=

4

Razvoj odnosa med strukturo in delovanjem pri novih zaviralcih bakterijskih topoizomeraz

المؤلفون: Baš, Jakob

المساهمون: Anderluh, Marko

مصطلحات موضوعية: desni del, NBTI, distančnik, DNA gyrase, Topoisomerase IV, DNA-giraza, right-hand side, linker, Topoizomeraza IV

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______3505::c7cb76537c5dfc3acf275a4bf948e6dd
https://repozitorij.uni-lj.si/Dokument.php?id=164891&dn=

5

Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors

المؤلفون: Cristina D. Cruz, Danijel Kikelj, Michaela Barančoková, Ondřej Benek, Clare E. M. Stevenson, Päivi Tammela, Tihomir Tomašič, Lucija Peterlin Mašič, Janez Ilaš, Žiga Skok, Anamarija Zega, Nace Zidar, David M. Lawson, Anthony Maxwell, Julia E. A. Mundy

المساهمون: Division of Pharmaceutical Biosciences, Bioactivity Screening Group, Drug Research Program, Divisions of Faculty of Pharmacy, Global Development Studies, Helsinki Institute of Sustainability Science (HELSUS), University of Helsinki, Division of Pharmaceutical Biosciences, University of Helsinki, Global Development Studies

المصدر: ACS Medicinal Chemistry Letters
ACS medicinal chemistry letters, vol. 11, no. 12, pp. 2433-2440, 2020.
ACS Medicinal Chemistry Letters, str. 2433-2440 : Ilustr., Vol. 11, iss. 12, 2020
COBISS-ID: 2959217

مصطلحات موضوعية: topoizomeraza IV, Letter, N-PHENYLINDOLAMIDES, Topoisomerase IV, Stereochemistry, ANTIBACTERIAL ACTIVITY, Farmacevtska kemija, Bacterial enzymes, 01 natural sciences, Biochemistry, DNA gyrase, topoizomeraza IV, giraza DNA, antibakterijski benzotiazol, inibitorji giraze B, AMYCOLAMICIN, DNA Topoisomerase IV, chemistry.chemical_compound, udc:615.4:54, topoisomerase IV, Drug Discovery, ParE, udc:615.4, GyrB, CHALLENGES, biology, 010405 organic chemistry, Drug discovery, Chemistry, DNA gyrase, topoisomerase IV, GyrB, ParE, antibacterial benzothiazole, Organic Chemistry, antibakterijski benzotiazol, giraza DNA, benzothiazole, KIBDELOMYCIN, antibacterial benzothiazole, N-PHENYL-4,5-DIBROMOPYRROLAMIDES, Chemical space, TRANSLOCATION, 0104 chemical sciences, antibacterial, 010404 medicinal & biomolecular chemistry, Benzothiazole, 317 Pharmacy, inibitorji giraze B, biology.protein, Antibacterial activity, ATPASE INHIBITORS, RESISTANCE