المؤلفون: Sanders K; Biochemical Genetics Laboratory, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, United States of America., Peck D; Biochemical Genetics Laboratory, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, United States of America., Bentz Pino G; Biochemical Genetics Laboratory, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, United States of America., Studinski Jones A; Biochemical Genetics Laboratory, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, United States of America., White A; Biochemical Genetics Laboratory, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, United States of America., Gavrilov D; Biochemical Genetics Laboratory, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, United States of America., Matern D; Biochemical Genetics Laboratory, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, United States of America., Oglesbee D; Biochemical Genetics Laboratory, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, United States of America., Schultz M; Biochemical Genetics Laboratory, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, United States of America., Tortorelli S; Biochemical Genetics Laboratory, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, United States of America., Hall PL; Biochemical Genetics Laboratory, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, United States of America. Electronic address: hall.patricia@mayo.edu.

المصدر: Molecular genetics and metabolism [Mol Genet Metab] 2024 May; Vol. 142 (1), pp. 108455. Date of Electronic Publication: 2024 Mar 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 9805456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-7206 (Electronic) Linking ISSN: 10967192 NLM ISO Abbreviation: Mol Genet Metab Subsets: MEDLINE

مواضيع طبية MeSH: Creatine*/*deficiency , Plasma Membrane Neurotransmitter Transport Proteins*/*deficiency, Creatine*/blood , Creatine*/urine , Creatinine*/blood , Creatinine*/urine , Plasma Membrane Neurotransmitter Transport Proteins*/genetics , Plasma Membrane Neurotransmitter Transport Proteins*/blood , Mental Retardation, X-Linked*/genetics , Mental Retardation, X-Linked*/blood , Mental Retardation, X-Linked*/diagnosis , Brain Diseases, Metabolic, Inborn*, Humans ; Male ; Female ; Child ; Child, Preschool ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/blood ; Nerve Tissue Proteins/deficiency ; Infant ; Adolescent ; Membrane Transport Proteins/genetics ; Membrane Transport Proteins/deficiency ; Membrane Transport Proteins/blood ; Adult

SCR Disease Name: Creatine deficiency, X-linked

المؤلفون: Coban I; Abteilung für Molekulare Genetik, Institut für Mikrobiologie und Genetik, Göttinger Zentrum für Molekulare Biowissenschaften (GZMB), Georg-August Universität Göttingen, Göttingen, Germany., Lamping JP; Abteilung für Molekulare Genetik, Institut für Mikrobiologie und Genetik, Göttinger Zentrum für Molekulare Biowissenschaften (GZMB), Georg-August Universität Göttingen, Göttingen, Germany., Hirsch AG; Abteilung für Molekulare Genetik, Institut für Mikrobiologie und Genetik, Göttinger Zentrum für Molekulare Biowissenschaften (GZMB), Georg-August Universität Göttingen, Göttingen, Germany., Wasilewski S; Abteilung für Molekulare Genetik, Institut für Mikrobiologie und Genetik, Göttinger Zentrum für Molekulare Biowissenschaften (GZMB), Georg-August Universität Göttingen, Göttingen, Germany., Shomroni O; NGS-Integrative Genomics Core Unit, Institute of Pathology, University Medical Center Göttingen, Göttingen, Germany., Giesbrecht O; Abteilung für Molekulare Genetik, Institut für Mikrobiologie und Genetik, Göttinger Zentrum für Molekulare Biowissenschaften (GZMB), Georg-August Universität Göttingen, Göttingen, Germany., Salinas G; NGS-Integrative Genomics Core Unit, Institute of Pathology, University Medical Center Göttingen, Göttingen, Germany., Krebber H; Abteilung für Molekulare Genetik, Institut für Mikrobiologie und Genetik, Göttinger Zentrum für Molekulare Biowissenschaften (GZMB), Georg-August Universität Göttingen, Göttingen, Germany. heike.krebber@biologie.uni-goettingen.de.

المصدر: Nature [Nature] 2024 Jul; Vol. 631 (8020), pp. 432-438. Date of Electronic Publication: 2024 Jun 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Active Transport, Cell Nucleus* , Cell Nucleus*/metabolism , Gene Expression Regulation, Fungal* , RNA Transport* , RNA, Antisense*/metabolism , RNA, Antisense*/genetics , RNA, Double-Stranded*/metabolism , RNA, Double-Stranded*/genetics , RNA, Messenger*/metabolism , RNA, Messenger*/genetics , Saccharomyces cerevisiae*/genetics , Saccharomyces cerevisiae*/metabolism, Cytoplasm/metabolism ; DEAD-box RNA Helicases/metabolism ; DEAD-box RNA Helicases/genetics ; Nucleocytoplasmic Transport Proteins/metabolism ; Nucleocytoplasmic Transport Proteins/genetics ; RNA-Binding Proteins/metabolism ; RNA-Binding Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Saccharomyces cerevisiae Proteins/genetics

المؤلفون: von Känel C; Department of Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern, Bern, Switzerland., Oeljeklaus S; Faculty of Chemistry and Pharmacy, Biochemistry II, Theodor Boveri-Institute, University of Würzburg, Würzburg, Germany., Wenger C; Department of Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern, Bern, Switzerland., Stettler P; Department of Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern, Bern, Switzerland., Harsman A; Department of Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern, Bern, Switzerland., Warscheid B; Faculty of Chemistry and Pharmacy, Biochemistry II, Theodor Boveri-Institute, University of Würzburg, Würzburg, Germany., Schneider A; Department of Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern, Bern, Switzerland.

المصدر: Molecular microbiology [Mol Microbiol] 2024 Jun; Vol. 121 (6), pp. 1112-1126. Date of Electronic Publication: 2024 Apr 15.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 8712028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2958 (Electronic) Linking ISSN: 0950382X NLM ISO Abbreviation: Mol Microbiol Subsets: MEDLINE

مواضيع طبية MeSH: Trypanosoma brucei brucei*/metabolism , Trypanosoma brucei brucei*/genetics , Trypanosoma brucei brucei*/enzymology , Protozoan Proteins*/metabolism , Protozoan Proteins*/genetics , Mitochondrial Membranes*/metabolism , Protein Transport* , Mitochondria*/metabolism , Mitochondrial Membrane Transport Proteins*/metabolism , Mitochondrial Membrane Transport Proteins*/genetics, Mitochondrial Precursor Protein Import Complex Proteins ; Mitochondrial Proteins/metabolism ; Mitochondrial Proteins/genetics ; Membrane Transport Proteins/metabolism ; Membrane Transport Proteins/genetics ; Protein Subunits/metabolism

المؤلفون: Fujita S; Laboratory of Fermentation Microbiology, Department of Agricultural Chemistry, Graduate School of Agricultural Science, Tohoku University, Aoba, Aramaki, Aoba-ku, Sendai, Japan., Tada H; Laboratory of Fungal Biotechnology, Department of Agricultural Chemistry, Graduate School of Agricultural Science, Tohoku University, Aoba, Aramaki, Aoba-ku, Sendai, Japan., Matsuura Y; Laboratory of Fungal Biotechnology, Department of Agricultural Chemistry, Graduate School of Agricultural Science, Tohoku University, Aoba, Aramaki, Aoba-ku, Sendai, Japan., Hiramoto T; Laboratory of Fungal Biotechnology, Department of Agricultural Chemistry, Graduate School of Agricultural Science, Tohoku University, Aoba, Aramaki, Aoba-ku, Sendai, Japan., Tanaka M; Department of Applied Biological Chemistry, Graduate School of Agricultural Science, Tokyo University of Agriculture and Technology, Fuchu, Tokyo, Japan., Shintani T; Laboratory of Fungal Biotechnology, Department of Agricultural Chemistry, Graduate School of Agricultural Science, Tohoku University, Aoba, Aramaki, Aoba-ku, Sendai, Japan., Gomi K; Laboratory of Fermentation Microbiology, Department of Agricultural Chemistry, Graduate School of Agricultural Science, Tohoku University, Aoba, Aramaki, Aoba-ku, Sendai, Japan. Electronic address: katsuya.gomi.a6@tohoku.ac.jp.

المصدر: Fungal genetics and biology : FG & B [Fungal Genet Biol] 2024 Aug; Vol. 173, pp. 103909. Date of Electronic Publication: 2024 Jun 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 9607601 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0937 (Electronic) Linking ISSN: 10871845 NLM ISO Abbreviation: Fungal Genet Biol Subsets: MEDLINE

مواضيع طبية MeSH: Aspergillus oryzae*/genetics , Aspergillus oryzae*/metabolism , Aspergillus oryzae*/enzymology , Ubiquitination* , Glucose*/metabolism , Endocytosis*/drug effects , Fungal Proteins*/metabolism , Fungal Proteins*/genetics , Ubiquitin-Protein Ligases*/metabolism , Ubiquitin-Protein Ligases*/genetics , Monosaccharide Transport Proteins*/genetics , Monosaccharide Transport Proteins*/metabolism, Maltose/metabolism ; Proteolysis ; Gene Expression Regulation, Fungal/drug effects ; Membrane Transport Proteins/metabolism ; Membrane Transport Proteins/genetics

المؤلفون: Schneider S; Department of Structural Biology, Max Planck Institute of Biophysics, 60438 Frankfurt am Main, Germany., Kühlbrandt W; Department of Structural Biology, Max Planck Institute of Biophysics, 60438 Frankfurt am Main, Germany., Yildiz Ö; Department of Structural Biology, Max Planck Institute of Biophysics, 60438 Frankfurt am Main, Germany; Structural Biology Unit, Max Planck Institute of Biophysics, 60438 Frankfurt am Main, Germany. Electronic address: Oezkan.Yildiz@biophys.mpg.de.

المصدر: Structure (London, England : 1993) [Structure] 2024 Jul 11; Vol. 32 (7), pp. 979-988.e4. Date of Electronic Publication: 2024 Apr 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4186 (Electronic) Linking ISSN: 09692126 NLM ISO Abbreviation: Structure Subsets: MEDLINE

مواضيع طبية MeSH: Saccharomyces cerevisiae Proteins*/metabolism , Saccharomyces cerevisiae Proteins*/chemistry , Phosphates*/metabolism , Phosphates*/chemistry , Saccharomyces cerevisiae*/metabolism , Cryoelectron Microscopy* , Phosphate Transport Proteins*/metabolism , Phosphate Transport Proteins*/chemistry , Models, Molecular*, Binding Sites ; Protein Binding ; Biological Transport

المؤلفون: Dai F; Department of Parasitology, School of Biology and Basic Medical Sciences, MOE Key Laboratory of Geriatric Diseases and Immunology, Suzhou Key Laboratory of Pathogen Bioscience and Anti-infective Medicine, Suzhou Medical College, Soochow University, Suzhou, China.; Department of Medical Sciences, Chung-Ang University College of Medicine, Seoul, Republic of Korea., Lee SO; Department of Medical Sciences, Chung-Ang University College of Medicine, Seoul, Republic of Korea.; Department of Medical Zoology and Medical Research Center for Bioreaction to Reactive Oxygen Species and Biomedical Science Institute, School of Medicine, Graduate School, Kyung Hee University, Seoul, Republic of Korea., Song JH; Department of Pharmacology, Chung-Ang University College of Medicine, Seoul, Republic of Korea., Yoo WG; Department of Medical Sciences, Chung-Ang University College of Medicine, Seoul, Republic of Korea.; Laboratory of Veterinary Parasitology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, Republic of Korea., Shin EH; Department of Tropical Medicine and Parasitology, Seoul National University College of Medicine, and Institute of Endemic Diseases, Seoul, Republic of Korea.; Seoul National University Bundang Hospital, Seongnam, Republic of Korea., Bai X; Department of Medical Sciences, Chung-Ang University College of Medicine, Seoul, Republic of Korea.; Medical Research Center, Binzhou Medical University Hospital, Binzhou, China., Hong SJ; Department of Medical Sciences, Chung-Ang University College of Medicine, Seoul, Republic of Korea.; Center for Infectious Vectors and Diseases, Incheon National University, Incheon, Republic of Korea.

المصدر: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 Jul 05; Vol. 18 (7), pp. e0012315. Date of Electronic Publication: 2024 Jul 05 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

مواضيع طبية MeSH: Clonorchis sinensis*/metabolism , Clonorchis sinensis*/genetics , Glucose*/metabolism , Sodium-Glucose Transport Proteins*/metabolism , Sodium-Glucose Transport Proteins*/genetics , Glucose Transport Proteins, Facilitative*/metabolism , Glucose Transport Proteins, Facilitative*/genetics, Animals ; Clonorchiasis/parasitology ; Biological Transport

المؤلفون: Hua X; Key Laboratory of Environmental Medicine Engineering of Ministry of Education, Medical School, Southeast University, Nanjing 210009, China., Liang G; School of Public Health, Southeast University, Nanjing 210009, China., Chao J; Key Laboratory of Environmental Medicine Engineering of Ministry of Education, Medical School, Southeast University, Nanjing 210009, China., Wang D; Key Laboratory of Environmental Medicine Engineering of Ministry of Education, Medical School, Southeast University, Nanjing 210009, China; Shenzhen Ruipuxun Academy for Stem Cell & Regenerative Medicine, Shenzhen, China. Electronic address: dayongw@seu.edu.cn.

المصدر: Journal of hazardous materials [J Hazard Mater] 2024 Jul 05; Vol. 472, pp. 134598. Date of Electronic Publication: 2024 May 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9422688 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3336 (Electronic) Linking ISSN: 03043894 NLM ISO Abbreviation: J Hazard Mater Subsets: MEDLINE

مواضيع طبية MeSH: Caenorhabditis elegans*/drug effects , Longevity*/drug effects , Caenorhabditis elegans Proteins*/genetics , Caenorhabditis elegans Proteins*/metabolism , Mitochondria*/drug effects , Mitochondria*/metabolism , Electron Transport Complex I*/metabolism , Electron Transport Complex I*/genetics, Animals ; Electron Transport Complex II/metabolism ; Electron Transport Complex II/genetics ; Insulin/metabolism ; Adenosine Triphosphate/metabolism ; Reactive Oxygen Species/metabolism ; NADH Dehydrogenase ; Cytochromes b

المؤلفون: Liu L; Department of Respiratory and Critical Care Medicine, Wuxi Ninth People's Hospital Affiliated to Soochow University, Wuxi, Jiangsu, China., Zhang Y; Department of Respiratory and Critical Care Medicine, Wuxi Ninth People's Hospital Affiliated to Soochow University, Wuxi, Jiangsu, China; zy_zy1010@163.com., Xu D; Department of Respiratory and Critical Care Medicine, Wuxi Ninth People's Hospital Affiliated to Soochow University, Wuxi, Jiangsu, China., Zhu D; Department of Respiratory and Critical Care Medicine, Wuxi Ninth People's Hospital Affiliated to Soochow University, Wuxi, Jiangsu, China., Zhou Y; Department of Respiratory and Critical Care Medicine, Wuxi Ninth People's Hospital Affiliated to Soochow University, Wuxi, Jiangsu, China., Chen Z; Department of Respiratory and Critical Care Medicine, Wuxi Ninth People's Hospital Affiliated to Soochow University, Wuxi, Jiangsu, China., Huang X; Department of Respiratory and Critical Care Medicine, Wuxi Ninth People's Hospital Affiliated to Soochow University, Wuxi, Jiangsu, China.

المصدر: Allergologia et immunopathologia [Allergol Immunopathol (Madr)] 2024 Jul 01; Vol. 52 (4), pp. 60-67. Date of Electronic Publication: 2024 Jul 01 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Codon Publications Country of Publication: Singapore NLM ID: 0370073 Publication Model: eCollection Cited Medium: Internet ISSN: 1578-1267 (Electronic) Linking ISSN: 03010546 NLM ISO Abbreviation: Allergol Immunopathol (Madr) Subsets: MEDLINE

مواضيع طبية MeSH: Ferroptosis*/physiology , Pulmonary Disease, Chronic Obstructive*/metabolism , Pulmonary Disease, Chronic Obstructive*/genetics , Signal Transduction*/immunology , Amino Acid Transport System y+*/metabolism , Amino Acid Transport System y+*/genetics , Ubiquitin Thiolesterase*/metabolism , Ubiquitin Thiolesterase*/genetics, Animals ; Humans ; Mice ; Male ; Inflammation/metabolism ; Inflammation/immunology ; Disease Models, Animal ; Mice, Inbred C57BL ; Endosomal Sorting Complexes Required for Transport/metabolism ; Endosomal Sorting Complexes Required for Transport/genetics ; Cell Line ; Ubiquitin-Specific Proteases/metabolism ; Ubiquitin-Specific Proteases/genetics ; Endopeptidases

المؤلفون: Taurino G; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, Parma, Italy., Dander E; Tettamanti Center, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy., Chiu M; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, Parma, Italy., Pozzi G; Laboratory of Human Anatomy, Department of Medicine and Surgery, University of Parma, Parma, Italy., Maccari C; Laboratory of Industrial Toxicology, Department of Medicine and Surgery, University of Parma, Parma, Italy., Starace R; Tettamanti Center, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy., Silvestri D; Tettamanti Center, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy., Griffini E; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, Parma, Italy., Bianchi MG; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, Parma, Italy.; MRH-Microbiome Research Hub, Parco Area Delle Scienze 11/A, University of Parma, Parma, Italy., Carubbi C; Laboratory of Human Anatomy, Department of Medicine and Surgery, University of Parma, Parma, Italy., Andreoli R; Laboratory of Industrial Toxicology, Department of Medicine and Surgery, University of Parma, Parma, Italy.; CERT-Center of Excellence for Toxicological Research, University of Parma, Parma, Italy., Mirandola P; Laboratory of Human Anatomy, Department of Medicine and Surgery, University of Parma, Parma, Italy., Valsecchi MG; Biostatistics and Clinical Epidemiology, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Rizzari C; Department of Pediatrics, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy., D'Amico G; Tettamanti Center, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy., Bussolati O; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, Parma, Italy.; MRH-Microbiome Research Hub, Parco Area Delle Scienze 11/A, University of Parma, Parma, Italy.

المصدر: British journal of haematology [Br J Haematol] 2024 Jul; Vol. 205 (1), pp. 175-188. Date of Electronic Publication: 2024 May 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2141 (Electronic) Linking ISSN: 00071048 NLM ISO Abbreviation: Br J Haematol Subsets: MEDLINE

مواضيع طبية MeSH: Amino Acid Transport System ASC*/metabolism , Amino Acid Transport System ASC*/genetics , Asparagine*/metabolism , Minor Histocompatibility Antigens*/metabolism , Minor Histocompatibility Antigens*/genetics , Precursor B-Cell Lymphoblastic Leukemia-Lymphoma*/metabolism , Precursor B-Cell Lymphoblastic Leukemia-Lymphoma*/drug therapy , Precursor B-Cell Lymphoblastic Leukemia-Lymphoma*/pathology , Precursor B-Cell Lymphoblastic Leukemia-Lymphoma*/genetics , Cell Survival*/drug effects, Humans ; Amino Acid Transport System A/metabolism ; Amino Acid Transport System A/genetics ; Cell Line, Tumor ; Asparaginase/pharmacology ; Asparaginase/therapeutic use ; Cell Proliferation/drug effects ; Child

المؤلفون: Kuchur OA; National Research University ITMO, 197101 St. Petersburg, Russia., Pogodaeva SS; National Research University ITMO, 197101 St. Petersburg, Russia., Shcherbakova AV; National Research University ITMO, 197101 St. Petersburg, Russia., Tsymbal SA; National Research University ITMO, 197101 St. Petersburg, Russia.

المصدر: Bioscience reports [Biosci Rep] 2024 Jun 26; Vol. 44 (6).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 8102797 Publication Model: Print Cited Medium: Internet ISSN: 1573-4935 (Electronic) Linking ISSN: 01448463 NLM ISO Abbreviation: Biosci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Cyclin D1*/metabolism , Cyclin D1*/genetics , Tumor Suppressor Protein p53*/metabolism , Tumor Suppressor Protein p53*/genetics , Cell Survival*/drug effects , Copper Transport Proteins*/metabolism , Copper Transport Proteins*/genetics, Humans ; Hep G2 Cells ; A549 Cells ; Gene Expression Regulation, Neoplastic ; Molecular Chaperones/metabolism ; Molecular Chaperones/genetics ; Cell Proliferation ; Apoptosis ; Metallochaperones/metabolism ; Metallochaperones/genetics ; Cation Transport Proteins/metabolism ; Cation Transport Proteins/genetics