المؤلفون: Luo S; School of Food Engineering, Anhui Science and Technology University, Fengyang 233100, Anhui, China., Wei W; School of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, Jiangsu, China., Wu J; School of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, Jiangsu, China., Song W; School of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, Jiangsu, China., Hu G; School of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, Jiangsu, China., Liu L; School of Food Engineering, Anhui Science and Technology University, Fengyang 233100, Anhui, China.; Key Laboratory of Industrial Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, Jiangsu, China.

المصدر: Sheng wu gong cheng xue bao = Chinese journal of biotechnology [Sheng Wu Gong Cheng Xue Bao] 2024 Aug 25; Vol. 40 (8), pp. 2444-2456.

نوع المنشور: English Abstract; Journal Article

بيانات الدورية: Publisher: Ke xue chu ban she Country of Publication: China NLM ID: 9426463 Publication Model: Print Cited Medium: Internet ISSN: 1872-2075 (Electronic) Linking ISSN: 10003061 NLM ISO Abbreviation: Sheng Wu Gong Cheng Xue Bao Subsets: MEDLINE

مواضيع طبية MeSH: Indigo Carmine*/metabolism , Tryptophan*/metabolism , Tryptophan*/biosynthesis , Escherichia coli*/genetics , Escherichia coli*/metabolism, Protein Engineering ; Tryptophanase/genetics ; Tryptophanase/metabolism ; Tryptophan Synthase/metabolism ; Tryptophan Synthase/genetics ; Fermentation ; Oxygenases/genetics ; Oxygenases/metabolism

المؤلفون: Geeraerts Z; Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, United States., Ishigami I; Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, United States., Lewis-Ballester A; Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, United States., Pham KN; Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, United States., Kozlova A; Medicinal Chemistry Research Group (CMFA), Louvain Drug Research Institute (LDRI), Université Catholique de Louvain (UCLouvain), 73 avenue Mounier, Brussels B-1200, Belgium., Mathieu C; Medicinal Chemistry Research Group (CMFA), Louvain Drug Research Institute (LDRI), Université Catholique de Louvain (UCLouvain), 73 avenue Mounier, Brussels B-1200, Belgium., Frédérick R; Medicinal Chemistry Research Group (CMFA), Louvain Drug Research Institute (LDRI), Université Catholique de Louvain (UCLouvain), 73 avenue Mounier, Brussels B-1200, Belgium., Yeh SR; Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, United States.

المصدر: Journal of medicinal chemistry [J Med Chem] 2024 Aug 22; Vol. 67 (16), pp. 14543-14552. Date of Electronic Publication: 2024 Aug 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Tryptophan Oxygenase*/antagonists & inhibitors , Tryptophan Oxygenase*/metabolism , Tryptophan Oxygenase*/chemistry , Enzyme Inhibitors*/chemistry , Enzyme Inhibitors*/pharmacology , Enzyme Inhibitors*/metabolism , Indoleamine-Pyrrole 2,3,-Dioxygenase*/antagonists & inhibitors , Indoleamine-Pyrrole 2,3,-Dioxygenase*/metabolism , Indoleamine-Pyrrole 2,3,-Dioxygenase*/chemistry, Humans ; Structure-Activity Relationship ; Indoles/chemistry ; Indoles/pharmacology ; Indoles/metabolism ; Models, Molecular ; Tetrazoles/chemistry ; Tetrazoles/pharmacology ; Tetrazoles/metabolism ; Tryptophan/chemistry ; Tryptophan/metabolism ; Imidazoles/chemistry ; Imidazoles/pharmacology ; Imidazoles/metabolism ; Protein Binding

المؤلفون: Almhjell PJ; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, USA.; Department of Biochemistry, Stanford University, Stanford, CA, USA., Johnston KE; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.; Merck & Co., Inc, South San Francisco, CA, USA., Porter NJ; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, USA.; Codexis, Inc., Redwood City, CA, USA., Kennemur JL; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, USA., Bhethanabotla VC; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, USA., Ducharme J; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, USA.; Quebec Government Office, Los Angeles, CA, USA., Arnold FH; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, USA. frances@cheme.caltech.edu.; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA. frances@cheme.caltech.edu.

المصدر: Nature chemical biology [Nat Chem Biol] 2024 Aug; Vol. 20 (8), pp. 1086-1093. Date of Electronic Publication: 2024 May 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Tryptophan Synthase*/metabolism , Tryptophan Synthase*/chemistry , Tyrosine*/chemistry , Tyrosine*/metabolism, Catalytic Domain ; Models, Molecular ; Tyrosine Phenol-Lyase/metabolism ; Tyrosine Phenol-Lyase/chemistry ; Tyrosine Phenol-Lyase/genetics ; Protein Subunits/chemistry ; Protein Subunits/metabolism ; Biocatalysis ; Tryptophan/chemistry ; Tryptophan/metabolism

المؤلفون: Geeraerts Z; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States., Ishigami I; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States., Gao Y; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States., Yeh SR; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States. Electronic address: syun-ru.yeh@einsteinmed.edu.

المصدر: Journal of inorganic biochemistry [J Inorg Biochem] 2024 Dec; Vol. 261, pp. 112707. Date of Electronic Publication: 2024 Aug 30.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7905788 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3344 (Electronic) Linking ISSN: 01620134 NLM ISO Abbreviation: J Inorg Biochem Subsets: MEDLINE

مواضيع طبية MeSH: Tryptophan Oxygenase*/metabolism , Tryptophan Oxygenase*/chemistry , Heme*/chemistry , Heme*/metabolism , Indoleamine-Pyrrole 2,3,-Dioxygenase*/metabolism , Indoleamine-Pyrrole 2,3,-Dioxygenase*/chemistry, Humans ; Kynurenine/metabolism ; Kynurenine/chemistry ; Tryptophan/chemistry ; Tryptophan/metabolism ; Animals

المؤلفون: Wakasugi K; Komaba Organization for Educational Excellence, The University of Tokyo, 3-8-1 Komaba, Meguro-ku, Tokyo 153-8902, Japan.; Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, 3-8-1 Komaba, Meguro-ku, Tokyo 153-8902, Japan.; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan., Yokosawa T; Komaba Organization for Educational Excellence, The University of Tokyo, 3-8-1 Komaba, Meguro-ku, Tokyo 153-8902, Japan.

المصدر: Biochemical Society transactions [Biochem Soc Trans] 2024 Jun 26; Vol. 52 (3), pp. 1149-1158.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Portland Press On The Behalf Of The Biochemical Society Country of Publication: England NLM ID: 7506897 Publication Model: Print Cited Medium: Internet ISSN: 1470-8752 (Electronic) Linking ISSN: 03005127 NLM ISO Abbreviation: Biochem Soc Trans Subsets: MEDLINE

مواضيع طبية MeSH: Tryptophan*/metabolism , Indoleamine-Pyrrole 2,3,-Dioxygenase*/metabolism , Tryptophan-tRNA Ligase*/metabolism, Humans ; Biological Transport ; Tryptophan Oxygenase/metabolism ; Interferon-gamma/metabolism

المؤلفون: Shao J; Shaanxi Institute of Microbiology, Xiying Road 76, Xi'an, Shaanxi 710043, China.; Shaanxi Key Laboratory of Degradable Biomedical Materials, School of Chemical Engineering, Northwest University, Taibai North Road 229, Xi'an, Shaanxi 710069, China., Qu L; Shaanxi Key Laboratory of Degradable Biomedical Materials, School of Chemical Engineering, Northwest University, Taibai North Road 229, Xi'an, Shaanxi 710069, China., Liu Y; Shaanxi Institute of Microbiology, Xiying Road 76, Xi'an, Shaanxi 710043, China.; Shaanxi Key Laboratory of Degradable Biomedical Materials, School of Chemical Engineering, Northwest University, Taibai North Road 229, Xi'an, Shaanxi 710069, China., Zhang J; Shaanxi Institute of Microbiology, Xiying Road 76, Xi'an, Shaanxi 710043, China.; Shaanxi Key Laboratory of Degradable Biomedical Materials, School of Chemical Engineering, Northwest University, Taibai North Road 229, Xi'an, Shaanxi 710069, China., Liu Y; Shaanxi Key Laboratory of Degradable Biomedical Materials, School of Chemical Engineering, Northwest University, Taibai North Road 229, Xi'an, Shaanxi 710069, China., Deng J; Shaanxi Key Laboratory of Degradable Biomedical Materials, School of Chemical Engineering, Northwest University, Taibai North Road 229, Xi'an, Shaanxi 710069, China., Ma X; Shaanxi Key Laboratory of Degradable Biomedical Materials, School of Chemical Engineering, Northwest University, Taibai North Road 229, Xi'an, Shaanxi 710069, China., Fan D; Shaanxi Key Laboratory of Degradable Biomedical Materials, School of Chemical Engineering, Northwest University, Taibai North Road 229, Xi'an, Shaanxi 710069, China.

المصدر: Journal of agricultural and food chemistry [J Agric Food Chem] 2024 Apr 03; Vol. 72 (13), pp. 7100-7120. Date of Electronic Publication: 2024 Mar 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5118 (Electronic) Linking ISSN: 00218561 NLM ISO Abbreviation: J Agric Food Chem Subsets: MEDLINE

مواضيع طبية MeSH: Tryptophan* , Ginsenosides*/pharmacology, Animals ; Mice ; Humans ; Tryptophan Hydroxylase/genetics ; Brain-Gut Axis ; Depression/drug therapy ; Depression/genetics

المؤلفون: Wang Y; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, PR China., Liu W; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, PR China., Peng S; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, PR China., Chen Y; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, PR China., Chen F; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, PR China., Zhang A; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, PR China. Electronic address: zhangalei@njtech.edu.cn., Chen K; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, PR China. Electronic address: kqchen@njtech.edu.cn.

المصدر: International journal of biological macromolecules [Int J Biol Macromol] 2024 Apr; Vol. 264 (Pt 1), pp. 130609. Date of Electronic Publication: 2024 Mar 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

مواضيع طبية MeSH: 5-Hydroxytryptophan*/metabolism , Tryptophan Hydroxylase*/genetics , Tryptophan Hydroxylase*/metabolism, Animals ; Tryptophan/metabolism ; Serotonin/metabolism ; Protein Engineering

المؤلفون: Jiang L; State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China., Hao Y; State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China., Li Q; Laboratory of Animal Genetics, Breeding and Reproduction, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China., Dai Z; State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 18; Vol. 25 (12). Date of Electronic Publication: 2024 Jun 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Serotonin*/metabolism , Ileum*/metabolism , Ileum*/drug effects , Tryptophan*/metabolism , Signal Transduction*/drug effects , Cinnamates*/pharmacology , Cinnamates*/metabolism, Animals ; Mice ; Ion Transport/drug effects ; Male ; Tryptophan Hydroxylase/metabolism ; Tryptophan Hydroxylase/genetics ; Chlorogenic Acid/pharmacology ; Chlorogenic Acid/metabolism

المؤلفون: Liang J; Affiliated Psychological Hospital of Anhui Medical University, Hefei, China.; Department of Pharmacy, Hefei Fourth People's Hospital, Hefei, China.; Psychopharmacology Research Laboratory, Anhui Mental Health Center, Hefei, China.; Anhui Clinical Research Center for Mental Disorders, Hefei, China., Cheng ZY; Affiliated Psychological Hospital of Anhui Medical University, Hefei, China.; Department of Pharmacy, Hefei Fourth People's Hospital, Hefei, China.; Psychopharmacology Research Laboratory, Anhui Mental Health Center, Hefei, China.; Anhui Clinical Research Center for Mental Disorders, Hefei, China., Shan F; Affiliated Psychological Hospital of Anhui Medical University, Hefei, China.; Department of Pharmacy, Hefei Fourth People's Hospital, Hefei, China.; Psychopharmacology Research Laboratory, Anhui Mental Health Center, Hefei, China.; Anhui Clinical Research Center for Mental Disorders, Hefei, China., Cao Y; Affiliated Psychological Hospital of Anhui Medical University, Hefei, China.; Department of Pharmacy, Hefei Fourth People's Hospital, Hefei, China.; Psychopharmacology Research Laboratory, Anhui Mental Health Center, Hefei, China.; Anhui Clinical Research Center for Mental Disorders, Hefei, China., Xia QR; Affiliated Psychological Hospital of Anhui Medical University, Hefei, China. ahmcxqr@163.com.; Department of Pharmacy, Hefei Fourth People's Hospital, Hefei, China. ahmcxqr@163.com.; Psychopharmacology Research Laboratory, Anhui Mental Health Center, Hefei, China. ahmcxqr@163.com.; Anhui Clinical Research Center for Mental Disorders, Hefei, China. ahmcxqr@163.com.

المصدر: Psychopharmacology [Psychopharmacology (Berl)] 2024 May; Vol. 241 (5), pp. 1093-1099. Date of Electronic Publication: 2024 Jan 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7608025 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2072 (Electronic) Linking ISSN: 00333158 NLM ISO Abbreviation: Psychopharmacology (Berl) Subsets: MEDLINE

مواضيع طبية MeSH: Tryptophan* , Depressive Disorder, Major*/diagnosis, Humans ; Tryptophan Oxygenase ; Indoleamine-Pyrrole 2,3,-Dioxygenase ; Biomarkers

المؤلفون: Ding X; Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China., Jin Y; Department of Oncology, Shanghai Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China., Shi X; Department of Urology, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou, China., Wang Y; Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China; Department of Oncology, Shanghai Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China., Jin Z; Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China., Yin L; Department of Oncology, Shanghai Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China; Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Gao S; Department of Urology, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou, China; Department of Urology, Gonghe County Hospital of Traditional Chinese Medicine, Qinghai, China; Changzhou Medical Center, Nanjing Medical University, Changzhou, China. Electronic address: gaoshenglin12135@njmu.edu.cn., Lei Y; Department of Otology, Otolaryngology Hospital, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China. Electronic address: leiyibob@163.com., Yang J; Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China. Electronic address: yangjinjian@126.com.

المصدر: Biochemical pharmacology [Biochem Pharmacol] 2024 May; Vol. 223, pp. 116172. Date of Electronic Publication: 2024 Mar 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Tryptophan Oxygenase* , Urinary Bladder Neoplasms*/drug therapy , Urinary Bladder Neoplasms*/genetics, Humans ; Cisplatin/pharmacology ; Cisplatin/therapeutic use ; Cisplatin/metabolism ; Receptors, Aryl Hydrocarbon/genetics ; Receptors, Aryl Hydrocarbon/metabolism ; Tryptophan/metabolism ; Intracellular Signaling Peptides and Proteins/metabolism ; Osteonectin/genetics