المؤلفون: Kieft R; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA., Zhang Y; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA., Yan H; Department of Genetics, University of Georgia, Athens, GA 30602, USA., Schmitz RJ; Department of Genetics, University of Georgia, Athens, GA 30602, USA., Sabatini R; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA.

المصدر: Nucleic acids research [Nucleic Acids Res] 2024 Jul 08; Vol. 52 (12), pp. 6866-6885.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: RNA Polymerase II*/metabolism , RNA Polymerase II*/genetics , Protein Phosphatase 1*/genetics , Protein Phosphatase 1*/metabolism , Trypanosoma brucei brucei*/genetics , Trypanosoma brucei brucei*/enzymology , Transcription Termination, Genetic* , Protozoan Proteins*/genetics , Protozoan Proteins*/metabolism , Variant Surface Glycoproteins, Trypanosoma*/genetics , Variant Surface Glycoproteins, Trypanosoma*/metabolism , Alleles*, Phosphorylation ; Transcription, Genetic

المؤلفون: Sülzen H; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic.; Faculty of Science, Charles University, Prague, Czech Republic., Volkov AN; VIB-VUB Center for Structural Biology, Flemish Institute of Biotechnology (VIB), Brussels, Belgium.; Jean Jeener NMR Centre, Vrije Universiteit Brussel (VUB), Brussels, Belgium., Geens R; VIB-VUB Center for Structural Biology, Flemish Institute of Biotechnology (VIB), Brussels, Belgium.; Laboratory of Medical Biochemistry (LMB) and the Infla-Med Center of Excellence, Department of Pharmaceutical Sciences, Universiteit of Antwerp, Wilrijk, Belgium., Zahedifard F; Department of Parasitology, Faculty of Science, Charles University in Prague, Biocev, Vestec, Czech Republic., Stijlemans B; Brussels Center for Immunology (BCIM), Department of Bioengineering Sciences, Vrije Universiteit Brussel, Brussels, Belgium.; Myeloid Cell Immunology Laboratory, VIB Center for Inflammation Research, Brussels, Belgium., Zoltner M; Department of Parasitology, Faculty of Science, Charles University in Prague, Biocev, Vestec, Czech Republic., Magez S; Brussels Center for Immunology (BCIM), Department of Bioengineering Sciences, Vrije Universiteit Brussel, Brussels, Belgium.; Department of Biochemistry and Microbiology, Ghent University, Gent, Belgium.; Laboratory for Biomedical Research, Department of Molecular Biotechnology, Environment Technology and Food Technology, Ghent University Global Campus, Incheon, South Korea., Sterckx YG; Laboratory of Medical Biochemistry (LMB) and the Infla-Med Center of Excellence, Department of Pharmaceutical Sciences, Universiteit of Antwerp, Wilrijk, Belgium., Zoll S; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic.

المصدر: PLoS pathogens [PLoS Pathog] 2024 Apr 22; Vol. 20 (4), pp. e1012186. Date of Electronic Publication: 2024 Apr 22 (Print Publication: 2024).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

مواضيع طبية MeSH: Variant Surface Glycoproteins, Trypanosoma*/metabolism , Trypanosomiasis, African*/parasitology , Trypanosomiasis, African*/immunology, Protozoan Proteins/metabolism ; Humans ; Membrane Glycoproteins/metabolism ; Animals

المؤلفون: Lavergne G; Center for Integrative Genomics, Génopode Building, Faculty of Biology and Medicine, University of Lausanne, CH-1015, Lausanne, Switzerland., Roignant JY; Center for Integrative Genomics, Génopode Building, Faculty of Biology and Medicine, University of Lausanne, CH-1015, Lausanne, Switzerland; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg-University Mainz, Staudingerweg 5, 55128 Mainz, Germany. Electronic address: jean-yves.roignant@unil.ch.

المصدر: Molecular cell [Mol Cell] 2022 Jun 02; Vol. 82 (11), pp. 1979-1980.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Comment

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

مواضيع طبية MeSH: Trypanosoma brucei brucei*/genetics , Variant Surface Glycoproteins, Trypanosoma*/genetics, Animals ; Mammals ; Membrane Glycoproteins ; Poly A/genetics ; RNA, Messenger/genetics

المؤلفون: Viegas IJ; Instituto de Medicina Molecular-João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal., de Macedo JP; Instituto de Medicina Molecular-João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal., Serra L; Instituto de Medicina Molecular-João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal., De Niz M; Instituto de Medicina Molecular-João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal., Temporão A; Instituto de Medicina Molecular-João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal., Silva Pereira S; Instituto de Medicina Molecular-João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal., Mirza AH; Department of Pharmacology, Weill Medical College, Cornell University, New York, NY, USA., Bergstrom E; Department of Chemistry, University of York, York, UK.; Centre of Excellence in Mass Spectrometry, University of York, York, UK., Rodrigues JA; Instituto de Medicina Molecular-João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.; Clarify Analytical, Évora, Portugal., Aresta-Branco F; Instituto de Medicina Molecular-João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.; Division of Immune Diversity, German Cancer Research Center, Heidelberg, Germany.; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg, Germany., Jaffrey SR; Department of Pharmacology, Weill Medical College, Cornell University, New York, NY, USA., Figueiredo LM; Instituto de Medicina Molecular-João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal. lmf@medicina.ulisboa.pt.

المصدر: Nature [Nature] 2022 Apr; Vol. 604 (7905), pp. 362-370. Date of Electronic Publication: 2022 Mar 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: RNA Processing, Post-Transcriptional* , Trypanosoma brucei brucei*/genetics , Variant Surface Glycoproteins, Trypanosoma*/genetics, 3' Untranslated Regions/genetics ; Adenosine/analogs & derivatives ; Gene Expression Regulation ; RNA/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Transcription, Genetic

المؤلفون: Budzak J; Department of Life Sciences, Sir Alexander Fleming Building, Imperial College London, South Kensington, London, SW7 2AZ, UK., Jones R; Department of Life Sciences, Sir Alexander Fleming Building, Imperial College London, South Kensington, London, SW7 2AZ, UK., Tschudi C; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, 06536, USA., Kolev NG; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, 06536, USA., Rudenko G; Department of Life Sciences, Sir Alexander Fleming Building, Imperial College London, South Kensington, London, SW7 2AZ, UK. gloria.rudenko@imperial.ac.uk.

المصدر: Nature communications [Nat Commun] 2022 Jan 10; Vol. 13 (1), pp. 101. Date of Electronic Publication: 2022 Jan 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: RNA Splicing* , Transcription, Genetic*, Nuclear Bodies/*genetics , RNA, Messenger/*genetics , Trypanosoma brucei brucei/*genetics , Variant Surface Glycoproteins, Trypanosoma/*genetics, Cells, Cultured ; Gene Expression Regulation ; Membrane Glycoproteins/genetics ; Membrane Glycoproteins/metabolism ; Nuclear Bodies/metabolism ; Organisms, Genetically Modified ; Protozoan Proteins/genetics ; Protozoan Proteins/metabolism ; RNA Polymerase I/genetics ; RNA Polymerase I/metabolism ; RNA, Messenger/metabolism ; Trypanosoma brucei brucei/metabolism ; Variant Surface Glycoproteins, Trypanosoma/metabolism

المؤلفون: Hempelmann A; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg 69120, Germany., Hartleb L; Department of Cell and Developmental Biology, Theodor-Boveri-Institute, Biocenter, Julius-Maximilians-Universität of Würzburg, Würzburg 97074, Germany., van Straaten M; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg 69120, Germany., Hashemi H; Division of Immune Diversity, German Cancer Research Center, Heidelberg 69120, Germany., Zeelen JP; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg 69120, Germany., Bongers K; Department of Cell and Developmental Biology, Theodor-Boveri-Institute, Biocenter, Julius-Maximilians-Universität of Würzburg, Würzburg 97074, Germany., Papavasiliou FN; Division of Immune Diversity, German Cancer Research Center, Heidelberg 69120, Germany., Engstler M; Department of Cell and Developmental Biology, Theodor-Boveri-Institute, Biocenter, Julius-Maximilians-Universität of Würzburg, Würzburg 97074, Germany., Stebbins CE; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg 69120, Germany. Electronic address: e.stebbins@dkfz-heidelberg.de., Jones NG; Department of Cell and Developmental Biology, Theodor-Boveri-Institute, Biocenter, Julius-Maximilians-Universität of Würzburg, Würzburg 97074, Germany. Electronic address: nicola.jones@uni-wuerzburg.de.

المصدر: Cell reports [Cell Rep] 2021 Nov 02; Vol. 37 (5), pp. 109923.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Cell Membrane/*drug effects , Cell Movement/*drug effects , Single-Domain Antibodies/*pharmacology , Trypanocidal Agents/*pharmacology , Trypanosoma brucei brucei/*drug effects , Trypanosomiasis, African/*drug therapy , Variant Surface Glycoproteins, Trypanosoma/*immunology, Animals ; Antibody Specificity ; Binding Sites, Antibody ; Camelids, New World/immunology ; Cell Line ; Cell Membrane/immunology ; Cell Membrane/metabolism ; Cell Membrane/ultrastructure ; Endocytosis/drug effects ; Epitopes ; Exocytosis/drug effects ; Protein Binding ; Single-Domain Antibodies/immunology ; Single-Domain Antibodies/metabolism ; Trypanocidal Agents/immunology ; Trypanocidal Agents/metabolism ; Trypanosoma brucei brucei/immunology ; Trypanosoma brucei brucei/metabolism ; Trypanosoma brucei brucei/ultrastructure ; Trypanosomiasis, African/immunology ; Trypanosomiasis, African/metabolism ; Trypanosomiasis, African/parasitology ; Variant Surface Glycoproteins, Trypanosoma/metabolism

المؤلفون: Faria JRC; Wellcome Centre for Anti-Infectives Research, Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee, UK. joana.correiafaria@york.ac.uk.; Biology Department, University of York, York, UK. joana.correiafaria@york.ac.uk.; York Biomedical Research Institute, University of York, York, UK. joana.correiafaria@york.ac.uk., Tinti M; Wellcome Centre for Anti-Infectives Research, Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee, UK., Marques CA; Wellcome Centre for Anti-Infectives Research, Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee, UK.; Wellcome Centre for Integrative Parasitology, University of Glasgow, Glasgow, UK., Zoltner M; Wellcome Centre for Anti-Infectives Research, Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee, UK.; Faculty of Science, Charles University in Prague, Biocev, Vestec, Czech Republic., Yoshikawa H; Gene Regulation and Expression, School of Life Sciences, University of Dundee, Dundee, UK.; Division of Cell Signaling, Fujii Memorial Institute of Medical Sciences, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan., Field MC; Wellcome Centre for Anti-Infectives Research, Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee, UK.; Biology Centre, Czech Academy of Sciences, Institute of Parasitology, České Budějovice, Czech Republic., Horn D; Wellcome Centre for Anti-Infectives Research, Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee, UK. d.horn@dundee.ac.uk.

المصدر: Nature communications [Nat Commun] 2023 Dec 11; Vol. 14 (1), pp. 8200. Date of Electronic Publication: 2023 Dec 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Trypanosoma brucei brucei*/metabolism , Trypanosoma*/metabolism, Alleles ; Variant Surface Glycoproteins, Trypanosoma/metabolism ; Membrane Glycoproteins/genetics ; Telomere/metabolism

المؤلفون: Girasol MJ; College of Medical, Veterinary and Life Sciences, School of Infection and Immunity, Wellcome Centre for Integrative Parasitology, University of Glasgow, Glasgow G12 8TA, United Kingdom.; Faculty of the MD-PhD in Molecular Medicine Program, College of Medicine, University of the Philippines Manila, Manila 1000, Philippines., Krasilnikova M; College of Medical, Veterinary and Life Sciences, School of Infection and Immunity, Wellcome Centre for Integrative Parasitology, University of Glasgow, Glasgow G12 8TA, United Kingdom., Marques CA; College of Medical, Veterinary and Life Sciences, School of Infection and Immunity, Wellcome Centre for Integrative Parasitology, University of Glasgow, Glasgow G12 8TA, United Kingdom., Damasceno JD; College of Medical, Veterinary and Life Sciences, School of Infection and Immunity, Wellcome Centre for Integrative Parasitology, University of Glasgow, Glasgow G12 8TA, United Kingdom., Lapsley C; College of Medical, Veterinary and Life Sciences, School of Infection and Immunity, Wellcome Centre for Integrative Parasitology, University of Glasgow, Glasgow G12 8TA, United Kingdom., Lemgruber L; College of Medical, Veterinary and Life Sciences, School of Infection and Immunity, Wellcome Centre for Integrative Parasitology, University of Glasgow, Glasgow G12 8TA, United Kingdom., Burchmore R; College of Medical, Veterinary and Life Sciences, School of Infection and Immunity, Wellcome Centre for Integrative Parasitology, University of Glasgow, Glasgow G12 8TA, United Kingdom., Beraldi D; College of Medical, Veterinary and Life Sciences, School of Infection and Immunity, Wellcome Centre for Integrative Parasitology, University of Glasgow, Glasgow G12 8TA, United Kingdom., Carruthers R; College of Medical, Veterinary and Life Sciences, School of Cancer Sciences, University of Glasgow, Glasgow G12 0YN, United Kingdom., Briggs EM; College of Medical, Veterinary and Life Sciences, School of Infection and Immunity, Wellcome Centre for Integrative Parasitology, University of Glasgow, Glasgow G12 8TA, United Kingdom.; Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FL, United Kingdom., McCulloch R; College of Medical, Veterinary and Life Sciences, School of Infection and Immunity, Wellcome Centre for Integrative Parasitology, University of Glasgow, Glasgow G12 8TA, United Kingdom.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Nov 28; Vol. 120 (48), pp. e2309306120. Date of Electronic Publication: 2023 Nov 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Trypanosoma brucei brucei*, R-Loop Structures ; Antigenic Variation/genetics ; DNA Breaks ; DNA ; RNA ; Variant Surface Glycoproteins, Trypanosoma/genetics

المؤلفون: Thivolle A; Institut Pasteur, Université de Paris, Trypanosome Molecular Biology, Department of Parasites and Insect Vectors, Paris, France., Mehnert AK; Institut Pasteur, Université de Paris, Trypanosome Molecular Biology, Department of Parasites and Insect Vectors, Paris, France., Tihon E; Institut Pasteur, Université de Paris, Trypanosome Molecular Biology, Department of Parasites and Insect Vectors, Paris, France., McLaughlin E; Institut Pasteur, Université de Paris, Trypanosome Molecular Biology, Department of Parasites and Insect Vectors, Paris, France.; Université de Paris, Sorbonne Paris Cité, Paris, France., Dujeancourt-Henry A; Institut Pasteur, Université de Paris, Trypanosome Molecular Biology, Department of Parasites and Insect Vectors, Paris, France., Glover L; Institut Pasteur, Université de Paris, Trypanosome Molecular Biology, Department of Parasites and Insect Vectors, Paris, France.

المصدر: PLoS pathogens [PLoS Pathog] 2021 Nov 12; Vol. 17 (11), pp. e1010038. Date of Electronic Publication: 2021 Nov 12 (Print Publication: 2021).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

مواضيع طبية MeSH: Antigenic Variation* , DNA Breaks, Double-Stranded*, DNA, Protozoan/*genetics , Protozoan Proteins/*genetics , Trypanosoma/*immunology , Trypanosomiasis/*immunology , Variant Surface Glycoproteins, Trypanosoma/*genetics, Animals ; DNA Repair ; Gene Conversion ; Protozoan Proteins/immunology ; Repetitive Sequences, Nucleic Acid ; Trypanosoma/genetics ; Trypanosomiasis/genetics ; Trypanosomiasis/parasitology ; Variant Surface Glycoproteins, Trypanosoma/immunology

المؤلفون: Umaer K; Department of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo (SUNY), Buffalo, New York, USA.; Eurofins, Spring House, Pennsylvania, USA., Aresta-Branco F; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg, Germany.; Division of Immune Diversity, German Cancer Research Center, Heidelberg, Germany., Chandra M; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg, Germany.; Faculty of Biosciences, University of Heidelberg, Heidelberg, Germany., van Straaten M; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg, Germany., Zeelen J; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg, Germany., Lapouge K; Protein Expression and Purification Core Facility, EMBL Heidelberg, Heidelberg, Germany., Waxman B; Department of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo (SUNY), Buffalo, New York, USA., Stebbins CE; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg, Germany., Bangs JD; Department of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo (SUNY), Buffalo, New York, USA.

المصدر: Traffic (Copenhagen, Denmark) [Traffic] 2021 Aug; Vol. 22 (8), pp. 274-283. Date of Electronic Publication: 2021 Jun 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 100939340 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0854 (Electronic) Linking ISSN: 13989219 NLM ISO Abbreviation: Traffic Subsets: MEDLINE

مواضيع طبية MeSH: Trypanosoma brucei brucei* , Variant Surface Glycoproteins, Trypanosoma*/genetics, Cell Membrane ; Glycosylphosphatidylinositols ; Membrane Glycoproteins