المؤلفون: Zifkos K; Center for Thrombosis and Hemostasis (K.Z., M.L.B., D.P., K.K., W.R., C.R.), University Medical Center Mainz, Germany., Bochenek ML; Center for Thrombosis and Hemostasis (K.Z., M.L.B., D.P., K.K., W.R., C.R.), University Medical Center Mainz, Germany.; Department of Cardiology, Cardiology I (M.L.B., R.G., K.M., T.M., K.S.), University Medical Center Mainz, Germany., Gogiraju R; Department of Cardiology, Cardiology I (M.L.B., R.G., K.M., T.M., K.S.), University Medical Center Mainz, Germany., Robert S; Aix Marseille University, National Institute of Health and Medical Research (INSERM) 1263, National Research Institute for Agriculture, Food and Environment (INRAE), Cardiovascular and Nutrition Research Center (C2VN), France (S.R., L.P.-D., C.D.)., Pedrosa D; Center for Thrombosis and Hemostasis (K.Z., M.L.B., D.P., K.K., W.R., C.R.), University Medical Center Mainz, Germany., Kiouptsi K; Center for Thrombosis and Hemostasis (K.Z., M.L.B., D.P., K.K., W.R., C.R.), University Medical Center Mainz, Germany., Moiko K; Department of Cardiology, Cardiology I (M.L.B., R.G., K.M., T.M., K.S.), University Medical Center Mainz, Germany., Wagner M; Institute of Pathology, Saarland University Medical Center and Saarland University Faculty of Medicine, Homburg, Germany (M.W.)., Mahfoud F; Department of Internal Medicine III, Cardiology, Angiology and Internal Intensive Care Medicine, Saarland University Hospital and Saarland University, Homburg, Germany (F.M.)., Poncelet P; BioCytex, Marseille, France (P.P.)., Münzel T; Department of Cardiology, Cardiology I (M.L.B., R.G., K.M., T.M., K.S.), University Medical Center Mainz, Germany., Ruf W; Center for Thrombosis and Hemostasis (K.Z., M.L.B., D.P., K.K., W.R., C.R.), University Medical Center Mainz, Germany., Reinhardt C; Center for Thrombosis and Hemostasis (K.Z., M.L.B., D.P., K.K., W.R., C.R.), University Medical Center Mainz, Germany., Panicot-Dubois L; Aix Marseille University, National Institute of Health and Medical Research (INSERM) 1263, National Research Institute for Agriculture, Food and Environment (INRAE), Cardiovascular and Nutrition Research Center (C2VN), France (S.R., L.P.-D., C.D.)., Dubois C; Aix Marseille University, National Institute of Health and Medical Research (INSERM) 1263, National Research Institute for Agriculture, Food and Environment (INRAE), Cardiovascular and Nutrition Research Center (C2VN), France (S.R., L.P.-D., C.D.)., Schäfer K; Department of Cardiology, Cardiology I (M.L.B., R.G., K.M., T.M., K.S.), University Medical Center Mainz, Germany.

المصدر: Circulation research [Circ Res] 2024 May 10; Vol. 134 (10), pp. e93-e111. Date of Electronic Publication: 2024 Apr 02.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0047103 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4571 (Electronic) Linking ISSN: 00097330 NLM ISO Abbreviation: Circ Res Subsets: MEDLINE

مواضيع طبية MeSH: Protein Tyrosine Phosphatase, Non-Receptor Type 1*/genetics , Protein Tyrosine Phosphatase, Non-Receptor Type 1*/metabolism , Protein Tyrosine Phosphatase, Non-Receptor Type 1*/deficiency , Exocytosis* , von Willebrand Factor*/metabolism , von Willebrand Factor*/genetics , Venous Thrombosis*/metabolism , Venous Thrombosis*/genetics , Venous Thrombosis*/pathology , Mice, Knockout*, Animals ; Humans ; Mice ; Human Umbilical Vein Endothelial Cells/metabolism ; Inflammation/metabolism ; Inflammation/genetics ; Mice, Inbred C57BL ; Neutrophils/metabolism ; Endothelial Cells/metabolism ; Cells, Cultured ; Vena Cava, Inferior/metabolism ; Vena Cava, Inferior/pathology ; Male ; Neutrophil Infiltration ; NF-kappa B/metabolism

المؤلفون: Heger LA; Program in Cellular and Molecular Medicine, Boston Children's Hospital, 1 Blackfan Circle, Ninth Floor, Boston, MA, 02115, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, 02115, USA.; Departement of Cardiology and Angiology, University Hospital Freiburg Bad Krozingen, 79106, Freiburg, Germany., Schommer N; Program in Cellular and Molecular Medicine, Boston Children's Hospital, 1 Blackfan Circle, Ninth Floor, Boston, MA, 02115, USA.; Departement of Cardiology and Angiology, University Hospital Freiburg Bad Krozingen, 79106, Freiburg, Germany., Van Bruggen S; Program in Cellular and Molecular Medicine, Boston Children's Hospital, 1 Blackfan Circle, Ninth Floor, Boston, MA, 02115, USA.; Center of Molecular and Vascular Biology, Department of Cardiovascular Science, KU Leuven, 3000, Leuven, Belgium., Sheehy CE; Program in Cellular and Molecular Medicine, Boston Children's Hospital, 1 Blackfan Circle, Ninth Floor, Boston, MA, 02115, USA., Chan W; Program in Cellular and Molecular Medicine, Boston Children's Hospital, 1 Blackfan Circle, Ninth Floor, Boston, MA, 02115, USA., Wagner DD; Program in Cellular and Molecular Medicine, Boston Children's Hospital, 1 Blackfan Circle, Ninth Floor, Boston, MA, 02115, USA. denisa.wagner@childrens.harvard.edu.; Department of Pediatrics, Harvard Medical School, Boston, MA, 02115, USA. denisa.wagner@childrens.harvard.edu.; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, 02115, USA. denisa.wagner@childrens.harvard.edu.

المصدر: Scientific reports [Sci Rep] 2024 Jun 24; Vol. 14 (1), pp. 14524. Date of Electronic Publication: 2024 Jun 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism , NLR Family, Pyrin Domain-Containing 3 Protein*/genetics , Neutrophils*/metabolism , Interleukin-1beta*/metabolism , Myocardial Infarction*/metabolism , Myocardial Infarction*/pathology , Extracellular Traps*/metabolism , Myocardium*/metabolism , Myocardium*/pathology , Mice, Knockout* , von Willebrand Factor*/metabolism , von Willebrand Factor*/genetics, Animals ; Mice ; Mice, Inbred C57BL ; Male ; Inflammasomes/metabolism ; Disease Models, Animal

المؤلفون: Liu YS; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China., Chen WL; Scientific Research Center, the Medical Interdisciplinary Science Research Center of Western Guangdong, College of Women and Children, the Second Affiliated Hospital of Guangdong Medical University, Zhanjiang 524023, China., Zeng YW; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China., Li ZH; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China., Zheng HL; Division of Biosciences, University College London, London WC1E 6BT, UK., Pan N; Department of Pharmacy, The Second Clinical College, Guangzhou Medical University, Guangzhou 510261, China., Zhao LY; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China., Wang S; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China., Chen SH; School of Marine Sciences, Sun Yat-sen University, Guangzhou 510006, China.; Southern Marine Sciences and Engineering Guangdong Laboratory (Zhuhai), Zhuhai 519000, China., Jiang MH; School of Marine Sciences, Sun Yat-sen University, Guangzhou 510006, China.; Southern Marine Sciences and Engineering Guangdong Laboratory (Zhuhai), Zhuhai 519000, China., Jin CC; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China., Mi YC; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China., Cai ZH; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China., Fang XZ; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China., Liu YJ; Guangdong Provincial Clinical Research Center of Critical Care Medicine, Guangzhou 510080, China.; Department of Critical Care Medicine, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China., Liu L; School of Marine Sciences, Sun Yat-sen University, Guangzhou 510006, China.; Southern Marine Sciences and Engineering Guangdong Laboratory (Zhuhai), Zhuhai 519000, China., Wang GL; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.

المصدر: Marine drugs [Mar Drugs] 2024 Jun 16; Vol. 22 (6). Date of Electronic Publication: 2024 Jun 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101213729 Publication Model: Electronic Cited Medium: Internet ISSN: 1660-3397 (Electronic) Linking ISSN: 16603397 NLM ISO Abbreviation: Mar Drugs Subsets: MEDLINE

مواضيع طبية MeSH: Sepsis*/drug therapy , von Willebrand Factor*/metabolism , Human Umbilical Vein Endothelial Cells*/drug effects , Blood Platelets*/drug effects , Blood Platelets*/metabolism, Animals ; Humans ; Mice ; Male ; Disease Models, Animal ; Mice, Inbred C57BL ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/metabolism ; Integrin alphaVbeta3/metabolism ; Integrin alphaVbeta3/antagonists & inhibitors ; Capillary Permeability/drug effects

المؤلفون: Dachy G; Service d'Hématologie, Institut Roi Albert II, Cliniques Universitaires Saint-Luc, Brussels, Belgium. guillaume.dachy@uclouvain.saintluc.be., Vankeerbergen M; Service d'Hématologie, Institut Roi Albert II, Cliniques Universitaires Saint-Luc, Brussels, Belgium., Vanlangendonck N; Service d'Hématologie, Institut Roi Albert II, Cliniques Universitaires Saint-Luc, Brussels, Belgium., Straetmans N; Service d'Hématologie, Institut Roi Albert II, Cliniques Universitaires Saint-Luc, Brussels, Belgium., Lambert C; Service d'Hématologie, Institut Roi Albert II, Cliniques Universitaires Saint-Luc, Brussels, Belgium., Hermans C; Service d'Hématologie, Institut Roi Albert II, Cliniques Universitaires Saint-Luc, Brussels, Belgium., Poiré X; Service d'Hématologie, Institut Roi Albert II, Cliniques Universitaires Saint-Luc, Brussels, Belgium.

المصدر: Bone marrow transplantation [Bone Marrow Transplant] 2024 Jun; Vol. 59 (6), pp. 890-892. Date of Electronic Publication: 2024 Mar 08.

نوع المنشور: Letter

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8702459 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5365 (Electronic) Linking ISSN: 02683369 NLM ISO Abbreviation: Bone Marrow Transplant Subsets: MEDLINE

مواضيع طبية MeSH: Hematopoietic Stem Cell Transplantation*/adverse effects , von Willebrand Factor*/metabolism , von Willebrand Factor*/analysis , Biomarkers*/blood, Humans ; Male ; Female ; Middle Aged ; Adult ; Transplantation, Homologous/adverse effects ; Allografts ; Aged

المؤلفون: Rahmati N; Department of Systems Design Engineering, University of Waterloo, 200 University Avenue West, Waterloo, ON, N2L 3G1, Canada.; Centre for Bioengineering and Biotechnology, University of Waterloo, Waterloo, ON, Canada., Keshavarz Motamed P; Department of Systems Design Engineering, University of Waterloo, 200 University Avenue West, Waterloo, ON, N2L 3G1, Canada.; Centre for Bioengineering and Biotechnology, University of Waterloo, Waterloo, ON, Canada., Maftoon N; Department of Systems Design Engineering, University of Waterloo, 200 University Avenue West, Waterloo, ON, N2L 3G1, Canada. nmaftoon@uwaterloo.ca.; Centre for Bioengineering and Biotechnology, University of Waterloo, Waterloo, ON, Canada. nmaftoon@uwaterloo.ca.

المصدر: Biomechanics and modeling in mechanobiology [Biomech Model Mechanobiol] 2024 Jun; Vol. 23 (3), pp. 737-756. Date of Electronic Publication: 2024 Jan 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: Germany NLM ID: 101135325 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1617-7940 (Electronic) Linking ISSN: 16177940 NLM ISO Abbreviation: Biomech Model Mechanobiol Subsets: MEDLINE

مواضيع طبية MeSH: Blood Coagulation Disorders*/blood , Blood Coagulation Disorders*/metabolism , von Willebrand Factor*/metabolism, Humans ; Blood Platelets/metabolism ; Computer Simulation ; Models, Biological ; Numerical Analysis, Computer-Assisted ; Platelet Adhesiveness ; Protein Multimerization ; Stress, Mechanical ; Thrombosis/metabolism

المؤلفون: Dominik N; Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.; Vienna Hepatic Hemodynamic Lab, Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria., Scheiner B; Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.; Vienna Hepatic Hemodynamic Lab, Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.; Department of Surgery and Cancer, Imperial College London, London, UK., Zanetto A; Gastroenterology and Multivisceral Transplant Unit, Department of Surgery, Oncology and Gastroenterology, Padova University Hospital, Padova, Italy., Balcar L; Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.; Vienna Hepatic Hemodynamic Lab, Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria., Semmler G; Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.; Vienna Hepatic Hemodynamic Lab, Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria., Campello E; General Internal Medicine Unit, Thrombotic and Haemorrhagic Disease Unit and Haemophilia Center, Department of Medicine (DIMED), Padova University Hospital, Padova, Italy., Schwarz M; Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.; Vienna Hepatic Hemodynamic Lab, Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria., Paternostro R; Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.; Vienna Hepatic Hemodynamic Lab, Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria., Simbrunner B; Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.; Vienna Hepatic Hemodynamic Lab, Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.; Christian Doppler Laboratory for Portal Hypertension and Liver Fibrosis, Medical University of Vienna, Vienna, Austria., Hofer BS; Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.; Vienna Hepatic Hemodynamic Lab, Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria., Stättermayer AF; Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.; Vienna Hepatic Hemodynamic Lab, Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria., Pinter M; Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria., Trauner M; Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria., Quehenberger P; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria., Simioni P; General Internal Medicine Unit, Thrombotic and Haemorrhagic Disease Unit and Haemophilia Center, Department of Medicine (DIMED), Padova University Hospital, Padova, Italy., Reiberger T; Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.; Vienna Hepatic Hemodynamic Lab, Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.; Department of Surgery and Cancer, Imperial College London, London, UK., Mandorfer M; Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.; Vienna Hepatic Hemodynamic Lab, Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.

المصدر: Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2024 Jun; Vol. 59 (11), pp. 1376-1386. Date of Electronic Publication: 2024 Mar 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 8707234 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2036 (Electronic) Linking ISSN: 02692813 NLM ISO Abbreviation: Aliment Pharmacol Ther Subsets: MEDLINE

مواضيع طبية MeSH: von Willebrand Factor*/metabolism , von Willebrand Factor*/analysis , Biomarkers*/blood , C-Reactive Protein*/analysis, Humans ; Male ; Female ; Middle Aged ; Retrospective Studies ; Prognosis ; Aged ; Liver Diseases/blood ; Liver Diseases/mortality ; Chronic Disease ; Adult ; Severity of Illness Index ; Predictive Value of Tests

المؤلفون: Schellenberg C; Université de Lorraine, INSERM, DCAC, Nancy, France., Lagrange J; Université de Lorraine, INSERM, DCAC, Nancy, France.; CHRU Nancy, IHU INFINY, Vandœuvre-lès-Nancy, France., Ahmed MU; Université de Lorraine, INSERM, DCAC, Nancy, France., Arnone D; Université de Lorraine, INSERM, NGERE, IHU INFINY, Nancy, France., Campoli P; CHRU Nancy, Anatomie et Cytologie Pathologiques, Nancy, France., Louis H; Université de Lorraine, INSERM, DCAC, Nancy, France., Touly N; CHRU Nancy, IHU INFINY, Vandœuvre-lès-Nancy, France., Caron B; Université de Lorraine, INSERM, NGERE, IHU INFINY, Nancy, France.; Department of Gastroenterology, CHRU Nancy, Vandœuvre-lès-Nancy, France., Plénat F; Université de Lorraine, Nancy, France., Perrin J; Université de Lorraine, INSERM, DCAC, Nancy, France.; CHRU Nancy, Service d'Hématologie Biologique, Nancy, France., Lenting PJ; HITh, UMR_S1176, INSERM, Université Paris-Saclay, Le Kremlin-Bicêtre, France., Regnault V; Université de Lorraine, INSERM, DCAC, Nancy, France., Lacolley P; Université de Lorraine, INSERM, DCAC, Nancy, France., Denis CV; HITh, UMR_S1176, INSERM, Université Paris-Saclay, Le Kremlin-Bicêtre, France., Peyrin-Biroulet L; Université de Lorraine, INSERM, NGERE, IHU INFINY, Nancy, France.; Department of Gastroenterology, CHRU Nancy, Vandœuvre-lès-Nancy, France.; Groupe Hospitalier privé Ambroise Paré - Hartmann, Paris IBD Center, Neuilly sur Seine, France.

المصدر: Journal of Crohn's & colitis [J Crohns Colitis] 2024 May 31; Vol. 18 (5), pp. 751-761.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 101318676 Publication Model: Print Cited Medium: Internet ISSN: 1876-4479 (Electronic) Linking ISSN: 18739946 NLM ISO Abbreviation: J Crohns Colitis Subsets: MEDLINE

مواضيع طبية MeSH: von Willebrand Factor*/metabolism , Blood Platelets*/metabolism , Inflammatory Bowel Diseases*/blood , Inflammatory Bowel Diseases*/complications , Disease Models, Animal* , Phenotype*, Animals ; Humans ; Mice ; Male ; Female ; Adult ; Middle Aged ; Colitis/blood ; Colitis/complications ; Colitis/metabolism ; Thrombin/metabolism ; Mice, Inbred C57BL ; Thrombosis/etiology ; Thrombosis/blood ; Blood Coagulation/physiology ; Case-Control Studies

المؤلفون: Arce NA; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA., Markham-Lee Z; Biodiscovery Institute, School of Pharmacy, University of Nottingham, Nottingham, United Kingdom., Liang Q; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA.; Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China., Najmudin S; Biodiscovery Institute, School of Pharmacy, University of Nottingham, Nottingham, United Kingdom., Legan ER; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA., Dean G; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA., Su AJ; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA., Wilson MS; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA., Sidonio RF; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA., Lollar P; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA., Emsley J; Biodiscovery Institute, School of Pharmacy, University of Nottingham, Nottingham, United Kingdom., Li R; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA.

المصدر: Blood [Blood] 2024 May 09; Vol. 143 (19), pp. 1992-2004.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: von Willebrand Factor*/metabolism , von Willebrand Factor*/chemistry , Single-Domain Antibodies*/pharmacology , Single-Domain Antibodies*/chemistry , Single-Domain Antibodies*/metabolism, Humans ; Platelet Aggregation/drug effects ; Protein Conformation ; Protein Domains ; Protein Binding ; Platelet Adhesiveness/drug effects ; Crystallography, X-Ray ; Animals ; Blood Platelets/metabolism

المؤلفون: de Vries PS; Department of Epidemiology, Human Genetics, and Environmental Sciences, Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX., Reventun P; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD., Brown MR; Department of Epidemiology, Human Genetics, and Environmental Sciences, Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX., Heath AS; Department of Epidemiology, Human Genetics, and Environmental Sciences, Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX., Huffman JE; Massachusetts Veterans Epidemiology Research and Information Center, VA Boston Healthcare System, Boston, MA., Le NQ; Unit of Genomics of Complex Disease, Institut de Recerca Sant Pau, Barcelona, Spain., Bebo A; Department of Epidemiology, Human Genetics, and Environmental Sciences, Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA., Temprano-Sagrera G; Unit of Genomics of Complex Disease, Institut de Recerca Sant Pau, Barcelona, Spain., Raffield LM; Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Ozel AB; Department of Human Genetics, University of Michigan, Ann Arbor, MI., Thibord F; Division of Intramural Research, Population Sciences Branch, National Heart, Lung, and Blood Institute, Framingham Heart Study, Framingham, MA., Jain D; Department of Biostatistics, Genetic Analysis Center, School of Public Health, University of Washington, Seattle, WA., Lewis JP; Department of Medicine, University of Maryland, Baltimore, MD., Rodriguez BAT; Division of Intramural Research, Population Sciences Branch, National Heart, Lung, and Blood Institute, Framingham Heart Study, Framingham, MA., Pankratz N; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA., Taylor KD; Department of Pediatrics, Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA., Polasek O; Faculty of Medicine, University of Split, Split, Croatia., Chen MH; Division of Intramural Research, Population Sciences Branch, National Heart, Lung, and Blood Institute, Framingham Heart Study, Framingham, MA., Yanek LR; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD., Carrasquilla GD; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Marioni RE; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland., Kleber ME; SYNLAB MVZ Humangenetik Mannheim, Mannheim, Germany.; Fifth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Trégouët DA; INSERM UMR 1219, Bordeaux Population Health Research Center, Bordeaux, France., Yao J; Department of Pediatrics, Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Joshi PK; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, Scotland., Trompet S; Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands., Martinez-Perez A; Unit of Genomics of Complex Disease, Institut de Recerca Sant Pau, Barcelona, Spain., Ghanbari M; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Howard TE; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX., Reiner AP; Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA., Arvanitis M; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD., Ryan KA; Department of Medicine, University of Maryland, Baltimore, MD., Bartz TM; Departments of Biostatistics and Medicine, Cardiovascular Health Research Unit, University of Washington, Seattle, WA., Rudan I; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, Scotland., Faraday N; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD., Linneberg A; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Ekunwe L; Department of Medicine, University of Mississippi Medical Center, Jackson, MS., Davies G; Department of Psychology, Lothian Birth Cohorts, University of Edinburgh, Edinburgh, Scotland., Delgado GE; Fifth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Suchon P; C2VN, INSERM, INRAE, Aix Marseille University, Marseille, France.; Laboratory of Haematology, La Timone Hospital, Marseille, France., Guo X; Department of Pediatrics, Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA., Rosendaal FR; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Klaric L; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland., Noordam R; Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands., van Rooij F; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Curran JE; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX., Wheeler MM; Department of Genome Sciences, University of Washington, Seattle, WA., Osburn WO; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD., O'Connell JR; Department of Medicine, University of Maryland, Baltimore, MD., Boerwinkle E; Department of Epidemiology, Human Genetics, and Environmental Sciences, Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX., Beswick A; Translational Health Sciences, University of Bristol, Bristol, United Kingdom., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA.; Departments of Epidemiology and Health Systems and Population Health, Seattle, WA., Kolcic I; Faculty of Medicine, University of Split, Split, Croatia., Souto JC; Unit of Genomics of Complex Disease, Institut de Recerca Sant Pau, Barcelona, Spain.; Unit of Thrombosis and Hemostasis, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Becker LC; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark., Doyle MF; Department of Pathology and Laboratory Medicine, Larner College of Medicine, University of Vermont, Colchester, VT., Harris SE; Department of Psychology, Lothian Birth Cohorts, University of Edinburgh, Edinburgh, Scotland., Moissl AP; Institute of Nutritional Sciences, Friedrich-Schiller-University Jena, Jena, Germany.; Competence Cluster for Nutrition and Cardiovascular Health Halle-Jena-Leipzig, Jena, Germany., Deleuze JF; Centre National de Recherche en Génomique Humaine, Université Paris-Saclay, CEA, Evry, France.; Centre d'Etude du Polymorphisme Humain, Fondation Jean Dausset, Paris, France., Rich SS; Department of Public Health Sciences, Center for Public Health Genomics, University of Virginia, Charlottesville, VA., van Hylckama Vlieg A; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Campbell H; 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المصدر: Blood [Blood] 2024 May 02; Vol. 143 (18), pp. 1845-1855.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: von Willebrand Factor*/genetics , von Willebrand Factor*/metabolism , Factor VIII*/genetics , Factor VIII*/metabolism , Kininogens* , Receptors, Cell Surface* , Cell Adhesion Molecules* , Lectins, C-Type*, Humans ; Polymorphism, Single Nucleotide ; Human Umbilical Vein Endothelial Cells/metabolism ; Mendelian Randomization Analysis ; Genome-Wide Association Study ; Thrombosis/genetics ; Thrombosis/blood ; Genetic Association Studies ; Male ; Endothelial Cells/metabolism ; Female

المؤلفون: Ozawa K; Sydney Medical School Nepean, Faculty of Medicine and Health, Department of Cardiology, The University of Sydney, Nepean Hospital, Sydney, NSW, Australia., Packwood W; Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR, USA., Muller MA; Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR, USA., Qi Y; Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR, USA., Xie A; Cardiovascular Division and Robert M. Berne Cardiovascular Research Center, University of Virginia, Box 801394, 415 Lane Rd, Charlottesville, VA, 22908, USA., Varlamov O; Oregon National Primate Research Center, Portland, OR, USA., McCarty OJ; Department of Biomedical Engineering, Oregon Health & Science University, Portland, USA., Chung D; BloodWorks Research Institute, University of Washington, Seattle, WA, USA., López JA; BloodWorks Research Institute, University of Washington, Seattle, WA, USA., Lindner JR; Cardiovascular Division and Robert M. Berne Cardiovascular Research Center, University of Virginia, Box 801394, 415 Lane Rd, Charlottesville, VA, 22908, USA. jlindner@virginia.edu.

المصدر: Journal of translational medicine [J Transl Med] 2024 May 01; Vol. 22 (1), pp. 412. Date of Electronic Publication: 2024 May 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: von Willebrand Factor*/metabolism , Myocardial Infarction*/pathology , Myocardial Infarction*/complications , ADAMTS13 Protein*/metabolism, Animals ; Vascular Cell Adhesion Molecule-1/metabolism ; Mice ; Plaque, Atherosclerotic/pathology ; P-Selectin/metabolism ; Endothelial Cells/metabolism ; Endothelial Cells/drug effects ; Male ; Molecular Imaging ; Aorta/pathology ; Aorta/drug effects ; Acetylcysteine/pharmacology ; Acetylcysteine/therapeutic use ; Mice, Inbred C57BL