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1دورية أكاديمية
المؤلفون: DeNies Maxwell S., Liu Allen P., Schnell Santiago
المصدر: Biomolecular Concepts, Vol 15, Iss 1, Pp 895-8 (2024)
مصطلحات موضوعية: rigor, reproducibility, undergraduate and graduate research education, experimental design, biometrology, quantitative biology, western blots, protein abundance, post-translational modification, cell signaling, Biology (General), QH301-705.5
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1868-503X
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2دورية أكاديمية
المؤلفون: Mandelli, S., Cozzolino, D., Cannas, E.D., Cardenuto, J.P., Moreira, D., Bestagini, P., Scheirer, W.J., Rocha, A., Verdoliva, L., Tubaro, S., Delp, E.J.
المصدر: IEEE Access Access, IEEE. 10:59919-59932 2022
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3دورية أكاديمية
المؤلفون: Heidy K. Latchman, author1, Stefan G. Wette, author1, Dion J. Ellul, author1, Robyn M. Murphy, author1, Noni T. Frankenberg, author1
المصدر: Journal of Visualized Experiments. (199)
الإتاحة: http://www.jove.com/video/65750
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4دورية أكاديمية
المؤلفون: Sara Mandelli, Davide Cozzolino, Edoardo D. Cannas, Joao P. Cardenuto, Daniel Moreira, Paolo Bestagini, Walter J. Scheirer, Anderson Rocha, Luisa Verdoliva, Stefano Tubaro, Edward J. Delp
المصدر: IEEE Access, Vol 10, Pp 59919-59932 (2022)
مصطلحات موضوعية: Western blots, GANs, denoising diffusion probabilistic models, synthetically generated images, image forensics, Electrical engineering. Electronics. Nuclear engineering, TK1-9971
وصف الملف: electronic resource
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5دورية أكاديمية
المؤلفون: Duncombe, Todd A, Kang, Chi-Chih, Maity, Santanu, Ward, Toby M, Pegram, Mark D, Murthy, Niren, Herr, Amy E
المصدر: Advanced Materials. 28(2)
مصطلحات موضوعية: Engineering, Biomedical Engineering, Cancer, Bioengineering, Blotting, Western, Breast Neoplasms, Cell Line, Tumor, Electrophoresis, Polyacrylamide Gel, Extracellular Signal-Regulated MAP Kinases, Green Fluorescent Proteins, Humans, Hydrogels, Light, Nucleocytoplasmic Transport Proteins, Porosity, Receptor, ErbB-2, Single-Cell Analysis, TOR Serine-Threonine Kinases, Receptor, erbB-2, cancer therapies, gradient gels, grayscale masks, hydrogel pore expansion, western blots, Physical Sciences, Chemical Sciences, Nanoscience & Nanotechnology, Chemical sciences, Physical sciences
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/99c7h5dg
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6دورية أكاديمية
المؤلفون: Ana H. Sales, Marina Kolbanovskiy, Nicholas E. Geacintov, Kun-Ming Chen, Yuan-Wan Sun, Karam El-Bayoumy
المصدر: Antioxidants, Vol 11, Iss 11, p 2110 (2022)
مصطلحات موضوعية: black raspberry extracts, oxidative DNA damage and repair, bulky benzo[a]pyrene DNA adducts, expression of nucleotide excision repair proteins, western blots, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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7دورية أكاديمية
المؤلفون: Faouzi Zarrouki, Sébastien Goutal, Ophélie Vacca, Luis Garcia, Nicolas Tournier, Aurélie Goyenvalle, Cyrille Vaillend
المصدر: International Journal of Molecular Sciences, Vol 23, Iss 20, p 12617 (2022)
مصطلحات موضوعية: Duchenne muscular dystrophy, GABAergic synapses, PET brain imaging, immunofluorescence, western blots, GABAA-receptor clustering, Biology (General), QH301-705.5, Chemistry, QD1-999
وصف الملف: electronic resource
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8دورية أكاديمية
المؤلفون: M. M. Guzyk, T. M. Tykhonenko, K. O. Dyakun, L. V. Yanitska, I. B. Pryvrotska, T. M. Kuchmerovska
المصدر: The Ukrainian Biochemical Journal, Vol 91, Iss 1, Pp 21-29 (2019)
مصطلحات موضوعية: one of the serious complications of diabetes mellitus, is complex. In this study, we examined whether expression levels of SIRT1 and SIRT2 were the key for the development of brain dysfunctions and whether PARP-1 inhibitors could affect the expression of these proteins for prevention the development of DE in rats with type 1 diabetes. After 10 weeks of the streptozotocin-induced diabetes mellitus (70 mg/kg), Wistar male rats were treated by i.p. injection with PARP-1 inhibitors, 1.5-isoquinolinediol (ISO) or nicotinamide (NAm) (3 or 100 mg/kg/daily i.p., respectively) for 2 weeks. The rats with blood glucose levels over 19.7 ± 2.1 mmol/l were taken into experiments. Western blots were performed to evaluate effects of PAPR-1 inhibitors on the levels of sirtuins, SIRT1 and SIRT2 expression. Diabetes induced significant reduction of SIRT1 expression and SIRT2 overexpression in brain nuclear extracts of diabetic rats compared to non-diabetic control. In brain, NAm attenuated SIRT2 overexpression in nuclear extracts of diabetic rats and slightly elevated SIRT1 expression, while ISO didn’t affect expression of both sirtuins in diabetic rats. Furthermore, it was observed that in brain of diabetic rats, the ratio of free NAD/NADH couples decreased 3.1-fold compared to non-diabetic control. The administration of ISO increased only slightly the ratio of free NAD/NADH couples in the brain of diabetic rats while NAm increased this parameter 1.7-fold compared to diabetic rats. Therefore, 1.5-isoquinolinediol (ISO), diabetes mellitus, expression of sirtuins, nicotinamide (NAm), PARP-1 inhibitors, SIRT1, SIRT2, Biochemistry, QD415-436, Medicine, Biology (General), QH301-705.5
وصف الملف: electronic resource
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9دورية أكاديمية
المؤلفون: Miles W. DeAngelis, author1, Ruth I. Johnson, author1
المصدر: Journal of Visualized Experiments. (145)
الإتاحة: http://www.jove.com/video/59299
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10دورية أكاديمية
المؤلفون: Schüssler, Christina, Freitag, Helmut, Koteyeva, Nuria, Schmidt, Denise, Edwards, Gerald, Voznesenskaya, Elena, Kadereit, Gudrun
المصدر: Journal of Experimental Botany, 2017 Jan 01. 68(2), 207-223.
URL الوصول: https://www.jstor.org/stable/26391471