دورية أكاديمية
The characteristics of large bowel cancer in the low-risk black population of the Witwatersrand.
| العنوان: | The characteristics of large bowel cancer in the low-risk black population of the Witwatersrand. |
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| المؤلفون: | Boytchev H; Department of Surgery, University of the Witwatersrand, Johannesburg, Republic of South Africa., Marcovic S, Oettle GJ |
| المصدر: | Journal of the Royal College of Surgeons of Edinburgh [J R Coll Surg Edinb] 1999 Dec; Vol. 44 (6), pp. 366-70. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Playfair Trust on behalf of the Royal College of Surgeons of Edinburgh Country of Publication: Scotland NLM ID: 7503110 Publication Model: Print Cited Medium: Print ISSN: 0035-8835 (Print) Linking ISSN: 00358835 NLM ISO Abbreviation: J R Coll Surg Edinb Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 1999-2002: Edinburgh : Playfair Trust on behalf of the Royal College of Surgeons of Edinburgh Original Publication: Edinburgh. |
| مواضيع طبية MeSH: | Black People*, Colorectal Neoplasms/*epidemiology, Adolescent ; Adult ; Age of Onset ; Aged ; Aged, 80 and over ; Colorectal Neoplasms/pathology ; Diet ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Staging ; Risk Factors ; Sex Factors ; South Africa/epidemiology ; Urban Population |
| مستخلص: | Sporadic colorectal cancer may follow a different pathogenic pathway in low-risk populations. The black population of the Witwatersrand has been urbanized for a long time, and has a westernized lifestyle, but colorectal cancer is still infrequent. This study aimed to define the characteristics of the disease in this group. All histologically proven large bowel cancers arising in blacks resident in the Witwatersrand in 1991 and 1996 were extracted from the registry records. Mean age was 54.3 years (range 16-90 years); 6% occurred before 30 years and 22% before 40 years. Male:female ratio was 1.32:1. Over three-quarters of the tumours arose in the rectum and sigmoid; there was no evidence of a right-sided preponderance. More than half the cases were advanced at presentation, and nearly one third were mucinous or signet ring on pathological assessment. Associated adenomata were rare (5.2%), suggesting a different pathogenic pathway from the classical adenoma-carcinoma sequence. |
| تواريخ الأحداث: | Date Created: 19991229 Date Completed: 20000114 Latest Revision: 20221207 |
| رمز التحديث: | 20221213 |
| PMID: | 10612958 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0035-8835 |
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