دورية أكاديمية

[Delayed postanoxic encephalopathy].

التفاصيل البيبلوغرافية
العنوان: [Delayed postanoxic encephalopathy].
عنوان ترانسليتريتد: Encefalopatía postanóxica diferida.
المؤلفون: Gascón Jiménez FJ; Facultad de Medicina, Unidad Docente de Pediatría, Hospital Universitario Reina Sofía, Departamento de Pediatría, Córdoba., Navarro Gochicoa B, Velasco Jabalquinto MJ, Collantes Herrera A, Peña Rosa MJ
المصدر: Anales espanoles de pediatria [An Esp Pediatr] 2000 Aug; Vol. 53 (2), pp. 151-5.
نوع المنشور: Case Reports; Journal Article
اللغة: Spanish; Castilian
بيانات الدورية: Publisher: Doyma Country of Publication: Spain NLM ID: 0420463 Publication Model: Print Cited Medium: Print ISSN: 0302-4342 (Print) Linking ISSN: 03024342 NLM ISO Abbreviation: An Esp Pediatr Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Barcelona : Doyma
مواضيع طبية MeSH: Coma/*chemically induced , Hypoxia, Brain/*etiology , Respiratory Distress Syndrome/*chemically induced, Child ; Coma/complications ; Diagnosis, Differential ; Flumazenil/adverse effects ; GABA Modulators/adverse effects ; Humans ; Hypoxia, Brain/diagnosis ; Male ; Parkinsonian Disorders/diagnosis ; Parkinsonian Disorders/etiology ; Respiratory Distress Syndrome/complications
مستخلص: We report the case of a 9-year-old boy with delayed postanoxic encephalopathy. The patient improved after a period of coma and adult respiratory distress syndrome caused by benzodiazepine intoxication. Initial improvement appeared to be complete, but 9 days after discharge from the pediatric intensive care unit, extrapyramidal rigidity of the left arm became manifest. This event was followed by progressive neurologic impairment with involuntary, non-repetitive, but occasionally stereotyped movements, affecting distal, proximal and axial musculature in various combinations. On physical examination, passive movement of the left arm showed a plastic, lead-pipe rigidity with a ratchet-like cogwheel quality. Magnetic resonance imaging (MRI) was performed. Axial T 2 -weighted images of the brain showed characteristic signs of an ischemic area in the basal ganglia which were more evident in the right region, a finding consistent with anoxic-ischemic encephalopathy. Delayed postanoxic encephalopathy is a relatively uncommon and unexplained phenomenon which becomes manifest after an initial hypoxic-ischemic event that causes stupor or coma. The pathogenesis is unknown. Exceptionally, this syndrome can affect the basal ganglia more than the cerebral cortex and white matter. Initial improvement is followed after a variable period of time by relapse, progressing for weeks to months until the patient is left with permanent sequelae.
المشرفين على المادة: 0 (GABA Modulators)
40P7XK9392 (Flumazenil)
تواريخ الأحداث: Date Created: 20001121 Date Completed: 20010906 Latest Revision: 20201208
رمز التحديث: 20221213
PMID: 11083957
قاعدة البيانات: MEDLINE