التفاصيل البيبلوغرافية
| العنوان: |
Frontal lobe dysfunction in amyotrophic lateral sclerosis. |
| المؤلفون: |
Evdokimidis I; ENG Lab of Neurology Clinic of Athens Medical School, Aeginitio Hospital, Vas. Sofias 72-74, 11528, Athens, Greece. ievdokim@cc.uoa.gr, Constantinidis TS, Gourtzelidis P, Smyrnis N, Zalonis I, Zis PV, Andreadou E, Papageorgiou C |
| المصدر: |
Journal of the neurological sciences [J Neurol Sci] 2002 Mar 15; Vol. 195 (1), pp. 25-33. |
| نوع المنشور: |
Journal Article |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375403 Publication Model: Print Cited Medium: Print ISSN: 0022-510X (Print) Linking ISSN: 0022510X NLM ISO Abbreviation: J Neurol Sci Subsets: MEDLINE |
| أسماء مطبوعة: |
Original Publication: Amsterdam : Elsevier, <19 -> |
| مواضيع طبية MeSH: |
Amyotrophic Lateral Sclerosis/*physiopathology , Frontal Lobe/*physiopathology, Aged ; Amyotrophic Lateral Sclerosis/psychology ; Female ; Humans ; Male ; Memory ; Middle Aged ; Neuropsychological Tests ; Oculomotor Muscles/physiopathology ; Reaction Time ; Reference Values ; Saccades |
| مستخلص: |
The aim of the present study was to investigate the involvement of frontal lobe dysfunction in amyotrophic lateral sclerosis (ALS) using ocular motor paradigms and neuropsychological testing. Fifty-one patients with ALS participated in the following ocular motor tasks: (1) a three-choice task and (2) a remembered saccade task. The patients underwent a clinical and neuropsychological evaluation. One-third of ALS patients presented with signs of frontal dysfunction, as determined by their high distractibility factors (DF) in the three-choice task and their performances in both the Wisconsin and Stroop tests. ALS patients exhibited longer latencies to eye movement than controls in the performance of the remembered saccade task, specifically in performance of both remembered and delayed saccades, but saccade accuracy was not impaired. Finally, performance indices of the ocular motor tasks, in particular the DF, was correlated only with the degree of dysarthria. |
| تواريخ الأحداث: |
Date Created: 20020228 Date Completed: 20020507 Latest Revision: 20190724 |
| رمز التحديث: |
20240829 |
| DOI: |
10.1016/s0022-510x(01)00683-9 |
| PMID: |
11867070 |
| قاعدة البيانات: |
MEDLINE |
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